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The map label for this gene is yheS [H]

Identifier: 170022525

GI number: 170022525

Start: 303776

End: 305698

Strand: Reverse

Name: yheS [H]

Synonym: YPK_0264

Alternate gene names: 170022525

Gene position: 305698-303776 (Counterclockwise)

Preceding gene: 170022530

Following gene: 170022524

Centisome position: 6.52

GC content: 51.17

Gene sequence:

>1923_bases
ATGATTGTTTTTTCCTCGCTTCAAATTCGACGTGGTACTCGCGTCTTGCTGGACAACGCCACAGCTACGATTAACCCCGG
TCAGAAAGTCGGCCTGGTTGGCAAGAACGGTTGTGGTAAATCGACTCTGCTGGCGTTGCTCAAAGGCGAACTGAGCGCCG
ATGGGGGCAATGTCACATTTCCCAATAACTGGGCACTGGCCTGGGTTAATCAGGAAACCCCGGCACTGGATATCCCGGCG
ATAGAGTATGTTATCGACGGTGACCGCGAATATCGCCAGTTGGAGGCCGAACTTCAGGCTGCCAATGAAAAAAATGATGG
CCATGCCATCGCAACCGTGCACGGTAAGCTGGATGCCATCCATGCCTGGACTATCCAATCGCGTGCGGCCAGTTTGCTCC
ACGGGCTCGGGTTTTCTCAAGAAAAACTACAGCAACCGGTACGTTCATTTTCGGGTGGCTGGCGTATGCGTCTTAATCTG
GCGCAGGCGCTGGTTTGCCGCTCTGATTTACTGCTCTTGGATGAACCAACCAACCACTTGGATTTGGATGCCGTCATCTG
GCTGGAAAAATGGCTGAAAAGCTACACCGGTACCTTGGTGTTAATTTCCCATGACCGCGATTTCCTTGATCCTATTATCG
ATAAGATTTTGCATATTGAACAGCAAACGCTGAATGAATATACCGGTAACTATTCATCGTTCGAACGCCAGCGCGCCACC
AAACTGTCGCAACAACAATCGATGTATCAGCATCAGCAAGAAAAAGTGGCGCATTTACAAAGTTATATTGATCGCTTCCG
GGCGCAAGCCACCAAAGCCAAGCAAGCCCAGAGCCGTATCAAGATGCTCGAGCGTATGGAGCTGATTGCCCCTGCACATG
TGGATAATCCGTTCCACTTCAGTTTTCGTACACCAGAAAGCCTGCCAGATCCCTTGCTGCGCATGGATAAAGTCAGTGCC
GGTTACGGGGAAAACACCGTCTTACAGTCCATTAAACTCAACCTGGTGCCCGGTTCACGCATCGGTCTCTTGGGGCGTAA
TGGTGCCGGTAAATCAACGCTGATTAAATTATTGGCCGGGACGTTAGAACCGCAAAGCGGTGAGATCGCCCTGTCCAAAG
GCATTAAACTCGGTTACTTCGCCCAGCATCAGTTGGAGTTCTTACGGGCTGATGAATCACCGTTGCAGCATATGAGCCGC
CTGGCCCCTAAAGAGTCAGAGCAGCAATTGCGCGATTATCTCGGTGGTTACGGCTTTCAGGGCGATCAGGTGACCGACCC
AACCGCCCGCTTCTCCGGTGGAGAGAAGGCGCGTTTAGTGCTGGCACTGATTATTTGGCAACGGCCGAATCTGTTACTGC
TGGATGAGCCCACCAACCATTTGGATTTGGAAATGCGACAAGCCCTGACCGAGGCTCTGATTGATTTTGAAGGCGCATTG
GTGGTGATTTCCCATGACCGTCATTTACTGCGCTCTACCACCGATGACCTCTATCTGGTGCACGACGGTAAAGTGGAACA
GTTCGATGGCGATCTGGAAGATTATCAGCAGTGGCTGGTGGATTCACAGCGCCAGCAAAGCCAACAGGATAATCCGGCGA
AGGAGCTATCGGGCAACAGCGCACAACAGCGTAAAGACCAAAAACGTCGCGATGCTGAATTCCGCACTCAAACGCAGCCA
CTGCGTAAGCAGATTATGACGCTGGAAAAACAGATGGATAAACTCAGCACTGAGCTGGCCGCTATCGAAGCACAGTTGGC
GGATTCAGCACTGTATGATATTGCGCGCAAAGCGGACTTGACCCAATGCCTACTGCAACAAACGCAAGTGAAATCCAAGC
TGGAAGAGACGGAAATGCAGTGGTTAGATGTGCAAGAACAGCTTGAAATACTGACTAAAGAGTTTAGCGATGCCGATATA
TAA

Upstream 100 bases:

>100_bases
TACTCAAGTCAGTCATTAGGATGAGTGAACGTGGCTAACCCCTGTAACTTCAAGTGCAAAGGGGATGATAATTTAACATA
TCCTAAACATGCGGCACTCT

Downstream 100 bases:

>100_bases
TATCGGAAATATAGATATAACATCGCGAATGTAAATATGGCATCGTGAATATAGTCGTGCGAATTGAGTTAGAGTCGCAC
GACTAGAGCGGCGTGATTTT

Product: putative ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTFPNNWALAWVNQETPALDIPA
IEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAIHAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNL
AQALVCRSDLLLLDEPTNHLDLDAVIWLEKWLKSYTGTLVLISHDRDFLDPIIDKILHIEQQTLNEYTGNYSSFERQRAT
KLSQQQSMYQHQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRTPESLPDPLLRMDKVSA
GYGENTVLQSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGTLEPQSGEIALSKGIKLGYFAQHQLEFLRADESPLQHMSR
LAPKESEQQLRDYLGGYGFQGDQVTDPTARFSGGEKARLVLALIIWQRPNLLLLDEPTNHLDLEMRQALTEALIDFEGAL
VVISHDRHLLRSTTDDLYLVHDGKVEQFDGDLEDYQQWLVDSQRQQSQQDNPAKELSGNSAQQRKDQKRRDAEFRTQTQP
LRKQIMTLEKQMDKLSTELAAIEAQLADSALYDIARKADLTQCLLQQTQVKSKLEETEMQWLDVQEQLEILTKEFSDADI

Sequences:

>Translated_640_residues
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTFPNNWALAWVNQETPALDIPA
IEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAIHAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNL
AQALVCRSDLLLLDEPTNHLDLDAVIWLEKWLKSYTGTLVLISHDRDFLDPIIDKILHIEQQTLNEYTGNYSSFERQRAT
KLSQQQSMYQHQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRTPESLPDPLLRMDKVSA
GYGENTVLQSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGTLEPQSGEIALSKGIKLGYFAQHQLEFLRADESPLQHMSR
LAPKESEQQLRDYLGGYGFQGDQVTDPTARFSGGEKARLVLALIIWQRPNLLLLDEPTNHLDLEMRQALTEALIDFEGAL
VVISHDRHLLRSTTDDLYLVHDGKVEQFDGDLEDYQQWLVDSQRQQSQQDNPAKELSGNSAQQRKDQKRRDAEFRTQTQP
LRKQIMTLEKQMDKLSTELAAIEAQLADSALYDIARKADLTQCLLQQTQVKSKLEETEMQWLDVQEQLEILTKEFSDADI
>Mature_640_residues
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTFPNNWALAWVNQETPALDIPA
IEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAIHAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNL
AQALVCRSDLLLLDEPTNHLDLDAVIWLEKWLKSYTGTLVLISHDRDFLDPIIDKILHIEQQTLNEYTGNYSSFERQRAT
KLSQQQSMYQHQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRTPESLPDPLLRMDKVSA
GYGENTVLQSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGTLEPQSGEIALSKGIKLGYFAQHQLEFLRADESPLQHMSR
LAPKESEQQLRDYLGGYGFQGDQVTDPTARFSGGEKARLVLALIIWQRPNLLLLDEPTNHLDLEMRQALTEALIDFEGAL
VVISHDRHLLRSTTDDLYLVHDGKVEQFDGDLEDYQQWLVDSQRQQSQQDNPAKELSGNSAQQRKDQKRRDAEFRTQTQP
LRKQIMTLEKQMDKLSTELAAIEAQLADSALYDIARKADLTQCLLQQTQVKSKLEETEMQWLDVQEQLEILTKEFSDADI

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=537, Percent_Identity=37.6163873370577, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI10947137, Length=527, Percent_Identity=36.2428842504744, Blast_Score=326, Evalue=5e-89,
Organism=Homo sapiens, GI27881506, Length=526, Percent_Identity=35.7414448669202, Blast_Score=325, Evalue=8e-89,
Organism=Homo sapiens, GI69354671, Length=551, Percent_Identity=34.8457350272232, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI10947135, Length=551, Percent_Identity=34.8457350272232, Blast_Score=277, Evalue=2e-74,
Organism=Escherichia coli, GI1789751, Length=629, Percent_Identity=81.2400635930048, Blast_Score=1065, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=527, Percent_Identity=33.7760910815939, Blast_Score=309, Evalue=4e-85,
Organism=Escherichia coli, GI2367384, Length=528, Percent_Identity=31.4393939393939, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1787182, Length=594, Percent_Identity=27.6094276094276, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=33.5078534031414, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87081782, Length=553, Percent_Identity=24.9547920433996, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1787164, Length=215, Percent_Identity=29.7674418604651, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI48994997, Length=249, Percent_Identity=26.5060240963855, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081791, Length=225, Percent_Identity=26.2222222222222, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789672, Length=218, Percent_Identity=26.1467889908257, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081709, Length=225, Percent_Identity=23.5555555555556, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1787547, Length=200, Percent_Identity=25, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787758, Length=208, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1789891, Length=207, Percent_Identity=28.0193236714976, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994883, Length=226, Percent_Identity=25.6637168141593, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786803, Length=218, Percent_Identity=26.605504587156, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788225, Length=209, Percent_Identity=25.3588516746411, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787500, Length=305, Percent_Identity=22.9508196721311, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788506, Length=257, Percent_Identity=25.2918287937743, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786703, Length=213, Percent_Identity=28.6384976525822, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=38.6792452830189, Blast_Score=360, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17555318, Length=540, Percent_Identity=35, Blast_Score=329, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI17559834, Length=548, Percent_Identity=33.5766423357664, Blast_Score=313, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI17511077, Length=278, Percent_Identity=24.4604316546763, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=267, Percent_Identity=25.4681647940075, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=546, Percent_Identity=35.7142857142857, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6320874, Length=529, Percent_Identity=34.9716446124764, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6325030, Length=391, Percent_Identity=30.9462915601023, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324314, Length=400, Percent_Identity=29, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6323278, Length=392, Percent_Identity=28.0612244897959, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24666836, Length=519, Percent_Identity=38.150289017341, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24642252, Length=514, Percent_Identity=39.2996108949416, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI18859989, Length=514, Percent_Identity=39.2996108949416, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24641342, Length=533, Percent_Identity=35.0844277673546, Blast_Score=309, Evalue=3e-84,
Organism=Drosophila melanogaster, GI116007184, Length=200, Percent_Identity=28, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221500365, Length=200, Percent_Identity=28, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574259, Length=246, Percent_Identity=26.4227642276423, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 72199; Mature: 72199

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTF
CEEECCEEECCCCEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEC
PNNWALAWVNQETPALDIPAIEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAI
CCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEE
HAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNLAQALVCRSDLLLLDEPTNHL
EEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLKSYTGTLVLISHDRDFLDPIIDKILHIEQQTLNEYTGNYSSFERQRAT
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KLSQQQSMYQHQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
SFRTPESLPDPLLRMDKVSAGYGENTVLQSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAG
EECCCCCCCCHHHHHHHHCCCCCCHHHHHHEEEEECCCCCEEEEECCCCCHHHHHHHHHH
TLEPQSGEIALSKGIKLGYFAQHQLEFLRADESPLQHMSRLAPKESEQQLRDYLGGYGFQ
CCCCCCCCEEEECCCEEEHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCC
GDQVTDPTARFSGGEKARLVLALIIWQRPNLLLLDEPTNHLDLEMRQALTEALIDFEGAL
CCCCCCCHHHCCCCCHHHHHEEEHEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEE
VVISHDRHLLRSTTDDLYLVHDGKVEQFDGDLEDYQQWLVDSQRQQSQQDNPAKELSGNS
EEEECCCHHHHCCCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
AQQRKDQKRRDAEFRTQTQPLRKQIMTLEKQMDKLSTELAAIEAQLADSALYDIARKADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQCLLQQTQVKSKLEETEMQWLDVQEQLEILTKEFSDADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTF
CEEECCEEECCCCEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEC
PNNWALAWVNQETPALDIPAIEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAI
CCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEE
HAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNLAQALVCRSDLLLLDEPTNHL
EEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLKSYTGTLVLISHDRDFLDPIIDKILHIEQQTLNEYTGNYSSFERQRAT
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KLSQQQSMYQHQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
SFRTPESLPDPLLRMDKVSAGYGENTVLQSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAG
EECCCCCCCCHHHHHHHHCCCCCCHHHHHHEEEEECCCCCEEEEECCCCCHHHHHHHHHH
TLEPQSGEIALSKGIKLGYFAQHQLEFLRADESPLQHMSRLAPKESEQQLRDYLGGYGFQ
CCCCCCCCEEEECCCEEEHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCC
GDQVTDPTARFSGGEKARLVLALIIWQRPNLLLLDEPTNHLDLEMRQALTEALIDFEGAL
CCCCCCCHHHCCCCCHHHHHEEEHEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEE
VVISHDRHLLRSTTDDLYLVHDGKVEQFDGDLEDYQQWLVDSQRQQSQQDNPAKELSGNS
EEEECCCHHHHCCCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
AQQRKDQKRRDAEFRTQTQPLRKQIMTLEKQMDKLSTELAAIEAQLADSALYDIARKADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQCLLQQTQVKSKLEETEMQWLDVQEQLEILTKEFSDADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]