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The map label for this gene is icfA [H]

Identifier: 170078601

GI number: 170078601

Start: 2077747

End: 2078496

Strand: Direct

Name: icfA [H]

Synonym: SYNPCC7002_A1997

Alternate gene names: 170078601

Gene position: 2077747-2078496 (Clockwise)

Preceding gene: 170078597

Following gene: 170078606

Centisome position: 69.07

GC content: 51.2

Gene sequence:

>750_bases
GTGAAAAAACTTATTCGCGGCCTGGACAAATTTAAGCAAAGCTATGTTGCGAGCCACCAGGATCTTTTTGAACAACTTTC
CCACGGCCAAAAGCCCCGCGTTCTGTTCATTTGTTGCTCCGACTCCCGTGTTGACCCGGCGCTGATTACCCAAACGGATA
TTGGTGAAATCTTCGTCATCCGCAATGCCGGAAATATTATTCCTCCCTATGGTGCGGCCAATGGCGGCGAAGGGGGCACC
CTAGAATATGCTCTCCAAGGCCTCGATATTCGGCAAATTATTGTCTGTGGCCATTCCCACTGTGGCGCGATGAAAGGGCT
GCTTAAATTAAATAAACTCCAAGCGGATATGCCTTTGGTTTACGATTGGCTCAAGCACGCCGAAGCCACCCGTCGCCTCG
TCCGGGATACTTACCCCCACTGCGAAGGGGAAGAACTGGTCGAAACCCTCGTTGCGGAAAATGTCCTTGTTCAGATTGAT
AATCTCAAAACCTATCCCGTGGTGCGATCGCGGCTCCACCAGGGCAAGCTGAAAATCTATGGCTGGATCTACAACATCGA
AAATGGCGAAGTGTTAGCCTACGACGAAACAAAACACGCCTATGTGAAGCCAGACTATAGCCTCATCGACGAAACCCCCT
TAACGGAGCGTGAAGCCCTAGAAGGTTGCCCACTTCCCTACACCGTCGCTTCTGGCCAGAGTTTAGCGGGTTGGTACGGC
GAAACTGATACCTTCTCTGTGAGTGGTTAG

Upstream 100 bases:

>100_bases
TTATGAAAAATATGTGCCATCCTCATTTATCTAAATGGATTATTTTGGTTTACTATGATTCCTCAGTAGTCACCTCGTTT
TGACATCGGACGATCGAACA

Downstream 100 bases:

>100_bases
GCTGCCATACAAATTTTTTTTGATCCCTGGGGCGATCGCCAATGTTAAGCGAGTTCGATGGGAATGTAGGCCTGAAAATT
TTTAAAATCTTGGTCTTCTG

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKKLIRGLDKFKQSYVASHQDLFEQLSHGQKPRVLFICCSDSRVDPALITQTDIGEIFVIRNAGNIIPPYGAANGGEGGT
LEYALQGLDIRQIIVCGHSHCGAMKGLLKLNKLQADMPLVYDWLKHAEATRRLVRDTYPHCEGEELVETLVAENVLVQID
NLKTYPVVRSRLHQGKLKIYGWIYNIENGEVLAYDETKHAYVKPDYSLIDETPLTEREALEGCPLPYTVASGQSLAGWYG
ETDTFSVSG

Sequences:

>Translated_249_residues
MKKLIRGLDKFKQSYVASHQDLFEQLSHGQKPRVLFICCSDSRVDPALITQTDIGEIFVIRNAGNIIPPYGAANGGEGGT
LEYALQGLDIRQIIVCGHSHCGAMKGLLKLNKLQADMPLVYDWLKHAEATRRLVRDTYPHCEGEELVETLVAENVLVQID
NLKTYPVVRSRLHQGKLKIYGWIYNIENGEVLAYDETKHAYVKPDYSLIDETPLTEREALEGCPLPYTVASGQSLAGWYG
ETDTFSVSG
>Mature_249_residues
MKKLIRGLDKFKQSYVASHQDLFEQLSHGQKPRVLFICCSDSRVDPALITQTDIGEIFVIRNAGNIIPPYGAANGGEGGT
LEYALQGLDIRQIIVCGHSHCGAMKGLLKLNKLQADMPLVYDWLKHAEATRRLVRDTYPHCEGEELVETLVAENVLVQID
NLKTYPVVRSRLHQGKLKIYGWIYNIENGEVLAYDETKHAYVKPDYSLIDETPLTEREALEGCPLPYTVASGQSLAGWYG
ETDTFSVSG

Specific function: Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation [H]

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=202, Percent_Identity=42.0792079207921, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI1786318, Length=177, Percent_Identity=31.638418079096, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25147564, Length=250, Percent_Identity=27.6, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115532990, Length=254, Percent_Identity=25.5905511811024, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324292, Length=175, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24645213, Length=246, Percent_Identity=26.8292682926829, Blast_Score=94, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 27798; Mature: 27798

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLIRGLDKFKQSYVASHQDLFEQLSHGQKPRVLFICCSDSRVDPALITQTDIGEIFVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEE
RNAGNIIPPYGAANGGEGGTLEYALQGLDIRQIIVCGHSHCGAMKGLLKLNKLQADMPLV
ECCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCHHH
YDWLKHAEATRRLVRDTYPHCEGEELVETLVAENVLVQIDNLKTYPVVRSRLHQGKLKIY
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCEEEE
GWIYNIENGEVLAYDETKHAYVKPDYSLIDETPLTEREALEGCPLPYTVASGQSLAGWYG
EEEEEECCCCEEEEECCCCEEECCCHHHHCCCCCCHHHHHCCCCCCEEECCCCCCCCCCC
ETDTFSVSG
CCCEEEECC
>Mature Secondary Structure
MKKLIRGLDKFKQSYVASHQDLFEQLSHGQKPRVLFICCSDSRVDPALITQTDIGEIFVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEE
RNAGNIIPPYGAANGGEGGTLEYALQGLDIRQIIVCGHSHCGAMKGLLKLNKLQADMPLV
ECCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCHHH
YDWLKHAEATRRLVRDTYPHCEGEELVETLVAENVLVQIDNLKTYPVVRSRLHQGKLKIY
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCEEEE
GWIYNIENGEVLAYDETKHAYVKPDYSLIDETPLTEREALEGCPLPYTVASGQSLAGWYG
EEEEEECCCCEEEEECCCCEEECCCHHHHCCCCCCHHHHHCCCCCCEEECCCCCCCCCCC
ETDTFSVSG
CCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584776 [H]