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The map label for this gene is dhaS [H]

Identifier: 169833473

GI number: 169833473

Start: 1199771

End: 1200328

Strand: Direct

Name: dhaS [H]

Synonym: SPH_1293

Alternate gene names: 169833473

Gene position: 1199771-1200328 (Clockwise)

Preceding gene: 169832483

Following gene: 169832984

Centisome position: 53.43

GC content: 34.05

Gene sequence:

>558_bases
ATGAAGGAAGTAAAAGAAAGGCTTCCTATGGCATCATCACTCATTACAAAAAAACGGATTGCCAAGGCATTTAGAGACCT
ATTAGCTACTAGAGAATTTGACAAAATCTCCATTGTAGATATTATGGAATCAGCTGGCATTCGTAGACAGACCTTTTATA
ATCACTTTCTTGACAAATATGAACTGCTAGACTGGATATTTGAAAATGACTTAACCGAGTATATCACCAATAACTTGGAC
TTCATTTCGGGCCAAAAACTATTACAAGAATTATTTTTTTATTTCGAACAAGAGCGTGACTTTTATATTCAACTTTTTGA
TATTCAAGGGCAAAATAACTTCTATGACCACTTTATCAGCTACTGTCGCTTGCTTGTATCAAAAATTTTAAGAGAATACG
GTCAGATTGATATCGATTCATCTGCTTATACTTGCTTTTTGTTAGACTATCATTCACATGCTCTAGCAGAAATCGTGAAG
GCTTATGTCAATAAAAAAAGTTCAGTTCCACAACCAGACTTTCTCATCATGACAATTATTGGAAAGAGACCACAATGA

Upstream 100 bases:

>100_bases
TGTTTTCGCTTTCATTATATATTTTTTATCGCTGGCTGATAAGGGACAGATTCTATTATTTGTCCCCTTTTAAACCCGTT
TCAAACATTTTTTTGGTAAA

Downstream 100 bases:

>100_bases
CATTTATTTCAAATCATAAACAGAAAATTATTTCAAGTTACATTTCGGCAACTGTCAGCAGTCATCCTGAATTAGAAAAA
CACCCAACCTTACCTTTAGT

Product: dihydroxyacetone kinase regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKEVKERLPMASSLITKKRIAKAFRDLLATREFDKISIVDIMESAGIRRQTFYNHFLDKYELLDWIFENDLTEYITNNLD
FISGQKLLQELFFYFEQERDFYIQLFDIQGQNNFYDHFISYCRLLVSKILREYGQIDIDSSAYTCFLLDYHSHALAEIVK
AYVNKKSSVPQPDFLIMTIIGKRPQ

Sequences:

>Translated_185_residues
MKEVKERLPMASSLITKKRIAKAFRDLLATREFDKISIVDIMESAGIRRQTFYNHFLDKYELLDWIFENDLTEYITNNLD
FISGQKLLQELFFYFEQERDFYIQLFDIQGQNNFYDHFISYCRLLVSKILREYGQIDIDSSAYTCFLLDYHSHALAEIVK
AYVNKKSSVPQPDFLIMTIIGKRPQ
>Mature_185_residues
MKEVKERLPMASSLITKKRIAKAFRDLLATREFDKISIVDIMESAGIRRQTFYNHFLDKYELLDWIFENDLTEYITNNLD
FISGQKLLQELFFYFEQERDFYIQLFDIQGQNNFYDHFISYCRLLVSKILREYGQIDIDSSAYTCFLLDYHSHALAEIVK
AYVNKKSSVPQPDFLIMTIIGKRPQ

Specific function: In complex with dhaQ, upon activation by dihydroxyacetone, activates transcription of the dhaKLM operon. Binds the inverted repeat sequence 5'-GGACACATN(6)ATTTGTCC-3' located upstream of and partially overlapping with the -35 promoter sequence of the dhaK

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR012738
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22030; Mature: 22030

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVKERLPMASSLITKKRIAKAFRDLLATREFDKISIVDIMESAGIRRQTFYNHFLDKY
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
ELLDWIFENDLTEYITNNLDFISGQKLLQELFFYFEQERDFYIQLFDIQGQNNFYDHFIS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHH
YCRLLVSKILREYGQIDIDSSAYTCFLLDYHSHALAEIVKAYVNKKSSVPQPDFLIMTII
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
GKRPQ
CCCCC
>Mature Secondary Structure
MKEVKERLPMASSLITKKRIAKAFRDLLATREFDKISIVDIMESAGIRRQTFYNHFLDKY
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
ELLDWIFENDLTEYITNNLDFISGQKLLQELFFYFEQERDFYIQLFDIQGQNNFYDHFIS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHH
YCRLLVSKILREYGQIDIDSSAYTCFLLDYHSHALAEIVKAYVNKKSSVPQPDFLIMTII
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
GKRPQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]