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The map label for this gene is yciC [H]

Identifier: 169628141

GI number: 169628141

Start: 1054517

End: 1055653

Strand: Reverse

Name: yciC [H]

Synonym: MAB_1046c

Alternate gene names: 169628141

Gene position: 1055653-1054517 (Counterclockwise)

Preceding gene: 169628142

Following gene: 169628139

Centisome position: 20.83

GC content: 64.56

Gene sequence:

>1137_bases
GTGACCACAGCCCAGCTTCTCCCCGTAACCGTGCTCTCCGGATTTCTTGGCGCCGGAAAAACCACCCTGCTCAACCACAT
CCTGGCCAACACCGAGGGACGCCGTGTCGCGGTGATCGTCAACGATATGAGCGAGGTGAACATCGACGCCGCCCTCGTTG
CGGGCACCGGCCACCTGGACCGCACCGAGGAGCGGCTCGTCGAGCTCACCAACGGCTGCATCTGCTGCACCTTGCGCGAG
GATCTGATCGAAGCCGTCGGAAACCTGGCCCGACAGAACCGATTTGACCAGCTCGTTATCGAGTCGACCGGAATCTCCGA
GCCCATGCCGGTGGCCGCGTCGTTCACCTGGGAATTCGAGGATGGGACCAGCCTGGGACAGGTCGCACGACTGGACACCA
TGGTGACGGTCGTTGACGCGTCCACCTTTCTCCCCGAGCTGGCCCGCGGCGAGTCGCTCGCCGACCGGGAGATGGCCGCC
GCGAATGGCGACGGACGCTCCATCGCCGACCTACTCACCGACCAGGTGGAATTCGCCGACGTCCTGATCCTCAACAAGGT
GGACCTGGTGAACGAGCGGACGCTCGGAATGGTGGAAACTCTGCTGCGCCGGCTCAATCCCACGGCGACGATCGTGCGGT
CCACCGCTGGCGTCGTCGACCTGGACCTGGTGCTACAGACCGGATTGTTCGATCCCGACCTCGCCGCCCAGACGCCCGGC
TGGGATGAGGAAATCGCCGACGGGCACACCCCCGAAACCGAGGAATACGGCATCAGCAGCATGACCTTCCGCTCGGATCG
CCCGTTCCATCCGCACCGCCTCAACACGGCGCTGGAAAACATGCAGGGACTACTACGCAGCAAGGGGTTCTGCTGGATCG
CGAGCCGCGACGATATCGCCGCGATCTGGTCGCAAGCCGGCCCCAACCTGACCATCGAACCCGCTCAGTTCTGGCACAGC
ACCGAAATCGCACCCGGGCAGGAAATTGTTTTCATCGGCGTCCGCCTGGACCGGCCCCGCGTACAACATCTCCTGGAATC
CGCGGTACTCACCGACGACGAACTCGCCGGGGGGCCCGAGCTGTGGCGTAGCTTCACCGATCCCCTCCCCGCCTGGGGCG
TCATGCACGCTCATTAG

Upstream 100 bases:

>100_bases
GATCCGCGACGGCCGTTACTTCCGCTTGATCCCGAGGGCCGGGAGACGCTGAAGGGCATCCTGGCATCGACTCCTTAATG
ATAATGGTTATCATTATCAT

Downstream 100 bases:

>100_bases
CCCCGGCGGCCCAGCGCCGCCTTCTTGGCCCTGTTCCCGCAGGTGTTCATGTTGCACCAGCGCCGATTGTTGGCCCGGCT
GGTATCGACATACAGGCCAT

Product: cobalamin synthesis protein P47K/CobW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTTAQLLPVTVLSGFLGAGKTTLLNHILANTEGRRVAVIVNDMSEVNIDAALVAGTGHLDRTEERLVELTNGCICCTLRE
DLIEAVGNLARQNRFDQLVIESTGISEPMPVAASFTWEFEDGTSLGQVARLDTMVTVVDASTFLPELARGESLADREMAA
ANGDGRSIADLLTDQVEFADVLILNKVDLVNERTLGMVETLLRRLNPTATIVRSTAGVVDLDLVLQTGLFDPDLAAQTPG
WDEEIADGHTPETEEYGISSMTFRSDRPFHPHRLNTALENMQGLLRSKGFCWIASRDDIAAIWSQAGPNLTIEPAQFWHS
TEIAPGQEIVFIGVRLDRPRVQHLLESAVLTDDELAGGPELWRSFTDPLPAWGVMHAH

Sequences:

>Translated_378_residues
MTTAQLLPVTVLSGFLGAGKTTLLNHILANTEGRRVAVIVNDMSEVNIDAALVAGTGHLDRTEERLVELTNGCICCTLRE
DLIEAVGNLARQNRFDQLVIESTGISEPMPVAASFTWEFEDGTSLGQVARLDTMVTVVDASTFLPELARGESLADREMAA
ANGDGRSIADLLTDQVEFADVLILNKVDLVNERTLGMVETLLRRLNPTATIVRSTAGVVDLDLVLQTGLFDPDLAAQTPG
WDEEIADGHTPETEEYGISSMTFRSDRPFHPHRLNTALENMQGLLRSKGFCWIASRDDIAAIWSQAGPNLTIEPAQFWHS
TEIAPGQEIVFIGVRLDRPRVQHLLESAVLTDDELAGGPELWRSFTDPLPAWGVMHAH
>Mature_377_residues
TTAQLLPVTVLSGFLGAGKTTLLNHILANTEGRRVAVIVNDMSEVNIDAALVAGTGHLDRTEERLVELTNGCICCTLRED
LIEAVGNLARQNRFDQLVIESTGISEPMPVAASFTWEFEDGTSLGQVARLDTMVTVVDASTFLPELARGESLADREMAAA
NGDGRSIADLLTDQVEFADVLILNKVDLVNERTLGMVETLLRRLNPTATIVRSTAGVVDLDLVLQTGLFDPDLAAQTPGW
DEEIADGHTPETEEYGISSMTFRSDRPFHPHRLNTALENMQGLLRSKGFCWIASRDDIAAIWSQAGPNLTIEPAQFWHST
EIAPGQEIVFIGVRLDRPRVQHLLESAVLTDDELAGGPELWRSFTDPLPAWGVMHAH

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI148727351, Length=280, Percent_Identity=31.4285714285714, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI146231952, Length=280, Percent_Identity=31.7857142857143, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI33469141, Length=280, Percent_Identity=31.4285714285714, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI126722884, Length=280, Percent_Identity=31.4285714285714, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI223941779, Length=210, Percent_Identity=33.8095238095238, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI223941776, Length=270, Percent_Identity=31.1111111111111, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI119120938, Length=164, Percent_Identity=35.3658536585366, Blast_Score=102, Evalue=8e-22,
Organism=Escherichia coli, GI87082430, Length=354, Percent_Identity=30.7909604519774, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788499, Length=216, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6324356, Length=212, Percent_Identity=29.2452830188679, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 41273; Mature: 41142

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAQLLPVTVLSGFLGAGKTTLLNHILANTEGRRVAVIVNDMSEVNIDAALVAGTGHLD
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCC
RTEERLVELTNGCICCTLREDLIEAVGNLARQNRFDQLVIESTGISEPMPVAASFTWEFE
HHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCEEEEEEEEC
DGTSLGQVARLDTMVTVVDASTFLPELARGESLADREMAAANGDGRSIADLLTDQVEFAD
CCCCHHHHHHHHHHEEEHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VLILNKVDLVNERTLGMVETLLRRLNPTATIVRSTAGVVDLDLVLQTGLFDPDLAAQTPG
HHEECCHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCCEEEHHHHHHCCCCCCCCCCCCCC
WDEEIADGHTPETEEYGISSMTFRSDRPFHPHRLNTALENMQGLLRSKGFCWIASRDDIA
CCHHHCCCCCCCCHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHH
AIWSQAGPNLTIEPAQFWHSTEIAPGQEIVFIGVRLDRPRVQHLLESAVLTDDELAGGPE
HHHHCCCCCEEECHHHHHCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHCCCHHCCCCHH
LWRSFTDPLPAWGVMHAH
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TTAQLLPVTVLSGFLGAGKTTLLNHILANTEGRRVAVIVNDMSEVNIDAALVAGTGHLD
CCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCC
RTEERLVELTNGCICCTLREDLIEAVGNLARQNRFDQLVIESTGISEPMPVAASFTWEFE
HHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCEEEEEEEEC
DGTSLGQVARLDTMVTVVDASTFLPELARGESLADREMAAANGDGRSIADLLTDQVEFAD
CCCCHHHHHHHHHHEEEHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VLILNKVDLVNERTLGMVETLLRRLNPTATIVRSTAGVVDLDLVLQTGLFDPDLAAQTPG
HHEECCHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCCEEEHHHHHHCCCCCCCCCCCCCC
WDEEIADGHTPETEEYGISSMTFRSDRPFHPHRLNTALENMQGLLRSKGFCWIASRDDIA
CCHHHCCCCCCCCHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHH
AIWSQAGPNLTIEPAQFWHSTEIAPGQEIVFIGVRLDRPRVQHLLESAVLTDDELAGGPE
HHHHCCCCCEEECHHHHHCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHCCCHHCCCCHH
LWRSFTDPLPAWGVMHAH
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]