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The map label for this gene is csgA [H]

Identifier: 170076719

GI number: 170076719

Start: 87845

End: 88510

Strand: Direct

Name: csgA [H]

Synonym: SYNPCC7002_A0085

Alternate gene names: 170076719

Gene position: 87845-88510 (Clockwise)

Preceding gene: 170076718

Following gene: 170076721

Centisome position: 2.92

GC content: 50.45

Gene sequence:

>666_bases
ATGTCAACCTATCTCGTTACTGGCGCAAACCGGGGCATCGGCCTGGAATATTGCCGTCAACTCAAAGCCCAAGGCGATCG
CGTGATTGCTGTTTGTCGGACGCCCTCTGAGGAACTGCTGCAACTGGGTGTAACGGTAAAAGCGGATGTGGATCTGACGA
ATCCCGATGCCGTCAAACAGCTTGCCCAAGATCTCCAGGGGGAAACTATTGATGTCTTGATTAACAACGCCGGGATTTTA
GAACGGGTCGATTTAGATCAGCTAGATGTGGACAGTATTCGCCGTCAATTTGAAGTCAATGCGATCGCCCCGCTGCGTTT
CACCCAAGCCCTTTTAGCGAATCTTAAATCTGGTTCAAAAATTATCCTGATGACCAGTCGCATGGGTTCCATTGAAGACA
ATACTTCCGGTGGTTCCTATGGCTATCGAATGTCAAAAGTCGCCCTTTCCATGGCCGGAAAATCCCTGGCGATCGATCTC
AAACCCAGGGGAATTGCGGTGGGTATTTTACACCCTGGCCTCGTGAAAACGCGGATGATTAATTTCCGGGAAGATGGCAT
TAGCCCCACGGTGGCAGTCGAAGGGTTACTGGCCCGCATTGAAGCACTAAATCTCGATAATACAGGCACGTTTTGGCACG
CCAATGGGGAGATTTTGCCCTGGTAA

Upstream 100 bases:

>100_bases
TTTCCCTCGGCTATCTGTAGAGAATCTCGTTTTAAATTTGACTTTCCCAATAGAGCTTGCCACACTGCAAATCGTTGTCT
CAGAACAAATATTCAAGAAT

Downstream 100 bases:

>100_bases
GTGGTGCGTCATTTTTTCTAACTGTAGAGGCTGGCGACGTATTCTCCGTAGCCGTTGTAGGGTAGGGTTTCCTTCATTTC
CCAGCTAAATTCTGGGGTAT

Product: short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSTYLVTGANRGIGLEYCRQLKAQGDRVIAVCRTPSEELLQLGVTVKADVDLTNPDAVKQLAQDLQGETIDVLINNAGIL
ERVDLDQLDVDSIRRQFEVNAIAPLRFTQALLANLKSGSKIILMTSRMGSIEDNTSGGSYGYRMSKVALSMAGKSLAIDL
KPRGIAVGILHPGLVKTRMINFREDGISPTVAVEGLLARIEALNLDNTGTFWHANGEILPW

Sequences:

>Translated_221_residues
MSTYLVTGANRGIGLEYCRQLKAQGDRVIAVCRTPSEELLQLGVTVKADVDLTNPDAVKQLAQDLQGETIDVLINNAGIL
ERVDLDQLDVDSIRRQFEVNAIAPLRFTQALLANLKSGSKIILMTSRMGSIEDNTSGGSYGYRMSKVALSMAGKSLAIDL
KPRGIAVGILHPGLVKTRMINFREDGISPTVAVEGLLARIEALNLDNTGTFWHANGEILPW
>Mature_220_residues
STYLVTGANRGIGLEYCRQLKAQGDRVIAVCRTPSEELLQLGVTVKADVDLTNPDAVKQLAQDLQGETIDVLINNAGILE
RVDLDQLDVDSIRRQFEVNAIAPLRFTQALLANLKSGSKIILMTSRMGSIEDNTSGGSYGYRMSKVALSMAGKSLAIDLK
PRGIAVGILHPGLVKTRMINFREDGISPTVAVEGLLARIEALNLDNTGTFWHANGEILPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Homo sapiens, GI50726952, Length=188, Percent_Identity=32.9787234042553, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786701, Length=186, Percent_Identity=33.8709677419355, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787335, Length=185, Percent_Identity=30.8108108108108, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367365, Length=178, Percent_Identity=28.6516853932584, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17559962, Length=208, Percent_Identity=36.5384615384615, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI72001658, Length=249, Percent_Identity=32.5301204819277, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559964, Length=206, Percent_Identity=35.4368932038835, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17558006, Length=202, Percent_Identity=30.1980198019802, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17558994, Length=245, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17558996, Length=253, Percent_Identity=27.6679841897233, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558992, Length=249, Percent_Identity=31.3253012048193, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532177, Length=204, Percent_Identity=29.9019607843137, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193207563, Length=245, Percent_Identity=26.1224489795918, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17558990, Length=257, Percent_Identity=27.6264591439689, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322779, Length=244, Percent_Identity=26.6393442622951, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640547, Length=252, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24643142, Length=186, Percent_Identity=36.5591397849462, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45554248, Length=198, Percent_Identity=31.3131313131313, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640117, Length=198, Percent_Identity=31.3131313131313, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23976; Mature: 23845

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYLVTGANRGIGLEYCRQLKAQGDRVIAVCRTPSEELLQLGVTVKADVDLTNPDAVKQ
CCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHCCEEEEECCCCCHHHHHH
LAQDLQGETIDVLINNAGILERVDLDQLDVDSIRRQFEVNAIAPLRFTQALLANLKSGSK
HHHHHCCCEEEEEEECCCCEEECCCCCCCHHHHHHHHCCCEECHHHHHHHHHHHCCCCCE
IILMTSRMGSIEDNTSGGSYGYRMSKVALSMAGKSLAIDLKPRGIAVGILHPGLVKTRMI
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCHHHHHEE
NFREDGISPTVAVEGLLARIEALNLDNTGTFWHANGEILPW
EECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCEECC
>Mature Secondary Structure 
STYLVTGANRGIGLEYCRQLKAQGDRVIAVCRTPSEELLQLGVTVKADVDLTNPDAVKQ
CEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHCCEEEEECCCCCHHHHHH
LAQDLQGETIDVLINNAGILERVDLDQLDVDSIRRQFEVNAIAPLRFTQALLANLKSGSK
HHHHHCCCEEEEEEECCCCEEECCCCCCCHHHHHHHHCCCEECHHHHHHHHHHHCCCCCE
IILMTSRMGSIEDNTSGGSYGYRMSKVALSMAGKSLAIDLKPRGIAVGILHPGLVKTRMI
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCHHHHHEE
NFREDGISPTVAVEGLLARIEALNLDNTGTFWHANGEILPW
EECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]