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The map label for this gene is insK [H]

Identifier: 169832483

GI number: 169832483

Start: 1186654

End: 1187322

Strand: Direct

Name: insK [H]

Synonym: SPH_1279

Alternate gene names: 169832483

Gene position: 1186654-1187322 (Clockwise)

Preceding gene: 169832947

Following gene: 169833473

Centisome position: 52.84

GC content: 37.22

Gene sequence:

>669_bases
ATGACCCTAGAATTACGAAATCGTGGCTTCGTAGTGAACCATAAGAAGGTGCAGCGTCTGATGAAAGTACTTGGTTTAAC
GGCTCGAATTCGCCGTAAACGGAAGTATTCTTCATACCAAGGAGAGGTTGGCAAGAAAGCAGATAATCTTATTCAACGTC
AATTTGAAGCAACCAAACCAATGCAAAAGTGCTACACAGATGTGACAGAATTTGCCATTCCAGCAAGCAGCCAAAAGCTT
TATCTATCACCAGTTTTAGATGGCTTTAACAGCGAAATTATCTCCTACAATCTTTCTACTTCGCCGAACTTAGAACAAGT
AAAAACAATGTTGGAACAAGCCTTTACAGAGAACTATTACGAAAATACAATTCTCCATAGTGACCAAGGATGGCAATACC
AACACGATTTCTATCATCATTTTTTAAAGAATAAGGGAATCCAACCATCTATGTCACGTAAGGGAAATAGCCCAGATAAC
GGTATGATGGAATCTTTCTTTGGCATTCTTAAGTCTGAAATGTTTTATGGTTATGAGAATACGTTTCAGTCACTTGAACA
CTTGGAACAAGCTATTGTAGACTATATTGATTACTACAACAACAAACGAATTAAGATAAAACTAAAAGGACTTAGCCCTG
TACAATACAGAACTAAATCCTTTGCTTAA

Upstream 100 bases:

>100_bases
CCACTTAAAACAGCTGGGTCAAAGCGATAAAGATTATGATATTAAAGCTGAAATTCAGTCAATTTATACTGAGCATAAAG
GAAATTACGGCTATCGTCGC

Downstream 100 bases:

>100_bases
ATTAATTGTCTAACTTTTTGGGGTCAGTACAAACAAGCAACTTCTTTTTCTTTATATCTGATACCAGTAAAGTAGCGTGG
AATATCAATTGTTTCTATAT

Product: integrase core subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTLELRNRGFVVNHKKVQRLMKVLGLTARIRRKRKYSSYQGEVGKKADNLIQRQFEATKPMQKCYTDVTEFAIPASSQKL
YLSPVLDGFNSEIISYNLSTSPNLEQVKTMLEQAFTENYYENTILHSDQGWQYQHDFYHHFLKNKGIQPSMSRKGNSPDN
GMMESFFGILKSEMFYGYENTFQSLEHLEQAIVDYIDYYNNKRIKIKLKGLSPVQYRTKSFA

Sequences:

>Translated_222_residues
MTLELRNRGFVVNHKKVQRLMKVLGLTARIRRKRKYSSYQGEVGKKADNLIQRQFEATKPMQKCYTDVTEFAIPASSQKL
YLSPVLDGFNSEIISYNLSTSPNLEQVKTMLEQAFTENYYENTILHSDQGWQYQHDFYHHFLKNKGIQPSMSRKGNSPDN
GMMESFFGILKSEMFYGYENTFQSLEHLEQAIVDYIDYYNNKRIKIKLKGLSPVQYRTKSFA
>Mature_221_residues
TLELRNRGFVVNHKKVQRLMKVLGLTARIRRKRKYSSYQGEVGKKADNLIQRQFEATKPMQKCYTDVTEFAIPASSQKLY
LSPVLDGFNSEIISYNLSTSPNLEQVKTMLEQAFTENYYENTILHSDQGWQYQHDFYHHFLKNKGIQPSMSRKGNSPDNG
MMESFFGILKSEMFYGYENTFQSLEHLEQAIVDYIDYYNNKRIKIKLKGLSPVQYRTKSFA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=193, Percent_Identity=31.0880829015544, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1789981, Length=222, Percent_Identity=53.1531531531532, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI1788405, Length=224, Percent_Identity=32.5892857142857, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1787263, Length=224, Percent_Identity=32.5892857142857, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1786753, Length=224, Percent_Identity=32.5892857142857, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1786570, Length=224, Percent_Identity=32.5892857142857, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1786490, Length=224, Percent_Identity=32.5892857142857, Blast_Score=100, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 26035; Mature: 25904

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLELRNRGFVVNHKKVQRLMKVLGLTARIRRKRKYSSYQGEVGKKADNLIQRQFEATKP
CEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCH
MQKCYTDVTEFAIPASSQKLYLSPVLDGFNSEIISYNLSTSPNLEQVKTMLEQAFTENYY
HHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHH
ENTILHSDQGWQYQHDFYHHFLKNKGIQPSMSRKGNSPDNGMMESFFGILKSEMFYGYEN
HHCEEECCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCHHH
TFQSLEHLEQAIVDYIDYYNNKRIKIKLKGLSPVQYRTKSFA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCC
>Mature Secondary Structure 
TLELRNRGFVVNHKKVQRLMKVLGLTARIRRKRKYSSYQGEVGKKADNLIQRQFEATKP
EEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCH
MQKCYTDVTEFAIPASSQKLYLSPVLDGFNSEIISYNLSTSPNLEQVKTMLEQAFTENYY
HHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHH
ENTILHSDQGWQYQHDFYHHFLKNKGIQPSMSRKGNSPDNGMMESFFGILKSEMFYGYEN
HHCEEECCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCHHH
TFQSLEHLEQAIVDYIDYYNNKRIKIKLKGLSPVQYRTKSFA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]