BacMap

Definition	Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession	NC_010397
Length	5,067,172

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The map label for this gene is fabG [H]

Identifier: 169628303

GI number: 169628303

Start: 1223145

End: 1223999

Strand: Reverse

Name: fabG [H]

Synonym: MAB_1210c

Alternate gene names: 169628303

Gene position: 1223999-1223145 (Counterclockwise)

Preceding gene: 169628304

Following gene: 169628301

Centisome position: 24.16

GC content: 66.55

Gene sequence:

>855_bases
ATGCCCAATTGTGTTGTCGTTGGGGGTAGCCGGGGCATCGGCCGTGCGGTGGCGCTGCTACTCGGCGAGCTGGGCACCAA
TGTGGTGGTGAACGGCCGTCATGCCGACGTGGTCGACGACACCGTCGGTGCGATCACGTCGAGCGGTGGCACGGCGGTCG
GCTTTGTCGGCGCGCCGGATAACGAGCGGACGGCCACGGATCTGATCGACACCTGCCGCACCCAGTACGGTGGCATCGAT
GCGTTGATCAACTGCGCGGGCATACCCGAACCCACCGGCTCGTCCATCCTCACCATCACCTCCGGCGACTTCCACCGGCT
CATCGACGCACATCTGGGCACCGTGTTCCACACCTGCCGTGTGGTCGCGCCGCTCATGGTTCAGCAGCGACACGGGGCCA
TCATCAACACCGGATCGACTGCTTCCCTAGGGATCTACGGCGGCACGGGATATCCCGCGGGCAAGGCGGCCGTCAACGGA
CTCACGCTGGCGATCGCCGCCGAGCTGAAACGCAGCGGCGTGCGCGCCAACGTGATCTGCCCGGGTGCCCGCACCCGGTT
GTCCGAGGGACCGGAGTACACCGCGCACCTGCACGATCTGCACACCCGGGGATTGCTCGACGACATGACCCTGCAGGCGT
CGTTGGTGCCGGCACCGCCAGCGTGCGTGGCACCGCTGTACGCCTACCTGGCAGGCGATCTGTCTGCCCGCGTCACCGGA
CAGATCTTTCTTGCCGCGGGCGGTTTCATCGGACGTTTCAAGCGCCAGACGCCGGTACCGCTGGGATACCGCGATCACGC
GCTGGACGCACCGTGGTCGATGGAGGAGATCGACGACCTGATGGGCAGACGCTGA

Upstream 100 bases:

>100_bases
TGCCGGACATCTCGCGGATCGGGGATGCGCCCCGGTTCCATTCCGGCTGGATCAACGGGATCAAGAAGTTCGACACGGCG
TACTGCCCCGTCACGCACTG

Downstream 100 bases:

>100_bases
CTACTGCCCAAACCGCCGGTTTCGCGCGGCGTAATCGCGCAGCGCGCGCAGGAAGTCCACCCGCCGGAACTCGGGCCAAT
AGGCGTCGGTGAACCACATC

Product: putative short chain dehydrogenase/reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MPNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPDNERTATDLIDTCRTQYGGID
ALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCRVVAPLMVQQRHGAIINTGSTASLGIYGGTGYPAGKAAVNG
LTLAIAAELKRSGVRANVICPGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYAYLAGDLSARVTG
QIFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLMGRR

Sequences:

>Translated_284_residues
MPNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPDNERTATDLIDTCRTQYGGID
ALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCRVVAPLMVQQRHGAIINTGSTASLGIYGGTGYPAGKAAVNG
LTLAIAAELKRSGVRANVICPGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYAYLAGDLSARVTG
QIFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLMGRR
>Mature_283_residues
PNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPDNERTATDLIDTCRTQYGGIDA
LINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCRVVAPLMVQQRHGAIINTGSTASLGIYGGTGYPAGKAAVNGL
TLAIAAELKRSGVRANVICPGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYAYLAGDLSARVTGQ
IFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLMGRR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=290, Percent_Identity=28.9655172413793, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI40254992, Length=180, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI66933014, Length=188, Percent_Identity=29.7872340425532, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI209862901, Length=190, Percent_Identity=32.6315789473684, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19923983, Length=190, Percent_Identity=32.6315789473684, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503817, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI19923817, Length=187, Percent_Identity=26.7379679144385, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=198, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=27.6264591439689, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=27.0916334661355, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87082160, Length=192, Percent_Identity=29.6875, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367175, Length=188, Percent_Identity=31.9148936170213, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790717, Length=260, Percent_Identity=25.7692307692308, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786812, Length=241, Percent_Identity=28.2157676348548, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=27.710843373494, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=27.027027027027, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=258, Percent_Identity=29.4573643410853, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=28.3524904214559, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=27.906976744186, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=27.2373540856031, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=26.7924528301887, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=264, Percent_Identity=28.030303030303, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=29.9610894941634, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=25, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=258, Percent_Identity=27.1317829457364, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=266, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=28.8973384030418, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=25.5813953488372, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=29.8804780876494, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=26.8939393939394, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=194, Percent_Identity=29.3814432989691, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=26.3358778625954, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=25.1937984496124, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=26.7716535433071, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=181, Percent_Identity=27.6243093922652, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=25.7692307692308, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=186, Percent_Identity=29.5698924731183, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71997099, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=26.9961977186312, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=25.968992248062, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=201, Percent_Identity=28.3582089552239, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=25.2918287937743, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=292, Percent_Identity=30.4794520547945, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859837, Length=293, Percent_Identity=30.3754266211604, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=30.241935483871, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=29.0322580645161, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17737361, Length=195, Percent_Identity=31.2820512820513, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=27.4193548387097, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=23.8461538461538, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 29505; Mature: 29374

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPD
CCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHEECCCCCEEEEEECCC
NERTATDLIDTCRTQYGGIDALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCR
CCCHHHHHHHHHHHHHCCHHHHEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
VVAPLMVQQRHGAIINTGSTASLGIYGGTGYPAGKAAVNGLTLAIAAELKRSGVRANVIC
HHHHHHHHHHCCCEEECCCCCEEEEECCCCCCCCHHHHCCEEEEEEHHHHHCCCEEEEEC
PGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYAYLAGDLSARVTG
CCHHHHCCCCCCHHHHHHHHHHCCCHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEE
QIFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLMGRR
EEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
PNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPD
CCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHEECCCCCEEEEEECCC
NERTATDLIDTCRTQYGGIDALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCR
CCCHHHHHHHHHHHHHCCHHHHEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
VVAPLMVQQRHGAIINTGSTASLGIYGGTGYPAGKAAVNGLTLAIAAELKRSGVRANVIC
HHHHHHHHHHCCCEEECCCCCEEEEECCCCCCCCHHHHCCEEEEEEHHHHHCCCEEEEEC
PGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYAYLAGDLSARVTG
CCHHHHCCCCCCHHHHHHHHHHCCCHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEE
QIFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLMGRR
EEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]