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The map label for this gene is hisC [H]

Identifier: 169629754

GI number: 169629754

Start: 2710255

End: 2711385

Strand: Reverse

Name: hisC [H]

Synonym: MAB_2669c

Alternate gene names: 169629754

Gene position: 2711385-2710255 (Counterclockwise)

Preceding gene: 169629755

Following gene: 169629753

Centisome position: 53.51

GC content: 64.46

Gene sequence:

>1131_bases
ATGAGCGTGCCGATCGGTGGCTCGGCCCGGCTGGAGGACCTGCCGCTGCGGGACAGCCTGCGCGGCAAGAGTCCCTACGG
CGCGCCGCAATTGACAGTGCCGGTACGGCTGAACACCAACGAGAACCCGCACGAGCCGTCGGCAGGCCTGGTGGACGACG
TCGCAGCCTCCATCCGTGAGGTAGCGGGGGAGCTACACCGCTATCCGGATCGTGACGCGGTTGCCCTACGTACGGATTTG
GCCACCTACCTCACGGAGCAGACGGGCGTGCCTGTCGTGGCCGAGAATGTCTGGGCGGCAAATGGTTCCAATGAGGTGCT
GCAACAGCTCTTGCAGGCCTTCGGCGGTCCGGGCCGCAGGGCGCTGGGGTTCACGCCGTCCTATTCGATGCATCCGATCA
TCTCGGACGGAACCCAAACCGAGTGGCTGCAGGCGCAGCGTTCGGAGGACTTCTCGCTGGATGTCGGCAGTGCGGTGGCT
GCCGTGCGGGAACGTAAGCCCGACGTGGTCTTCGTGACGAGCCCCAACAACCCGACGGGGCAGTCGATTCCGTTGGATGC
GCTCCGCCGGATTCTCGACGTGGCACCGGGCGTGGTAATTCTGGACGAGGCGTACGGCGAGTTCTCGGCGGCGCCGAGTG
GGATCACGCTCGTTGATGAGTATCCCGCGAAACTGATCGTCAGTCGGACCATGAGCAAGGCGTTTGCCTTCGCGGGCGGG
CGGCTCGGATACCTGGTGGCGGCCCCGGCTGTCATCGATGCCCTGTTATTGGTGCGCTTGCCGTACCACCTTTCGGTGCT
GACCCAAGCAGCCGCGCGTGCCGCTGTGAAACACCGCGCCGAGACTCTCGGCAGCGTCGCGACGTTGGTCGCGGAGCGCA
TTCGGGTATCGGAAGCCTTGTCGGCCAGCGGGTTCCGGGTGATTCCCAGTGACGCCAATTTTATCCTGTTCGGCAGATTC
GCGGATGCCGCGGCGAGCTGGCGGCGGTACCTGGATGCGGGTGTTCTCATTCGGGATGTCGGCATTCCGGGTTATCTGCG
TGTGACTGTCGGACTGGCGAGCGAGAATGACGTGTTCTTGAAGGTCAGCGACAGTCTGGCTGCGACGGACCTAGAAGTGG
AGGCATCATGA

Upstream 100 bases:

>100_bases
AAGCGGCACTCAAAGAGGTCGCCGGGCATGTGATCACACTGGCTAACGCCGAGAATCTGCCCGCGCACGGTGAGGCCGTC
CGACGCAGGTTCGAGCGATC

Downstream 100 bases:

>100_bases
CGGTTCCAACTCAGGCGCGGACAGCGCGCGTGGCGCGGGCCACCCGTGAGTCGGACATCGTGGTGGAACTGAACCTGGAC
GGGTCCGGCCAGGTACAGAT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSVPIGGSARLEDLPLRDSLRGKSPYGAPQLTVPVRLNTNENPHEPSAGLVDDVAASIREVAGELHRYPDRDAVALRTDL
ATYLTEQTGVPVVAENVWAANGSNEVLQQLLQAFGGPGRRALGFTPSYSMHPIISDGTQTEWLQAQRSEDFSLDVGSAVA
AVRERKPDVVFVTSPNNPTGQSIPLDALRRILDVAPGVVILDEAYGEFSAAPSGITLVDEYPAKLIVSRTMSKAFAFAGG
RLGYLVAAPAVIDALLLVRLPYHLSVLTQAAARAAVKHRAETLGSVATLVAERIRVSEALSASGFRVIPSDANFILFGRF
ADAAASWRRYLDAGVLIRDVGIPGYLRVTVGLASENDVFLKVSDSLAATDLEVEAS

Sequences:

>Translated_376_residues
MSVPIGGSARLEDLPLRDSLRGKSPYGAPQLTVPVRLNTNENPHEPSAGLVDDVAASIREVAGELHRYPDRDAVALRTDL
ATYLTEQTGVPVVAENVWAANGSNEVLQQLLQAFGGPGRRALGFTPSYSMHPIISDGTQTEWLQAQRSEDFSLDVGSAVA
AVRERKPDVVFVTSPNNPTGQSIPLDALRRILDVAPGVVILDEAYGEFSAAPSGITLVDEYPAKLIVSRTMSKAFAFAGG
RLGYLVAAPAVIDALLLVRLPYHLSVLTQAAARAAVKHRAETLGSVATLVAERIRVSEALSASGFRVIPSDANFILFGRF
ADAAASWRRYLDAGVLIRDVGIPGYLRVTVGLASENDVFLKVSDSLAATDLEVEAS
>Mature_375_residues
SVPIGGSARLEDLPLRDSLRGKSPYGAPQLTVPVRLNTNENPHEPSAGLVDDVAASIREVAGELHRYPDRDAVALRTDLA
TYLTEQTGVPVVAENVWAANGSNEVLQQLLQAFGGPGRRALGFTPSYSMHPIISDGTQTEWLQAQRSEDFSLDVGSAVAA
VRERKPDVVFVTSPNNPTGQSIPLDALRRILDVAPGVVILDEAYGEFSAAPSGITLVDEYPAKLIVSRTMSKAFAFAGGR
LGYLVAAPAVIDALLLVRLPYHLSVLTQAAARAAVKHRAETLGSVATLVAERIRVSEALSASGFRVIPSDANFILFGRFA
DAAASWRRYLDAGVLIRDVGIPGYLRVTVGLASENDVFLKVSDSLAATDLEVEAS

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=372, Percent_Identity=31.7204301075269, Blast_Score=131, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6322075, Length=376, Percent_Identity=27.1276595744681, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40053; Mature: 39922

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPIGGSARLEDLPLRDSLRGKSPYGAPQLTVPVRLNTNENPHEPSAGLVDDVAASIRE
CCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHH
VAGELHRYPDRDAVALRTDLATYLTEQTGVPVVAENVWAANGSNEVLQQLLQAFGGPGRR
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEECCEECCCCCHHHHHHHHHHHCCCCCC
ALGFTPSYSMHPIISDGTQTEWLQAQRSEDFSLDVGSAVAAVRERKPDVVFVTSPNNPTG
EECCCCCCCCCCEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
QSIPLDALRRILDVAPGVVILDEAYGEFSAAPSGITLVDEYPAKLIVSRTMSKAFAFAGG
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
RLGYLVAAPAVIDALLLVRLPYHLSVLTQAAARAAVKHRAETLGSVATLVAERIRVSEAL
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SASGFRVIPSDANFILFGRFADAAASWRRYLDAGVLIRDVGIPGYLRVTVGLASENDVFL
CCCCCEEECCCCCEEEEECHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEECCCCCEEE
KVSDSLAATDLEVEAS
EECCCCEEECEEEECC
>Mature Secondary Structure 
SVPIGGSARLEDLPLRDSLRGKSPYGAPQLTVPVRLNTNENPHEPSAGLVDDVAASIRE
CCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHH
VAGELHRYPDRDAVALRTDLATYLTEQTGVPVVAENVWAANGSNEVLQQLLQAFGGPGRR
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEECCEECCCCCHHHHHHHHHHHCCCCCC
ALGFTPSYSMHPIISDGTQTEWLQAQRSEDFSLDVGSAVAAVRERKPDVVFVTSPNNPTG
EECCCCCCCCCCEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
QSIPLDALRRILDVAPGVVILDEAYGEFSAAPSGITLVDEYPAKLIVSRTMSKAFAFAGG
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
RLGYLVAAPAVIDALLLVRLPYHLSVLTQAAARAAVKHRAETLGSVATLVAERIRVSEAL
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SASGFRVIPSDANFILFGRFADAAASWRRYLDAGVLIRDVGIPGYLRVTVGLASENDVFL
CCCCCEEECCCCCEEEEECHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEECCCCCEEE
KVSDSLAATDLEVEAS
EECCCCEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA