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The map label for this gene is dapA2 [H]

Identifier: 169628142

GI number: 169628142

Start: 1055676

End: 1056563

Strand: Reverse

Name: dapA2 [H]

Synonym: MAB_1047c

Alternate gene names: 169628142

Gene position: 1056563-1055676 (Counterclockwise)

Preceding gene: 169628143

Following gene: 169628141

Centisome position: 20.85

GC content: 63.63

Gene sequence:

>888_bases
ATGACATCCACACCCCAGTTCCACGGAATCATCGCCTACCCGGTCACCCCATTCCTCCCCGATGACACCGTCGACATCGA
CCGGCTCGCCGAGCTCGTGTCCCGGCTCGTGGACGACGGCGCCCACGCCATCGCACCGTTGGGCAGCACCGGCGAGTCCG
CGTATCTCGAGGAGCGCGAGTTCGACGCGGTTGTCGACACCACCGTGGCGGCGGTGAACAAGCGAGTGCCCGTCATCGTC
GGAGCCTCGGATCTGACCACCGCCAACACCATTCGGCGCGCCCGCCACGCCCAGCAGGCCGGCGCCGACGCCGTGATGGT
GCTGCCGATCTCGTACTGGAAACTCAGCGATCGCGAGATCGCTCAGCACTATGCCTCGGTGGCCGCGGCGATCGATATCC
CGTTGATGGCATATAACAACCCCGCCACCAGCGGAGTGGACATGAAACCCGAACTCTTGGTGTCGATGTTCGGCGATATC
GACAACTTCACCATGGTCAAGGAGTCGACGGGCGACCTGAACCGGATGCTCGAGATCAAGCGCCTCACCAATGGATTGCT
GCCCTTCTATAACGGCAGCAATCCATTGGTGCTCGACGCACTCAACGCCGGTGCATCCGGATGGTGCACTGCCGCACCGT
GTCTAGCACCGCAGCCCTGTCTGGATCTGTACGAGGCGGTACGTGCCGGACGCGACGACGATGCCGCGTCCCTCTACACC
GCACTCAAGCCCTTACTGCAATTCATCGTCGCAGGCGGCCTCCCTACTACCGTCAAGGCCGGGCTGGAACTGCAAGGACG
CCCCGTGGGCGATCCGCGACGGCCGTTACTTCCGCTTGATCCCGAGGGCCGGGAGACGCTGAAGGGCATCCTGGCATCGA
CTCCTTAA

Upstream 100 bases:

>100_bases
CCCCCAAGCGCAGCATCGCCAACTTCGCCTACTACGCCCGCACCGCACTCGCCCATCACCCCGAAACCCTCACCCTGCCG
ACGACACAAGGGAATTCCTA

Downstream 100 bases:

>100_bases
TGATAATGGTTATCATTATCATGTGACCACAGCCCAGCTTCTCCCCGTAACCGTGCTCTCCGGATTTCTTGGCGCCGGAA
AAACCACCCTGCTCAACCAC

Product: dihydrodipicolinate synthetase DapA

Products: NA

Alternate protein names: DHDPS 2 [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTSTPQFHGIIAYPVTPFLPDDTVDIDRLAELVSRLVDDGAHAIAPLGSTGESAYLEEREFDAVVDTTVAAVNKRVPVIV
GASDLTTANTIRRARHAQQAGADAVMVLPISYWKLSDREIAQHYASVAAAIDIPLMAYNNPATSGVDMKPELLVSMFGDI
DNFTMVKESTGDLNRMLEIKRLTNGLLPFYNGSNPLVLDALNAGASGWCTAAPCLAPQPCLDLYEAVRAGRDDDAASLYT
ALKPLLQFIVAGGLPTTVKAGLELQGRPVGDPRRPLLPLDPEGRETLKGILASTP

Sequences:

>Translated_295_residues
MTSTPQFHGIIAYPVTPFLPDDTVDIDRLAELVSRLVDDGAHAIAPLGSTGESAYLEEREFDAVVDTTVAAVNKRVPVIV
GASDLTTANTIRRARHAQQAGADAVMVLPISYWKLSDREIAQHYASVAAAIDIPLMAYNNPATSGVDMKPELLVSMFGDI
DNFTMVKESTGDLNRMLEIKRLTNGLLPFYNGSNPLVLDALNAGASGWCTAAPCLAPQPCLDLYEAVRAGRDDDAASLYT
ALKPLLQFIVAGGLPTTVKAGLELQGRPVGDPRRPLLPLDPEGRETLKGILASTP
>Mature_294_residues
TSTPQFHGIIAYPVTPFLPDDTVDIDRLAELVSRLVDDGAHAIAPLGSTGESAYLEEREFDAVVDTTVAAVNKRVPVIVG
ASDLTTANTIRRARHAQQAGADAVMVLPISYWKLSDREIAQHYASVAAAIDIPLMAYNNPATSGVDMKPELLVSMFGDID
NFTMVKESTGDLNRMLEIKRLTNGLLPFYNGSNPLVLDALNAGASGWCTAAPCLAPQPCLDLYEAVRAGRDDDAASLYTA
LKPLLQFIVAGGLPTTVKAGLELQGRPVGDPRRPLLPLDPEGRETLKGILASTP

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=283, Percent_Identity=27.9151943462898, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI13540533, Length=290, Percent_Identity=25.8620689655172, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786463, Length=273, Percent_Identity=29.3040293040293, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87082415, Length=296, Percent_Identity=26.6891891891892, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788823, Length=286, Percent_Identity=28.6713286713287, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789620, Length=287, Percent_Identity=25.0871080139373, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31506; Mature: 31375

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTPQFHGIIAYPVTPFLPDDTVDIDRLAELVSRLVDDGAHAIAPLGSTGESAYLEERE
CCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHH
FDAVVDTTVAAVNKRVPVIVGASDLTTANTIRRARHAQQAGADAVMVLPISYWKLSDREI
HHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEHHEECCHHHH
AQHYASVAAAIDIPLMAYNNPATSGVDMKPELLVSMFGDIDNFTMVKESTGDLNRMLEIK
HHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
RLTNGLLPFYNGSNPLVLDALNAGASGWCTAAPCLAPQPCLDLYEAVRAGRDDDAASLYT
HHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
ALKPLLQFIVAGGLPTTVKAGLELQGRPVGDPRRPLLPLDPEGRETLKGILASTP
HHHHHHHHHHHCCCCHHHHCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TSTPQFHGIIAYPVTPFLPDDTVDIDRLAELVSRLVDDGAHAIAPLGSTGESAYLEERE
CCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHH
FDAVVDTTVAAVNKRVPVIVGASDLTTANTIRRARHAQQAGADAVMVLPISYWKLSDREI
HHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEHHEECCHHHH
AQHYASVAAAIDIPLMAYNNPATSGVDMKPELLVSMFGDIDNFTMVKESTGDLNRMLEIK
HHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
RLTNGLLPFYNGSNPLVLDALNAGASGWCTAAPCLAPQPCLDLYEAVRAGRDDDAASLYT
HHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
ALKPLLQFIVAGGLPTTVKAGLELQGRPVGDPRRPLLPLDPEGRETLKGILASTP
HHHHHHHHHHHCCCCHHHHCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]