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The map label for this gene is 169627936

Identifier: 169627936

GI number: 169627936

Start: 832154

End: 833308

Strand: Reverse

Name: 169627936

Synonym: MAB_0837c

Alternate gene names: NA

Gene position: 833308-832154 (Counterclockwise)

Preceding gene: 169627937

Following gene: 169627935

Centisome position: 16.45

GC content: 66.23

Gene sequence:

>1155_bases
ATGAGCCGCGGTGTCGCCGTCGTCGGTGTCGGGCAAAGCAAGCAAGCCAAAAAACGTGAGGTGACCATCGCCGCGCTGGT
CCGCGAAGCGGTGGACGGGGCGCTGGCCGACGCCGAGCTGACCTTCGGCGACATAGACGCGATCGTGCTGGCCAAGACAC
CCGATCTATTCGACGGCGTCATGAACCCGGAGCTGTACCTCGCCGACGCGATCGGCGCGCGGGGTCTGCCGGTCACGCGC
GTATTCACCGGTGGCAGCGTCGGCGGTCACGCCGCCATCTACGCCGCGCACCTGATCCAGGCCCGGCTGGCCGGACGGGT
ATTGGTGGTCGCATATTCCAAAGAGTCCGAGGGCAATTTCACGTGGGCACTGTCACGTCCGTTGCCATTCAGTGCCCAGT
TGGGAGCGGGCGCCGGCGGCCACTTCGCACCGGTGATCCGGGAGTACATCCGCCGCTCGCACGCACCGGAACATATCGGC
TGGCAGGTGGCGGTGAATCACCGCCTCAACGCCACCCGGAACCCCTACGCGCATATCCACAAACCCGATATCACCATCGA
GGAGGTGCGCAACTCCCCGATGCTGTGGGACCCGATCCGATTCCTGGAGTCGTGCCCGTCCTCGGATGGCTCATGTGCCG
TCGTGATTTCTTCGGAGATGCATGCGCGGCTCGCTCCCCGACCGCCGGCCTGGATTCATGGCACCGGATGGCGCACCGAA
ACAGGACATTTCGCGGGCCGAGACGAAGTGAACCCGCGCGCCGGACAGGAGTGCGCCGCCGCCGCGTATCGCGAGGCGGG
CATCACCGATCCCGGCACCGAAGTGGATGTCTCCGAGCTCTACATTCCCTACAGCTGGTATGAGCCGATGTGGATGGAGA
ACATCGGTCTGGCACCGGAGAGTTCGGGCTGGCGCGCCGTCGATGAGGGCCACACCGCATTCGGGGGCCGGCACCCGATC
AACCCGTCCGGAGGCGTGCTCTCCGGCAATCCGACCGGTGCCACCGGCCTACTCCGATTCGCCGAGGCCGCCCTGCAGGT
GCGGGGGCTCGCGGGTGAACACCAGGTCGATGGAGCCAGACGTGCGATAGGCCACGCCATGGGCGGGGCGTCACAGTTCC
ACGCGTTGTGGGTGGTGGGAAGTGAGAAACCATGA

Upstream 100 bases:

>100_bases
CCCGCACCATCATGCAGGGACGCGCCACCCGCGCACTGGCGCACGCTACCAATGGCCCTGCACTGCAGCACAACCTGGTG
TGCTTGATGGAAACAAGCGC

Downstream 100 bases:

>100_bases
GCGCAGCACGAGAACTCCTTGTCGAACGCGACGGGCCGGTCGTTATCCTGACGATGAACCGCCCGCACCGGAGAAATGCC
CTGTCCACCAACATGGTCAG

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSRGVAVVGVGQSKQAKKREVTIAALVREAVDGALADAELTFGDIDAIVLAKTPDLFDGVMNPELYLADAIGARGLPVTR
VFTGGSVGGHAAIYAAHLIQARLAGRVLVVAYSKESEGNFTWALSRPLPFSAQLGAGAGGHFAPVIREYIRRSHAPEHIG
WQVAVNHRLNATRNPYAHIHKPDITIEEVRNSPMLWDPIRFLESCPSSDGSCAVVISSEMHARLAPRPPAWIHGTGWRTE
TGHFAGRDEVNPRAGQECAAAAYREAGITDPGTEVDVSELYIPYSWYEPMWMENIGLAPESSGWRAVDEGHTAFGGRHPI
NPSGGVLSGNPTGATGLLRFAEAALQVRGLAGEHQVDGARRAIGHAMGGASQFHALWVVGSEKP

Sequences:

>Translated_384_residues
MSRGVAVVGVGQSKQAKKREVTIAALVREAVDGALADAELTFGDIDAIVLAKTPDLFDGVMNPELYLADAIGARGLPVTR
VFTGGSVGGHAAIYAAHLIQARLAGRVLVVAYSKESEGNFTWALSRPLPFSAQLGAGAGGHFAPVIREYIRRSHAPEHIG
WQVAVNHRLNATRNPYAHIHKPDITIEEVRNSPMLWDPIRFLESCPSSDGSCAVVISSEMHARLAPRPPAWIHGTGWRTE
TGHFAGRDEVNPRAGQECAAAAYREAGITDPGTEVDVSELYIPYSWYEPMWMENIGLAPESSGWRAVDEGHTAFGGRHPI
NPSGGVLSGNPTGATGLLRFAEAALQVRGLAGEHQVDGARRAIGHAMGGASQFHALWVVGSEKP
>Mature_383_residues
SRGVAVVGVGQSKQAKKREVTIAALVREAVDGALADAELTFGDIDAIVLAKTPDLFDGVMNPELYLADAIGARGLPVTRV
FTGGSVGGHAAIYAAHLIQARLAGRVLVVAYSKESEGNFTWALSRPLPFSAQLGAGAGGHFAPVIREYIRRSHAPEHIGW
QVAVNHRLNATRNPYAHIHKPDITIEEVRNSPMLWDPIRFLESCPSSDGSCAVVISSEMHARLAPRPPAWIHGTGWRTET
GHFAGRDEVNPRAGQECAAAAYREAGITDPGTEVDVSELYIPYSWYEPMWMENIGLAPESSGWRAVDEGHTAFGGRHPIN
PSGGVLSGNPTGATGLLRFAEAALQVRGLAGEHQVDGARRAIGHAMGGASQFHALWVVGSEKP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=392, Percent_Identity=30.1020408163265, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI302344760, Length=322, Percent_Identity=30.7453416149068, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI302344767, Length=317, Percent_Identity=30.9148264984227, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI302344762, Length=289, Percent_Identity=30.7958477508651, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI55956775, Length=257, Percent_Identity=28.7937743190661, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17537653, Length=395, Percent_Identity=26.5822784810127, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24585051, Length=407, Percent_Identity=28.5012285012285, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI19921506, Length=407, Percent_Identity=27.5184275184275, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 40975; Mature: 40843

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRGVAVVGVGQSKQAKKREVTIAALVREAVDGALADAELTFGDIDAIVLAKTPDLFDGV
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHCCCEEEECCCCEEEEECCCHHHHHC
MNPELYLADAIGARGLPVTRVFTGGSVGGHAAIYAAHLIQARLAGRVLVVAYSKESEGNF
CCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCE
TWALSRPLPFSAQLGAGAGGHFAPVIREYIRRSHAPEHIGWQVAVNHRLNATRNPYAHIH
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEE
KPDITIEEVRNSPMLWDPIRFLESCPSSDGSCAVVISSEMHARLAPRPPAWIHGTGWRTE
CCCCCHHHHCCCCCEEHHHHHHHHCCCCCCCEEEEEECCCHHCCCCCCCCEEECCCCCCC
TGHFAGRDEVNPRAGQECAAAAYREAGITDPGTEVDVSELYIPYSWYEPMWMENIGLAPE
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCCCHHHHHCCCCCC
SSGWRAVDEGHTAFGGRHPINPSGGVLSGNPTGATGLLRFAEAALQVRGLAGEHQVDGAR
CCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHH
RAIGHAMGGASQFHALWVVGSEKP
HHHHHHHCCCCCEEEEEEEECCCC
>Mature Secondary Structure 
SRGVAVVGVGQSKQAKKREVTIAALVREAVDGALADAELTFGDIDAIVLAKTPDLFDGV
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHCCCEEEECCCCEEEEECCCHHHHHC
MNPELYLADAIGARGLPVTRVFTGGSVGGHAAIYAAHLIQARLAGRVLVVAYSKESEGNF
CCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCE
TWALSRPLPFSAQLGAGAGGHFAPVIREYIRRSHAPEHIGWQVAVNHRLNATRNPYAHIH
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEE
KPDITIEEVRNSPMLWDPIRFLESCPSSDGSCAVVISSEMHARLAPRPPAWIHGTGWRTE
CCCCCHHHHCCCCCEEHHHHHHHHCCCCCCCEEEEEECCCHHCCCCCCCCEEECCCCCCC
TGHFAGRDEVNPRAGQECAAAAYREAGITDPGTEVDVSELYIPYSWYEPMWMENIGLAPE
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCCCHHHHHCCCCCC
SSGWRAVDEGHTAFGGRHPINPSGGVLSGNPTGATGLLRFAEAALQVRGLAGEHQVDGAR
CCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHH
RAIGHAMGGASQFHALWVVGSEKP
HHHHHHHCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]