| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is yngF [H]
Identifier: 169627935
GI number: 169627935
Start: 831372
End: 832157
Strand: Reverse
Name: yngF [H]
Synonym: MAB_0836c
Alternate gene names: 169627935
Gene position: 832157-831372 (Counterclockwise)
Preceding gene: 169627936
Following gene: 169627934
Centisome position: 16.42
GC content: 64.76
Gene sequence:
>786_bases ATGAGCGCAGCACGAGAACTCCTTGTCGAACGCGACGGGCCGGTCGTTATCCTGACGATGAACCGCCCGCACCGGAGAAA TGCCCTGTCCACCAACATGGTCAGCCAATTCGCCGCGGCCTGGGACGAGATCGACCACGATGACGGCATTCGGGCCGCGA TCCTCACGGGTGCCGGCTCCGCCTATTGCGTGGGAGGTGACCTGAGTGACGGCTGGATGGTGCGGGACGGCTCGGCGCCA CCGCTTGATCCGGCCACCATCGGGAAGGGGCTGCTCCTGAGCCACACCCTCACTAAGCCCCTTATCGCCGCGGTCAACGG CGCATGCCTCGGCGGTGGTTGCGAAATGTTGCAGCAGACCGACATCCGGGTTTCCGATGAGCACGCTACCTTTGGCTTAC CCGAGGTACAGCGCGGCTTGGTGCCCGGTGCCGGATCGATGGTCAGGCTCAAGCGACAGATTCCGTATACCAAGGCCATG GAGATGATCCTGACCGGCGAGCCGCTCACCGCCTTCGAGGCATACCATTTCGGGCTGGTCGGACATGTGGTGCCCGCGGG TACCGCACTGGACAAAGCACGCAGCCTCGCCGACCGGATCGTCCGCAACGGCCCGCTGGCCGTGCGCAATGCCAAAGAAG CGATTGTCCGCAGCGGATGGCTGGCCGAGGAAGACGCCCGTGCCATCGAGGCGAGGCTCACTCGCCCGGTAATCACCTCC GCCGACGCACGCGAGGGATTGGCCGCGTTCAAGGAGAAGCGAGAGGCACGGTTTACCGGGAGATGA
Upstream 100 bases:
>100_bases CGGGTGAACACCAGGTCGATGGAGCCAGACGTGCGATAGGCCACGCCATGGGCGGGGCGTCACAGTTCCACGCGTTGTGG GTGGTGGGAAGTGAGAAACC
Downstream 100 bases:
>100_bases CCGACACGTCGGCTGAAACAACCATCCTCACAGAGGATTCCACCGACCAGCGACTGCTCAATGCCGCCGAACGGCTCTTC GCCGAACGTGGGGTGGATGC
Product: putative enoyl-CoA hydratase/isomerase
Products: trans-2-enoyl-CoA; trans-3-enoyl-CoA; H2O
Alternate protein names: NA
Number of amino acids: Translated: 261; Mature: 260
Protein sequence:
>261_residues MSAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEIDHDDGIRAAILTGAGSAYCVGGDLSDGWMVRDGSAP PLDPATIGKGLLLSHTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRGLVPGAGSMVRLKRQIPYTKAM EMILTGEPLTAFEAYHFGLVGHVVPAGTALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVITS ADAREGLAAFKEKREARFTGR
Sequences:
>Translated_261_residues MSAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEIDHDDGIRAAILTGAGSAYCVGGDLSDGWMVRDGSAP PLDPATIGKGLLLSHTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRGLVPGAGSMVRLKRQIPYTKAM EMILTGEPLTAFEAYHFGLVGHVVPAGTALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVITS ADAREGLAAFKEKREARFTGR >Mature_260_residues SAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEIDHDDGIRAAILTGAGSAYCVGGDLSDGWMVRDGSAPP LDPATIGKGLLLSHTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRGLVPGAGSMVRLKRQIPYTKAME MILTGEPLTAFEAYHFGLVGHVVPAGTALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVITSA DAREGLAAFKEKREARFTGR
Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=32.258064516129, Blast_Score=140, Evalue=9e-34, Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=1e-22, Organism=Homo sapiens, GI150378541, Length=255, Percent_Identity=31.7647058823529, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI70995211, Length=257, Percent_Identity=29.1828793774319, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI25453481, Length=264, Percent_Identity=26.5151515151515, Blast_Score=88, Evalue=9e-18, Organism=Homo sapiens, GI51538573, Length=264, Percent_Identity=26.5151515151515, Blast_Score=88, Evalue=9e-18, Organism=Homo sapiens, GI4757968, Length=261, Percent_Identity=26.8199233716475, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI49355787, Length=261, Percent_Identity=26.8199233716475, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI20127408, Length=186, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI4757966, Length=253, Percent_Identity=26.8774703557312, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI51538581, Length=253, Percent_Identity=26.8774703557312, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI31542718, Length=246, Percent_Identity=27.6422764227642, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI45643119, Length=253, Percent_Identity=27.6679841897233, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI260275230, Length=253, Percent_Identity=27.6679841897233, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI260274832, Length=253, Percent_Identity=27.6679841897233, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI37594469, Length=194, Percent_Identity=29.8969072164948, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI37594471, Length=194, Percent_Identity=29.8969072164948, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI221136756, Length=261, Percent_Identity=25.6704980842912, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI221136753, Length=261, Percent_Identity=25.6704980842912, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI68989263, Length=243, Percent_Identity=27.5720164609054, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI221307494, Length=261, Percent_Identity=25.6704980842912, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI213417737, Length=228, Percent_Identity=25.8771929824561, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI157694516, Length=228, Percent_Identity=25.8771929824561, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=37.0656370656371, Blast_Score=160, Evalue=1e-40, Organism=Escherichia coli, GI221142681, Length=267, Percent_Identity=35.5805243445693, Blast_Score=134, Evalue=7e-33, Organism=Escherichia coli, GI1787660, Length=250, Percent_Identity=32.8, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1788682, Length=205, Percent_Identity=34.6341463414634, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1788597, Length=255, Percent_Identity=27.843137254902, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI87082183, Length=254, Percent_Identity=27.5590551181102, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1790281, Length=196, Percent_Identity=29.5918367346939, Blast_Score=79, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17554946, Length=247, Percent_Identity=34.0080971659919, Blast_Score=143, Evalue=7e-35, Organism=Caenorhabditis elegans, GI25145438, Length=245, Percent_Identity=34.6938775510204, Blast_Score=142, Evalue=1e-34, Organism=Caenorhabditis elegans, GI17540714, Length=221, Percent_Identity=37.10407239819, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17560910, Length=260, Percent_Identity=28.0769230769231, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17549921, Length=221, Percent_Identity=31.2217194570136, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17536985, Length=277, Percent_Identity=25.6317689530686, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI25144157, Length=193, Percent_Identity=30.5699481865285, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI25144160, Length=193, Percent_Identity=30.5699481865285, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17535521, Length=256, Percent_Identity=27.34375, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17558304, Length=238, Percent_Identity=26.0504201680672, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17534483, Length=214, Percent_Identity=26.6355140186916, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17508951, Length=241, Percent_Identity=26.1410788381743, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17508953, Length=241, Percent_Identity=26.1410788381743, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI25144276, Length=241, Percent_Identity=26.1410788381743, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17540306, Length=263, Percent_Identity=27.3764258555133, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI20129971, Length=245, Percent_Identity=36.734693877551, Blast_Score=152, Evalue=2e-37, Organism=Drosophila melanogaster, GI24653477, Length=245, Percent_Identity=36.734693877551, Blast_Score=152, Evalue=2e-37, Organism=Drosophila melanogaster, GI24653139, Length=267, Percent_Identity=36.7041198501873, Blast_Score=136, Evalue=1e-32, Organism=Drosophila melanogaster, GI21357171, Length=263, Percent_Identity=27.3764258555133, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI24650670, Length=264, Percent_Identity=28.4090909090909, Blast_Score=107, Evalue=5e-24, Organism=Drosophila melanogaster, GI24654903, Length=184, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI19920382, Length=229, Percent_Identity=30.1310043668122, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI19922422, Length=254, Percent_Identity=24.0157480314961, Blast_Score=70, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: 4.2.1.17
Molecular weight: Translated: 27930; Mature: 27799
Theoretical pI: Translated: 7.60; Mature: 7.60
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEIDHDDGIRAAILTGAGS CCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC AYCVGGDLSDGWMVRDGSAPPLDPATIGKGLLLSHTLTKPLIAAVNGACLGGGCEMLQQT EEEECCCCCCCEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCEECCHHHHHHHC DIRVSDEHATFGLPEVQRGLVPGAGSMVRLKRQIPYTKAMEMILTGEPLTAFEAYHFGLV CCEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH GHVVPAGTALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVITS HHHCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHCC ADAREGLAAFKEKREARFTGR CCHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure SAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEIDHDDGIRAAILTGAGS CHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC AYCVGGDLSDGWMVRDGSAPPLDPATIGKGLLLSHTLTKPLIAAVNGACLGGGCEMLQQT EEEECCCCCCCEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCEECCHHHHHHHC DIRVSDEHATFGLPEVQRGLVPGAGSMVRLKRQIPYTKAMEMILTGEPLTAFEAYHFGLV CCEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH GHVVPAGTALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVITS HHHCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHCC ADAREGLAAFKEKREARFTGR CCHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.05 {crotonyl-CoA}} 0.008 {2-decenoyl-CoA}} [C]
Substrates: (3S)-3-hydroxyacyl-CoA
Specific reaction: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O
General reaction: addition (of H2O to carbon carbon double bondelimination (of H2O C-O bond cleavagehydration [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9387222; 9384377 [H]