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The map label for this gene is aroC

Identifier: 169629927

GI number: 169629927

Start: 2892118

End: 2893356

Strand: Reverse

Name: aroC

Synonym: MAB_2843c

Alternate gene names: 169629927

Gene position: 2893356-2892118 (Counterclockwise)

Preceding gene: 169629928

Following gene: 169629926

Centisome position: 57.1

GC content: 68.6

Gene sequence:

>1239_bases
GTGTTGCGCTGGATCACGGCAGGTGAATCGCACGGACGCGCGCTGGTCGCGGTCTTGGAAGGCATGGTCGCTGGTGTCGA
ACTGACATCGGAGGACATCGGCAGGCAGCTGGCACGCCGCCGCCTGGGCTACGGCCGCGGTGCCCGGATGGCCTTCGAGG
CCGACCAGGTCACCATGCTCGGAGGTGTGCGCCACGGTCTGACGTTGGGCGGCCCGGTGGCGATCGAGGTCGGCAACACC
GAGTGGCCCAAGTGGGAGACCGTGATGTCTCCGGACCCGGTTGACCCCGCCGAGCTGCAGAACATCGCACGCAATGCGCC
GTTGACCAGGCCCCGTCCCGGGCATGCCGACTACGCGGGCATGCTCAAGTACGGGTTTGACGACGCCCGCCCGGTGCTGG
AACGCGCCAGTGCGCGCGAGACCGCGGCCCGTGTGGCGGTGGGCACCCTTGCCAAGGCCTTCCTCAAGCAGGCTCTGGGC
GTCGATGTCATCTCGCACGTCATTTCCATTGGTGACTCCGACCCGTATGAGGGGCCGGTGCCCGATGCGGCGGATCTGGC
TGCCATCGACGCCAGCCCCGTGCGCGCTTTCGACGCGCAGGCCGAGTCTTCGATGATCAGCGAGATCGAGGCCGCCAAGA
AGGACGGCGACACCCTCGGCGGTGTGGTGGAGGTCGTGGTTGCCGGACTGCCCGTCGGCCTGGGCTCGTTCATCAGCGGG
CAGGACCGGCTGGACAGCCAGCTCGCCGCCGCCATCATGGGCATTCAGGCCATCAAGGGTGTCGAGATCGGCGATGGATT
CACCACGGCGCGCCGCCGGGGCAGCGCGGCGCACGACGAGATCTACCCCGGACCCGACGGCATCCTGCGTTCCACAAACC
GCGCCGGTGGCCTGGAAGGCGGTATGACCAACGGCCAGCCGCTGCGGGTGCGTGCGGCCATGAAGCCCATCTCCACCGTC
CCACGGGCGTTGGCGACCGTGGACATGTCCACGGGCGATGAGGCGGTCGCGATCCACCAGCGTTCGGACGTGTGCGCGGT
TCCGGCCGCCGGCGTGGTCGCCGAGGCCATGGTCGCGCTGGTGGTGGCCCGCGCCGCCCTGGAGAAGTTCGGCGGTGACT
CCCTGTCCGAGACCAAGACCAATGTCGCTGCGTACCTTGATGCTGTGGCGCAGCGGGAGCCGCGCCAAGAATCTTCTGAT
GAGCAGCCTGCGCGAAGAGCGGCTAACACAGCGGGATGA

Upstream 100 bases:

>100_bases
GGCCGGGCTGGGCGCCACGACACCGGGTATCTGACAAAGAAGCATCCACTGCGCCGATCGATTTGGAGGACCGACCTGCC
CGCATGGGACAATGGAAGAC

Downstream 100 bases:

>100_bases
GCCCCAAAGCCGTTCTCGTCGGACTGCCCGGATCGGGTAAGTCCACCATTGGCCGTCGGCTGGCAAAAGCATTGGGCGTC
AATGTTTATGACACCGATAC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MLRWITAGESHGRALVAVLEGMVAGVELTSEDIGRQLARRRLGYGRGARMAFEADQVTMLGGVRHGLTLGGPVAIEVGNT
EWPKWETVMSPDPVDPAELQNIARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAVGTLAKAFLKQALG
VDVISHVISIGDSDPYEGPVPDAADLAAIDASPVRAFDAQAESSMISEIEAAKKDGDTLGGVVEVVVAGLPVGLGSFISG
QDRLDSQLAAAIMGIQAIKGVEIGDGFTTARRRGSAAHDEIYPGPDGILRSTNRAGGLEGGMTNGQPLRVRAAMKPISTV
PRALATVDMSTGDEAVAIHQRSDVCAVPAAGVVAEAMVALVVARAALEKFGGDSLSETKTNVAAYLDAVAQREPRQESSD
EQPARRAANTAG

Sequences:

>Translated_412_residues
MLRWITAGESHGRALVAVLEGMVAGVELTSEDIGRQLARRRLGYGRGARMAFEADQVTMLGGVRHGLTLGGPVAIEVGNT
EWPKWETVMSPDPVDPAELQNIARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAVGTLAKAFLKQALG
VDVISHVISIGDSDPYEGPVPDAADLAAIDASPVRAFDAQAESSMISEIEAAKKDGDTLGGVVEVVVAGLPVGLGSFISG
QDRLDSQLAAAIMGIQAIKGVEIGDGFTTARRRGSAAHDEIYPGPDGILRSTNRAGGLEGGMTNGQPLRVRAAMKPISTV
PRALATVDMSTGDEAVAIHQRSDVCAVPAAGVVAEAMVALVVARAALEKFGGDSLSETKTNVAAYLDAVAQREPRQESSD
EQPARRAANTAG
>Mature_412_residues
MLRWITAGESHGRALVAVLEGMVAGVELTSEDIGRQLARRRLGYGRGARMAFEADQVTMLGGVRHGLTLGGPVAIEVGNT
EWPKWETVMSPDPVDPAELQNIARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAVGTLAKAFLKQALG
VDVISHVISIGDSDPYEGPVPDAADLAAIDASPVRAFDAQAESSMISEIEAAKKDGDTLGGVVEVVVAGLPVGLGSFISG
QDRLDSQLAAAIMGIQAIKGVEIGDGFTTARRRGSAAHDEIYPGPDGILRSTNRAGGLEGGMTNGQPLRVRAAMKPISTV
PRALATVDMSTGDEAVAIHQRSDVCAVPAAGVVAEAMVALVVARAALEKFGGDSLSETKTNVAAYLDAVAQREPRQESSD
EQPARRAANTAG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=371, Percent_Identity=36.1185983827493, Blast_Score=174, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=33.42175066313, Blast_Score=178, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_MYCA9 (B1MCF1)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703576.1
- ProteinModelPortal:   B1MCF1
- SMR:   B1MCF1
- EnsemblBacteria:   EBMYCT00000006567
- GeneID:   5965351
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2843c
- GeneTree:   EBGT00050000016560
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   MABS561007:MAB_2843C-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42956; Mature: 42956

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRWITAGESHGRALVAVLEGMVAGVELTSEDIGRQLARRRLGYGRGARMAFEADQVTML
CCEEEECCCCCCHHHHHHHHHHHHCCEECHHHHHHHHHHHHHCCCCCCCEEECCCCCHHH
GGVRHGLTLGGPVAIEVGNTEWPKWETVMSPDPVDPAELQNIARNAPLTRPRPGHADYAG
HHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHH
MLKYGFDDARPVLERASARETAARVAVGTLAKAFLKQALGVDVISHVISIGDSDPYEGPV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PDAADLAAIDASPVRAFDAQAESSMISEIEAAKKDGDTLGGVVEVVVAGLPVGLGSFISG
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCC
QDRLDSQLAAAIMGIQAIKGVEIGDGFTTARRRGSAAHDEIYPGPDGILRSTNRAGGLEG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCC
GMTNGQPLRVRAAMKPISTVPRALATVDMSTGDEAVAIHQRSDVCAVPAAGVVAEAMVAL
CCCCCCCEEEHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCEECCCCHHHHHHHHHHH
VVARAALEKFGGDSLSETKTNVAAYLDAVAQREPRQESSDEQPARRAANTAG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MLRWITAGESHGRALVAVLEGMVAGVELTSEDIGRQLARRRLGYGRGARMAFEADQVTML
CCEEEECCCCCCHHHHHHHHHHHHCCEECHHHHHHHHHHHHHCCCCCCCEEECCCCCHHH
GGVRHGLTLGGPVAIEVGNTEWPKWETVMSPDPVDPAELQNIARNAPLTRPRPGHADYAG
HHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHH
MLKYGFDDARPVLERASARETAARVAVGTLAKAFLKQALGVDVISHVISIGDSDPYEGPV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PDAADLAAIDASPVRAFDAQAESSMISEIEAAKKDGDTLGGVVEVVVAGLPVGLGSFISG
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCC
QDRLDSQLAAAIMGIQAIKGVEIGDGFTTARRRGSAAHDEIYPGPDGILRSTNRAGGLEG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCC
GMTNGQPLRVRAAMKPISTVPRALATVDMSTGDEAVAIHQRSDVCAVPAAGVVAEAMVAL
CCCCCCCEEEHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCEECCCCHHHHHHHHHHH
VVARAALEKFGGDSLSETKTNVAAYLDAVAQREPRQESSDEQPARRAANTAG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA