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The map label for this gene is pntA [H]

Identifier: 170077607

GI number: 170077607

Start: 1013769

End: 1014914

Strand: Reverse

Name: pntA [H]

Synonym: SYNPCC7002_A0986

Alternate gene names: 170077607

Gene position: 1014914-1013769 (Counterclockwise)

Preceding gene: 170077623

Following gene: 170077606

Centisome position: 33.74

GC content: 54.45

Gene sequence:

>1146_bases
ATGAAAATTGCTGTTGCTCGGGAAACCGTTGCCGGAGAACGTCGGGTAGCCCTGACACCGGATCAGGTTTCTCGTCTTGT
TAAAAAAGGCTGGGAAATCCATGTGGAGGCCGGGGCTGGTGAGGCATCTCTCCTTCCCGATGCTGCCTATGAGGAAGCTG
GGGCAAAAGTCGTTGGCGATCGTCAATCCCTCTGGAAAGAGGCTGATCTCCTCGTCAAGGTGGCTGTACCCACAGAAGAA
GAGGTTGCCCTCCTGCCGGAAGGGTCAATGGTGGCGAGTTTGCTCAATCCCCTGGGACAACCAGAGATTATTCAAAAATT
AGCAGATAAAAAGATAACCGCCTTGGGCATGGAGTTGATCCCCCGCACCAGTCGCGCCCAAAGTATGGATGTGTTGTCTT
CCCAGGCTGGGGTGGCTGGCTACAAAGCGGTTTTACTTGCTGCCGCTGCCCTACCCAAGTTTTTCCCAATGTTAACCACA
GCCGCTGGCACCATTCGTCCAGCTAAGGTGTTTGTGATTGGAGCTGGGGTAGCGGGTCTCCAGGCGATCGCCACAGCCAG
AAGACTCGGCGCGGTAGTCGAGGCCTTTGACATCCGGCCCGCCGTCAAAGAAGAAGTCCAAAGTCTCGGCGCTAAATTTG
TCGAAGTGCAACTAGAAGAAGAAACTGCAACGGCCGGTGGCTACGCCAAGGAAGTTTCCGAAGACTCGAAAAAGAAAAGC
CAAGCCCTCATTTCAGACCATGTGGCCACCGCCGATGTGGTGATCACCACCGCCCAAGTTCCCGGTCGCCGCGCCCCCGT
ACTTGTAACCGATGACATGATTGCCCGGATGCAAACCGGATCGGTTTTGATCGATCTCGCCGGCGAACAAGGGGGTAACT
GTGAAGGCTGTGAGGCAGGCCGCGAAGTCCAAGTCCACGGGGCCACGATCATTGCTCCCATTAATCTTCCTTCCACGGTG
CCTGTCCATGCGAGCCAAATGTTTGCCAAGAATATGGCGACCTTGCTACAACTGCTCATTCCCGAAGACGCGATTAATCT
CGATTTTGCCGATGACATCCTAGATTCCGTTTGTGTGACCCATCAAGGGGAAATTCGCAATCAACGGGTCAAAGACGCCC
TGCAACAAATGGCTGTCACTGCCTAA

Upstream 100 bases:

>100_bases
TATGGGGATGGCCGACGGCCCTGGGTTCTCAAGGTTTTGCCACTGAATTGCTCTACATCTACCGTTCAGTCTGTTGCTAT
TGTTTCGTTAAGGAGTTTCT

Downstream 100 bases:

>100_bases
GAAACAGACATTTTCTCAGTTTTGAACCTAAATTTATTCATCTTATCTAAAGGAGTTTTGACTGTTCATGACAACAGCAA
CACTGCTCAGTAGCCTATTC

Product: nicotinamide nucleotide transhydrogenase, chain alpha, part 1

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha; Pyridine nucleotide transhydrogenase subunit alpha [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKIAVARETVAGERRVALTPDQVSRLVKKGWEIHVEAGAGEASLLPDAAYEEAGAKVVGDRQSLWKEADLLVKVAVPTEE
EVALLPEGSMVASLLNPLGQPEIIQKLADKKITALGMELIPRTSRAQSMDVLSSQAGVAGYKAVLLAAAALPKFFPMLTT
AAGTIRPAKVFVIGAGVAGLQAIATARRLGAVVEAFDIRPAVKEEVQSLGAKFVEVQLEEETATAGGYAKEVSEDSKKKS
QALISDHVATADVVITTAQVPGRRAPVLVTDDMIARMQTGSVLIDLAGEQGGNCEGCEAGREVQVHGATIIAPINLPSTV
PVHASQMFAKNMATLLQLLIPEDAINLDFADDILDSVCVTHQGEIRNQRVKDALQQMAVTA

Sequences:

>Translated_381_residues
MKIAVARETVAGERRVALTPDQVSRLVKKGWEIHVEAGAGEASLLPDAAYEEAGAKVVGDRQSLWKEADLLVKVAVPTEE
EVALLPEGSMVASLLNPLGQPEIIQKLADKKITALGMELIPRTSRAQSMDVLSSQAGVAGYKAVLLAAAALPKFFPMLTT
AAGTIRPAKVFVIGAGVAGLQAIATARRLGAVVEAFDIRPAVKEEVQSLGAKFVEVQLEEETATAGGYAKEVSEDSKKKS
QALISDHVATADVVITTAQVPGRRAPVLVTDDMIARMQTGSVLIDLAGEQGGNCEGCEAGREVQVHGATIIAPINLPSTV
PVHASQMFAKNMATLLQLLIPEDAINLDFADDILDSVCVTHQGEIRNQRVKDALQQMAVTA
>Mature_381_residues
MKIAVARETVAGERRVALTPDQVSRLVKKGWEIHVEAGAGEASLLPDAAYEEAGAKVVGDRQSLWKEADLLVKVAVPTEE
EVALLPEGSMVASLLNPLGQPEIIQKLADKKITALGMELIPRTSRAQSMDVLSSQAGVAGYKAVLLAAAALPKFFPMLTT
AAGTIRPAKVFVIGAGVAGLQAIATARRLGAVVEAFDIRPAVKEEVQSLGAKFVEVQLEEETATAGGYAKEVSEDSKKKS
QALISDHVATADVVITTAQVPGRRAPVLVTDDMIARMQTGSVLIDLAGEQGGNCEGCEAGREVQVHGATIIAPINLPSTV
PVHASQMFAKNMATLLQLLIPEDAINLDFADDILDSVCVTHQGEIRNQRVKDALQQMAVTA

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=361, Percent_Identity=40.9972299168975, Blast_Score=262, Evalue=5e-70,
Organism=Homo sapiens, GI122939153, Length=361, Percent_Identity=40.9972299168975, Blast_Score=262, Evalue=5e-70,
Organism=Escherichia coli, GI1787887, Length=368, Percent_Identity=43.2065217391304, Blast_Score=305, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17550456, Length=366, Percent_Identity=39.8907103825137, Blast_Score=272, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR016040
- InterPro:   IPR004571 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 40191; Mature: 40191

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVARETVAGERRVALTPDQVSRLVKKGWEIHVEAGAGEASLLPDAAYEEAGAKVVGD
CEEEEEHHHHCCCCEEEECHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHCCCEEECC
RQSLWKEADLLVKVAVPTEEEVALLPEGSMVASLLNPLGQPEIIQKLADKKITALGMELI
HHHHHHHCCEEEEEECCCCCCEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
PRTSRAQSMDVLSSQAGVAGYKAVLLAAAALPKFFPMLTTAAGTIRPAKVFVIGAGVAGL
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHH
QAIATARRLGAVVEAFDIRPAVKEEVQSLGAKFVEVQLEEETATAGGYAKEVSEDSKKKS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHH
QALISDHVATADVVITTAQVPGRRAPVLVTDDMIARMQTGSVLIDLAGEQGGNCEGCEAG
HHHHHHCCCEEEEEEEEECCCCCCCCEEEEHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
REVQVHGATIIAPINLPSTVPVHASQMFAKNMATLLQLLIPEDAINLDFADDILDSVCVT
CEEEEECEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
HQGEIRNQRVKDALQQMAVTA
CCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIAVARETVAGERRVALTPDQVSRLVKKGWEIHVEAGAGEASLLPDAAYEEAGAKVVGD
CEEEEEHHHHCCCCEEEECHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHCCCEEECC
RQSLWKEADLLVKVAVPTEEEVALLPEGSMVASLLNPLGQPEIIQKLADKKITALGMELI
HHHHHHHCCEEEEEECCCCCCEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
PRTSRAQSMDVLSSQAGVAGYKAVLLAAAALPKFFPMLTTAAGTIRPAKVFVIGAGVAGL
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHH
QAIATARRLGAVVEAFDIRPAVKEEVQSLGAKFVEVQLEEETATAGGYAKEVSEDSKKKS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHH
QALISDHVATADVVITTAQVPGRRAPVLVTDDMIARMQTGSVLIDLAGEQGGNCEGCEAG
HHHHHHCCCEEEEEEEEECCCCCCCCEEEEHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
REVQVHGATIIAPINLPSTVPVHASQMFAKNMATLLQLLIPEDAINLDFADDILDSVCVT
CEEEEECEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
HQGEIRNQRVKDALQQMAVTA
CCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]