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The map label for this gene is pyrF

Identifier: 169824420

GI number: 169824420

Start: 785132

End: 785983

Strand: Direct

Name: pyrF

Synonym: FMG_0723

Alternate gene names: 169824420

Gene position: 785132-785983 (Clockwise)

Preceding gene: 169824419

Following gene: 169824421

Centisome position: 43.68

GC content: 28.52

Gene sequence:

>852_bases
ATGATAATAGATAAGCTTTCTAAAAGAATAAACGAAAGATCTATAGTATGTGTAGGCTTAGATACTAGTACAGATTATGT
ACCAGAGAAAATAAAAAAAGGTAAAAAAGTTAGCGAATATTTATTTGAATTTAATAAAGAAATAATAGATAATACAAAAG
ACTTAGTAGCATGTTTCAAAGTTCAAATCGCTTACTACGAAGCACATGGCATAGAAGGATTGATAGCATATAAAAACACT
CTTAAATATCTTAAAGATAATGATTTGATTTCAATAGCCGATGTAAAAAGAGGAGATATAGCAAATACTGCTAAAGAATA
TGCGAAAGCACATTTCGAAGGAGATTTTGAAGCTGATTTTATAACAGTTAATCCATTTATGGGATATGATACATTAGAAC
ATTACTTACCATATCTTGAATCTAAAGAAAAAGGGATATTCGTACTAATGAGAACATCAAATCCTGGTTCAAAAGACATT
CAATATAAGGATTATAAAGGCCAACCATTATATTATGAAATAGGTGATAATTTAAACAAAATTGCTAAGGATTATCTTGG
AGAATGTAATCTAAGTTGTTTAGGATTTGTAGTAGGTGGAACTCAAAGTGAAAATGCAAACAAAATAAGAGAAAGATATC
CAAATATAATGTTTTTAATTCCTGGTTATGGCGCACAAGGGGCAAAACCTGAAGATATCAGAGTTTATCTTGACAATTTT
AAAAAGGGAATTGTTAATTCATCAAGAGGTATAATATTGAATTACAGAAAATTTGATGATGGAGAAGAAAATATAGGTAA
ATATGCTAGAAAAGCTGTAGAAGATATGAGAAAGGATATTTACTGTGAATAA

Upstream 100 bases:

>100_bases
TCTAAATCAAATAACTCTCCATTTATTGGTGAAAAGTTTAAAGGTAGTATTGAAATGACTATTGTTAACGGTGATGTAAA
ATTTGAGAAAGGAGTTAAAA

Downstream 100 bases:

>100_bases
ATATATCGATTCTGAAATATTACTTAATGAAGAAATAAGCGATGGGATTTTCAAATTAGTTTTAAAAGGAAAATTCGAAG
GAAATCCTGGACAATTTTAT

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MIIDKLSKRINERSIVCVGLDTSTDYVPEKIKKGKKVSEYLFEFNKEIIDNTKDLVACFKVQIAYYEAHGIEGLIAYKNT
LKYLKDNDLISIADVKRGDIANTAKEYAKAHFEGDFEADFITVNPFMGYDTLEHYLPYLESKEKGIFVLMRTSNPGSKDI
QYKDYKGQPLYYEIGDNLNKIAKDYLGECNLSCLGFVVGGTQSENANKIRERYPNIMFLIPGYGAQGAKPEDIRVYLDNF
KKGIVNSSRGIILNYRKFDDGEENIGKYARKAVEDMRKDIYCE

Sequences:

>Translated_283_residues
MIIDKLSKRINERSIVCVGLDTSTDYVPEKIKKGKKVSEYLFEFNKEIIDNTKDLVACFKVQIAYYEAHGIEGLIAYKNT
LKYLKDNDLISIADVKRGDIANTAKEYAKAHFEGDFEADFITVNPFMGYDTLEHYLPYLESKEKGIFVLMRTSNPGSKDI
QYKDYKGQPLYYEIGDNLNKIAKDYLGECNLSCLGFVVGGTQSENANKIRERYPNIMFLIPGYGAQGAKPEDIRVYLDNF
KKGIVNSSRGIILNYRKFDDGEENIGKYARKAVEDMRKDIYCE
>Mature_283_residues
MIIDKLSKRINERSIVCVGLDTSTDYVPEKIKKGKKVSEYLFEFNKEIIDNTKDLVACFKVQIAYYEAHGIEGLIAYKNT
LKYLKDNDLISIADVKRGDIANTAKEYAKAHFEGDFEADFITVNPFMGYDTLEHYLPYLESKEKGIFVLMRTSNPGSKDI
QYKDYKGQPLYYEIGDNLNKIAKDYLGECNLSCLGFVVGGTQSENANKIRERYPNIMFLIPGYGAQGAKPEDIRVYLDNF
KKGIVNSSRGIILNYRKFDDGEENIGKYARKAVEDMRKDIYCE

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_FINM2 (B0S1A1)

Other databases:

- EMBL:   AP008971
- RefSeq:   YP_001692031.1
- ProteinModelPortal:   B0S1A1
- SMR:   B0S1A1
- GeneID:   6019903
- GenomeReviews:   AP008971_GR
- KEGG:   fma:FMG_0723
- HOGENOM:   HBG348634
- OMA:   LLCRTSN
- ProtClustDB:   PRK00125
- BioCyc:   FMAG334413:FMG_0723-MONOMER
- HAMAP:   MF_01215
- InterPro:   IPR013785
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR02127

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 32383; Mature: 32383

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 96-96

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIDKLSKRINERSIVCVGLDTSTDYVPEKIKKGKKVSEYLFEFNKEIIDNTKDLVACFK
CCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHH
VQIAYYEAHGIEGLIAYKNTLKYLKDNDLISIADVKRGDIANTAKEYAKAHFEGDFEADF
HEEEEEECCCCCEEEHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEE
ITVNPFMGYDTLEHYLPYLESKEKGIFVLMRTSNPGSKDIQYKDYKGQPLYYEIGDNLNK
EEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEECCCCCCEEEEECCCCHHH
IAKDYLGECNLSCLGFVVGGTQSENANKIRERYPNIMFLIPGYGAQGAKPEDIRVYLDNF
HHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHH
KKGIVNSSRGIILNYRKFDDGEENIGKYARKAVEDMRKDIYCE
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIIDKLSKRINERSIVCVGLDTSTDYVPEKIKKGKKVSEYLFEFNKEIIDNTKDLVACFK
CCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHH
VQIAYYEAHGIEGLIAYKNTLKYLKDNDLISIADVKRGDIANTAKEYAKAHFEGDFEADF
HEEEEEECCCCCEEEHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEE
ITVNPFMGYDTLEHYLPYLESKEKGIFVLMRTSNPGSKDIQYKDYKGQPLYYEIGDNLNK
EEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEECCCCCCEEEEECCCCHHH
IAKDYLGECNLSCLGFVVGGTQSENANKIRERYPNIMFLIPGYGAQGAKPEDIRVYLDNF
HHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHH
KKGIVNSSRGIILNYRKFDDGEENIGKYARKAVEDMRKDIYCE
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA