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The map label for this gene is exaA [H]

Identifier: 170748827

GI number: 170748827

Start: 2568007

End: 2569776

Strand: Reverse

Name: exaA [H]

Synonym: Mrad2831_2409

Alternate gene names: 170748827

Gene position: 2569776-2568007 (Counterclockwise)

Preceding gene: 170748828

Following gene: 170748826

Centisome position: 42.28

GC content: 67.51

Gene sequence:

>1770_bases
ATGAGAATGCGGACCCGGTTCCTCGCCGCGGTGGGCGTCGCCGCCCTCGTGGCGGGCGGCGCCCTGCCGGCCATGGCCCA
GGGGGTGACCGAGCAGGACATCATCAACGACGCCAAGACCCCCGGCGACGTCGTCACCTACGGGCTCGGGCCGCAGGCCC
AGCGCTTCAGCCCGCTGAAGACCCTCAACCGCGACAACATCAAGGGCCTCGTCCCGGCGTGGTCGTTCTCGTTCGGCGGC
GAGAAGCAGCGCGGCCAGGAGAGCCAGGCGCTGGTCAAGGACGGGATCATCTACGTCACGGGCTCGTACTCGCGCATGTA
CGCGATCGATTCCCGCACCGGCGACAAGAAGTGGGAGTACGACGCCCGCCTGCCGGAAGGGATCCTGCCCTGCTGCGACG
TGGTGAACCGCGGCGCCGCGCTCTACAAGGACAACGTCTACTTCGGCACGCTCGACGCCAAGCTGGTCGCGCTGAACACC
AAGACCGGCAAGGTCGTCTGGCGCAAGGACATCGACGACTTCAAGGCCGGCTACAGCTACACGGCCGCCCCGATCATCGT
GAAGGGCAAGATCATCACCGGCGTGTCGGGCGGCGAGTTCGGCGTGATCGGGCGGATCGAGGCCCGCGACGCCGAGACCG
GCGAGATCGTGTGGAAGCGGCCCGTGATCGAGGGCCACATGGGCGAGCTCAACGGCAAGCCCTCGACCATGACGGGCAAG
GTCAACGAGACCTGGCCCGGCGACATGTGGAAGTTCGGCGGCGGCGCCACGTGGCTCGGCGGCACCTACGACCCCGAGAC
CAACCTCGTCTATTTCGGCACCGGCAACCCGGGCCCGTGGAACTCCTGGCTGCGGCCGGGCGACAACAAGTGGACGTCCT
CGCGCCTCGCCCTCAACCCCGATAACGGCGAGATCGTCTGGGGCTTCCAGACCACCCCGCACGACGGCTGGGACTTCGAC
GGCGTCAACGAGTTCGTGCCGTTCGACCTGAACAAGGGCGGCAAGACCATCAAGGCCGGCGCCACCGCCGACCGCAACGG
CTTCTTCTACGTCCTCGACCGGACCAACGGGAAGTTCATCTCGGCGACGCCGTTCGTCGAGAAGATCAACTGGGCCAAGG
GCATCGACGAGAACGGCCGCCCGATCTACAACGAGGAGAACCGGCCCGGCGACCCGAGCAAGGCGACCGGCGACGACAAG
AAGGGCAAGTCGGTCTTCGCGGTGCCGAGCTTCCTCGGCGGCAAGAACTGGATGCCGATCGGCTACAGCCCCGACACCAA
GCTGTTCTACGTGCCCTCCAACGAGTGGGGCATGGATATCTGGAACGAGCCGGTGAACTACAAGAAGGGCGCCGCCTATC
TCGGCGCCGGCTTCACCATCAAGCCGGTCTTCGACGACCATATCGGCTCGCTCAAGGCGATCGACCCGACCTCCGGCAAG
GTCGTGTGGGAGTACAAGAACAAGGCCCCGCTCTGGGCCGGCGTGCTGACCACCGCGGGCAACCTCGTCTTCACCGGCAC
CCCGGAGGGCTTCCTGAAGGCCTTCGACGCCAAGACCGGCGAGGAGGTCTGGAAGTTCCAGGTCGGCACCGGCGTGGTCT
CCTCGCCGATCACCTGGGAGCAGGACGGCGAGCAGTGGGTCGGCGTCGCGGCGGGCTGGGGCGGCGCGGTGCCGCTCTGG
GGCGGCGAGGTCGCCAAGTCCACCGCCGGCATCAACCAGGGCGGCAGCTTCTGGGCGTTCAAGCTGCCGAAGACGGTGGC
GTCGCGCTGA

Upstream 100 bases:

>100_bases
AGCCTCGATCTCCAAGGGGGCGCCCCGCGACTCGTGCGGCCCGCGTCGAAACCCGGATGCCCCGGCCACACGGACCGGGG
CCGACCACGGAGGACACGTC

Downstream 100 bases:

>100_bases
AGGCCCTCAACCGAAAGCGTGCCGGCCCCCGCGGGCCGGCACGCCCAGGCTCCGGGGCAGGGCGGTCGTCTCAACACCCG
CTTGCGCCCCGGGGCCGCAT

Product: methanol/ethanol family PQQ-dependent dehydrogenase

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MRMRTRFLAAVGVAALVAGGALPAMAQGVTEQDIINDAKTPGDVVTYGLGPQAQRFSPLKTLNRDNIKGLVPAWSFSFGG
EKQRGQESQALVKDGIIYVTGSYSRMYAIDSRTGDKKWEYDARLPEGILPCCDVVNRGAALYKDNVYFGTLDAKLVALNT
KTGKVVWRKDIDDFKAGYSYTAAPIIVKGKIITGVSGGEFGVIGRIEARDAETGEIVWKRPVIEGHMGELNGKPSTMTGK
VNETWPGDMWKFGGGATWLGGTYDPETNLVYFGTGNPGPWNSWLRPGDNKWTSSRLALNPDNGEIVWGFQTTPHDGWDFD
GVNEFVPFDLNKGGKTIKAGATADRNGFFYVLDRTNGKFISATPFVEKINWAKGIDENGRPIYNEENRPGDPSKATGDDK
KGKSVFAVPSFLGGKNWMPIGYSPDTKLFYVPSNEWGMDIWNEPVNYKKGAAYLGAGFTIKPVFDDHIGSLKAIDPTSGK
VVWEYKNKAPLWAGVLTTAGNLVFTGTPEGFLKAFDAKTGEEVWKFQVGTGVVSSPITWEQDGEQWVGVAAGWGGAVPLW
GGEVAKSTAGINQGGSFWAFKLPKTVASR

Sequences:

>Translated_589_residues
MRMRTRFLAAVGVAALVAGGALPAMAQGVTEQDIINDAKTPGDVVTYGLGPQAQRFSPLKTLNRDNIKGLVPAWSFSFGG
EKQRGQESQALVKDGIIYVTGSYSRMYAIDSRTGDKKWEYDARLPEGILPCCDVVNRGAALYKDNVYFGTLDAKLVALNT
KTGKVVWRKDIDDFKAGYSYTAAPIIVKGKIITGVSGGEFGVIGRIEARDAETGEIVWKRPVIEGHMGELNGKPSTMTGK
VNETWPGDMWKFGGGATWLGGTYDPETNLVYFGTGNPGPWNSWLRPGDNKWTSSRLALNPDNGEIVWGFQTTPHDGWDFD
GVNEFVPFDLNKGGKTIKAGATADRNGFFYVLDRTNGKFISATPFVEKINWAKGIDENGRPIYNEENRPGDPSKATGDDK
KGKSVFAVPSFLGGKNWMPIGYSPDTKLFYVPSNEWGMDIWNEPVNYKKGAAYLGAGFTIKPVFDDHIGSLKAIDPTSGK
VVWEYKNKAPLWAGVLTTAGNLVFTGTPEGFLKAFDAKTGEEVWKFQVGTGVVSSPITWEQDGEQWVGVAAGWGGAVPLW
GGEVAKSTAGINQGGSFWAFKLPKTVASR
>Mature_589_residues
MRMRTRFLAAVGVAALVAGGALPAMAQGVTEQDIINDAKTPGDVVTYGLGPQAQRFSPLKTLNRDNIKGLVPAWSFSFGG
EKQRGQESQALVKDGIIYVTGSYSRMYAIDSRTGDKKWEYDARLPEGILPCCDVVNRGAALYKDNVYFGTLDAKLVALNT
KTGKVVWRKDIDDFKAGYSYTAAPIIVKGKIITGVSGGEFGVIGRIEARDAETGEIVWKRPVIEGHMGELNGKPSTMTGK
VNETWPGDMWKFGGGATWLGGTYDPETNLVYFGTGNPGPWNSWLRPGDNKWTSSRLALNPDNGEIVWGFQTTPHDGWDFD
GVNEFVPFDLNKGGKTIKAGATADRNGFFYVLDRTNGKFISATPFVEKINWAKGIDENGRPIYNEENRPGDPSKATGDDK
KGKSVFAVPSFLGGKNWMPIGYSPDTKLFYVPSNEWGMDIWNEPVNYKKGAAYLGAGFTIKPVFDDHIGSLKAIDPTSGK
VVWEYKNKAPLWAGVLTTAGNLVFTGTPEGFLKAFDAKTGEEVWKFQVGTGVVSSPITWEQDGEQWVGVAAGWGGAVPLW
GGEVAKSTAGINQGGSFWAFKLPKTVASR

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=356, Percent_Identity=26.9662921348315, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 63947; Mature: 63947

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS00364 BACTERIAL_PQQ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMRTRFLAAVGVAALVAGGALPAMAQGVTEQDIINDAKTPGDVVTYGLGPQAQRFSPLK
CCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHCCCCCCCEEEECCCCCHHHCCHHH
TLNRDNIKGLVPAWSFSFGGEKQRGQESQALVKDGIIYVTGSYSRMYAIDSRTGDKKWEY
HCCCCCCCEEECEEEECCCCCHHCCCHHHHHHHCCEEEEECCCEEEEEEECCCCCCCEEE
DARLPEGILPCCDVVNRGAALYKDNVYFGTLDAKLVALNTKTGKVVWRKDIDDFKAGYSY
CCCCCCCCHHHHHHHHCCCEEEECCEEEEECCEEEEEEECCCCCEEEECCCHHHHCCCCE
TAAPIIVKGKIITGVSGGEFGVIGRIEARDAETGEIVWKRPVIEGHMGELNGKPSTMTGK
ECCEEEEEEEEEEECCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCEEECC
VNETWPGDMWKFGGGATWLGGTYDPETNLVYFGTGNPGPWNSWLRPGDNKWTSSRLALNP
CCCCCCCCCEECCCCEEECCCCCCCCCCEEEEECCCCCCCHHCCCCCCCCCCCCEEEECC
DNGEIVWGFQTTPHDGWDFDGVNEFVPFDLNKGGKTIKAGATADRNGFFYVLDRTNGKFI
CCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCCCEEEECCCCCCCCEEEEEECCCCCEE
SATPFVEKINWAKGIDENGRPIYNEENRPGDPSKATGDDKKGKSVFAVPSFLGGKNWMPI
EECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEC
GYSPDTKLFYVPSNEWGMDIWNEPVNYKKGAAYLGAGFTIKPVFDDHIGSLKAIDPTSGK
CCCCCCEEEEEECCCCCCHHCCCCCCCCCCCEEEECCCEEEECCCCCCCCEEEECCCCCE
VVWEYKNKAPLWAGVLTTAGNLVFTGTPEGFLKAFDAKTGEEVWKFQVGTGVVSSPITWE
EEEEECCCCCEEEEHHHCCCCEEEECCCHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEC
QDGEQWVGVAAGWGGAVPLWGGEVAKSTAGINQGGSFWAFKLPKTVASR
CCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCHHHHCC
>Mature Secondary Structure
MRMRTRFLAAVGVAALVAGGALPAMAQGVTEQDIINDAKTPGDVVTYGLGPQAQRFSPLK
CCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHCCCCCCCEEEECCCCCHHHCCHHH
TLNRDNIKGLVPAWSFSFGGEKQRGQESQALVKDGIIYVTGSYSRMYAIDSRTGDKKWEY
HCCCCCCCEEECEEEECCCCCHHCCCHHHHHHHCCEEEEECCCEEEEEEECCCCCCCEEE
DARLPEGILPCCDVVNRGAALYKDNVYFGTLDAKLVALNTKTGKVVWRKDIDDFKAGYSY
CCCCCCCCHHHHHHHHCCCEEEECCEEEEECCEEEEEEECCCCCEEEECCCHHHHCCCCE
TAAPIIVKGKIITGVSGGEFGVIGRIEARDAETGEIVWKRPVIEGHMGELNGKPSTMTGK
ECCEEEEEEEEEEECCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCEEECC
VNETWPGDMWKFGGGATWLGGTYDPETNLVYFGTGNPGPWNSWLRPGDNKWTSSRLALNP
CCCCCCCCCEECCCCEEECCCCCCCCCCEEEEECCCCCCCHHCCCCCCCCCCCCEEEECC
DNGEIVWGFQTTPHDGWDFDGVNEFVPFDLNKGGKTIKAGATADRNGFFYVLDRTNGKFI
CCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCCCEEEECCCCCCCCEEEEEECCCCCEE
SATPFVEKINWAKGIDENGRPIYNEENRPGDPSKATGDDKKGKSVFAVPSFLGGKNWMPI
EECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEC
GYSPDTKLFYVPSNEWGMDIWNEPVNYKKGAAYLGAGFTIKPVFDDHIGSLKAIDPTSGK
CCCCCCEEEEEECCCCCCHHCCCCCCCCCCCEEEECCCEEEECCCCCCCCEEEECCCCCE
VVWEYKNKAPLWAGVLTTAGNLVFTGTPEGFLKAFDAKTGEEVWKFQVGTGVVSSPITWE
EEEEECCCCCEEEEHHHCCCCEEEECCCHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEC
QDGEQWVGVAAGWGGAVPLWGGEVAKSTAGINQGGSFWAFKLPKTVASR
CCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]