Click here to switch to the map view.

The map label for this gene is ywoG [H]

Identifier: 170076721

GI number: 170076721

Start: 89652

End: 90917

Strand: Direct

Name: ywoG [H]

Synonym: SYNPCC7002_A0087

Alternate gene names: 170076721

Gene position: 89652-90917 (Clockwise)

Preceding gene: 170076719

Following gene: 170076722

Centisome position: 2.98

GC content: 52.21

Gene sequence:

>1266_bases
GTGAAGGTTTTTTTGCAGCTCCAGCCGGAAATGCGCTGGAATTTGGGCTTGTTATTTTTAGCGGCCCTGGGATTTTGGTT
GAGTATGACCAGTTTATTACCGGTGCTCCCGGCCTATATCCAAGATTTGGGGGCAACGGATCAGCAGGTGGGCTTTGTGA
TGGGTTGCTTTGCCATCGGTCTGCTTTTGGCCCGCACCCGCCTCGGTAAAATGGTCGATGAGCAGGGTCGCAAACGGGTA
ATCCTCATTGGCGCTGTGGTGGTGGCGATCGCCCCTTGGGGATATATATTTTTAAATTCAATTCCCCAGATGATGGTGTG
GCGAGCCTTCCATGGAATTAGTATCGCCGCTTTTACGACGGGTTACAGTGCCCTAGTGGTAGATTTGGCCCCAGAACGAA
ACCGGGGTGAGGTGATCAGTTACATGAGTTTGGCGATTCCGGTGGGGATGTCCATTGGGCCAGTGTTGGGGGGTTATCTC
TTGGGGGTCGTCGATTACCCGTGGATCTTTGCGGCGTCGGGTCTGTGTGGGGTGGGGGCTTTGCTCCTGGCCAGTCAAAC
TAAAGAATCTAATCCCCAGGTGATCGCCATTGATAAAAATTCCCTGACGCCCAACCAAGGGGAAACCAACCGTGATTACC
CGGAACTGTTTCGTCATAAGGGACTCTACATTCCTTCCTTGATTATGCTCTGCATTGGCTTGGTATTCGGCGTTTTAGTG
ACGTTTCTCCCCCTGTACATTCGGGAACTGGGCTTAAATTTCAATACCGGACTGTTCTATGGGGCGGCGGCCATTTCTAG
TTTTAGTAGTCGTATCCTCGTGGGTCGGGCGTCGGATACCTTGGGGCGGGGTTTATTTATTAGCGGCAGTCTGCTCTGTT
ACGCCGCAACGATGCTGATCCTCAACCACGCTATCAGTACTCCCTGGTTTGTTGTGGCGGGGGCAGTGGAAGGTTTGGGG
GCAGGGACTCTCGTGCCGATGATGATTGCGCTGATGTCGGATCGTTCTTCTAGTGCGGAACGGGGGAAGGTTTATTCTAT
TTGTATTGGCGGCTTTGATGTGGGGATTGCCCTGGCGGGTCTATTGCTCGGCACCGTCACCCAGACCGTCGGTTATCAAG
GGATTTTTGCGATCGCCGCTGGGTTGGCCCTGTTTTCTTTCTTTATCTTCCTCACCCAAGGCAATGCCAAAATTGGTACT
TCCTTTAAATTTGCCCTTGGGCGCACCGGCGATCGCTATGCCCAAAAATTTTTAAATCAGCCATAG

Upstream 100 bases:

>100_bases
AACGCATTTTGCCAAGGGTCTCCGGCCCCAACTTCGTTAACATCCCTTTACAATTTGAAAAGATATGTCATGTGTTTAAG
CAATTGTTAGGGAAATTTAG

Downstream 100 bases:

>100_bases
TTAGCAATTTTCAAAATGAAACATCCCGAATCTTTTTCCCTGCCTCCCCTTGCCCCCTACGAAGACCGTTTGCTCCATGC
CCTTGCCTTTTTTCGGACGG

Product: major facilitator transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKVFLQLQPEMRWNLGLLFLAALGFWLSMTSLLPVLPAYIQDLGATDQQVGFVMGCFAIGLLLARTRLGKMVDEQGRKRV
ILIGAVVVAIAPWGYIFLNSIPQMMVWRAFHGISIAAFTTGYSALVVDLAPERNRGEVISYMSLAIPVGMSIGPVLGGYL
LGVVDYPWIFAASGLCGVGALLLASQTKESNPQVIAIDKNSLTPNQGETNRDYPELFRHKGLYIPSLIMLCIGLVFGVLV
TFLPLYIRELGLNFNTGLFYGAAAISSFSSRILVGRASDTLGRGLFISGSLLCYAATMLILNHAISTPWFVVAGAVEGLG
AGTLVPMMIALMSDRSSSAERGKVYSICIGGFDVGIALAGLLLGTVTQTVGYQGIFAIAAGLALFSFFIFLTQGNAKIGT
SFKFALGRTGDRYAQKFLNQP

Sequences:

>Translated_421_residues
MKVFLQLQPEMRWNLGLLFLAALGFWLSMTSLLPVLPAYIQDLGATDQQVGFVMGCFAIGLLLARTRLGKMVDEQGRKRV
ILIGAVVVAIAPWGYIFLNSIPQMMVWRAFHGISIAAFTTGYSALVVDLAPERNRGEVISYMSLAIPVGMSIGPVLGGYL
LGVVDYPWIFAASGLCGVGALLLASQTKESNPQVIAIDKNSLTPNQGETNRDYPELFRHKGLYIPSLIMLCIGLVFGVLV
TFLPLYIRELGLNFNTGLFYGAAAISSFSSRILVGRASDTLGRGLFISGSLLCYAATMLILNHAISTPWFVVAGAVEGLG
AGTLVPMMIALMSDRSSSAERGKVYSICIGGFDVGIALAGLLLGTVTQTVGYQGIFAIAAGLALFSFFIFLTQGNAKIGT
SFKFALGRTGDRYAQKFLNQP
>Mature_421_residues
MKVFLQLQPEMRWNLGLLFLAALGFWLSMTSLLPVLPAYIQDLGATDQQVGFVMGCFAIGLLLARTRLGKMVDEQGRKRV
ILIGAVVVAIAPWGYIFLNSIPQMMVWRAFHGISIAAFTTGYSALVVDLAPERNRGEVISYMSLAIPVGMSIGPVLGGYL
LGVVDYPWIFAASGLCGVGALLLASQTKESNPQVIAIDKNSLTPNQGETNRDYPELFRHKGLYIPSLIMLCIGLVFGVLV
TFLPLYIRELGLNFNTGLFYGAAAISSFSSRILVGRASDTLGRGLFISGSLLCYAATMLILNHAISTPWFVVAGAVEGLG
AGTLVPMMIALMSDRSSSAERGKVYSICIGGFDVGIALAGLLLGTVTQTVGYQGIFAIAAGLALFSFFIFLTQGNAKIGT
SFKFALGRTGDRYAQKFLNQP

Specific function: Involved In Sulfonamide (Sulfathiazole) And Bicyclomycin Resistance. Probable Membrane Translocase. [C]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1788509, Length=223, Percent_Identity=26.9058295964126, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45144; Mature: 45144

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFLQLQPEMRWNLGLLFLAALGFWLSMTSLLPVLPAYIQDLGATDQQVGFVMGCFAIG
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LLLARTRLGKMVDEQGRKRVILIGAVVVAIAPWGYIFLNSIPQMMVWRAFHGISIAAFTT
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEECC
GYSALVVDLAPERNRGEVISYMSLAIPVGMSIGPVLGGYLLGVVDYPWIFAASGLCGVGA
CCEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHH
LLLASQTKESNPQVIAIDKNSLTPNQGETNRDYPELFRHKGLYIPSLIMLCIGLVFGVLV
HHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TFLPLYIRELGLNFNTGLFYGAAAISSFSSRILVGRASDTLGRGLFISGSLLCYAATMLI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCEEEEEECCCHHCCCEEECCHHHHHHHHHHH
LNHAISTPWFVVAGAVEGLGAGTLVPMMIALMSDRSSSAERGKVYSICIGGFDVGIALAG
HHHHCCCCCEEEEHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHH
LLLGTVTQTVGYQGIFAIAAGLALFSFFIFLTQGNAKIGTSFKFALGRTGDRYAQKFLNQ
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHCCC
P
C
>Mature Secondary Structure
MKVFLQLQPEMRWNLGLLFLAALGFWLSMTSLLPVLPAYIQDLGATDQQVGFVMGCFAIG
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LLLARTRLGKMVDEQGRKRVILIGAVVVAIAPWGYIFLNSIPQMMVWRAFHGISIAAFTT
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEECC
GYSALVVDLAPERNRGEVISYMSLAIPVGMSIGPVLGGYLLGVVDYPWIFAASGLCGVGA
CCEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHH
LLLASQTKESNPQVIAIDKNSLTPNQGETNRDYPELFRHKGLYIPSLIMLCIGLVFGVLV
HHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TFLPLYIRELGLNFNTGLFYGAAAISSFSSRILVGRASDTLGRGLFISGSLLCYAATMLI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCEEEEEECCCHHCCCEEECCHHHHHHHHHHH
LNHAISTPWFVVAGAVEGLGAGTLVPMMIALMSDRSSSAERGKVYSICIGGFDVGIALAG
HHHHCCCCCEEEEHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHH
LLLGTVTQTVGYQGIFAIAAGLALFSFFIFLTQGNAKIGTSFKFALGRTGDRYAQKFLNQ
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]