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The map label for this gene is tyrC [H]

Identifier: 170748292

GI number: 170748292

Start: 2002338

End: 2003279

Strand: Reverse

Name: tyrC [H]

Synonym: Mrad2831_1874

Alternate gene names: 170748292

Gene position: 2003279-2002338 (Counterclockwise)

Preceding gene: 170748293

Following gene: 170748290

Centisome position: 32.96

GC content: 73.99

Gene sequence:

>942_bases
ATGGCTGAGACATCCGAGGGCGTCCCCGCGATCGACCGCCTCGCCATCGTCGGCCTCGGGCTGATCGGCTCCTCGATCGC
CCGGGCGGCGCGGCGCTACGGCCTCGCCCGCACCATCGTGGCGGTGGACCGGGACGAGGCCGTGCGCGCCCGGGTGCGCG
ACCTCGGCATCGCCGACGTCGTCACGGGCGACCCGGCGGAGGGGGCCGCCGGCACCGACCTCGCGATCCTGTGCGTGCCG
GTGGGCGCCATCGGGGCGGCGGCGGCCGAGATGGCGCCTTACCTCAAGCCCGGCGCGATCGTGTCGGATGTCGGTTCGGT
GAAGGGTGCCGTGGTGGCGGCGGTCCGGCCGCACCTGCCCGACGGCGTCGCGCTGGTCCCCGGCCACCCGATCGCCGGCA
CCGAGTTCTCGGGCCCGGACGCGGGCTTCGCGACCCTGTTCCAGGGCCGCTGGTGCATCCTGACCCCGCCCGAGGGCACC
GACCCGGCCGCGATCGAGACCGTCCGCGCCCTGTGGGCGGGGATGGGCGCCGACGTCGAGACGATGAGCGCCGAGCACCA
CGACCACGTGCTCGCCATCACCAGCCACCTGCCGCACCTGATCGCCTACAACATCGTGGGCACCGCGGCCGACCTCGAAT
CGGCGACGCAGTCCGAGGTGATCAAGTTCTCGGCGAGCGGGTTCCGCGACTTCACCCGCATCGCGGCGTCGGACCCGACC
ATGTGGCGGGACATCTTCCTCAACAACCGCGACGCGGTGCTGGAGATGCTCGGCCGGTTCAACGAGGACCTGTCGGCGCT
CGCCAAGGCGGTGCGCTGGGGCGACGGCGACGCGCTCCACGCGATGTTCACCCGCACCCGGGCGATCCGGCGCAGCATCG
TGGCGCAGGGCCAGGAGACCGCGGCCCCGGATTTCGGCCGGCCGCGGCCGCCGGAGGAGTAG

Upstream 100 bases:

>100_bases
ACCGCCTACGGCCTGCCCAACGCCCTGCGGGTGACGGTGGCGGGCGCCGAGGCGAACGAAGCCTTCCTGGCGGCGCTCGG
CGACTTCGTGCGGGGCCACC

Downstream 100 bases:

>100_bases
GGACCGCCGGCGCTCACGCCGGCGGGCGGTTGACCAGCACCGGCTGCGCCGCCGCCCGCTCCGGGAACAGGTGCTTCAGG
GCTTCGAGCTTCGGCGCGTC

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: Arogenate dehydrogenase; ADH; Cyclohexadienyl dehydrogenase; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MAETSEGVPAIDRLAIVGLGLIGSSIARAARRYGLARTIVAVDRDEAVRARVRDLGIADVVTGDPAEGAAGTDLAILCVP
VGAIGAAAAEMAPYLKPGAIVSDVGSVKGAVVAAVRPHLPDGVALVPGHPIAGTEFSGPDAGFATLFQGRWCILTPPEGT
DPAAIETVRALWAGMGADVETMSAEHHDHVLAITSHLPHLIAYNIVGTAADLESATQSEVIKFSASGFRDFTRIAASDPT
MWRDIFLNNRDAVLEMLGRFNEDLSALAKAVRWGDGDALHAMFTRTRAIRRSIVAQGQETAAPDFGRPRPPEE

Sequences:

>Translated_313_residues
MAETSEGVPAIDRLAIVGLGLIGSSIARAARRYGLARTIVAVDRDEAVRARVRDLGIADVVTGDPAEGAAGTDLAILCVP
VGAIGAAAAEMAPYLKPGAIVSDVGSVKGAVVAAVRPHLPDGVALVPGHPIAGTEFSGPDAGFATLFQGRWCILTPPEGT
DPAAIETVRALWAGMGADVETMSAEHHDHVLAITSHLPHLIAYNIVGTAADLESATQSEVIKFSASGFRDFTRIAASDPT
MWRDIFLNNRDAVLEMLGRFNEDLSALAKAVRWGDGDALHAMFTRTRAIRRSIVAQGQETAAPDFGRPRPPEE
>Mature_312_residues
AETSEGVPAIDRLAIVGLGLIGSSIARAARRYGLARTIVAVDRDEAVRARVRDLGIADVVTGDPAEGAAGTDLAILCVPV
GAIGAAAAEMAPYLKPGAIVSDVGSVKGAVVAAVRPHLPDGVALVPGHPIAGTEFSGPDAGFATLFQGRWCILTPPEGTD
PAAIETVRALWAGMGADVETMSAEHHDHVLAITSHLPHLIAYNIVGTAADLESATQSEVIKFSASGFRDFTRIAASDPTM
WRDIFLNNRDAVLEMLGRFNEDLSALAKAVRWGDGDALHAMFTRTRAIRRSIVAQGQETAAPDFGRPRPPEE

Specific function: Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase [H]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.43; =1.3.1.12 [H]

Molecular weight: Translated: 32797; Mature: 32665

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETSEGVPAIDRLAIVGLGLIGSSIARAARRYGLARTIVAVDRDEAVRARVRDLGIADV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCHHHHHHHHHHCCCHHE
VTGDPAEGAAGTDLAILCVPVGAIGAAAAEMAPYLKPGAIVSDVGSVKGAVVAAVRPHLP
ECCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEECCCCC
DGVALVPGHPIAGTEFSGPDAGFATLFQGRWCILTPPEGTDPAAIETVRALWAGMGADVE
CCEEEECCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCHH
TMSAEHHDHVLAITSHLPHLIAYNIVGTAADLESATQSEVIKFSASGFRDFTRIAASDPT
HHCCCCCCCEEEHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
MWRDIFLNNRDAVLEMLGRFNEDLSALAKAVRWGDGDALHAMFTRTRAIRRSIVAQGQET
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
AAPDFGRPRPPEE
CCCCCCCCCCCCC
>Mature Secondary Structure 
AETSEGVPAIDRLAIVGLGLIGSSIARAARRYGLARTIVAVDRDEAVRARVRDLGIADV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCHHHHHHHHHHCCCHHE
VTGDPAEGAAGTDLAILCVPVGAIGAAAAEMAPYLKPGAIVSDVGSVKGAVVAAVRPHLP
ECCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEECCCCC
DGVALVPGHPIAGTEFSGPDAGFATLFQGRWCILTPPEGTDPAAIETVRALWAGMGADVE
CCEEEECCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCHH
TMSAEHHDHVLAITSHLPHLIAYNIVGTAADLESATQSEVIKFSASGFRDFTRIAASDPT
HHCCCCCCCEEEHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
MWRDIFLNNRDAVLEMLGRFNEDLSALAKAVRWGDGDALHAMFTRTRAIRRSIVAQGQET
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
AAPDFGRPRPPEE
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916685 [H]