Click here to switch to the map view.

The map label for this gene is bioD

Identifier: 169629771

GI number: 169629771

Start: 2727898

End: 2728575

Strand: Reverse

Name: bioD

Synonym: MAB_2686c

Alternate gene names: 169629771

Gene position: 2728575-2727898 (Counterclockwise)

Preceding gene: 169629772

Following gene: 169629769

Centisome position: 53.85

GC content: 66.96

Gene sequence:

>678_bases
ATGACGATTTTGCTGGTCACCGGCACATCGACCGGGGTGGGCAAGACGGTGGCGACGGCTGCGCTGGCCGCCGCGGCTGT
CCGTCAGGGCATCGACGTGACGGTGTGTAAACCCGTGCAGACCGGCGATGACCATGACGCTGGCGAGGTGGCGCGGCTCT
CCGGCGTGACGCGGGTCCAGACCCTGGTGCGCTATCCCGAGCCGCTGGCCCCGGTGGCCTCGGCGTCACGGGCTGGATTG
GAACTGCTGGACCACACGCAGATGGCCACTGCGATCGTTGCCCTCGATCGGCCCGGCGCCTTGACCTTGGTCGAGGGCGC
TGGCGGTCTGCTGGTGGAGTTGGCGGCCGACGGCAAGACTCTTCGCGACCTCGCGATGGTCCTCGATGCCCCAGTGCTGG
TGGTGACCACCGCCGATCTAGGCACCCTGAATCACACCGCCCTTACCCTGGAAGCTCTTGCCGTACAGTCGGTTCCCTGT
GCAGGACTGGTGGTGGGTAGCTTTCCGGCAGAGCCCGATCTGGCGCAACGGCTCAACCGTGAAAACCTGGCGAACCAGTT
CGGGACGCCCGTGCGCGCGGTGATTCCCGAGGGTGCGGCGCGGCTCATGCCCCCGGTATTCGCGGAGCTGAGTATCGAAC
TTTTCGAACCGCAGTGGGTCGCCGGCCTGGTCGCCTAA

Upstream 100 bases:

>100_bases
GTCAGTCGCTGTTGCGACTGACGGCCCGCGCCTCGCTCACCGAGGCCGATATGGAACGCGTGCACGAGGTGCTTGCCGGG
GTGCTGACGCTGGCGCGGCG

Downstream 100 bases:

>100_bases
CCGATCGGACTGGACTGACGGGCCAACTGGCCGATCCCGTCCACCAGAAGGCGCGCGCCGAAACCGAATTGCGCGCTGGG
ATCGGCGAACCCCGCGCCGT

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTILLVTGTSTGVGKTVATAALAAAAVRQGIDVTVCKPVQTGDDHDAGEVARLSGVTRVQTLVRYPEPLAPVASASRAGL
ELLDHTQMATAIVALDRPGALTLVEGAGGLLVELAADGKTLRDLAMVLDAPVLVVTTADLGTLNHTALTLEALAVQSVPC
AGLVVGSFPAEPDLAQRLNRENLANQFGTPVRAVIPEGAARLMPPVFAELSIELFEPQWVAGLVA

Sequences:

>Translated_225_residues
MTILLVTGTSTGVGKTVATAALAAAAVRQGIDVTVCKPVQTGDDHDAGEVARLSGVTRVQTLVRYPEPLAPVASASRAGL
ELLDHTQMATAIVALDRPGALTLVEGAGGLLVELAADGKTLRDLAMVLDAPVLVVTTADLGTLNHTALTLEALAVQSVPC
AGLVVGSFPAEPDLAQRLNRENLANQFGTPVRAVIPEGAARLMPPVFAELSIELFEPQWVAGLVA
>Mature_224_residues
TILLVTGTSTGVGKTVATAALAAAAVRQGIDVTVCKPVQTGDDHDAGEVARLSGVTRVQTLVRYPEPLAPVASASRAGLE
LLDHTQMATAIVALDRPGALTLVEGAGGLLVELAADGKTLRDLAMVLDAPVLVVTTADLGTLNHTALTLEALAVQSVPCA
GLVVGSFPAEPDLAQRLNRENLANQFGTPVRAVIPEGAARLMPPVFAELSIELFEPQWVAGLVA

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family

Homologues:

Organism=Escherichia coli, GI1786995, Length=172, Percent_Identity=31.9767441860465, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BIOD_MYCA9 (B1MBZ5)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703420.1
- ProteinModelPortal:   B1MBZ5
- EnsemblBacteria:   EBMYCT00000008235
- GeneID:   5965195
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2686c
- GeneTree:   EBGT00050000017652
- HOGENOM:   HBG650065
- OMA:   IDTIVAC
- ProtClustDB:   PRK00090
- BioCyc:   MABS561007:MAB_2686C-MONOMER
- HAMAP:   MF_00336
- InterPro:   IPR004472
- InterPro:   IPR002586
- PIRSF:   PIRSF006755
- TIGRFAMs:   TIGR00347

Pfam domain/function: PF01656 CbiA

EC number: =6.3.3.3

Molecular weight: Translated: 23095; Mature: 22964

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILLVTGTSTGVGKTVATAALAAAAVRQGIDVTVCKPVQTGDDHDAGEVARLSGVTRVQ
CEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
TLVRYPEPLAPVASASRAGLELLDHTQMATAIVALDRPGALTLVEGAGGLLVELAADGKT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCEEEEEECCCHH
LRDLAMVLDAPVLVVTTADLGTLNHTALTLEALAVQSVPCAGLVVGSFPAEPDLAQRLNR
HHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHCCH
ENLANQFGTPVRAVIPEGAARLMPPVFAELSIELFEPQWVAGLVA
HHHHHHHCCCEEEECCCCHHHHCCHHHHHHEEEEECCHHHHHCCC
>Mature Secondary Structure 
TILLVTGTSTGVGKTVATAALAAAAVRQGIDVTVCKPVQTGDDHDAGEVARLSGVTRVQ
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
TLVRYPEPLAPVASASRAGLELLDHTQMATAIVALDRPGALTLVEGAGGLLVELAADGKT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCEEEEEECCCHH
LRDLAMVLDAPVLVVTTADLGTLNHTALTLEALAVQSVPCAGLVVGSFPAEPDLAQRLNR
HHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHCCH
ENLANQFGTPVRAVIPEGAARLMPPVFAELSIELFEPQWVAGLVA
HHHHHHHCCCEEEECCCCHHHHCCHHHHHHEEEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA