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The map label for this gene is gapA [H]

Identifier: 169629863

GI number: 169629863

Start: 2826128

End: 2827150

Strand: Reverse

Name: gapA [H]

Synonym: MAB_2779c

Alternate gene names: 169629863

Gene position: 2827150-2826128 (Counterclockwise)

Preceding gene: 169629864

Following gene: 169629862

Centisome position: 55.79

GC content: 64.81

Gene sequence:

>1023_bases
GTGACTGTCCGGGTAGGCGTAAACGGGTTTGGCCGGATCGGCCGGAACTTCTTTCGGGCACTGGACGCGCAGAAGGCTCA
AGGGGTCAACACTGACATCGAGATCGTCGCGGTCAACGACCTGACCGATAACGCCACCCTGGCCCACCTGCTGAAGTTCG
ACTCCATCCTGGGCCGGCTGCCCTATGACGTCAGCCTGGAGGGCGATGACACGATCGTCGTCGGCGATCACAAGATCAAG
GCGCTCGAGGTCAAGGAGGGTCCTGCGGCCCTTCCCTGGGGCGACCTGGGCGTTGACGTCGTCGTCGAGTCGACCGGCAT
CTTCACCGCACGCGCCAAGGCGCAGGGTCACCTGGACGCCGGCGCCAAGAAGGTCATCATCTCCGCGCCGGCCAGCGACG
AGGACATCACCATCGTGCTGGGCGTCAACGACGACAAGTACGACGGCAGCCAGAACATCATCTCGAACGCCTCGTGCACC
ACGAACTGCCTGGGCCCGCTCGCCAAGGTCCTCAACGACGAGTTCGGCATCGTCAAGGGCCTGATGACCACCATCCACGC
CTACACGCAGGACCAGAACCTGCAGGACGGCCCGCATAAGGATCTGCGCCGTGCTCGCGCCGCCGCCCTGAACATCGTGC
CGACCTCCACCGGTGCCGCCAAGGCCATCGGCCTGGTGCTCCCCGAGCTCAAGGGCAAGCTCGACGGCTACGCCCTGCGC
GTGCCGATCCCCACCGGTTCGGCGACCGACCTCACCGTCGAACTCAAGAAGGCCGCCAGCGCCGATGAGATCAATGCCGC
GATGAAGGCCGCCGCCGAGGGCAAGCTCAAGGGCATTCTCAAGTACTACGACGCGCCGATCGTCTCCTCGGACATCGTCA
CCGACCCGCACAGCTCGATCTTCGACGCGGGTCTGACCAAGGTGATCGACGACCAGGCCAAGGTGGTCTCCTGGTACGAC
AACGAGTGGGGCTACTCGAACCGCCTCGTCGACCTGGTCGGCCTGGTCGGCAAGTCGCTGTAA

Upstream 100 bases:

>100_bases
TCGCGCGACTGGGCCGGGACGAAATGGCTCACCCCCTGGGCTAATGTGAGTGCCGATAACGGGTACACCACATCTCAAAC
CGACAAAGAGGGAGCGCTAC

Downstream 100 bases:

>100_bases
CGATGGCGATCAAGTCCCTCAACGACCTGTTGGCCGAGGGAGTTTCGGGCAAGGGCGTGCTGGTCCGGTCGGACCTGAAC
GTCCCGCTCGAGTACCTGGA

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTVRVGVNGFGRIGRNFFRALDAQKAQGVNTDIEIVAVNDLTDNATLAHLLKFDSILGRLPYDVSLEGDDTIVVGDHKIK
ALEVKEGPAALPWGDLGVDVVVESTGIFTARAKAQGHLDAGAKKVIISAPASDEDITIVLGVNDDKYDGSQNIISNASCT
TNCLGPLAKVLNDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVLPELKGKLDGYALR
VPIPTGSATDLTVELKKAASADEINAAMKAAAEGKLKGILKYYDAPIVSSDIVTDPHSSIFDAGLTKVIDDQAKVVSWYD
NEWGYSNRLVDLVGLVGKSL

Sequences:

>Translated_340_residues
MTVRVGVNGFGRIGRNFFRALDAQKAQGVNTDIEIVAVNDLTDNATLAHLLKFDSILGRLPYDVSLEGDDTIVVGDHKIK
ALEVKEGPAALPWGDLGVDVVVESTGIFTARAKAQGHLDAGAKKVIISAPASDEDITIVLGVNDDKYDGSQNIISNASCT
TNCLGPLAKVLNDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVLPELKGKLDGYALR
VPIPTGSATDLTVELKKAASADEINAAMKAAAEGKLKGILKYYDAPIVSSDIVTDPHSSIFDAGLTKVIDDQAKVVSWYD
NEWGYSNRLVDLVGLVGKSL
>Mature_339_residues
TVRVGVNGFGRIGRNFFRALDAQKAQGVNTDIEIVAVNDLTDNATLAHLLKFDSILGRLPYDVSLEGDDTIVVGDHKIKA
LEVKEGPAALPWGDLGVDVVVESTGIFTARAKAQGHLDAGAKKVIISAPASDEDITIVLGVNDDKYDGSQNIISNASCTT
NCLGPLAKVLNDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVLPELKGKLDGYALRV
PIPTGSATDLTVELKKAASADEINAAMKAAAEGKLKGILKYYDAPIVSSDIVTDPHSSIFDAGLTKVIDDQAKVVSWYDN
EWGYSNRLVDLVGLVGKSL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=335, Percent_Identity=51.044776119403, Blast_Score=311, Evalue=6e-85,
Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=48.6486486486487, Blast_Score=301, Evalue=4e-82,
Organism=Escherichia coli, GI1788079, Length=340, Percent_Identity=52.9411764705882, Blast_Score=336, Evalue=1e-93,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=45.045045045045, Blast_Score=293, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI17534677, Length=341, Percent_Identity=53.9589442815249, Blast_Score=334, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17534679, Length=341, Percent_Identity=53.9589442815249, Blast_Score=333, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI32566163, Length=340, Percent_Identity=52.9411764705882, Blast_Score=318, Evalue=3e-87,
Organism=Caenorhabditis elegans, GI17568413, Length=340, Percent_Identity=52.9411764705882, Blast_Score=318, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6322468, Length=340, Percent_Identity=52.0588235294118, Blast_Score=325, Evalue=7e-90,
Organism=Saccharomyces cerevisiae, GI6321631, Length=340, Percent_Identity=52.0588235294118, Blast_Score=322, Evalue=7e-89,
Organism=Saccharomyces cerevisiae, GI6322409, Length=340, Percent_Identity=51.7647058823529, Blast_Score=321, Evalue=1e-88,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=51.3513513513513, Blast_Score=310, Evalue=9e-85,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=51.3513513513513, Blast_Score=310, Evalue=9e-85,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=50.7507507507508, Blast_Score=307, Evalue=5e-84,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=50.7507507507508, Blast_Score=307, Evalue=5e-84,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=48.4939759036145, Blast_Score=295, Evalue=3e-80,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36030; Mature: 35899

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRVGVNGFGRIGRNFFRALDAQKAQGVNTDIEIVAVNDLTDNATLAHLLKFDSILGRL
CEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
PYDVSLEGDDTIVVGDHKIKALEVKEGPAALPWGDLGVDVVVESTGIFTARAKAQGHLDA
CCEEEECCCCEEEECCCEEEEEEECCCCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCC
GAKKVIISAPASDEDITIVLGVNDDKYDGSQNIISNASCTTNCLGPLAKVLNDEFGIVKG
CCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCHHHHHHH
LMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVLPELKGKLDGYALR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEE
VPIPTGSATDLTVELKKAASADEINAAMKAAAEGKLKGILKYYDAPIVSSDIVTDPHSSI
EECCCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
FDAGLTKVIDDQAKVVSWYDNEWGYSNRLVDLVGLVGKSL
HHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVRVGVNGFGRIGRNFFRALDAQKAQGVNTDIEIVAVNDLTDNATLAHLLKFDSILGRL
EEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
PYDVSLEGDDTIVVGDHKIKALEVKEGPAALPWGDLGVDVVVESTGIFTARAKAQGHLDA
CCEEEECCCCEEEECCCEEEEEEECCCCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCC
GAKKVIISAPASDEDITIVLGVNDDKYDGSQNIISNASCTTNCLGPLAKVLNDEFGIVKG
CCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCHHHHHHH
LMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVLPELKGKLDGYALR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEE
VPIPTGSATDLTVELKKAASADEINAAMKAAAEGKLKGILKYYDAPIVSSDIVTDPHSSI
EECCCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
FDAGLTKVIDDQAKVVSWYDNEWGYSNRLVDLVGLVGKSL
HHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA