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The map label for this gene is ntdC [H]

Identifier: 169629698

GI number: 169629698

Start: 2650967

End: 2652052

Strand: Direct

Name: ntdC [H]

Synonym: MAB_2612

Alternate gene names: 169629698

Gene position: 2650967-2652052 (Clockwise)

Preceding gene: 169629697

Following gene: 169629699

Centisome position: 52.32

GC content: 63.35

Gene sequence:

>1086_bases
ATGTTGAAAGTCGGAATTATCGGGGCCGGCGGTGTCGCCCGTGCCCACGCTCGCGCGCTGAACACCCTCAAATCTGCCGA
ACTGGTGGGTGTATTGGATATCGATGCCCGGGCCGCCGAGTCCTTCACCGACGCCTACGGCGGTACCCCGGTCACCGATG
TCGATGCGCTGCTGGAACTGGCCGATGCCGTCGTAGTCGCCTCTCCCAACTTTACGCACCGCGACCATTCACTATCGGCA
CTGCGCGCCGGTCGATCGGTGCTGTGCGAGAAGCCACTCGCACTCTCTCGCGTCGAGGCCAAGGAAATGGTGGCGGCCGC
CGGTGAGATCGCCTCCCCCGCACTCGTGGGATTCAACTACCGCCATCTGCCCGTGGTCACTGAGCTGCGCCGCCGACTGC
AGCACGGCGACTTCGGCACGATCTGCGCCGTGGAACTTGGGTTTCGGAAGGACTCCGCATACCGGCGCAAGAACCACACA
TGGCGCGATAGCGGACGTTCCAACGGCACCAGCGGCGCGCTGGGTGATCTCGGCGTGCACCTGCTTGACCTGCTGACCTA
CATCTCCGGCGGCAGAATTCTCGTCGACGAATGCCAAGCCCGGATCACCACTCATGTGACCAACAAGAGCGACGAGGCGG
TCGAGGTCGATGACCATGCGGAGATCTACGGACGCCTCAGCACCGGAAGCATTTTCACGCTCGTGGCCTCCAAAGCCGCG
CCGGCGGCTGACTGCGGATTCTCCATCCGGATCGTTGGCACCAACGCGGTGTTCCGGTACCACACGGCCGATCCGGGGCG
TTATCTAGTTTCCCGCGGTGCCGACACCGAAACCGTTGACTTGGCGCGTACCTTGCTGTCCGATCCGGACAACGAGGTGC
ACGGCTGGTCGGATTCCTTCCGCTCCGAAATCGATCACTGGAGCCGTCTTGTGGCGGTAGGCGGTGGAGCCAACCGACAG
GCCCTCGCGACATTCGATGATGGTTTGGCCGCGCAAGAGGTCTTGGAGTCGCTGCTGCGTGGAAGTAAGCCGCAGCCAGA
GCGCCTGCCGGTCGAGCACACGTTACCGACTCCTGCGGAATTGTGA

Upstream 100 bases:

>100_bases
CTGCCGAGGCGCGCCAGGCCCATCCACACGTCACCGCCCGGCCGCACGCAGGCGGAATCGTCGACACCATCGCCAATATT
CTTACGAAGGAGCAGTAGCC

Downstream 100 bases:

>100_bases
CGCGACGTGACCACGTTCACCTCGCATCGTGCGGTGCCTACGCGGGAGTGGGCACCGCACATGTGTTCTGGGGCACGGTT
TCCCCCTACGCCCTGCCTGC

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLKVGIIGAGGVARAHARALNTLKSAELVGVLDIDARAAESFTDAYGGTPVTDVDALLELADAVVVASPNFTHRDHSLSA
LRAGRSVLCEKPLALSRVEAKEMVAAAGEIASPALVGFNYRHLPVVTELRRRLQHGDFGTICAVELGFRKDSAYRRKNHT
WRDSGRSNGTSGALGDLGVHLLDLLTYISGGRILVDECQARITTHVTNKSDEAVEVDDHAEIYGRLSTGSIFTLVASKAA
PAADCGFSIRIVGTNAVFRYHTADPGRYLVSRGADTETVDLARTLLSDPDNEVHGWSDSFRSEIDHWSRLVAVGGGANRQ
ALATFDDGLAAQEVLESLLRGSKPQPERLPVEHTLPTPAEL

Sequences:

>Translated_361_residues
MLKVGIIGAGGVARAHARALNTLKSAELVGVLDIDARAAESFTDAYGGTPVTDVDALLELADAVVVASPNFTHRDHSLSA
LRAGRSVLCEKPLALSRVEAKEMVAAAGEIASPALVGFNYRHLPVVTELRRRLQHGDFGTICAVELGFRKDSAYRRKNHT
WRDSGRSNGTSGALGDLGVHLLDLLTYISGGRILVDECQARITTHVTNKSDEAVEVDDHAEIYGRLSTGSIFTLVASKAA
PAADCGFSIRIVGTNAVFRYHTADPGRYLVSRGADTETVDLARTLLSDPDNEVHGWSDSFRSEIDHWSRLVAVGGGANRQ
ALATFDDGLAAQEVLESLLRGSKPQPERLPVEHTLPTPAEL
>Mature_361_residues
MLKVGIIGAGGVARAHARALNTLKSAELVGVLDIDARAAESFTDAYGGTPVTDVDALLELADAVVVASPNFTHRDHSLSA
LRAGRSVLCEKPLALSRVEAKEMVAAAGEIASPALVGFNYRHLPVVTELRRRLQHGDFGTICAVELGFRKDSAYRRKNHT
WRDSGRSNGTSGALGDLGVHLLDLLTYISGGRILVDECQARITTHVTNKSDEAVEVDDHAEIYGRLSTGSIFTLVASKAA
PAADCGFSIRIVGTNAVFRYHTADPGRYLVSRGADTETVDLARTLLSDPDNEVHGWSDSFRSEIDHWSRLVAVGGGANRQ
ALATFDDGLAAQEVLESLLRGSKPQPERLPVEHTLPTPAEL

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=195, Percent_Identity=34.3589743589744, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082405, Length=194, Percent_Identity=25.7731958762887, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38650; Mature: 38650

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVGIIGAGGVARAHARALNTLKSAELVGVLDIDARAAESFTDAYGGTPVTDVDALLEL
CEEEEEEECCCHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHH
ADAVVVASPNFTHRDHSLSALRAGRSVLCEKPLALSRVEAKEMVAAAGEIASPALVGFNY
HCEEEEECCCCCCCCCHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECCCC
RHLPVVTELRRRLQHGDFGTICAVELGFRKDSAYRRKNHTWRDSGRSNGTSGALGDLGVH
CCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
LLDLLTYISGGRILVDECQARITTHVTNKSDEAVEVDDHAEIYGRLSTGSIFTLVASKAA
HHHHHHHHCCCEEEEHHHHHHHHHEECCCCCCEEECCCCHHHEEECCCCCEEEEEECCCC
PAADCGFSIRIVGTNAVFRYHTADPGRYLVSRGADTETVDLARTLLSDPDNEVHGWSDSF
CCCCCCEEEEEEECCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHH
RSEIDHWSRLVAVGGGANRQALATFDDGLAAQEVLESLLRGSKPQPERLPVEHTLPTPAE
HHHHHHHHHEEEECCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
L
C
>Mature Secondary Structure
MLKVGIIGAGGVARAHARALNTLKSAELVGVLDIDARAAESFTDAYGGTPVTDVDALLEL
CEEEEEEECCCHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHH
ADAVVVASPNFTHRDHSLSALRAGRSVLCEKPLALSRVEAKEMVAAAGEIASPALVGFNY
HCEEEEECCCCCCCCCHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECCCC
RHLPVVTELRRRLQHGDFGTICAVELGFRKDSAYRRKNHTWRDSGRSNGTSGALGDLGVH
CCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
LLDLLTYISGGRILVDECQARITTHVTNKSDEAVEVDDHAEIYGRLSTGSIFTLVASKAA
HHHHHHHHCCCEEEEHHHHHHHHHEECCCCCCEEECCCCHHHEEECCCCCEEEEEECCCC
PAADCGFSIRIVGTNAVFRYHTADPGRYLVSRGADTETVDLARTLLSDPDNEVHGWSDSF
CCCCCCEEEEEEECCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHH
RSEIDHWSRLVAVGGGANRQALATFDDGLAAQEVLESLLRGSKPQPERLPVEHTLPTPAE
HHHHHHHHHEEEECCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]