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The map label for this gene is cmtR [H]

Identifier: 169629690

GI number: 169629690

Start: 2641649

End: 2641969

Strand: Reverse

Name: cmtR [H]

Synonym: MAB_2604c

Alternate gene names: 169629690

Gene position: 2641969-2641649 (Counterclockwise)

Preceding gene: 169629691

Following gene: 169629689

Centisome position: 52.14

GC content: 64.49

Gene sequence:

>321_bases
GTGGCGACGTTGGTTCATCGTGACGCCCTGACGAGATTCGGATGCGCGCTCTCCGACCCGACCCGGGCCGCGATCCTGCT
GAGCTTGCGGTCACGGCCCGGATATCCGTCCGAACTCGCCGAGGCGGTGGGGGTATCGCGGCAGATAACGTCGAATCACC
TTGCCTGCCTGCGTGGTTGCGGATTGGTTGTTGGGATCGCCGAGGGCCGTCGCACTCGATATGAGCTGGCGGACGAACGA
ATCGGACGAGCCCTGGATGACCTGGTGGACCTGGTGCTGACGGTGGATCCGTCGTACTGCCCAGTGGGCGAGGAATGCTG
A

Upstream 100 bases:

>100_bases
GCCGGCGGGGGCGAAGGCACGCGCGGTTCCCGTCGATACGGCGCCGGCGCCCCATTAGTACATCTAGATCTGAATACAGG
ACAAGCTGTACTATCGGCGC

Downstream 100 bases:

>100_bases
TGGTGCTCGCGCAACAACGGCGAGATGTGCTCAACCGCCGGATCCGGTTCTTTGTCGTTGCCACCATCGCCTACAACGTG
ATCGAGGCCATCGTGGCCCT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MATLVHRDALTRFGCALSDPTRAAILLSLRSRPGYPSELAEAVGVSRQITSNHLACLRGCGLVVGIAEGRRTRYELADER
IGRALDDLVDLVLTVDPSYCPVGEEC

Sequences:

>Translated_106_residues
MATLVHRDALTRFGCALSDPTRAAILLSLRSRPGYPSELAEAVGVSRQITSNHLACLRGCGLVVGIAEGRRTRYELADER
IGRALDDLVDLVLTVDPSYCPVGEEC
>Mature_105_residues
ATLVHRDALTRFGCALSDPTRAAILLSLRSRPGYPSELAEAVGVSRQITSNHLACLRGCGLVVGIAEGRRTRYELADERI
GRALDDLVDLVLTVDPSYCPVGEEC

Specific function: Metal-responsive transcriptional repressor for the cmt operon. Binding of cadmium or lead causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11441; Mature: 11310

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLVHRDALTRFGCALSDPTRAAILLSLRSRPGYPSELAEAVGVSRQITSNHLACLRGC
CCCHHHHHHHHHHCCCCCCCCHHHHHEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHC
GLVVGIAEGRRTRYELADERIGRALDDLVDLVLTVDPSYCPVGEEC
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ATLVHRDALTRFGCALSDPTRAAILLSLRSRPGYPSELAEAVGVSRQITSNHLACLRGC
CCHHHHHHHHHHCCCCCCCCHHHHHEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHC
GLVVGIAEGRRTRYELADERIGRALDDLVDLVLTVDPSYCPVGEEC
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]