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The map label for this gene is fadE25 [H]

Identifier: 169630697

GI number: 169630697

Start: 3666946

End: 3668109

Strand: Reverse

Name: fadE25 [H]

Synonym: MAB_3618c

Alternate gene names: 169630697

Gene position: 3668109-3666946 (Counterclockwise)

Preceding gene: 169630698

Following gene: 169630693

Centisome position: 72.39

GC content: 64.69

Gene sequence:

>1164_bases
ATGGCTGGGAACCCGTCGTTTGACCTGTTCAAGTTGGGCGAGGAGCACGACGAGCTGCGTGCGGCGATCCGGGGACTGGC
CGAGAAAGAGATCGCACCGCACGCCAAGGACGTCGACGAGAAGGCACGCTTCCCGCAGGAGGCCCTCGACGCGCTGGTCG
CGTCCGGTTTCAATGCCGTGCACGTGCCGGAGGAGTACGACGGTCAGGGTGCCGACAGCGTGGCCGCCTGCATTGTCATC
GAAGAGGTGGCCCGGGTGTGTGCCTCGTCCTCGCTGATCCCTGCCGTCAACAAGCTCGGCACCATGGGGCTGATCCTCAA
CGGCTCCGATGAGCTGAAGAAGCAGGTGCTGCCCGCGATCGCCAGCGGCGAGGCGATGGCCTCCTACGCGCTGTCCGAGC
GGGAGGCCGGAAGTGATGCCGCGAGCATGCGCACCCGCGCGAAGGCCGACGGCGATGACTGGATCATCAACGGGTCCAAG
TGCTGGATCACCAACGGCGGAAAGTCGTCCTGGTACACCGTCATGGCGGTGACCGATCCGGAGAAGAAGGCCAACGGCAT
CTCGGCCTTCATGGTGCACAAGGACGATGAAGGATTCACTGTCGGTCCGCTGGAGCACAAGCTGGGCATCAAGGGCTCGC
CGACCGCGGAGCTGTACTTCGAGAACTGTCGTATCCCGGGCGACCGCATCATCGGCGAACCGGGCACCGGATTCAAGACG
GCGCTTCAGACGCTCGACCACACCCGCCCCACCATCGGGGCCCAGGCGCTCGGCATCGCGCAGGGAGCGTTGGACCAGGC
CATCGCCTACACCAAGGACCGCAAGCAGTTCGGCAAGTCCATCAGCGACTTCCAGGGCGTGCAGTTCATGCTGGCTGACA
TGGCGATGAAGGTCGAGGCCGCGCGCCTCATGGTGTACACCGCCGCCGCCCGCGCCGAGCGCGGCGAGAAGAACCTGGGC
TTCATCTCCTCGGCGTCCAAATGTTTTGCCAGCGATGTGGCCATGGAGGTCACCACCGACGCCGTACAGCTGTTCGGCGG
CGCCGGATACACCACCGATTTTCCGGTGGAGCGCATGATGCGTGATGCCAAGATCACTCAGATCTACGAGGGCACCAACC
AGATCCAGCGCGTCGTCATGAGCCGCGCGCTGCTCACGTCCTAA

Upstream 100 bases:

>100_bases
GGAGAAAGACGAGGCTCTGCGGCGCAGACTGTTGGAGGACTAGATTTGACCGTGACGTACAGTTAATGCCGACTAACTTT
GATCGACTCTGGAGGCTGTG

Downstream 100 bases:

>100_bases
CGCCGAGCATGCCCAAATGTGCCTAAATATGCGGATATTCGGCACATTTGGGCATGTTCACGCGGCGTGATGACGCAGAT
GGGTGTTGATTCGTGCAACA

Product: acyl-CoA dehydrogenase FadE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MAGNPSFDLFKLGEEHDELRAAIRGLAEKEIAPHAKDVDEKARFPQEALDALVASGFNAVHVPEEYDGQGADSVAACIVI
EEVARVCASSSLIPAVNKLGTMGLILNGSDELKKQVLPAIASGEAMASYALSEREAGSDAASMRTRAKADGDDWIINGSK
CWITNGGKSSWYTVMAVTDPEKKANGISAFMVHKDDEGFTVGPLEHKLGIKGSPTAELYFENCRIPGDRIIGEPGTGFKT
ALQTLDHTRPTIGAQALGIAQGALDQAIAYTKDRKQFGKSISDFQGVQFMLADMAMKVEAARLMVYTAAARAERGEKNLG
FISSASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLTS

Sequences:

>Translated_387_residues
MAGNPSFDLFKLGEEHDELRAAIRGLAEKEIAPHAKDVDEKARFPQEALDALVASGFNAVHVPEEYDGQGADSVAACIVI
EEVARVCASSSLIPAVNKLGTMGLILNGSDELKKQVLPAIASGEAMASYALSEREAGSDAASMRTRAKADGDDWIINGSK
CWITNGGKSSWYTVMAVTDPEKKANGISAFMVHKDDEGFTVGPLEHKLGIKGSPTAELYFENCRIPGDRIIGEPGTGFKT
ALQTLDHTRPTIGAQALGIAQGALDQAIAYTKDRKQFGKSISDFQGVQFMLADMAMKVEAARLMVYTAAARAERGEKNLG
FISSASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLTS
>Mature_386_residues
AGNPSFDLFKLGEEHDELRAAIRGLAEKEIAPHAKDVDEKARFPQEALDALVASGFNAVHVPEEYDGQGADSVAACIVIE
EVARVCASSSLIPAVNKLGTMGLILNGSDELKKQVLPAIASGEAMASYALSEREAGSDAASMRTRAKADGDDWIINGSKC
WITNGGKSSWYTVMAVTDPEKKANGISAFMVHKDDEGFTVGPLEHKLGIKGSPTAELYFENCRIPGDRIIGEPGTGFKTA
LQTLDHTRPTIGAQALGIAQGALDQAIAYTKDRKQFGKSISDFQGVQFMLADMAMKVEAARLMVYTAAARAERGEKNLGF
ISSASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLTS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=384, Percent_Identity=45.3125, Blast_Score=315, Evalue=4e-86,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=40.6914893617021, Blast_Score=302, Evalue=3e-82,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=40.6914893617021, Blast_Score=302, Evalue=3e-82,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=38.5026737967914, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI21361497, Length=354, Percent_Identity=37.8531073446328, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=34.6666666666667, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI226958412, Length=383, Percent_Identity=34.7258485639687, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI226958414, Length=347, Percent_Identity=35.7348703170029, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4501857, Length=379, Percent_Identity=33.245382585752, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI4557235, Length=330, Percent_Identity=36.6666666666667, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI76496475, Length=330, Percent_Identity=36.6666666666667, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI4503943, Length=370, Percent_Identity=24.5945945945946, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI48976061, Length=384, Percent_Identity=26.5625, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI211971008, Length=384, Percent_Identity=26.5625, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=24.1573033707865, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI87081958, Length=379, Percent_Identity=31.1345646437995, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1786223, Length=377, Percent_Identity=27.8514588859416, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87081702, Length=381, Percent_Identity=25.9842519685039, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082384, Length=304, Percent_Identity=23.0263157894737, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=42.4802110817942, Blast_Score=317, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=39.5778364116095, Blast_Score=296, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=42.0485175202156, Blast_Score=294, Evalue=6e-80,
Organism=Caenorhabditis elegans, GI17534899, Length=379, Percent_Identity=38.7862796833773, Blast_Score=287, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=38.9041095890411, Blast_Score=273, Evalue=8e-74,
Organism=Caenorhabditis elegans, GI17538396, Length=384, Percent_Identity=36.9791666666667, Blast_Score=258, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=37.466307277628, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI71990804, Length=297, Percent_Identity=41.4141414141414, Blast_Score=224, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI71985184, Length=351, Percent_Identity=36.4672364672365, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI32563615, Length=238, Percent_Identity=42.0168067226891, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71985192, Length=287, Percent_Identity=37.2822299651568, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17505929, Length=381, Percent_Identity=30.4461942257218, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI71982178, Length=279, Percent_Identity=33.3333333333333, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=31.8181818181818, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17531909, Length=236, Percent_Identity=34.7457627118644, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=24.8677248677249, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17531913, Length=171, Percent_Identity=32.1637426900585, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=356, Percent_Identity=26.685393258427, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=304, Percent_Identity=26.9736842105263, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI86563383, Length=304, Percent_Identity=26.9736842105263, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24660351, Length=384, Percent_Identity=39.3229166666667, Blast_Score=294, Evalue=6e-80,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=40.7407407407407, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI24646207, Length=379, Percent_Identity=40.3693931398417, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=36.436170212766, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI21355753, Length=388, Percent_Identity=35.3092783505155, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI281363737, Length=389, Percent_Identity=34.7043701799486, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI19920834, Length=380, Percent_Identity=27.8947368421053, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI45550141, Length=323, Percent_Identity=27.8637770897833, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221473076, Length=323, Percent_Identity=27.8637770897833, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41474; Mature: 41343

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNPSFDLFKLGEEHDELRAAIRGLAEKEIAPHAKDVDEKARFPQEALDALVASGFNAV
CCCCCCCHHEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHCCCCEE
HVPEEYDGQGADSVAACIVIEEVARVCASSSLIPAVNKLGTMGLILNGSDELKKQVLPAI
ECCHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHH
ASGEAMASYALSEREAGSDAASMRTRAKADGDDWIINGSKCWITNGGKSSWYTVMAVTDP
HCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCEEEEEEEECC
EKKANGISAFMVHKDDEGFTVGPLEHKLGIKGSPTAELYFENCRIPGDRIIGEPGTGFKT
HHHCCCCEEEEEEECCCCCEECCHHHHCCCCCCCCCEEEEECCCCCCCCEECCCCCCHHH
ALQTLDHTRPTIGAQALGIAQGALDQAIAYTKDRKQFGKSISDFQGVQFMLADMAMKVEA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ARLMVYTAAARAERGEKNLGFISSASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERMM
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RDAKITQIYEGTNQIQRVVMSRALLTS
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGNPSFDLFKLGEEHDELRAAIRGLAEKEIAPHAKDVDEKARFPQEALDALVASGFNAV
CCCCCCHHEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHCCCCEE
HVPEEYDGQGADSVAACIVIEEVARVCASSSLIPAVNKLGTMGLILNGSDELKKQVLPAI
ECCHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHH
ASGEAMASYALSEREAGSDAASMRTRAKADGDDWIINGSKCWITNGGKSSWYTVMAVTDP
HCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCEEEEEEEECC
EKKANGISAFMVHKDDEGFTVGPLEHKLGIKGSPTAELYFENCRIPGDRIIGEPGTGFKT
HHHCCCCEEEEEEECCCCCEECCHHHHCCCCCCCCCEEEEECCCCCCCCEECCCCCCHHH
ALQTLDHTRPTIGAQALGIAQGALDQAIAYTKDRKQFGKSISDFQGVQFMLADMAMKVEA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ARLMVYTAAARAERGEKNLGFISSASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERMM
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RDAKITQIYEGTNQIQRVVMSRALLTS
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]