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The map label for this gene is fabA [H]

Identifier: 170024859

GI number: 170024859

Start: 2890003

End: 2890629

Strand: Direct

Name: fabA [H]

Synonym: YPK_2634

Alternate gene names: 170024859

Gene position: 2890003-2890629 (Clockwise)

Preceding gene: 170024858

Following gene: 170024861

Centisome position: 61.63

GC content: 47.69

Gene sequence:

>627_bases
ATGGCCATTACGCTGGCTAAACTGGTTCAACCAGGGCTAATCGGACTTGCTCAGCGTACAGCTGTACGCTATTCTGCGCA
CTTCACTAACATAAGGCTTACTGAGAACATGGTAGATAAACGCGAATCCTATACAAAAGAAGACCTTGAAGCATCCGGCC
GTGGCGAGTTGTTTGGCGCTGGTGGGCCACCCTTACCCGCAGGCAATATGTTAATGATGGACCGTATTGTCAAAATGATA
GAAGACGGTGGCAGCCATAATAAAGGTTATGTGGAAGCGGAACTGGATATCAATCCAGATCTATGGTTCTTCGGTTGCCA
TTTTATCGGTGATCCCGTCATGCCTGGCTGTCTGGGCCTTGATGCCATGTGGCAGTTGGTTGGTTTCTATCTCGGCTGGC
TCGGTGGCGAAGGCAAAGGCCGCGCACTGGGTGTTGGTGAAGTTAAATTCACCGGCCAGGTGCTGCCAGATGCGAAAAAA
GTGACATACCGTATTAATTTTAAACGCGTGATTATGCGTAAATTAATTATGGGCGTTGCGGATGGTGAAGTCTTGGTTGA
TGGCAAAGTGATTTACACTGCCACTGATTTGAAAGTAGGTCTGTTTAAAGACACCAACGCTTTCTAA

Upstream 100 bases:

>100_bases
TGACTGGGGTCACTTATGACGATGAGCAGCAACCCAGCCTGTTAGGCGCTATCCAGGAGCGTATCGCACAGATAAACCCA
CAGGATAAACGCCGCTGGCC

Downstream 100 bases:

>100_bases
TACGAATAAGTCAATGCATTGTAAAATAAGGCGAATATGATTAATCATGTCGCCTTATTGTTTTTACGTGATATACCACA
TGAGATTCAGGAGATAGCCT

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MAITLAKLVQPGLIGLAQRTAVRYSAHFTNIRLTENMVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMI
EDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKK
VTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATDLKVGLFKDTNAF

Sequences:

>Translated_208_residues
MAITLAKLVQPGLIGLAQRTAVRYSAHFTNIRLTENMVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMI
EDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKK
VTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATDLKVGLFKDTNAF
>Mature_207_residues
AITLAKLVQPGLIGLAQRTAVRYSAHFTNIRLTENMVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMIE
DGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKKV
TYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATDLKVGLFKDTNAF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=172, Percent_Identity=87.2093023255814, Blast_Score=311, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 22761; Mature: 22630

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITLAKLVQPGLIGLAQRTAVRYSAHFTNIRLTENMVDKRESYTKEDLEASGRGELFGA
CEEEHHHHHCCCHHHHHHHHHEEEEEEEEEEEEHHHHHHHHHHHCHHHHCCCCCCCEEEC
GGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGL
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCHHCH
DAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKKVTYRINFKRVIMRKLIMGVA
HHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCCCCCEEEEEEECHHHHHHHHHHHCCC
DGEVLVDGKVIYTATDLKVGLFKDTNAF
CCCEEECCEEEEEEECEEEEEECCCCCC
>Mature Secondary Structure 
AITLAKLVQPGLIGLAQRTAVRYSAHFTNIRLTENMVDKRESYTKEDLEASGRGELFGA
EEEHHHHHCCCHHHHHHHHHEEEEEEEEEEEEHHHHHHHHHHHCHHHHCCCCCCCEEEC
GGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGL
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCHHCH
DAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKKVTYRINFKRVIMRKLIMGVA
HHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCCCCCEEEEEEECHHHHHHHHHHHCCC
DGEVLVDGKVIYTATDLKVGLFKDTNAF
CCCEEECCEEEEEEECEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA