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The map label for this gene is femX [H]

Identifier: 169834190

GI number: 169834190

Start: 657025

End: 658245

Strand: Direct

Name: femX [H]

Synonym: SPH_0708

Alternate gene names: 169834190

Gene position: 657025-658245 (Clockwise)

Preceding gene: 169832721

Following gene: 169833676

Centisome position: 29.26

GC content: 35.63

Gene sequence:

>1221_bases
ATGTATCGTTATCAGCTTGGGATACCACTATCAGAGTATGATGGTTTTGTAAAAGAACATCCCATGGTTAATCTATTACA
AAGCAGTGCTTGGGAAAAAGTGAAATCTGATTGGAATCATGAGAGGCTTGGTGTCTATGAAGGGGAGAACTTACTGGCTG
TGGCTAGTATTCTGATAAAATCTCTGCCTTTGGGGTATAAAATGTTTTATATTCCAAGAGGTCCTATATTGGATTACAGG
GATACAGAACTTTTAAAGTTTGTCCTGCAGTCTATTAAGTCTTATGCTCGCAGTAAGAGAGCGGTTTTTGTGACTTTCGA
TCCAAGCATTTGTCTATCTCAACATTTGGTTAATCAAGATAAAAGAGAATATCCTGAAAATCTTGCTATTGTTGAGATTT
TAGGGCAATTAGGAGTGAAGTGGTCTGGGCGGACAATCGAGATGGATGACACCATTCAGCCTCGTATTCAGGCGAAAATA
TATAAGGAAAATTTTGAAGAAGATAAACTTTCTAAATCAACGAGGCAAGCTATCCGAACAGCACGGAACAAAGGGCTTGA
AATTCAATATGGTGGACTGGAACTATTAGATTCATTTTCGGAGTTGATGAAAAAAACTGAGAAGCGCAAAGAGATTCATT
TAAGAAACGAAGCTTATTATAAAAAATTATTAGATAACTTCAAAGAAGACTCCTATATCACGCTAACGAGTTTGGATGTT
TCTAAGCGTTTAAGAGAATTAGAAGAACAATTAGAAAAAAACAGAGTAGTTGCAGAAAAATTTAATGATGCAACCAGGTC
TTCAAAAGTTCAGGAAAATATAAAAGAAAAAGAACGTTTAAAAGAGGAAATAGATTTCTTGCAGGGATATATGAATATGG
GAAAATCAAACATTCCTTTAGCGGCTACTTTGAGTTTGGAATTTGGTAATACCTCTGTCAATCTATATGCTGGTATGGAT
GATGATTTTAAACGTTACAATGCACCAATTTTAACTTGGTATGAAACGGCTCGCTATGCCTTTGAGCGAGGTATGGTGTG
GCAAAATTTAGGTGGTGTTGAAAACTCTCTCAATGGTGGACTTTATCAGTTTAAGGAAAAATTTAATCCAACGATTGAAG
AATATTTGGGTGAATTTACAATGCCCACTCATCCTCTCTATCCTCTGTTAAGACTTGCTCTTGATTTCCGTAAAACATTA
AGAAAAAAACATAGAAAGTAA

Upstream 100 bases:

>100_bases
ATTCTTGGCTTAAAAACATTGATGGAAGTCTATTTTCGCTAGACTTTTTAATCGAAAATAGTAAAATAGTAGAGAGATAC
TAGTTGAAAGAGAGAAAAAT

Downstream 100 bases:

>100_bases
GTATATGGCACTAACTACACTCACGAAAGAAGAGTTTCGTACTTATTCTGATCAGGTTTCTTCTCGTTCCTTTATGCAAT
CGGTCCAGATGGGGGACTTG

Product: MurM

Products: NA

Alternate protein names: Factor essential for expression of methicillin resistance X [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MYRYQLGIPLSEYDGFVKEHPMVNLLQSSAWEKVKSDWNHERLGVYEGENLLAVASILIKSLPLGYKMFYIPRGPILDYR
DTELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKREYPENLAIVEILGQLGVKWSGRTIEMDDTIQPRIQAKI
YKENFEEDKLSKSTRQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKEDSYITLTSLDV
SKRLRELEEQLEKNRVVAEKFNDATRSSKVQENIKEKERLKEEIDFLQGYMNMGKSNIPLAATLSLEFGNTSVNLYAGMD
DDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLYQFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTL
RKKHRK

Sequences:

>Translated_406_residues
MYRYQLGIPLSEYDGFVKEHPMVNLLQSSAWEKVKSDWNHERLGVYEGENLLAVASILIKSLPLGYKMFYIPRGPILDYR
DTELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKREYPENLAIVEILGQLGVKWSGRTIEMDDTIQPRIQAKI
YKENFEEDKLSKSTRQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKEDSYITLTSLDV
SKRLRELEEQLEKNRVVAEKFNDATRSSKVQENIKEKERLKEEIDFLQGYMNMGKSNIPLAATLSLEFGNTSVNLYAGMD
DDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLYQFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTL
RKKHRK
>Mature_406_residues
MYRYQLGIPLSEYDGFVKEHPMVNLLQSSAWEKVKSDWNHERLGVYEGENLLAVASILIKSLPLGYKMFYIPRGPILDYR
DTELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKREYPENLAIVEILGQLGVKWSGRTIEMDDTIQPRIQAKI
YKENFEEDKLSKSTRQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKEDSYITLTSLDV
SKRLRELEEQLEKNRVVAEKFNDATRSSKVQENIKEKERLKEEIDFLQGYMNMGKSNIPLAATLSLEFGNTSVNLYAGMD
DDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGGLYQFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTL
RKKHRK

Specific function: Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (

COG id: COG2348

COG function: function code V; Uncharacterized protein involved in methicillin resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the femABX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR003447 [H]

Pfam domain/function: PF02388 FemAB [H]

EC number: NA

Molecular weight: Translated: 47517; Mature: 47517

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRYQLGIPLSEYDGFVKEHPMVNLLQSSAWEKVKSDWNHERLGVYEGENLLAVASILIK
CCEEEECCCHHHHCCHHHHCHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
SLPLGYKMFYIPRGPILDYRDTELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQD
HCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCH
KREYPENLAIVEILGQLGVKWSGRTIEMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRT
HHHCCCCHHHHHHHHHHCCEECCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
ARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKEDSYITLTSLDV
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHH
SKRLRELEEQLEKNRVVAEKFNDATRSSKVQENIKEKERLKEEIDFLQGYMNMGKSNIPL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AATLSLEFGNTSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGG
EEEEEEEECCCEEEEEECCCHHHHHHCCCEEEHHHHHHHHHHHCCHHHHCCCCCCCCCCC
LYQFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKHRK
HHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYRYQLGIPLSEYDGFVKEHPMVNLLQSSAWEKVKSDWNHERLGVYEGENLLAVASILIK
CCEEEECCCHHHHCCHHHHCHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
SLPLGYKMFYIPRGPILDYRDTELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQD
HCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCH
KREYPENLAIVEILGQLGVKWSGRTIEMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRT
HHHCCCCHHHHHHHHHHCCEECCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
ARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKEDSYITLTSLDV
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHH
SKRLRELEEQLEKNRVVAEKFNDATRSSKVQENIKEKERLKEEIDFLQGYMNMGKSNIPL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AATLSLEFGNTSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLGGVENSLNGG
EEEEEEEECCCEEEEEECCCHHHHHHCCCEEEHHHHHHHHHHHCCHHHHCCCCCCCCCCC
LYQFKEKFNPTIEEYLGEFTMPTHPLYPLLRLALDFRKTLRKKHRK
HHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA