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The map label for this gene is ntdA [H]

Identifier: 169629696

GI number: 169629696

Start: 2648825

End: 2650150

Strand: Direct

Name: ntdA [H]

Synonym: MAB_2610

Alternate gene names: 169629696

Gene position: 2648825-2650150 (Clockwise)

Preceding gene: 169629695

Following gene: 169629697

Centisome position: 52.27

GC content: 63.2

Gene sequence:

>1326_bases
ATGTCTATTGCCGAATCCGCCAATGCGTCGGTGCGCACGGGACCGGCGCCGTCCTCGAAAACCCGGGAGTTCGCGCGGGC
GATACTCTCCGGTACCGCGGTGCATCCCGAGGAGATCCCTGCTGGTCGCGCATATACGACGCTACGAGACCTGGCCACCC
ATCCGGGTCTGCGCGATGTGACCGACGTGTTGATCCCGGGAAGCGCGCCCGACACGGTTGATTTCCTTCCGCTGGCGAGG
CTGGTCAACGCCGCCGAACTGCCTGCGATACGTGCTGCCATCGACAGCGTGTTGCCATCCGGCAAGTTCACCTCCGGCCC
CCATGTCGACGCATTCGAAGACGAAATTGCGACCTACCTGGGCATCGATCACGTAATCGGGGCCTCCAGCGGCACCGATG
CGATGACCGCGGTTCTGTTGGCGCTGGGTGCGGGGCCGGGAACCGAAGTCATCTTGCCCGCCAACAGTTTTGCCGCTACC
GAGAACGCGGTCTTCCTGACCGGTGCTCGGCCCGTCCTGGTGGATACCCGGGCAGACGACCACCTACTGGACCCCACCGA
AGTGGAGGCGGCCATCACGAGTCGCACGGTCGCGGTACTTCCCGTGCACCTCTACGGTGCGTTCGCCGATATCCATGCTC
TGACGGAGGTTACTTCGCGTCACGGAATCCCGGTAGTGGAGGACGGATGCCAGGGAATCGGCTTAGATGGGCTGGGCCAC
CACAGCGACGCGGCGATTCTCAGCTTCAATCCCTATAAGAATCTCGGCGCGGTGGGGAAAGCGGGCGCGGTGGCAACCCG
CTTACCCGGCCTTGCACGCCGAGTCACCGAACTGCTCTATCACGGCTTCGCCGCCGGCCAAAAGAATGTCAAGGCAGCCG
GATACGGTCTGAATTCACGCTTGGACAATCTGCAGGCAGCGGTTCTGCGCGCCCGACTCGATTGGCTCGGCGAGAACAAC
CTCGCCCGCAGCATTCTTGCCCGGCGATACGTCGACGGTCTGGCCGACCTGGCGGAGAGCGGGCTTCTTCGCCTGCCCCA
TTGGGATACCGACCACGTCTGGCATCTGTTCACCGTCGAAGTGACGAAGCATGACCGAGACAAGGTCACCGAGTCGCTGC
GAGCCGCAGGCGTCGCAACTGATCTCTACTACCCGGTGCTCACCCACCGGCACCGAGTGCCCTTGGTGGCAGACCTATTC
GAGGGAGTGCGGCTACCCCGCACCGAGGCTGCACATGCACGAATGTTCCAGCTCCCGCTCTATCCCACGCTCACGCTTGC
CGAACAAGACCGAGTGATTGGTGTCCTACATGACGTCCTTGGTTGA

Upstream 100 bases:

>100_bases
GACACGTTGCTTTTTGTGCCCGCCGTCGCATGACGCCCGGCGGAGCGGCGACAAGTCGCCATCACAGTTGATTAACCTGC
CTTCTTTCCGGGAGTGTCAT

Downstream 100 bases:

>100_bases
TATTCGCACGGCGACAGACTGGCTGGTGCTGTGCGATTTCGATGAGACATTCTTTGCTCATGACCCTGCGGTCCGCTCGC
GACGCGACCTCGCTGACTTG

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSIAESANASVRTGPAPSSKTREFARAILSGTAVHPEEIPAGRAYTTLRDLATHPGLRDVTDVLIPGSAPDTVDFLPLAR
LVNAAELPAIRAAIDSVLPSGKFTSGPHVDAFEDEIATYLGIDHVIGASSGTDAMTAVLLALGAGPGTEVILPANSFAAT
ENAVFLTGARPVLVDTRADDHLLDPTEVEAAITSRTVAVLPVHLYGAFADIHALTEVTSRHGIPVVEDGCQGIGLDGLGH
HSDAAILSFNPYKNLGAVGKAGAVATRLPGLARRVTELLYHGFAAGQKNVKAAGYGLNSRLDNLQAAVLRARLDWLGENN
LARSILARRYVDGLADLAESGLLRLPHWDTDHVWHLFTVEVTKHDRDKVTESLRAAGVATDLYYPVLTHRHRVPLVADLF
EGVRLPRTEAAHARMFQLPLYPTLTLAEQDRVIGVLHDVLG

Sequences:

>Translated_441_residues
MSIAESANASVRTGPAPSSKTREFARAILSGTAVHPEEIPAGRAYTTLRDLATHPGLRDVTDVLIPGSAPDTVDFLPLAR
LVNAAELPAIRAAIDSVLPSGKFTSGPHVDAFEDEIATYLGIDHVIGASSGTDAMTAVLLALGAGPGTEVILPANSFAAT
ENAVFLTGARPVLVDTRADDHLLDPTEVEAAITSRTVAVLPVHLYGAFADIHALTEVTSRHGIPVVEDGCQGIGLDGLGH
HSDAAILSFNPYKNLGAVGKAGAVATRLPGLARRVTELLYHGFAAGQKNVKAAGYGLNSRLDNLQAAVLRARLDWLGENN
LARSILARRYVDGLADLAESGLLRLPHWDTDHVWHLFTVEVTKHDRDKVTESLRAAGVATDLYYPVLTHRHRVPLVADLF
EGVRLPRTEAAHARMFQLPLYPTLTLAEQDRVIGVLHDVLG
>Mature_440_residues
SIAESANASVRTGPAPSSKTREFARAILSGTAVHPEEIPAGRAYTTLRDLATHPGLRDVTDVLIPGSAPDTVDFLPLARL
VNAAELPAIRAAIDSVLPSGKFTSGPHVDAFEDEIATYLGIDHVIGASSGTDAMTAVLLALGAGPGTEVILPANSFAATE
NAVFLTGARPVLVDTRADDHLLDPTEVEAAITSRTVAVLPVHLYGAFADIHALTEVTSRHGIPVVEDGCQGIGLDGLGHH
SDAAILSFNPYKNLGAVGKAGAVATRLPGLARRVTELLYHGFAAGQKNVKAAGYGLNSRLDNLQAAVLRARLDWLGENNL
ARSILARRYVDGLADLAESGLLRLPHWDTDHVWHLFTVEVTKHDRDKVTESLRAAGVATDLYYPVLTHRHRVPLVADLFE
GVRLPRTEAAHARMFQLPLYPTLTLAEQDRVIGVLHDVLG

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=387, Percent_Identity=35.4005167958656, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI2367285, Length=362, Percent_Identity=29.8342541436464, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 46928; Mature: 46797

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAESANASVRTGPAPSSKTREFARAILSGTAVHPEEIPAGRAYTTLRDLATHPGLRDV
CCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCHHHH
TDVLIPGSAPDTVDFLPLARLVNAAELPAIRAAIDSVLPSGKFTSGPHVDAFEDEIATYL
HHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
GIDHVIGASSGTDAMTAVLLALGAGPGTEVILPANSFAATENAVFLTGARPVLVDTRADD
HHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCEEEEECCCCC
HLLDPTEVEAAITSRTVAVLPVHLYGAFADIHALTEVTSRHGIPVVEDGCQGIGLDGLGH
CCCCHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCC
HSDAAILSFNPYKNLGAVGKAGAVATRLPGLARRVTELLYHGFAAGQKNVKAAGYGLNSR
CCCCEEEEECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEECCCCHHH
LDNLQAAVLRARLDWLGENNLARSILARRYVDGLADLAESGLLRLPHWDTDHVWHLFTVE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEE
VTKHDRDKVTESLRAAGVATDLYYPVLTHRHRVPLVADLFEGVRLPRTEAAHARMFQLPL
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHEEEECCC
YPTLTLAEQDRVIGVLHDVLG
CCEEEECCCCHHHHHHHHHHC
>Mature Secondary Structure 
SIAESANASVRTGPAPSSKTREFARAILSGTAVHPEEIPAGRAYTTLRDLATHPGLRDV
CCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCHHHH
TDVLIPGSAPDTVDFLPLARLVNAAELPAIRAAIDSVLPSGKFTSGPHVDAFEDEIATYL
HHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
GIDHVIGASSGTDAMTAVLLALGAGPGTEVILPANSFAATENAVFLTGARPVLVDTRADD
HHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCEEEEECCCCC
HLLDPTEVEAAITSRTVAVLPVHLYGAFADIHALTEVTSRHGIPVVEDGCQGIGLDGLGH
CCCCHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCC
HSDAAILSFNPYKNLGAVGKAGAVATRLPGLARRVTELLYHGFAAGQKNVKAAGYGLNSR
CCCCEEEEECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEECCCCHHH
LDNLQAAVLRARLDWLGENNLARSILARRYVDGLADLAESGLLRLPHWDTDHVWHLFTVE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEE
VTKHDRDKVTESLRAAGVATDLYYPVLTHRHRVPLVADLFEGVRLPRTEAAHARMFQLPL
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHEEEECCC
YPTLTLAEQDRVIGVLHDVLG
CCEEEECCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]