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The map label for this gene is mcpA [H]

Identifier: 170747234

GI number: 170747234

Start: 841811

End: 843907

Strand: Reverse

Name: mcpA [H]

Synonym: Mrad2831_0800

Alternate gene names: 170747234

Gene position: 843907-841811 (Counterclockwise)

Preceding gene: 170747235

Following gene: 170747233

Centisome position: 13.88

GC content: 76.35

Gene sequence:

>2097_bases
ATGCGCGTACGGGACCTGTCCATCCGGACGACGATGAGCCTCGTCCTCGTCGTCATGGCCACGATTCTGCTCGGCTTCGC
GACGGGCACCGTGCGGGAGGCGCGGCAGCAGGCCGCCGAGGCCGACCGGGTCATCGCGCTGGTGCGGGCGAGCCGCGCCC
TCCTCCAGACGCTGAACGTAACCCGGTTCGAGCGGGGCGCGACACTGCAGTTCCTGGCCGCCGCCGAGCCGGTCGAGGCC
GAGACCCGCGCGTCGCTCTACGCCGACCGGGAGCGGGCGGTCGCGGGGCTCGCCGCGGCGCGGCCGCTCCTCGACGGGCT
GGAACTTCCCGCCGTGACGGCGACCCTCGGCCGGCTGCACGAGGCGAGCGGACGCGTCGAGCGCCTCCGGCCGCGGGTCG
ACGCGGTTCTGAATGTGTCGGGCGCGCAGCGCGACGGCGCGGTGATGGCGGAGGCGAGGGCCGCCTTCCAGGCCATGCTC
GATGCCCTGATCGCGACCAGCGACGCCGTGGACGGCGCGATCCCGCTGTCCGACGCGATCCTCCGGCGCGACCTCGCCCT
GAAGCGGGCGGCGTGGGCGACCCGCATGGCCAACGGCGCCGTCGCGCTGCGCGTGCAGACGTCGCTGGCGGCCGGGGCAT
CGTGGTCGCTGGACGAGACCGTCGCGGCCGCCGAGGAGCGGGGACGGCTCGACGCGGCGTGGAGCGCGGCGACCGAGGCG
GCGGCCGAGGCCTCGGAGACGGTCGGGGCCGCGTTCCGGCGGGCCGGGGAGAACAATTTCGCGGGTAGCCCCCTCGCCCG
CCGGCGCGCCGTGGCGCAGGCACTGGCTCGCGGCGCGCCGCCGGGGCTGACGCTCGCGCAGGCGCGCAAGCTCGACACGC
CCGAGCAGGTCACCCTCGTCGACCTCGCCTTCGTCTGCCTCGACGAGATGGTCGCGCGGGCCGAGACCCTGGCCAACGCG
GCGCGCAGCACCCTGTGGCGCGACGGAGCGGCCCTGGTCGCAACCCTGCTGCTCGTCGCGCTCGGTCTGCTCGCCCTGTT
CCGCGGCGTGCTGCGGCCGATCCGGGTGATCACTGCGGCCATGGAGGCCCTCGCGGCCGGAAACGCCGCCGTGGCCGTCC
CGGGTCTGAGGCGGCGCAACGAGATCGGCGCCATGGCGGCGGCCGTGCAGGTGTTCAAGGACAACCTGATCCGCAGCCGG
CAGCTCGAGGCCGAGGCCGAGGCGGCCCGGCAGGACGCGGAGCGCCAGCGCAGCCTCGTCATGCGGCAGATCGCCGATCG
GTTCGCCGACACCGTCGGCGGGATCGTCGCGCAGGTCTCGGCCGCGGCGACCGGCCTGCAGGCGACGGCCCGGAGCATGA
CCGAGACCGCCGCGCAGACCGCCGAGCAGTCGAGCACCGTCGCGGCCGCGGCCGAGCAGGCGGCCAGCAATGTCGGCACC
GTGGCGGCGGCGGCCGAGGAGCTCGGCACCTCGGTCCAGGAGATCGGCCGGCAGGTCGACGGCTCGGCCAGCCTCGCGCG
CGCGGCCGTCGCCGAGGCCGATCAGACCGGCGCGCTGGTCCAGGAGCTGAGCGAGGCGGTGACGCGGATCGGCGACGTGG
TCGGGCTGATCTCGACCATCGCGGGCCAGACCAACCTGCTGGCGCTCAACGCCACGATCGAGGCCGCGCGTGCCGGTGCG
GCCGGTCGCGGTTTCGCCGTCGTGGCCACCGAGGTGAAGGCGCTGGCCGAGCAGACCGCCCGGGCGACCGAGGAGATCGC
CGGCCAGATCGGGCGGGTCCAGGCCTCGACCGGTCAGGCGGTGGCGGCGATCGGGACGATCACGGCGCGGATCCGCGACA
TCGACGGCGTCGCGACCTCCATCGCGGCGGCGGTCGAGCAGCAGGGCGCGGCCACCCACGAGATCGTCCGCAACGTCGGG
CAGGCGGCGCAGGGCGCGGCCGCGGTCACCGGCCACGTCGCCGGCGTCGCCGCGGCCTCCGGCGCGACCGAGGCGGCCGC
GGGCGAGGTCCTGGGCGCGGCCGCCGCCCTGTCGACCCAGGCCGTGCAGCTGACCGCCGAGGTCGGCCGCTTCCTCGACG
GCGTCCGGGCCGCCTGA

Upstream 100 bases:

>100_bases
GGACGCTGCCTGCATCCTCGCGCGTTGCCCGGATCGTGCCGGGAAAAACTTGCTATGATTTGGTTCGCCCGGCCGATCGG
GCGACCGGAGACCAGGCACG

Downstream 100 bases:

>100_bases
GAGCGCCCCGGGGGGCACCAACCGTCTCTCCCTGGCCTGGACGGGTCCGAGGCGATAGAAGGCCTCCCGACGGCCGGCGC
GCACGGCGCCGGCTCCAGGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MRVRDLSIRTTMSLVLVVMATILLGFATGTVREARQQAAEADRVIALVRASRALLQTLNVTRFERGATLQFLAAAEPVEA
ETRASLYADRERAVAGLAAARPLLDGLELPAVTATLGRLHEASGRVERLRPRVDAVLNVSGAQRDGAVMAEARAAFQAML
DALIATSDAVDGAIPLSDAILRRDLALKRAAWATRMANGAVALRVQTSLAAGASWSLDETVAAAEERGRLDAAWSAATEA
AAEASETVGAAFRRAGENNFAGSPLARRRAVAQALARGAPPGLTLAQARKLDTPEQVTLVDLAFVCLDEMVARAETLANA
ARSTLWRDGAALVATLLLVALGLLALFRGVLRPIRVITAAMEALAAGNAAVAVPGLRRRNEIGAMAAAVQVFKDNLIRSR
QLEAEAEAARQDAERQRSLVMRQIADRFADTVGGIVAQVSAAATGLQATARSMTETAAQTAEQSSTVAAAAEQAASNVGT
VAAAAEELGTSVQEIGRQVDGSASLARAAVAEADQTGALVQELSEAVTRIGDVVGLISTIAGQTNLLALNATIEAARAGA
AGRGFAVVATEVKALAEQTARATEEIAGQIGRVQASTGQAVAAIGTITARIRDIDGVATSIAAAVEQQGAATHEIVRNVG
QAAQGAAAVTGHVAGVAAASGATEAAAGEVLGAAAALSTQAVQLTAEVGRFLDGVRAA

Sequences:

>Translated_698_residues
MRVRDLSIRTTMSLVLVVMATILLGFATGTVREARQQAAEADRVIALVRASRALLQTLNVTRFERGATLQFLAAAEPVEA
ETRASLYADRERAVAGLAAARPLLDGLELPAVTATLGRLHEASGRVERLRPRVDAVLNVSGAQRDGAVMAEARAAFQAML
DALIATSDAVDGAIPLSDAILRRDLALKRAAWATRMANGAVALRVQTSLAAGASWSLDETVAAAEERGRLDAAWSAATEA
AAEASETVGAAFRRAGENNFAGSPLARRRAVAQALARGAPPGLTLAQARKLDTPEQVTLVDLAFVCLDEMVARAETLANA
ARSTLWRDGAALVATLLLVALGLLALFRGVLRPIRVITAAMEALAAGNAAVAVPGLRRRNEIGAMAAAVQVFKDNLIRSR
QLEAEAEAARQDAERQRSLVMRQIADRFADTVGGIVAQVSAAATGLQATARSMTETAAQTAEQSSTVAAAAEQAASNVGT
VAAAAEELGTSVQEIGRQVDGSASLARAAVAEADQTGALVQELSEAVTRIGDVVGLISTIAGQTNLLALNATIEAARAGA
AGRGFAVVATEVKALAEQTARATEEIAGQIGRVQASTGQAVAAIGTITARIRDIDGVATSIAAAVEQQGAATHEIVRNVG
QAAQGAAAVTGHVAGVAAASGATEAAAGEVLGAAAALSTQAVQLTAEVGRFLDGVRAA
>Mature_698_residues
MRVRDLSIRTTMSLVLVVMATILLGFATGTVREARQQAAEADRVIALVRASRALLQTLNVTRFERGATLQFLAAAEPVEA
ETRASLYADRERAVAGLAAARPLLDGLELPAVTATLGRLHEASGRVERLRPRVDAVLNVSGAQRDGAVMAEARAAFQAML
DALIATSDAVDGAIPLSDAILRRDLALKRAAWATRMANGAVALRVQTSLAAGASWSLDETVAAAEERGRLDAAWSAATEA
AAEASETVGAAFRRAGENNFAGSPLARRRAVAQALARGAPPGLTLAQARKLDTPEQVTLVDLAFVCLDEMVARAETLANA
ARSTLWRDGAALVATLLLVALGLLALFRGVLRPIRVITAAMEALAAGNAAVAVPGLRRRNEIGAMAAAVQVFKDNLIRSR
QLEAEAEAARQDAERQRSLVMRQIADRFADTVGGIVAQVSAAATGLQATARSMTETAAQTAEQSSTVAAAAEQAASNVGT
VAAAAEELGTSVQEIGRQVDGSASLARAAVAEADQTGALVQELSEAVTRIGDVVGLISTIAGQTNLLALNATIEAARAGA
AGRGFAVVATEVKALAEQTARATEEIAGQIGRVQASTGQAVAAIGTITARIRDIDGVATSIAAAVEQQGAATHEIVRNVG
QAAQGAAAVTGHVAGVAAASGATEAAAGEVLGAAAALSTQAVQLTAEVGRFLDGVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=306, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787690, Length=444, Percent_Identity=29.5045045045045, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788195, Length=300, Percent_Identity=30.3333333333333, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI2367378, Length=225, Percent_Identity=32.4444444444444, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789453, Length=330, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 71370; Mature: 71370

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRDLSIRTTMSLVLVVMATILLGFATGTVREARQQAAEADRVIALVRASRALLQTLNV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRFERGATLQFLAAAEPVEAETRASLYADRERAVAGLAAARPLLDGLELPAVTATLGRLH
HHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
EASGRVERLRPRVDAVLNVSGAQRDGAVMAEARAAFQAMLDALIATSDAVDGAIPLSDAI
HHCCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LRRDLALKRAAWATRMANGAVALRVQTSLAAGASWSLDETVAAAEERGRLDAAWSAATEA
HHHHHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
AAEASETVGAAFRRAGENNFAGSPLARRRAVAQALARGAPPGLTLAQARKLDTPEQVTLV
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHH
DLAFVCLDEMVARAETLANAARSTLWRDGAALVATLLLVALGLLALFRGVLRPIRVITAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEALAAGNAAVAVPGLRRRNEIGAMAAAVQVFKDNLIRSRQLEAEAEAARQDAERQRSLV
HHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRQIADRFADTVGGIVAQVSAAATGLQATARSMTETAAQTAEQSSTVAAAAEQAASNVGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAAAEELGTSVQEIGRQVDGSASLARAAVAEADQTGALVQELSEAVTRIGDVVGLISTI
HHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQTNLLALNATIEAARAGAAGRGFAVVATEVKALAEQTARATEEIAGQIGRVQASTGQA
CCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCH
VAAIGTITARIRDIDGVATSIAAAVEQQGAATHEIVRNVGQAAQGAAAVTGHVAGVAAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
GATEAAAGEVLGAAAALSTQAVQLTAEVGRFLDGVRAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVRDLSIRTTMSLVLVVMATILLGFATGTVREARQQAAEADRVIALVRASRALLQTLNV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRFERGATLQFLAAAEPVEAETRASLYADRERAVAGLAAARPLLDGLELPAVTATLGRLH
HHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
EASGRVERLRPRVDAVLNVSGAQRDGAVMAEARAAFQAMLDALIATSDAVDGAIPLSDAI
HHCCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LRRDLALKRAAWATRMANGAVALRVQTSLAAGASWSLDETVAAAEERGRLDAAWSAATEA
HHHHHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
AAEASETVGAAFRRAGENNFAGSPLARRRAVAQALARGAPPGLTLAQARKLDTPEQVTLV
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHH
DLAFVCLDEMVARAETLANAARSTLWRDGAALVATLLLVALGLLALFRGVLRPIRVITAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEALAAGNAAVAVPGLRRRNEIGAMAAAVQVFKDNLIRSRQLEAEAEAARQDAERQRSLV
HHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRQIADRFADTVGGIVAQVSAAATGLQATARSMTETAAQTAEQSSTVAAAAEQAASNVGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAAAEELGTSVQEIGRQVDGSASLARAAVAEADQTGALVQELSEAVTRIGDVVGLISTI
HHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQTNLLALNATIEAARAGAAGRGFAVVATEVKALAEQTARATEEIAGQIGRVQASTGQA
CCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCH
VAAIGTITARIRDIDGVATSIAAAVEQQGAATHEIVRNVGQAAQGAAAVTGHVAGVAAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
GATEAAAGEVLGAAAALSTQAVQLTAEVGRFLDGVRAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]