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The map label for this gene is aroK [H]

Identifier: 169629926

GI number: 169629926

Start: 2891471

End: 2892121

Strand: Reverse

Name: aroK [H]

Synonym: MAB_2842c

Alternate gene names: 169629926

Gene position: 2892121-2891471 (Counterclockwise)

Preceding gene: 169629927

Following gene: 169629925

Centisome position: 57.08

GC content: 65.59

Gene sequence:

>651_bases
ATGAGCCCCAAAGCCGTTCTCGTCGGACTGCCCGGATCGGGTAAGTCCACCATTGGCCGTCGGCTGGCAAAAGCATTGGG
CGTCAATGTTTATGACACCGATACCGGTATCGAAACCGAGGCCGGGCGCACCATCGCGCAGATCTTCGCCAACGATGGGG
AGCCGGAGTTCCGGCGCATCGAGGAGTCAGTGATTCGGCAGGCGCTCGACCAGCAGGACGGGGTCGTGTCGTTGGGCGGT
GGCGCCGTACTGACCCCTGGCGTACGTGAGGCACTCGCCGGGCACACCGTGGTGTATTTGGAAATCAGTGCCGCAGAGGG
CATTCGGCGCACCGGTGGCAGCGTGGTACGCCCACTTCTGGCGGGACCGGACCGCGCCGAAAAGTACCACGCCCTGATGT
CGCAGCGGGTGCCGCTGTACCGGGAAGTCGCCACCATCAAGGTCAACACCGACAGGAGAAATCCGGGTGCGGTGGTGCGA
ATGATTGTGTCCCGGTTGGAGAACCCCGAGGGCAGCGCGGGCTCGGCCTCGTCACGGCGGCGTCGCCCGCGCCGGCGCCC
CCGTTCGCGGCGGCGTAGCGCAGGCGCTGCGGCGGTAACCCAAACCAATACCTCCGGAACCGAAACCAGGGAGAGAGCCG
ACAATGACTAG

Upstream 100 bases:

>100_bases
AGACCAATGTCGCTGCGTACCTTGATGCTGTGGCGCAGCGGGAGCCGCGCCAAGAATCTTCTGATGAGCAGCCTGCGCGA
AGAGCGGCTAACACAGCGGG

Downstream 100 bases:

>100_bases
CGCCAACCCGACGACGATCACCGTCGAGGTGAACCCGCCTTACCCGGTCATCGTGGGGACGGGTCTGCTGGGTGAGTTGG
TGGATAATCTGAAGGGCTCG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSPKAVLVGLPGSGKSTIGRRLAKALGVNVYDTDTGIETEAGRTIAQIFANDGEPEFRRIEESVIRQALDQQDGVVSLGG
GAVLTPGVREALAGHTVVYLEISAAEGIRRTGGSVVRPLLAGPDRAEKYHALMSQRVPLYREVATIKVNTDRRNPGAVVR
MIVSRLENPEGSAGSASSRRRRPRRRPRSRRRSAGAAAVTQTNTSGTETRERADND

Sequences:

>Translated_216_residues
MSPKAVLVGLPGSGKSTIGRRLAKALGVNVYDTDTGIETEAGRTIAQIFANDGEPEFRRIEESVIRQALDQQDGVVSLGG
GAVLTPGVREALAGHTVVYLEISAAEGIRRTGGSVVRPLLAGPDRAEKYHALMSQRVPLYREVATIKVNTDRRNPGAVVR
MIVSRLENPEGSAGSASSRRRRPRRRPRSRRRSAGAAAVTQTNTSGTETRERADND
>Mature_215_residues
SPKAVLVGLPGSGKSTIGRRLAKALGVNVYDTDTGIETEAGRTIAQIFANDGEPEFRRIEESVIRQALDQQDGVVSLGGG
AVLTPGVREALAGHTVVYLEISAAEGIRRTGGSVVRPLLAGPDRAEKYHALMSQRVPLYREVATIKVNTDRRNPGAVVRM
IVSRLENPEGSAGSASSRRRRPRRRPRSRRRSAGAAAVTQTNTSGTETRERADND

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=39.1566265060241, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1786587, Length=170, Percent_Identity=30, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 23194; Mature: 23063

Theoretical pI: Translated: 11.40; Mature: 11.40

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPKAVLVGLPGSGKSTIGRRLAKALGVNVYDTDTGIETEAGRTIAQIFANDGEPEFRRI
CCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCHHHHHH
EESVIRQALDQQDGVVSLGGGAVLTPGVREALAGHTVVYLEISAAEGIRRTGGSVVRPLL
HHHHHHHHHHHCCCEEEECCCEEECCHHHHHHCCCEEEEEEECCHHHHHHCCHHHHHHHH
AGPDRAEKYHALMSQRVPLYREVATIKVNTDRRNPGAVVRMIVSRLENPEGSAGSASSRR
CCCCHHHHHHHHHHHCCCHHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
RRPRRRPRSRRRSAGAAAVTQTNTSGTETRERADND
HCHHCCHHHHHHHCCCCEEEECCCCCCHHHHHCCCC
>Mature Secondary Structure 
SPKAVLVGLPGSGKSTIGRRLAKALGVNVYDTDTGIETEAGRTIAQIFANDGEPEFRRI
CCCEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCHHHHHH
EESVIRQALDQQDGVVSLGGGAVLTPGVREALAGHTVVYLEISAAEGIRRTGGSVVRPLL
HHHHHHHHHHHCCCEEEECCCEEECCHHHHHHCCCEEEEEEECCHHHHHHCCHHHHHHHH
AGPDRAEKYHALMSQRVPLYREVATIKVNTDRRNPGAVVRMIVSRLENPEGSAGSASSRR
CCCCHHHHHHHHHHHCCCHHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
RRPRRRPRSRRRSAGAAAVTQTNTSGTETRERADND
HCHHCCHHHHHHHCCCCEEEECCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]