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The map label for this gene is gltC [H]

Identifier: 169627780

GI number: 169627780

Start: 679928

End: 680821

Strand: Direct

Name: gltC [H]

Synonym: MAB_0678

Alternate gene names: 169627780

Gene position: 679928-680821 (Clockwise)

Preceding gene: 169627777

Following gene: 169627783

Centisome position: 13.42

GC content: 68.34

Gene sequence:

>894_bases
ATGGATGTGCGCCGCCTGCGGATTCTGCGTGAATTTGCCGACCGGGGCACCGTCGGAGAGGTGGCGGATGCGATGAGCCT
CACGCCCTCGGCGGTATCCCAGCAGCTGAAGGTGCTGACGCGTGAGGCCGGTGTACCGCTGCTGCGTCAGGATGGCCGGG
GTATCGCGCTCACCGAGGCCGGCCACGCGCTGGTGCTGCGCGCCGATGAGGTGATTGCCGCGGTCGATCGTGCGGACGAG
GAAATGGTGGCGTACCGGGAGGGCACGCAGCCTGTGGTGCGGGTGGCGTCATTCCCATCCGGAGCGGGGGTGCTGCTGCC
CAGGGTGGTGGCGGCCGTGGCGGAGGCGGTGGACATACGCCCCAGCGATGAGGACGTCACCTACGGCGAGGCGCCGGGGC
TGCTGACCGAATACGACCTTGTCATCACGCACCGCGACGAGCGGGCCGCGGCCTTGCAGTCGCCGAGAGTCTGGTCGACG
ACACTGCTGCGTGAGCCGATCGATCTGCTGGTACACCGGGATCACCCACTTGCGGCCTGCGACTCGGTGACACCGGCCGA
GCTGGCCGATGAGACGTGGATCAGCGTGCCCGAGGGCTTCCCGGTTGACGACGTTCTGGTCTCTCTCGGGGTTTCCACCG
GGATCATTCCGCGAGTCCGGTTCCGGTTCAAGGATTTTCAGATCGTTGAGGACATGGTGGCTCATGGGCACGGTGTCGCG
CTGATGCCGCGATACGCGAGCCGCAGCCCGCGGGTGGCAAGAGTGGTGATCCGCGAGGTGCGTGCCGCGCGGTTGTACGA
GGTGTTGGCGCGGCCCGGTGCACGGCACCGGCCGGCTATCGCCGCGACCATCCAGGGGCTGCGGGACGCGGCGGCGGTGC
TGGAATCGCGTTAG

Upstream 100 bases:

>100_bases
ATCCGAGGAGACGGTGCCGAGTAGTCATGGCGTCGATCCTGCGCAGCGAAACGATTCAGCACAATCTAATTAATATGCAC
TATTCATGTAGTTTTACTTC

Downstream 100 bases:

>100_bases
GCCGAGTACTCGGCGATATGCTCGAGGACCAACGCGGCAGTCTCAAGAGGCCGCTCCTCGGCGATCCAATGGGACACACC
CTCGAAGACCTCGAAGCGAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MDVRRLRILREFADRGTVGEVADAMSLTPSAVSQQLKVLTREAGVPLLRQDGRGIALTEAGHALVLRADEVIAAVDRADE
EMVAYREGTQPVVRVASFPSGAGVLLPRVVAAVAEAVDIRPSDEDVTYGEAPGLLTEYDLVITHRDERAAALQSPRVWST
TLLREPIDLLVHRDHPLAACDSVTPAELADETWISVPEGFPVDDVLVSLGVSTGIIPRVRFRFKDFQIVEDMVAHGHGVA
LMPRYASRSPRVARVVIREVRAARLYEVLARPGARHRPAIAATIQGLRDAAAVLESR

Sequences:

>Translated_297_residues
MDVRRLRILREFADRGTVGEVADAMSLTPSAVSQQLKVLTREAGVPLLRQDGRGIALTEAGHALVLRADEVIAAVDRADE
EMVAYREGTQPVVRVASFPSGAGVLLPRVVAAVAEAVDIRPSDEDVTYGEAPGLLTEYDLVITHRDERAAALQSPRVWST
TLLREPIDLLVHRDHPLAACDSVTPAELADETWISVPEGFPVDDVLVSLGVSTGIIPRVRFRFKDFQIVEDMVAHGHGVA
LMPRYASRSPRVARVVIREVRAARLYEVLARPGARHRPAIAATIQGLRDAAAVLESR
>Mature_297_residues
MDVRRLRILREFADRGTVGEVADAMSLTPSAVSQQLKVLTREAGVPLLRQDGRGIALTEAGHALVLRADEVIAAVDRADE
EMVAYREGTQPVVRVASFPSGAGVLLPRVVAAVAEAVDIRPSDEDVTYGEAPGLLTEYDLVITHRDERAAALQSPRVWST
TLLREPIDLLVHRDHPLAACDSVTPAELADETWISVPEGFPVDDVLVSLGVSTGIIPRVRFRFKDFQIVEDMVAHGHGVA
LMPRYASRSPRVARVVIREVRAARLYEVLARPGARHRPAIAATIQGLRDAAAVLESR

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=253, Percent_Identity=25.296442687747, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32331; Mature: 32331

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRRLRILREFADRGTVGEVADAMSLTPSAVSQQLKVLTREAGVPLLRQDGRGIALTEA
CCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCEEEEECC
GHALVLRADEVIAAVDRADEEMVAYREGTQPVVRVASFPSGAGVLLPRVVAAVAEAVDIR
CCEEEEEHHHHHHHHHHCCHHHHHHHCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHCCC
PSDEDVTYGEAPGLLTEYDLVITHRDERAAALQSPRVWSTTLLREPIDLLVHRDHPLAAC
CCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCHHC
DSVTPAELADETWISVPEGFPVDDVLVSLGVSTGIIPRVRFRFKDFQIVEDMVAHGHGVA
CCCCHHHHCCCCEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
LMPRYASRSPRVARVVIREVRAARLYEVLARPGARHRPAIAATIQGLRDAAAVLESR
EECHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDVRRLRILREFADRGTVGEVADAMSLTPSAVSQQLKVLTREAGVPLLRQDGRGIALTEA
CCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCEEEEECC
GHALVLRADEVIAAVDRADEEMVAYREGTQPVVRVASFPSGAGVLLPRVVAAVAEAVDIR
CCEEEEEHHHHHHHHHHCCHHHHHHHCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHCCC
PSDEDVTYGEAPGLLTEYDLVITHRDERAAALQSPRVWSTTLLREPIDLLVHRDHPLAAC
CCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCHHC
DSVTPAELADETWISVPEGFPVDDVLVSLGVSTGIIPRVRFRFKDFQIVEDMVAHGHGVA
CCCCHHHHCCCCEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
LMPRYASRSPRVARVVIREVRAARLYEVLARPGARHRPAIAATIQGLRDAAAVLESR
EECHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]