| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is fabG [C]
Identifier: 169628499
GI number: 169628499
Start: 1411587
End: 1412420
Strand: Reverse
Name: fabG [C]
Synonym: MAB_1408c
Alternate gene names: 169628499
Gene position: 1412420-1411587 (Counterclockwise)
Preceding gene: 169628500
Following gene: 169628498
Centisome position: 27.87
GC content: 62.83
Gene sequence:
>834_bases GTGGCTGATTTCGAGGGAAAAACTGCACTGATCACGGGCGGCGCGCGCGGTATGGGCCGGTCGCACGCGGTGGCGCTGGC CGAGGCCGGCGCCGATATCGCGATCTGTGATCGCTGTGAGAACAGCGATGTCGTGGGATATCCGCTGGCAACCGCAGACG ACCTCGCCGAGACGGTCGCATTGGTCGAAAAGACCGGACGCCGGTGCATCTCGGCCAAGGTGGACGTGAAGGACCGGGCC GCACTGGAATCGTTTGTGGCCGAGGCCGAGGACACGCTCGGCGGTATCGACATCGCCATCACCAACGCCGGGATCAGCAC CATCGCGCTGCTGCCCGAGGTCGAATCCGCGCAGTGGGACGAGGTTATCGGCACTAACCTCACCGGAACCTTCAATACCA TCGCGGCCGTCGCGCCAGGAATGATCAAACGAAACTACGGCCGCATCGTGACCGTGTCCTCGATGCTCGGCCACAGCGCG AACTTTGCGCAGGCCTCCTACGTGTCGTCCAAATGGGGCGTGATCGGCCTCACCAAATGCGCGGCCCACGATCTCGTCGG CTACGGGATCACTGTCAACGCCGTCGCTCCGGGCAATATCGAAACCCCGATGACGCACAATGATTTCGTATTCGGCACGA TGCGGCCCGATCTGGAGAAACCGACGCTCAAGGACGTGGAGTCCGTGTTCGCGTCCCTGCATCTGCAATATGCCCCCTTC CTCAAACCCGAAGAGGTCACCCGCGCCGTGCTGTTCCTGGTCGACGAGGCGAGCTCACATATCACCGGTACCGTGTTGCC GATCGACGCCGGCGCCACGGCGCGAATGATATGA
Upstream 100 bases:
>100_bases CTGCTCATCGCCATCGCGAGTACTCGGATGCGTGTCTTGCGAGAATTGGACCAGGACGAACCGCAGCCCGACAAGGAACC AACTCGGTAGGGTCGGCTCC
Downstream 100 bases:
>100_bases GCCGGGACGCCCTCCACGCCCTCACCGCCGTCCTCGGTGAGGGCGCCGTCATCACCGATCCCGATATCACCGCCTCGTAC CGGCAGGACCGCGCCTTCGA
Product: putative short-chain dehydrogenase/reductase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 277; Mature: 276
Protein sequence:
>277_residues MADFEGKTALITGGARGMGRSHAVALAEAGADIAICDRCENSDVVGYPLATADDLAETVALVEKTGRRCISAKVDVKDRA ALESFVAEAEDTLGGIDIAITNAGISTIALLPEVESAQWDEVIGTNLTGTFNTIAAVAPGMIKRNYGRIVTVSSMLGHSA NFAQASYVSSKWGVIGLTKCAAHDLVGYGITVNAVAPGNIETPMTHNDFVFGTMRPDLEKPTLKDVESVFASLHLQYAPF LKPEEVTRAVLFLVDEASSHITGTVLPIDAGATARMI
Sequences:
>Translated_277_residues MADFEGKTALITGGARGMGRSHAVALAEAGADIAICDRCENSDVVGYPLATADDLAETVALVEKTGRRCISAKVDVKDRA ALESFVAEAEDTLGGIDIAITNAGISTIALLPEVESAQWDEVIGTNLTGTFNTIAAVAPGMIKRNYGRIVTVSSMLGHSA NFAQASYVSSKWGVIGLTKCAAHDLVGYGITVNAVAPGNIETPMTHNDFVFGTMRPDLEKPTLKDVESVFASLHLQYAPF LKPEEVTRAVLFLVDEASSHITGTVLPIDAGATARMI >Mature_276_residues ADFEGKTALITGGARGMGRSHAVALAEAGADIAICDRCENSDVVGYPLATADDLAETVALVEKTGRRCISAKVDVKDRAA LESFVAEAEDTLGGIDIAITNAGISTIALLPEVESAQWDEVIGTNLTGTFNTIAAVAPGMIKRNYGRIVTVSSMLGHSAN FAQASYVSSKWGVIGLTKCAAHDLVGYGITVNAVAPGNIETPMTHNDFVFGTMRPDLEKPTLKDVESVFASLHLQYAPFL KPEEVTRAVLFLVDEASSHITGTVLPIDAGATARMI
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=272, Percent_Identity=31.25, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI4504505, Length=273, Percent_Identity=31.1355311355311, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI40254992, Length=265, Percent_Identity=29.4339622641509, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI19923817, Length=271, Percent_Identity=26.9372693726937, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI32483357, Length=271, Percent_Identity=30.2583025830258, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI4758504, Length=212, Percent_Identity=30.188679245283, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI4503817, Length=198, Percent_Identity=26.7676767676768, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI59889578, Length=249, Percent_Identity=27.710843373494, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI7705925, Length=267, Percent_Identity=28.4644194756554, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI31542939, Length=269, Percent_Identity=26.0223048327138, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI142976729, Length=208, Percent_Identity=27.8846153846154, Blast_Score=75, Evalue=9e-14, Organism=Homo sapiens, GI83715985, Length=198, Percent_Identity=28.7878787878788, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI210032110, Length=205, Percent_Identity=25.8536585365854, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=28.7878787878788, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI7657478, Length=200, Percent_Identity=29.5, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI66933014, Length=199, Percent_Identity=25.1256281407035, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI44680136, Length=111, Percent_Identity=34.2342342342342, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI44680133, Length=111, Percent_Identity=34.2342342342342, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI17738292, Length=111, Percent_Identity=34.2342342342342, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7706318, Length=211, Percent_Identity=25.1184834123223, Blast_Score=67, Evalue=3e-11, Organism=Homo sapiens, GI126723750, Length=275, Percent_Identity=29.8181818181818, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI5031737, Length=273, Percent_Identity=27.1062271062271, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1787335, Length=269, Percent_Identity=33.457249070632, Blast_Score=137, Evalue=7e-34, Organism=Escherichia coli, GI87082100, Length=276, Percent_Identity=32.2463768115942, Blast_Score=119, Evalue=3e-28, Organism=Escherichia coli, GI87082160, Length=272, Percent_Identity=28.3088235294118, Blast_Score=110, Evalue=9e-26, Organism=Escherichia coli, GI1789208, Length=273, Percent_Identity=28.9377289377289, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1790717, Length=269, Percent_Identity=28.2527881040892, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1786812, Length=275, Percent_Identity=26.1818181818182, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1788459, Length=270, Percent_Identity=30.3703703703704, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1787905, Length=273, Percent_Identity=27.1062271062271, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1789378, Length=200, Percent_Identity=29, Blast_Score=78, Evalue=8e-16, Organism=Escherichia coli, GI2367175, Length=273, Percent_Identity=25.2747252747253, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI2367365, Length=270, Percent_Identity=28.5185185185185, Blast_Score=68, Evalue=8e-13, Organism=Escherichia coli, GI1789057, Length=187, Percent_Identity=25.1336898395722, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787820, Length=152, Percent_Identity=28.9473684210526, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1786701, Length=206, Percent_Identity=27.6699029126214, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI25147288, Length=268, Percent_Identity=30.5970149253731, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17555706, Length=276, Percent_Identity=31.5217391304348, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17568967, Length=224, Percent_Identity=29.9107142857143, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17564282, Length=205, Percent_Identity=30.2439024390244, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17567345, Length=252, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17562990, Length=294, Percent_Identity=30.2721088435374, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17560676, Length=274, Percent_Identity=28.4671532846715, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562910, Length=286, Percent_Identity=28.3216783216783, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17560150, Length=288, Percent_Identity=29.1666666666667, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17562904, Length=288, Percent_Identity=26.7361111111111, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560220, Length=288, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17531453, Length=288, Percent_Identity=27.4305555555556, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17562906, Length=298, Percent_Identity=27.5167785234899, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17561402, Length=275, Percent_Identity=27.6363636363636, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562908, Length=285, Percent_Identity=28.0701754385965, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538486, Length=288, Percent_Identity=29.5138888888889, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI115534694, Length=270, Percent_Identity=27.037037037037, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71982365, Length=198, Percent_Identity=28.7878787878788, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI72000259, Length=279, Percent_Identity=26.1648745519713, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193203115, Length=204, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI193203117, Length=201, Percent_Identity=27.363184079602, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193204405, Length=290, Percent_Identity=26.551724137931, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17551412, Length=283, Percent_Identity=25.7950530035336, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17538182, Length=212, Percent_Identity=27.3584905660377, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17536651, Length=273, Percent_Identity=27.8388278388278, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17563726, Length=280, Percent_Identity=26.0714285714286, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17558628, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17559104, Length=294, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17536025, Length=272, Percent_Identity=27.9411764705882, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17560332, Length=291, Percent_Identity=25.7731958762887, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17544670, Length=282, Percent_Identity=25.177304964539, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71994600, Length=282, Percent_Identity=26.9503546099291, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17508895, Length=205, Percent_Identity=24.390243902439, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI71994604, Length=268, Percent_Identity=25.7462686567164, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17538480, Length=278, Percent_Identity=25.5395683453237, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=273, Percent_Identity=25.6410256410256, Blast_Score=87, Evalue=3e-18, Organism=Saccharomyces cerevisiae, GI6324126, Length=269, Percent_Identity=26.7657992565056, Blast_Score=70, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=26.3681592039801, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI24639444, Length=273, Percent_Identity=30.03663003663, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI18859837, Length=223, Percent_Identity=29.5964125560538, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI24644339, Length=276, Percent_Identity=28.6231884057971, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI28571526, Length=288, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI21357041, Length=280, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=7e-17, Organism=Drosophila melanogaster, GI21355631, Length=185, Percent_Identity=29.1891891891892, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI21355319, Length=280, Percent_Identity=29.2857142857143, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI17737361, Length=209, Percent_Identity=28.7081339712919, Blast_Score=78, Evalue=8e-15, Organism=Drosophila melanogaster, GI24581726, Length=222, Percent_Identity=28.3783783783784, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21357673, Length=196, Percent_Identity=28.0612244897959, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI24665243, Length=259, Percent_Identity=28.1853281853282, Blast_Score=73, Evalue=3e-13, Organism=Drosophila melanogaster, GI221331218, Length=259, Percent_Identity=28.1853281853282, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI23397609, Length=273, Percent_Identity=27.4725274725275, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24665247, Length=260, Percent_Identity=28.0769230769231, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI221331216, Length=260, Percent_Identity=28.0769230769231, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI24644337, Length=291, Percent_Identity=29.553264604811, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 29083; Mature: 28952
Theoretical pI: Translated: 4.59; Mature: 4.59
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADFEGKTALITGGARGMGRSHAVALAEAGADIAICDRCENSDVVGYPLATADDLAETVA CCCCCCCEEEEECCCCCCCCCCEEEEECCCCCEEEECCCCCCCEEECCCCCHHHHHHHHH LVEKTGRRCISAKVDVKDRAALESFVAEAEDTLGGIDIAITNAGISTIALLPEVESAQWD HHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCHH EVIGTNLTGTFNTIAAVAPGMIKRNYGRIVTVSSMLGHSANFAQASYVSSKWGVIGLTKC HHHCCCCCCHHHHHHHHCCHHHHCCCCCEEEEHHHHCCCCCCHHHHHHCCCCCEEEEHHH AAHDLVGYGITVNAVAPGNIETPMTHNDFVFGTMRPDLEKPTLKDVESVFASLHLQYAPF HHHHHEECCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC LKPEEVTRAVLFLVDEASSHITGTVLPIDAGATARMI CCHHHHHHHHHEEEECCCCCEEEEEEEECCCCCCCCC >Mature Secondary Structure ADFEGKTALITGGARGMGRSHAVALAEAGADIAICDRCENSDVVGYPLATADDLAETVA CCCCCCEEEEECCCCCCCCCCEEEEECCCCCEEEECCCCCCCEEECCCCCHHHHHHHHH LVEKTGRRCISAKVDVKDRAALESFVAEAEDTLGGIDIAITNAGISTIALLPEVESAQWD HHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCHH EVIGTNLTGTFNTIAAVAPGMIKRNYGRIVTVSSMLGHSANFAQASYVSSKWGVIGLTKC HHHCCCCCCHHHHHHHHCCHHHHCCCCCEEEEHHHHCCCCCCHHHHHHCCCCCEEEEHHH AAHDLVGYGITVNAVAPGNIETPMTHNDFVFGTMRPDLEKPTLKDVESVFASLHLQYAPF HHHHHEECCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC LKPEEVTRAVLFLVDEASSHITGTVLPIDAGATARMI CCHHHHHHHHHEEEECCCCCEEEEEEEECCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA