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The map label for this gene is fucA [H]

Identifier: 169628143

GI number: 169628143

Start: 1056563

End: 1057369

Strand: Reverse

Name: fucA [H]

Synonym: MAB_1048c

Alternate gene names: 169628143

Gene position: 1057369-1056563 (Counterclockwise)

Preceding gene: 169628145

Following gene: 169628142

Centisome position: 20.87

GC content: 64.56

Gene sequence:

>807_bases
ATGGCCAGCACCCTTCACGACACCAAATCCGAACTGATGGATCGTGCCGAGCGCAGCATGCAGACCCACTTCTCCGACTC
GCAATGGACCACCCGCCAGAAGGTGGCGCTGACATGCCGAGCGCTCTTCGACCGGGGCCACGATTCCGGCCTCGCCGGAC
AAATCACCGCGCGCGCCGAGGAACCCGGCACCTTCTACACCCAGCGACTGGGCCTGGGATTCGACGAGATCACCGAGGAG
AACCTGCTTCTCGTCGACGAGGATCTCAACGTTCTCGAAGGCTCAGGAATGGCCAACCCCGCCAATCGCTTCCACAGCTG
GATCTACCGGGCTCGTCCGGACGTGCAGTGCATCGTGCACACCCATCCGTTCCACGTCGCCGCACTGTCCATGCTGGAGA
CGCCACTGATCGTCTCGCAGATGGACATCGCGCCGCTGTACGACGACTGCGCCTTCCTGCCGGACTGGCCAGGCGTTCCC
GTCGGCAACGAGGAGGGCGAAATCATTTCCGCCGCACTCGGAGACAAGAAGGCGATCCTGCTCGCCCACCACGGTCACGT
CGTCGCGGGCGCTTCCGTCGAAGAGTCCTGCTCGCTGGCGGTGTTGATAGAGAGAGGCGCCAAGCTGCAACTGGCCGCGA
TGGCGGCGGGAACCATCGCGCCGCTGCCCGACCGGCTAGCCCGCGAGGCGCATGACTGGACCCTTACCCCCAAGCGCAGC
ATCGCCAACTTCGCCTACTACGCCCGCACCGCACTCGCCCATCACCCCGAAACCCTCACCCTGCCGACGACACAAGGGAA
TTCCTAA

Upstream 100 bases:

>100_bases
ACGAGGTGTCCGCGGCGTTCGCGATGCAACACTGTTGACGATATGACACCTTGTGTCCTATCGTGATGTCCACCCACCGA
GACCAGAAAGGAGCACGAAA

Downstream 100 bases:

>100_bases
TGACATCCACACCCCAGTTCCACGGAATCATCGCCTACCCGGTCACCCCATTCCTCCCCGATGACACCGTCGACATCGAC
CGGCTCGCCGAGCTCGTGTC

Product: class II aldolase/adducin domain protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MASTLHDTKSELMDRAERSMQTHFSDSQWTTRQKVALTCRALFDRGHDSGLAGQITARAEEPGTFYTQRLGLGFDEITEE
NLLLVDEDLNVLEGSGMANPANRFHSWIYRARPDVQCIVHTHPFHVAALSMLETPLIVSQMDIAPLYDDCAFLPDWPGVP
VGNEEGEIISAALGDKKAILLAHHGHVVAGASVEESCSLAVLIERGAKLQLAAMAAGTIAPLPDRLAREAHDWTLTPKRS
IANFAYYARTALAHHPETLTLPTTQGNS

Sequences:

>Translated_268_residues
MASTLHDTKSELMDRAERSMQTHFSDSQWTTRQKVALTCRALFDRGHDSGLAGQITARAEEPGTFYTQRLGLGFDEITEE
NLLLVDEDLNVLEGSGMANPANRFHSWIYRARPDVQCIVHTHPFHVAALSMLETPLIVSQMDIAPLYDDCAFLPDWPGVP
VGNEEGEIISAALGDKKAILLAHHGHVVAGASVEESCSLAVLIERGAKLQLAAMAAGTIAPLPDRLAREAHDWTLTPKRS
IANFAYYARTALAHHPETLTLPTTQGNS
>Mature_267_residues
ASTLHDTKSELMDRAERSMQTHFSDSQWTTRQKVALTCRALFDRGHDSGLAGQITARAEEPGTFYTQRLGLGFDEITEEN
LLLVDEDLNVLEGSGMANPANRFHSWIYRARPDVQCIVHTHPFHVAALSMLETPLIVSQMDIAPLYDDCAFLPDWPGVPV
GNEEGEIISAALGDKKAILLAHHGHVVAGASVEESCSLAVLIERGAKLQLAAMAAGTIAPLPDRLAREAHDWTLTPKRSI
ANFAYYARTALAHHPETLTLPTTQGNS

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=191, Percent_Identity=28.2722513089005, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71989560, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71989541, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71989550, Length=202, Percent_Identity=28.7128712871287, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71989544, Length=202, Percent_Identity=28.7128712871287, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71989555, Length=202, Percent_Identity=28.7128712871287, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI115533216, Length=201, Percent_Identity=26.3681592039801, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115533218, Length=201, Percent_Identity=26.3681592039801, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281363763, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281363757, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17136738, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281363755, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI281363751, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24655690, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24655685, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI281363761, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363759, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363753, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 29302; Mature: 29171

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTLHDTKSELMDRAERSMQTHFSDSQWTTRQKVALTCRALFDRGHDSGLAGQITARAE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
EPGTFYTQRLGLGFDEITEENLLLVDEDLNVLEGSGMANPANRFHSWIYRARPDVQCIVH
CCCCHHHHHHCCCHHHHCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHCCCCCEEEEE
THPFHVAALSMLETPLIVSQMDIAPLYDDCAFLPDWPGVPVGNEEGEIISAALGDKKAIL
CCCHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEE
LAHHGHVVAGASVEESCSLAVLIERGAKLQLAAMAAGTIAPLPDRLAREAHDWTLTPKRS
EEECCCEEECCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCHHH
IANFAYYARTALAHHPETLTLPTTQGNS
HHHHHHHHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure 
ASTLHDTKSELMDRAERSMQTHFSDSQWTTRQKVALTCRALFDRGHDSGLAGQITARAE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
EPGTFYTQRLGLGFDEITEENLLLVDEDLNVLEGSGMANPANRFHSWIYRARPDVQCIVH
CCCCHHHHHHCCCHHHHCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHCCCCCEEEEE
THPFHVAALSMLETPLIVSQMDIAPLYDDCAFLPDWPGVPVGNEEGEIISAALGDKKAIL
CCCHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEE
LAHHGHVVAGASVEESCSLAVLIERGAKLQLAAMAAGTIAPLPDRLAREAHDWTLTPKRS
EEECCCEEECCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCHHH
IANFAYYARTALAHHPETLTLPTTQGNS
HHHHHHHHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]