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The map label for this gene is fadE25 [H]

Identifier: 169630658

GI number: 169630658

Start: 3623717

End: 3625450

Strand: Reverse

Name: fadE25 [H]

Synonym: MAB_3578c

Alternate gene names: 169630658

Gene position: 3625450-3623717 (Counterclockwise)

Preceding gene: 169630659

Following gene: 169630657

Centisome position: 71.55

GC content: 68.22

Gene sequence:

>1734_bases
GTGACGACATCGATCACGCTCGTGGCACCGCGACGCTTCGACATTGTCGACACGGTCGAGGCCGCGCTGGGCGATGCCCG
CGACCCGGACAACCCGGCTGGTTTCGCAGTGCTGGCGGCACAGGACCGGGACGACACGTTTCCCGCCGACGCCATCGCGA
TCCTTGACCGTCTTCGCGTCGCCGAGCACTACGTGCCGGTGGCCGACGGCGGCCGTCTGGCCGATTATCTTGAGGTATCT
CAGCTCATTCGCGTTCTGGCTCGCCGCAGTGTGACGCTGGCGGTCGCCCACGCCAAGACTTTTCTCGGCGCTGCGACGGC
CTGGATTGGCGCGAGAGGCGAGCAGCGCGCCCGCCTCTCCGAGCTGGTTCGGTCGGGAGTGCCGGTCAGCTGGGGTCTCA
CCGAGCGCGAGCACGGCTCGGACCTGCTCGCCGGAGACGTCGCCGTAGAGAATGGGGCGCTCTCGGGGGCGAAGTGGCTT
ATCAACAACGCCACCCGTGGCGGCGCGGTAGTGGCCATCGCCCGAACTTCCGTGGCCGGCGGACCCCGCGGATTCGATCT
CGTACTGGTCGACAAGGCGGCATTGTCCGCACGGGGAGCGGCACCTACCTATCGGCACCTCCCCAAGGAGCTCACTCACG
GCATCCGCGGTGCGGACATATCCGGTATCGAATTTGACGGGGTACCGGTCGACGACACCGATGTCCTGAGTGAGCCCGGG
CGCGGTCTGGAGAATGTGATGAAGGCGCTGCAGCTGACTCGCACCCTGTGCTGCAGCCTGTCTGTGGGTGCCGCCGAGCG
TGGACTGCACACGGCGGTTTCTTTTGCGGAAAGCCGAGAACTATACGGGCGCAAATTAATCGAGCTACCTCAGGCGCGGC
GGGTGCTCACGGACGCCCTCGCTGATCACCTGCTCAACGAGGTGACCACGTGCGCCGCGATCCGCTCGATCCACACGCTG
CCCGCCGAGTTATCGCTGCATGCCGCCGCGGCGAAGTACTGGGTGCCGACTCGCACCGAGGCGCTGCTGGCCGCGTTGCG
CTCGTTTGTCGGGGCTCGGGCGGTACTCGATTCCGACGACCCGACCGCCCCGGCGCTGAGCCGGATAGAACGCGACCATC
GCATTGTCTCCCTGTTCGACGGGAACACCGTGGTCAACCTCACCACGCTCATCACCCAGTTCCCGGTGATCGGCCGCGGC
GACCTGCCGGCCGACTCCGCGGCACTGGTCGCCGCGGCGCCCGACGCAGACCTGAGCCGGCTGTCACTCATGAGCCGGTC
CGGATCGACGCTGCTGCGTACGCTCGGGGACGCGGTCATCCAGCTCGATGGGCACGACTTGCCCGACGGCTGCCGGCGCA
CGGCGTCGGCGCTCGCCGCCGTCGCCCGGGATATCGTGCGCGCGGCGGCCGATGCGCCTCGTAACCCCGCGGAGACGCCG
AACGCGAGCTTCGCGCTTGCCGAGCGTCTTGCCGCCGCGATCGCCGGTGCCGCGGCGGTGCATGTCTATCTCGCCTACGC
GGGGACCATCGATTCACCGCTGTGGCGGGACGGTCTGTGGTTGCGTCTGGCGCTGCCGCGGGCACTTGCCGGTGCGGATC
CCGCGGCTCCGCCGTCCGGACCCGACGGCGACCACGATGCCGCCATTGCGGCACTCGAATCGCTGAATCGCTCGGATGCG
GGTTTCAGCGTGCTGGCGAACGTGCTCGATGACGAGACGGGAGATCGAGTATGA

Upstream 100 bases:

>100_bases
GCAAGATCCGTAGAACCCATATGCGAGCCTCCTATGAGGGGGGCCGGATCACGGCGTTCGCGGATCCGCGGCTGGCCTCC
GCCGGCGGGGACGTCGTCCG

Downstream 100 bases:

>100_bases
CCACGGCGATATCCACTACGGCAACCGATCTGGACGTGGCCCTGGGTGATCCCTTCTGCCCGGCCAACCCGCACGGTGCC
ACTGCGATTCTGGCGGCGGA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 576

Protein sequence:

>577_residues
MTTSITLVAPRRFDIVDTVEAALGDARDPDNPAGFAVLAAQDRDDTFPADAIAILDRLRVAEHYVPVADGGRLADYLEVS
QLIRVLARRSVTLAVAHAKTFLGAATAWIGARGEQRARLSELVRSGVPVSWGLTEREHGSDLLAGDVAVENGALSGAKWL
INNATRGGAVVAIARTSVAGGPRGFDLVLVDKAALSARGAAPTYRHLPKELTHGIRGADISGIEFDGVPVDDTDVLSEPG
RGLENVMKALQLTRTLCCSLSVGAAERGLHTAVSFAESRELYGRKLIELPQARRVLTDALADHLLNEVTTCAAIRSIHTL
PAELSLHAAAAKYWVPTRTEALLAALRSFVGARAVLDSDDPTAPALSRIERDHRIVSLFDGNTVVNLTTLITQFPVIGRG
DLPADSAALVAAAPDADLSRLSLMSRSGSTLLRTLGDAVIQLDGHDLPDGCRRTASALAAVARDIVRAAADAPRNPAETP
NASFALAERLAAAIAGAAAVHVYLAYAGTIDSPLWRDGLWLRLALPRALAGADPAAPPSGPDGDHDAAIAALESLNRSDA
GFSVLANVLDDETGDRV

Sequences:

>Translated_577_residues
MTTSITLVAPRRFDIVDTVEAALGDARDPDNPAGFAVLAAQDRDDTFPADAIAILDRLRVAEHYVPVADGGRLADYLEVS
QLIRVLARRSVTLAVAHAKTFLGAATAWIGARGEQRARLSELVRSGVPVSWGLTEREHGSDLLAGDVAVENGALSGAKWL
INNATRGGAVVAIARTSVAGGPRGFDLVLVDKAALSARGAAPTYRHLPKELTHGIRGADISGIEFDGVPVDDTDVLSEPG
RGLENVMKALQLTRTLCCSLSVGAAERGLHTAVSFAESRELYGRKLIELPQARRVLTDALADHLLNEVTTCAAIRSIHTL
PAELSLHAAAAKYWVPTRTEALLAALRSFVGARAVLDSDDPTAPALSRIERDHRIVSLFDGNTVVNLTTLITQFPVIGRG
DLPADSAALVAAAPDADLSRLSLMSRSGSTLLRTLGDAVIQLDGHDLPDGCRRTASALAAVARDIVRAAADAPRNPAETP
NASFALAERLAAAIAGAAAVHVYLAYAGTIDSPLWRDGLWLRLALPRALAGADPAAPPSGPDGDHDAAIAALESLNRSDA
GFSVLANVLDDETGDRV
>Mature_576_residues
TTSITLVAPRRFDIVDTVEAALGDARDPDNPAGFAVLAAQDRDDTFPADAIAILDRLRVAEHYVPVADGGRLADYLEVSQ
LIRVLARRSVTLAVAHAKTFLGAATAWIGARGEQRARLSELVRSGVPVSWGLTEREHGSDLLAGDVAVENGALSGAKWLI
NNATRGGAVVAIARTSVAGGPRGFDLVLVDKAALSARGAAPTYRHLPKELTHGIRGADISGIEFDGVPVDDTDVLSEPGR
GLENVMKALQLTRTLCCSLSVGAAERGLHTAVSFAESRELYGRKLIELPQARRVLTDALADHLLNEVTTCAAIRSIHTLP
AELSLHAAAAKYWVPTRTEALLAALRSFVGARAVLDSDDPTAPALSRIERDHRIVSLFDGNTVVNLTTLITQFPVIGRGD
LPADSAALVAAAPDADLSRLSLMSRSGSTLLRTLGDAVIQLDGHDLPDGCRRTASALAAVARDIVRAAADAPRNPAETPN
ASFALAERLAAAIAGAAAVHVYLAYAGTIDSPLWRDGLWLRLALPRALAGADPAAPPSGPDGDHDAAIAALESLNRSDAG
FSVLANVLDDETGDRV

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=300, Percent_Identity=26.3333333333333, Blast_Score=76, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 60502; Mature: 60371

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSITLVAPRRFDIVDTVEAALGDARDPDNPAGFAVLAAQDRDDTFPADAIAILDRLRV
CCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
AEHYVPVADGGRLADYLEVSQLIRVLARRSVTLAVAHAKTFLGAATAWIGARGEQRARLS
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHH
ELVRSGVPVSWGLTEREHGSDLLAGDVAVENGALSGAKWLINNATRGGAVVAIARTSVAG
HHHHCCCCCEECCCCCCCCCCEEECCEEECCCCCCCHHHHCCCCCCCCEEEEEEEECCCC
GPRGFDLVLVDKAALSARGAAPTYRHLPKELTHGIRGADISGIEFDGVPVDDTDVLSEPG
CCCCEEEEEEEHHHHHCCCCCCHHHHCHHHHHCCCCCCCCCCEEECCCCCCCHHHHCCCC
RGLENVMKALQLTRTLCCSLSVGAAERGLHTAVSFAESRELYGRKLIELPQARRVLTDAL
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
ADHLLNEVTTCAAIRSIHTLPAELSLHAAAAKYWVPTRTEALLAALRSFVGARAVLDSDD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCCC
PTAPALSRIERDHRIVSLFDGNTVVNLTTLITQFPVIGRGDLPADSAALVAAAPDADLSR
CCHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHH
LSLMSRSGSTLLRTLGDAVIQLDGHDLPDGCRRTASALAAVARDIVRAAADAPRNPAETP
HHHHHCCCHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NASFALAERLAAAIAGAAAVHVYLAYAGTIDSPLWRDGLWLRLALPRALAGADPAAPPSG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHCCCCCCCCCCC
PDGDHDAAIAALESLNRSDAGFSVLANVLDDETGDRV
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTSITLVAPRRFDIVDTVEAALGDARDPDNPAGFAVLAAQDRDDTFPADAIAILDRLRV
CCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
AEHYVPVADGGRLADYLEVSQLIRVLARRSVTLAVAHAKTFLGAATAWIGARGEQRARLS
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHH
ELVRSGVPVSWGLTEREHGSDLLAGDVAVENGALSGAKWLINNATRGGAVVAIARTSVAG
HHHHCCCCCEECCCCCCCCCCEEECCEEECCCCCCCHHHHCCCCCCCCEEEEEEEECCCC
GPRGFDLVLVDKAALSARGAAPTYRHLPKELTHGIRGADISGIEFDGVPVDDTDVLSEPG
CCCCEEEEEEEHHHHHCCCCCCHHHHCHHHHHCCCCCCCCCCEEECCCCCCCHHHHCCCC
RGLENVMKALQLTRTLCCSLSVGAAERGLHTAVSFAESRELYGRKLIELPQARRVLTDAL
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
ADHLLNEVTTCAAIRSIHTLPAELSLHAAAAKYWVPTRTEALLAALRSFVGARAVLDSDD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCCC
PTAPALSRIERDHRIVSLFDGNTVVNLTTLITQFPVIGRGDLPADSAALVAAAPDADLSR
CCHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHH
LSLMSRSGSTLLRTLGDAVIQLDGHDLPDGCRRTASALAAVARDIVRAAADAPRNPAETP
HHHHHCCCHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NASFALAERLAAAIAGAAAVHVYLAYAGTIDSPLWRDGLWLRLALPRALAGADPAAPPSG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHCCCCCCCCCCC
PDGDHDAAIAALESLNRSDAGFSVLANVLDDETGDRV
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]