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The map label for this gene is lacF [H]

Identifier: 170076766

GI number: 170076766

Start: 132167

End: 133045

Strand: Direct

Name: lacF [H]

Synonym: SYNPCC7002_A0133

Alternate gene names: 170076766

Gene position: 132167-133045 (Clockwise)

Preceding gene: 170076762

Following gene: 170076768

Centisome position: 4.39

GC content: 47.44

Gene sequence:

>879_bases
ATGAAACTTTCAACTAAGTTCCTGACGCCATATCTTTTTCTGTTACCGGCCCTTGCCATTTTGGGCTTAGCGGTCGCCCT
CCCAGCTCTCCAAGCGTTTTACCTCAGTTTCACCGAGTACCAATACGACCTGACCCAAACGCCCCGTTGGATCGGCTTTA
AAAATTTTGCCCTGCTGCTCCAGGACGATCTATTTTGGAAAACCTTGGGTAATACGGTGTTGTATCTGATTGGGGTCGTA
CCGATACTAGTGAGTTTTTCCTTAGCCTTGGCCATTTTGGTGAACCAGAGTCTCCGGGGAATTACTTGGTTTCGGGCGGC
TTTTTATACCCCAGTGATCGTTTCTCTGGTGGTGGCGGGGATTGCCTGGCGCGCCCTGTATGCCTCCAATGGTTTTTTTA
ATCAACTTCTGAAGCAAGTCGGTTTAGGGGATGGGATTCCTTGGCTGACGGATCCAAAACTCGCCCTCTGGAGTGTGATG
TTGGTTACCATTTGGAAAGGGTTAGGCTATTACATGGTGATCTATCTAGCGGGGTTGCAGGCGATTTCTCCGGAACTGTA
TGAAGCAGCTTCCCTAGACGGTTCAGACGGTTGGCGCAAACATCTAGACATTACAGTGCCCTTGATGCGTCCTTACATTT
TGCTAGTGTCTGTGATTTCGGCGATTTCGGCGACAAAAGTCTTTGAAGAAATTTATGTGATGACCCAGGGGGGGCCGTTA
AACGCTTCAAAAACGGTGGTCTATTACCTCTATGAGCAGGCGTTTCAAAATTTAGAGATCAGCTATGCTTGCACCATTGG
CCTAGTCTTGTTCCTGGTAATTTTTGTGCTCTCCATTTTTAATCTTTATCTGTCTCGCCAAACCAATCAAGGCTTTTAG

Upstream 100 bases:

>100_bases
TCTCCTTGGTTCAGGAGCTGGCCCCAAATCACCGTCTAGGTCAGGCAACCTTGGATTTTTGCCTTAAGATACATTTTGAT
TCTGCGCCCCAGTATTCCCC

Downstream 100 bases:

>100_bases
CTTCCCTTAACGGCGCTTGAGTTTGCCCTTGATGCGCTGCCAAAAAATTTCGAGTTCTGGCAGTTTCAACAAACTCGCGA
GGCCGAAGAAAACGGCTAAA

Product: ABC transporter, permease subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKLSTKFLTPYLFLLPALAILGLAVALPALQAFYLSFTEYQYDLTQTPRWIGFKNFALLLQDDLFWKTLGNTVLYLIGVV
PILVSFSLALAILVNQSLRGITWFRAAFYTPVIVSLVVAGIAWRALYASNGFFNQLLKQVGLGDGIPWLTDPKLALWSVM
LVTIWKGLGYYMVIYLAGLQAISPELYEAASLDGSDGWRKHLDITVPLMRPYILLVSVISAISATKVFEEIYVMTQGGPL
NASKTVVYYLYEQAFQNLEISYACTIGLVLFLVIFVLSIFNLYLSRQTNQGF

Sequences:

>Translated_292_residues
MKLSTKFLTPYLFLLPALAILGLAVALPALQAFYLSFTEYQYDLTQTPRWIGFKNFALLLQDDLFWKTLGNTVLYLIGVV
PILVSFSLALAILVNQSLRGITWFRAAFYTPVIVSLVVAGIAWRALYASNGFFNQLLKQVGLGDGIPWLTDPKLALWSVM
LVTIWKGLGYYMVIYLAGLQAISPELYEAASLDGSDGWRKHLDITVPLMRPYILLVSVISAISATKVFEEIYVMTQGGPL
NASKTVVYYLYEQAFQNLEISYACTIGLVLFLVIFVLSIFNLYLSRQTNQGF
>Mature_292_residues
MKLSTKFLTPYLFLLPALAILGLAVALPALQAFYLSFTEYQYDLTQTPRWIGFKNFALLLQDDLFWKTLGNTVLYLIGVV
PILVSFSLALAILVNQSLRGITWFRAAFYTPVIVSLVVAGIAWRALYASNGFFNQLLKQVGLGDGIPWLTDPKLALWSVM
LVTIWKGLGYYMVIYLAGLQAISPELYEAASLDGSDGWRKHLDITVPLMRPYILLVSVISAISATKVFEEIYVMTQGGPL
NASKTVVYYLYEQAFQNLEISYACTIGLVLFLVIFVLSIFNLYLSRQTNQGF

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787570, Length=258, Percent_Identity=29.0697674418605, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789861, Length=280, Percent_Identity=28.2142857142857, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790465, Length=252, Percent_Identity=27.3809523809524, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32722; Mature: 32722

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSTKFLTPYLFLLPALAILGLAVALPALQAFYLSFTEYQYDLTQTPRWIGFKNFALLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHH
QDDLFWKTLGNTVLYLIGVVPILVSFSLALAILVNQSLRGITWFRAAFYTPVIVSLVVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAWRALYASNGFFNQLLKQVGLGDGIPWLTDPKLALWSVMLVTIWKGLGYYMVIYLAGLQ
HHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISPELYEAASLDGSDGWRKHLDITVPLMRPYILLVSVISAISATKVFEEIYVMTQGGPL
HHCHHHHHHHCCCCCCCCHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
NASKTVVYYLYEQAFQNLEISYACTIGLVLFLVIFVLSIFNLYLSRQTNQGF
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLSTKFLTPYLFLLPALAILGLAVALPALQAFYLSFTEYQYDLTQTPRWIGFKNFALLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHH
QDDLFWKTLGNTVLYLIGVVPILVSFSLALAILVNQSLRGITWFRAAFYTPVIVSLVVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAWRALYASNGFFNQLLKQVGLGDGIPWLTDPKLALWSVMLVTIWKGLGYYMVIYLAGLQ
HHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISPELYEAASLDGSDGWRKHLDITVPLMRPYILLVSVISAISATKVFEEIYVMTQGGPL
HHCHHHHHHHCCCCCCCCHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
NASKTVVYYLYEQAFQNLEISYACTIGLVLFLVIFVLSIFNLYLSRQTNQGF
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]