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The map label for this gene is pyrK [H]

Identifier: 169824421

GI number: 169824421

Start: 785976

End: 786692

Strand: Direct

Name: pyrK [H]

Synonym: FMG_0724

Alternate gene names: 169824421

Gene position: 785976-786692 (Clockwise)

Preceding gene: 169824420

Following gene: 169824422

Centisome position: 43.72

GC content: 32.91

Gene sequence:

>717_bases
GTGAATAAATATATCGATTCTGAAATATTACTTAATGAAGAAATAAGCGATGGGATTTTCAAATTAGTTTTAAAAGGAAA
ATTCGAAGGAAATCCTGGACAATTTTATATGTTGAGAGCATGGGATGAATCGCCGCTTCTTCCCAGACCTTTAAGTATTT
GTGATTTAGATGAAGAAAGTATAACATTTTTATACGCAGTAGTAGGTAGAGGTACATCTATAATCTCATCAATGAGAGTA
GGAGAAAGTATAAAAATTCTTGGGCCTTTAGGAAATGGATTCGAATTACATCCAGAAGCTAAATGTGCTATAGTTGCGGG
TGGAATAGGAATTGCTCCAATGAAATATTTATCAAGAAAACTAAAAAACATTGATTTATACGTAGGATACAGAGACACTT
CATACATGGAAGATGAGATTTTGAATAAAAATAGTACAATTATATCCACGGAGGATGGATCTATTGGGCTCAAAGGATAT
ATAACTGAATATGTTAAAAATGAATACGATTATATTTATGCTTGCGGTCCAAACCCTATGATGAATTCATTGAAAAAAAG
AAATCTGAATGCTATAGAATTTTATTCTTTAGAAGCACACATGGCATGTGGGATAGGGGCGTGTTTAGGGTGTACTGTTC
ATACAACAAGTGGTCTTAAAAGAGTTTGCAAAGATGGCCCTGTTTTTGAAAAAAATGAGGTGATATTTGATGCTTAA

Upstream 100 bases:

>100_bases
AGAGGTATAATATTGAATTACAGAAAATTTGATGATGGAGAAGAAAATATAGGTAAATATGCTAGAAAAGCTGTAGAAGA
TATGAGAAAGGATATTTACT

Downstream 100 bases:

>100_bases
AACGAATTTCTGTGGAGTAGAATTCAAAAATCCTGTTGTTGGAGCTTCTGGTACTTTTGGATTTGGAAGAGAATATGAAA
ATTTTACAGATTTAAATAAA

Product: dihydroorotate dehydrogenase electron transfer subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MNKYIDSEILLNEEISDGIFKLVLKGKFEGNPGQFYMLRAWDESPLLPRPLSICDLDEESITFLYAVVGRGTSIISSMRV
GESIKILGPLGNGFELHPEAKCAIVAGGIGIAPMKYLSRKLKNIDLYVGYRDTSYMEDEILNKNSTIISTEDGSIGLKGY
ITEYVKNEYDYIYACGPNPMMNSLKKRNLNAIEFYSLEAHMACGIGACLGCTVHTTSGLKRVCKDGPVFEKNEVIFDA

Sequences:

>Translated_238_residues
MNKYIDSEILLNEEISDGIFKLVLKGKFEGNPGQFYMLRAWDESPLLPRPLSICDLDEESITFLYAVVGRGTSIISSMRV
GESIKILGPLGNGFELHPEAKCAIVAGGIGIAPMKYLSRKLKNIDLYVGYRDTSYMEDEILNKNSTIISTEDGSIGLKGY
ITEYVKNEYDYIYACGPNPMMNSLKKRNLNAIEFYSLEAHMACGIGACLGCTVHTTSGLKRVCKDGPVFEKNEVIFDA
>Mature_238_residues
MNKYIDSEILLNEEISDGIFKLVLKGKFEGNPGQFYMLRAWDESPLLPRPLSICDLDEESITFLYAVVGRGTSIISSMRV
GESIKILGPLGNGFELHPEAKCAIVAGGIGIAPMKYLSRKLKNIDLYVGYRDTSYMEDEILNKNSTIISTEDGSIGLKGY
ITEYVKNEYDYIYACGPNPMMNSLKKRNLNAIEFYSLEAHMACGIGACLGCTVHTTSGLKRVCKDGPVFEKNEVIFDA

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 26383; Mature: 26383

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYIDSEILLNEEISDGIFKLVLKGKFEGNPGQFYMLRAWDESPLLPRPLSICDLDEES
CCCCCCCCEEECCCHHHHHEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEECCCCHH
ITFLYAVVGRGTSIISSMRVGESIKILGPLGNGFELHPEAKCAIVAGGIGIAPMKYLSRK
HEEEEEECCCCHHHHHHHHCCCEEEEEECCCCCEEECCCCEEEEEECCCCCHHHHHHHHH
LKNIDLYVGYRDTSYMEDEILNKNSTIISTEDGSIGLKGYITEYVKNEYDYIYACGPNPM
HCCEEEEEEECCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCHH
MNSLKKRNLNAIEFYSLEAHMACGIGACLGCTVHTTSGLKRVCKDGPVFEKNEVIFDA
HHHHHHCCCCEEEEEEEEHHHHCCCHHHHCEEEECCHHHHHHHCCCCCCCCCCEEEEC
>Mature Secondary Structure
MNKYIDSEILLNEEISDGIFKLVLKGKFEGNPGQFYMLRAWDESPLLPRPLSICDLDEES
CCCCCCCCEEECCCHHHHHEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEECCCCHH
ITFLYAVVGRGTSIISSMRVGESIKILGPLGNGFELHPEAKCAIVAGGIGIAPMKYLSRK
HEEEEEECCCCHHHHHHHHCCCEEEEEECCCCCEEECCCCEEEEEECCCCCHHHHHHHHH
LKNIDLYVGYRDTSYMEDEILNKNSTIISTEDGSIGLKGYITEYVKNEYDYIYACGPNPM
HCCEEEEEEECCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCHH
MNSLKKRNLNAIEFYSLEAHMACGIGACLGCTVHTTSGLKRVCKDGPVFEKNEVIFDA
HHHHHHCCCCEEEEEEEEHHHHCCCHHHHCEEEECCHHHHHHHCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]