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The map label for this gene is ntdB [H]

Identifier: 169629697

GI number: 169629697

Start: 2650134

End: 2650964

Strand: Direct

Name: ntdB [H]

Synonym: MAB_2611

Alternate gene names: 169629697

Gene position: 2650134-2650964 (Clockwise)

Preceding gene: 169629696

Following gene: 169629698

Centisome position: 52.3

GC content: 62.94

Gene sequence:

>831_bases
ATGACGTCCTTGGTTGATATTCGCACGGCGACAGACTGGCTGGTGCTGTGCGATTTCGATGAGACATTCTTTGCTCATGA
CCCTGCGGTCCGCTCGCGACGCGACCTCGCTGACTTGGCAGCGCTGGTCAACAGCCTATCCGCCTCCCGGGGGCTCCGAT
TCGGGTTCATCACCGGGAGCGCCCCGTCGACAGTGATCGCGGTACTCGGCGATCTGGCCACGTCGCTACAGCCGGCGTTC
ATCGGTGGCAACTTGGGGACGGACCTACTGGTGGCAGATGCCTCCGGCGCACTCGTTCCCGATCTACTCTGGCATGCGAG
ATTCCCGGCGCCCGAGGAGTTTTCGGCCCGGGTAGACAGTGTACTGACGTCGCTGCCCGAGTTGATCCTCGCGCCGCAAT
CGACTCATGGGGCGGGCACCTACAAACGCAATTTCTATCTGCGCGCGGTGACGGAAAACCTCGATGACGACAGCCGGGTC
TGGTCGTTGCGGCAGGCGACGGCTGCGCACTCCCTCGCGATCAACGTCAACCACTGCAATCCCGCGGCCGGTGACCCCGA
GGGATACCTCGATGTCGACTTCCTGCCATTGGGTGCGGGCAAGCACGAAATCGCACGCTTCTTGCAGGAGACCTGGCAAG
TACCGGCAAGCCGCACATTGGCTTTCGGTGATAGTGGTAACGATCTCGGCATGCTCGCCTGTGCCGGGCACGCCTGGCTC
GTATCCAACGCCACTGCCGAGGCGCGCCAGGCCCATCCACACGTCACCGCCCGGCCGCACGCAGGCGGAATCGTCGACAC
CATCGCCAATATTCTTACGAAGGAGCAGTAG

Upstream 100 bases:

>100_bases
CGGCTACCCCGCACCGAGGCTGCACATGCACGAATGTTCCAGCTCCCGCTCTATCCCACGCTCACGCTTGCCGAACAAGA
CCGAGTGATTGGTGTCCTAC

Downstream 100 bases:

>100_bases
CCATGTTGAAAGTCGGAATTATCGGGGCCGGCGGTGTCGCCCGTGCCCACGCTCGCGCGCTGAACACCCTCAAATCTGCC
GAACTGGTGGGTGTATTGGA

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTSLVDIRTATDWLVLCDFDETFFAHDPAVRSRRDLADLAALVNSLSASRGLRFGFITGSAPSTVIAVLGDLATSLQPAF
IGGNLGTDLLVADASGALVPDLLWHARFPAPEEFSARVDSVLTSLPELILAPQSTHGAGTYKRNFYLRAVTENLDDDSRV
WSLRQATAAHSLAINVNHCNPAAGDPEGYLDVDFLPLGAGKHEIARFLQETWQVPASRTLAFGDSGNDLGMLACAGHAWL
VSNATAEARQAHPHVTARPHAGGIVDTIANILTKEQ

Sequences:

>Translated_276_residues
MTSLVDIRTATDWLVLCDFDETFFAHDPAVRSRRDLADLAALVNSLSASRGLRFGFITGSAPSTVIAVLGDLATSLQPAF
IGGNLGTDLLVADASGALVPDLLWHARFPAPEEFSARVDSVLTSLPELILAPQSTHGAGTYKRNFYLRAVTENLDDDSRV
WSLRQATAAHSLAINVNHCNPAAGDPEGYLDVDFLPLGAGKHEIARFLQETWQVPASRTLAFGDSGNDLGMLACAGHAWL
VSNATAEARQAHPHVTARPHAGGIVDTIANILTKEQ
>Mature_275_residues
TSLVDIRTATDWLVLCDFDETFFAHDPAVRSRRDLADLAALVNSLSASRGLRFGFITGSAPSTVIAVLGDLATSLQPAFI
GGNLGTDLLVADASGALVPDLLWHARFPAPEEFSARVDSVLTSLPELILAPQSTHGAGTYKRNFYLRAVTENLDDDSRVW
SLRQATAAHSLAINVNHCNPAAGDPEGYLDVDFLPLGAGKHEIARFLQETWQVPASRTLAFGDSGNDLGMLACAGHAWLV
SNATAEARQAHPHVTARPHAGGIVDTIANILTKEQ

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006380 [H]

Pfam domain/function: PF05116 S6PP [H]

EC number: NA

Molecular weight: Translated: 29460; Mature: 29329

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLVDIRTATDWLVLCDFDETFFAHDPAVRSRRDLADLAALVNSLSASRGLRFGFITGS
CCCEEEEEECCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
APSTVIAVLGDLATSLQPAFIGGNLGTDLLVADASGALVPDLLWHARFPAPEEFSARVDS
CHHHHHHHHHHHHHHCCCEEECCCCCCCEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHH
VLTSLPELILAPQSTHGAGTYKRNFYLRAVTENLDDDSRVWSLRQATAAHSLAINVNHCN
HHHHHHHHHCCCCCCCCCCCEEHEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCC
PAAGDPEGYLDVDFLPLGAGKHEIARFLQETWQVPASRTLAFGDSGNDLGMLACAGHAWL
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCEEE
VSNATAEARQAHPHVTARPHAGGIVDTIANILTKEQ
EECCCHHHHHCCCCCEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSLVDIRTATDWLVLCDFDETFFAHDPAVRSRRDLADLAALVNSLSASRGLRFGFITGS
CCEEEEEECCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
APSTVIAVLGDLATSLQPAFIGGNLGTDLLVADASGALVPDLLWHARFPAPEEFSARVDS
CHHHHHHHHHHHHHHCCCEEECCCCCCCEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHH
VLTSLPELILAPQSTHGAGTYKRNFYLRAVTENLDDDSRVWSLRQATAAHSLAINVNHCN
HHHHHHHHHCCCCCCCCCCCEEHEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCC
PAAGDPEGYLDVDFLPLGAGKHEIARFLQETWQVPASRTLAFGDSGNDLGMLACAGHAWL
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCEEE
VSNATAEARQAHPHVTARPHAGGIVDTIANILTKEQ
EECCCHHHHHCCCCCEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]