Click here to switch to the map view.

The map label for this gene is fabB [H]

Identifier: 170077623

GI number: 170077623

Start: 1033954

End: 1035090

Strand: Reverse

Name: fabB [H]

Synonym: SYNPCC7002_A1002

Alternate gene names: 170077623

Gene position: 1035090-1033954 (Counterclockwise)

Preceding gene: 170077625

Following gene: 170077607

Centisome position: 34.41

GC content: 52.59

Gene sequence:

>1137_bases
ATGGTGCGGGTAGTGATAACGGGCCTGGGTTTACGCTGTGCCCTGGGCGATCGCCACCAGGCTTGGCAAAAATTACAACG
GGGAGAAAGCGCGATCCAATTGCGGCAACCGTTTCGGGATTTACCCGTTATTCCGGTGGCGATGTTGGGGAAAGAACCTA
TAGATTTAGAAATTTTGCGGCGATCGCTCGTTGAGGCGACCCTCGTAGATGCTGGCCTAGAACCGCCTTTAGAACATTGC
GGGATTGTGATCGGCTCCAGTCGGGGCTTTCAGGGGCAGTGGGAAAAGCTGCGGTACGACGACCAACAAGGACATCAGAG
GGGATTAGAGAATTGGTTAACTTATTTACCCAACCAATTGGCGATCGCCACGGCCCAGCAAGTCGGCTCCCAAGGGCCAG
TTTTAGCACCGATGGGGGCTTGTACCACCGGATTATGGGCGATCGCCCAGGGCTTTGAACTTTTGCAACGGGGCGATCGC
CCACAGGTGTTAGCCGGAGCAGTGGAATCTCCCGTCACGCCTTTGAGTATTACGGGGTTCCAGAAAATGGGGGCTTTGGC
GACGACGGGCTGTTTTCCCTTTGACCAACGGCGAGAAGGTTTGGTTTTAGGGGAAGGGGGGGCGATCTTTCTGCTCGAAA
CCCTAGAATCGGCCCAGCAACGAAACGCCAAAATTTACGGCGAAATCCTTGGCTGGAGTTTTACCTGTGATGCCCACCAC
ATGAGCGCGCCCCAAGGTAATTATCAGGTCGCAATGAAGGCGATCGCCCAATGTTTAGATTGGGCTGGCCTGGAACCCGA
AAATATAGATCACATTCATCCCCACGGCACCAGTACCCGTTTAAATGATCAAGCCGAAGCAACGATGATCGAAATGCTAT
TTCCCCACCGTCCTTTTGTCAGTGGTAGTAAAGGGGCAACGGGTCACACCCTCGGCGCATCGGGAGCTTTGGGGGTTGCG
TTCTCGCTGTTAATGTTGCGGGAGCAACGGCTTTTTCCCTGTGTAGGCTTAGAACAATCAGAATTTGACTTAAATTTCGT
CATGAAAGCCCAGAATACTCCACTCCGAAATGCTCTTTGTTTTAGCTTTGGGTTTGGTGGCCAAAATGGGGCGATCGCCC
TTCAAAAATATTTTTGA

Upstream 100 bases:

>100_bases
TTGGTGAGAATAATCGGTTGCAACATCCTACGGTAACGGCGATCGCCAGAAATCGACAGGCTGACGCAAAATTTTTGATG
CTTAGTGACGGGATATTGAT

Downstream 100 bases:

>100_bases
GGGATTCAGAATTTATGTACCAAACTAATCAAATCTTGGTAAACCACTCGGCATCAACATCGACTGACTCAATCAAATTG
ATTTTGACCCCTAGGCCAAG

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MVRVVITGLGLRCALGDRHQAWQKLQRGESAIQLRQPFRDLPVIPVAMLGKEPIDLEILRRSLVEATLVDAGLEPPLEHC
GIVIGSSRGFQGQWEKLRYDDQQGHQRGLENWLTYLPNQLAIATAQQVGSQGPVLAPMGACTTGLWAIAQGFELLQRGDR
PQVLAGAVESPVTPLSITGFQKMGALATTGCFPFDQRREGLVLGEGGAIFLLETLESAQQRNAKIYGEILGWSFTCDAHH
MSAPQGNYQVAMKAIAQCLDWAGLEPENIDHIHPHGTSTRLNDQAEATMIEMLFPHRPFVSGSKGATGHTLGASGALGVA
FSLLMLREQRLFPCVGLEQSEFDLNFVMKAQNTPLRNALCFSFGFGGQNGAIALQKYF

Sequences:

>Translated_378_residues
MVRVVITGLGLRCALGDRHQAWQKLQRGESAIQLRQPFRDLPVIPVAMLGKEPIDLEILRRSLVEATLVDAGLEPPLEHC
GIVIGSSRGFQGQWEKLRYDDQQGHQRGLENWLTYLPNQLAIATAQQVGSQGPVLAPMGACTTGLWAIAQGFELLQRGDR
PQVLAGAVESPVTPLSITGFQKMGALATTGCFPFDQRREGLVLGEGGAIFLLETLESAQQRNAKIYGEILGWSFTCDAHH
MSAPQGNYQVAMKAIAQCLDWAGLEPENIDHIHPHGTSTRLNDQAEATMIEMLFPHRPFVSGSKGATGHTLGASGALGVA
FSLLMLREQRLFPCVGLEQSEFDLNFVMKAQNTPLRNALCFSFGFGGQNGAIALQKYF
>Mature_378_residues
MVRVVITGLGLRCALGDRHQAWQKLQRGESAIQLRQPFRDLPVIPVAMLGKEPIDLEILRRSLVEATLVDAGLEPPLEHC
GIVIGSSRGFQGQWEKLRYDDQQGHQRGLENWLTYLPNQLAIATAQQVGSQGPVLAPMGACTTGLWAIAQGFELLQRGDR
PQVLAGAVESPVTPLSITGFQKMGALATTGCFPFDQRREGLVLGEGGAIFLLETLESAQQRNAKIYGEILGWSFTCDAHH
MSAPQGNYQVAMKAIAQCLDWAGLEPENIDHIHPHGTSTRLNDQAEATMIEMLFPHRPFVSGSKGATGHTLGASGALGVA
FSLLMLREQRLFPCVGLEQSEFDLNFVMKAQNTPLRNALCFSFGFGGQNGAIALQKYF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=414, Percent_Identity=34.2995169082126, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI223972627, Length=147, Percent_Identity=42.8571428571429, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI41872631, Length=368, Percent_Identity=25.8152173913043, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1787337, Length=408, Percent_Identity=33.3333333333333, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1788663, Length=415, Percent_Identity=29.3975903614458, Blast_Score=142, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71983541, Length=275, Percent_Identity=32.7272727272727, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71983535, Length=260, Percent_Identity=33.0769230769231, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17550940, Length=307, Percent_Identity=26.0586319218241, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI212642053, Length=261, Percent_Identity=24.1379310344828, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=30.7174887892377, Blast_Score=165, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24644341, Length=418, Percent_Identity=33.0143540669856, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI221330659, Length=343, Percent_Identity=25.3644314868805, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19920632, Length=343, Percent_Identity=25.3644314868805, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41188; Mature: 41188

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00606 B_KETOACYL_SYNTHASE ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRVVITGLGLRCALGDRHQAWQKLQRGESAIQLRQPFRDLPVIPVAMLGKEPIDLEILR
CEEEEEECCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHH
RSLVEATLVDAGLEPPLEHCGIVIGSSRGFQGQWEKLRYDDQQGHQRGLENWLTYLPNQL
HHHHHHHHHHCCCCCCHHHCCEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCHH
AIATAQQVGSQGPVLAPMGACTTGLWAIAQGFELLQRGDRPQVLAGAVESPVTPLSITGF
HHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEECCH
QKMGALATTGCFPFDQRREGLVLGEGGAIFLLETLESAQQRNAKIYGEILGWSFTCDAHH
HHHCCHHHCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHCCCEEEEEEECEEEEECCHH
MSAPQGNYQVAMKAIAQCLDWAGLEPENIDHIHPHGTSTRLNDQAEATMIEMLFPHRPFV
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
SGSKGATGHTLGASGALGVAFSLLMLREQRLFPCVGLEQSEFDLNFVMKAQNTPLRNALC
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHEEE
FSFGFGGQNGAIALQKYF
EEECCCCCCCCEEEEECC
>Mature Secondary Structure
MVRVVITGLGLRCALGDRHQAWQKLQRGESAIQLRQPFRDLPVIPVAMLGKEPIDLEILR
CEEEEEECCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHH
RSLVEATLVDAGLEPPLEHCGIVIGSSRGFQGQWEKLRYDDQQGHQRGLENWLTYLPNQL
HHHHHHHHHHCCCCCCHHHCCEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCHH
AIATAQQVGSQGPVLAPMGACTTGLWAIAQGFELLQRGDRPQVLAGAVESPVTPLSITGF
HHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEECCH
QKMGALATTGCFPFDQRREGLVLGEGGAIFLLETLESAQQRNAKIYGEILGWSFTCDAHH
HHHCCHHHCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHCCCEEEEEEECEEEEECCHH
MSAPQGNYQVAMKAIAQCLDWAGLEPENIDHIHPHGTSTRLNDQAEATMIEMLFPHRPFV
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
SGSKGATGHTLGASGALGVAFSLLMLREQRLFPCVGLEQSEFDLNFVMKAQNTPLRNALC
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHEEE
FSFGFGGQNGAIALQKYF
EEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]