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The map label for this gene is resE [H]

Identifier: 169627777

GI number: 169627777

Start: 676921

End: 678498

Strand: Direct

Name: resE [H]

Synonym: MAB_0674

Alternate gene names: 169627777

Gene position: 676921-678498 (Clockwise)

Preceding gene: 169627776

Following gene: 169627780

Centisome position: 13.36

GC content: 66.48

Gene sequence:

>1578_bases
GTGGCGTGGGATACGTATTGCGCGAGCCGCGATGAGCGTCTGCGCGAAGAGCAGTTGGCGCTGCTAGTGGCAGTCCCCGG
CGTTCGTCGGGGTGTACCGCTGCGGGTGAGCCTTGTGGTCGGAACCCTGGTTTTGGTTGCGCTGGGGCTGGTGGCATCTG
GCATCGCGGTGACCACCACCATGCAGCGCACCATGATGAACCGCGCCGATCGTGAACTGATCGACGCCGCGAATGGATGG
GCCAATCGGCCGCCTCCACCGCCGCCGGCCTTTGAGACAACGCGCCATCGACCCCCGTCGTTGTTCTTCATCCGCACCAC
CGATGACCGTGGCCGGGTGGTCATCATGCTCAACGATCGGGCTCGGGCCGATCCCGATCTGCCCTTCGACAACGACGTGG
GTGGCCGGCCGGTCACGGTGCGGTCGTCAGACGGCGGAACCGAGTGGCGCGCGGTGTCCCGGCACGACGCGTTGGGCGGC
TACACGACTGTGGCGCGCGATATCACCGATGTGCGTACGACGGTTCGAGACCTGCTGTGGTTGCAAGTGGCGATTGGGAT
CGCGGTGCTGACCGTGCTCGGCGTAGCCGGGTATTGGTTGGTGCACCGCAGCCTGCGTCCGCTGGCTGAGGTGGAGGCGA
CGGCCGCCGACATCGCCGCCGGGCACCTGGACCGCCGGGTTCCAGAACGTGACCCGCGCACCGAAGTGGGCCGATTATCG
TTGGCGCTCAACGGAATGCTCGCGCAAATCCAGCGTGCGGTGGCAGACTCGGAGAAATCCGCGAAGGCCGCGCGCACCTC
CGAAGAGCGCATGCGCCGCTTCATCACCGATGCCAGTCATGAGCTGCGCACACCCTTGACCACCATTCGCGGCTATGCGG
AGCTCTATCGACAGGGCGCGGCCACCGATACCGAACTGGTGCTCGGCCGCATCGAAGGGGAGTCAACCCGCATGGGACAA
CTGGTGGAGGATCTGCTGCTGCTGGCGCGGTTGGACGCGCATCGCCCCATGGAGCAGCGGTTGGTCGATTTGCTGGTGCT
GGCCACCGACGCCGTTCACGACGCGAAAGCCACTGCCCCCGAACGTGATGTGGAATTGGAGGTGTTCGATGGCCCGGGCA
CTCCGGAGGTGATCGGTGATGAGCTCAGGCTACGTCAGGTCCTCGGCAATCTGGTGAGCAACGCATTGGGTCACACCACT
GCCGCAGTGCGGGTCCGGGTCGGTACCGAGGGCGATGACGCCGTCCTCGAGGTCATCGACCGTGGACCCGGTATGACCAA
GACGGACGCCGAGCGTGTCTTCGAACGGTTCTATCGCGCGGATTCCTCGCGCACCCGAAGCAGCGGCGGCACCGGACTCG
GCCTGTCGATCGTTGACGCCCTCACCGCCGCGCACGGTGGCACCGTCACGGTGCACACCGCGCCCGGCGCGGGCTGTCGA
TTCGAGGTTCGGCTGCCGCGCGCCGACATGACCGACGACGACGCGGACGTGGACGAGCCCGAATCGGCGACGCCGGATGC
CGCGGCATCCGAACCAAAGATCGTGCGGGCTAGTCGATCTGAGTCAGCGCAGCCTTGA

Upstream 100 bases:

>100_bases
CGCTACGACTTCGGTGGCGACGTGAACGTGGTGGAGTCCTACGTCTCGTATCTGCGCCGCAAGATCGACAACGGTGAGAA
GCGGCTATTGCATACTCTTC

Downstream 100 bases:

>100_bases
TCTTGGCCTGTGCCTCGTCGAGGGATTCCGCCGAAGCGTTGGGATCGGCATTCTCGAAGCTGAAATCGGTGAGCTGGTAG
CCCGGGAAAACATGTACGTG

Product: putative sensor histidine kinase PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MAWDTYCASRDERLREEQLALLVAVPGVRRGVPLRVSLVVGTLVLVALGLVASGIAVTTTMQRTMMNRADRELIDAANGW
ANRPPPPPPAFETTRHRPPSLFFIRTTDDRGRVVIMLNDRARADPDLPFDNDVGGRPVTVRSSDGGTEWRAVSRHDALGG
YTTVARDITDVRTTVRDLLWLQVAIGIAVLTVLGVAGYWLVHRSLRPLAEVEATAADIAAGHLDRRVPERDPRTEVGRLS
LALNGMLAQIQRAVADSEKSAKAARTSEERMRRFITDASHELRTPLTTIRGYAELYRQGAATDTELVLGRIEGESTRMGQ
LVEDLLLLARLDAHRPMEQRLVDLLVLATDAVHDAKATAPERDVELEVFDGPGTPEVIGDELRLRQVLGNLVSNALGHTT
AAVRVRVGTEGDDAVLEVIDRGPGMTKTDAERVFERFYRADSSRTRSSGGTGLGLSIVDALTAAHGGTVTVHTAPGAGCR
FEVRLPRADMTDDDADVDEPESATPDAAASEPKIVRASRSESAQP

Sequences:

>Translated_525_residues
MAWDTYCASRDERLREEQLALLVAVPGVRRGVPLRVSLVVGTLVLVALGLVASGIAVTTTMQRTMMNRADRELIDAANGW
ANRPPPPPPAFETTRHRPPSLFFIRTTDDRGRVVIMLNDRARADPDLPFDNDVGGRPVTVRSSDGGTEWRAVSRHDALGG
YTTVARDITDVRTTVRDLLWLQVAIGIAVLTVLGVAGYWLVHRSLRPLAEVEATAADIAAGHLDRRVPERDPRTEVGRLS
LALNGMLAQIQRAVADSEKSAKAARTSEERMRRFITDASHELRTPLTTIRGYAELYRQGAATDTELVLGRIEGESTRMGQ
LVEDLLLLARLDAHRPMEQRLVDLLVLATDAVHDAKATAPERDVELEVFDGPGTPEVIGDELRLRQVLGNLVSNALGHTT
AAVRVRVGTEGDDAVLEVIDRGPGMTKTDAERVFERFYRADSSRTRSSGGTGLGLSIVDALTAAHGGTVTVHTAPGAGCR
FEVRLPRADMTDDDADVDEPESATPDAAASEPKIVRASRSESAQP
>Mature_524_residues
AWDTYCASRDERLREEQLALLVAVPGVRRGVPLRVSLVVGTLVLVALGLVASGIAVTTTMQRTMMNRADRELIDAANGWA
NRPPPPPPAFETTRHRPPSLFFIRTTDDRGRVVIMLNDRARADPDLPFDNDVGGRPVTVRSSDGGTEWRAVSRHDALGGY
TTVARDITDVRTTVRDLLWLQVAIGIAVLTVLGVAGYWLVHRSLRPLAEVEATAADIAAGHLDRRVPERDPRTEVGRLSL
ALNGMLAQIQRAVADSEKSAKAARTSEERMRRFITDASHELRTPLTTIRGYAELYRQGAATDTELVLGRIEGESTRMGQL
VEDLLLLARLDAHRPMEQRLVDLLVLATDAVHDAKATAPERDVELEVFDGPGTPEVIGDELRLRQVLGNLVSNALGHTTA
AVRVRVGTEGDDAVLEVIDRGPGMTKTDAERVFERFYRADSSRTRSSGGTGLGLSIVDALTAAHGGTVTVHTAPGAGCRF
EVRLPRADMTDDDADVDEPESATPDAAASEPKIVRASRSESAQP

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=308, Percent_Identity=33.4415584415584, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790346, Length=283, Percent_Identity=31.095406360424, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787894, Length=309, Percent_Identity=30.42071197411, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788393, Length=289, Percent_Identity=30.4498269896194, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=32.7354260089686, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789149, Length=370, Percent_Identity=26.2162162162162, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=27.8969957081545, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789808, Length=298, Percent_Identity=29.5302013422819, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788279, Length=223, Percent_Identity=29.1479820627803, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790861, Length=324, Percent_Identity=27.1604938271605, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=30.2521008403361, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=28.0701754385965, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790436, Length=212, Percent_Identity=28.7735849056604, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=335, Percent_Identity=27.1641791044776, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790551, Length=309, Percent_Identity=27.1844660194175, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=27.0491803278689, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789403, Length=221, Percent_Identity=32.1266968325792, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=27.3504273504274, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787374, Length=310, Percent_Identity=23.8709677419355, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56958; Mature: 56827

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWDTYCASRDERLREEQLALLVAVPGVRRGVPLRVSLVVGTLVLVALGLVASGIAVTTT
CCCCCHHCCHHHHHHHHHHEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHH
MQRTMMNRADRELIDAANGWANRPPPPPPAFETTRHRPPSLFFIRTTDDRGRVVIMLNDR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCC
ARADPDLPFDNDVGGRPVTVRSSDGGTEWRAVSRHDALGGYTTVARDITDVRTTVRDLLW
CCCCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
LQVAIGIAVLTVLGVAGYWLVHRSLRPLAEVEATAADIAAGHLDRRVPERDPRTEVGRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LALNGMLAQIQRAVADSEKSAKAARTSEERMRRFITDASHELRTPLTTIRGYAELYRQGA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHCCC
ATDTELVLGRIEGESTRMGQLVEDLLLLARLDAHRPMEQRLVDLLVLATDAVHDAKATAP
CCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
ERDVELEVFDGPGTPEVIGDELRLRQVLGNLVSNALGHTTAAVRVRVGTEGDDAVLEVID
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHH
RGPGMTKTDAERVFERFYRADSSRTRSSGGTGLGLSIVDALTAAHGGTVTVHTAPGAGCR
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCE
FEVRLPRADMTDDDADVDEPESATPDAAASEPKIVRASRSESAQP
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
AWDTYCASRDERLREEQLALLVAVPGVRRGVPLRVSLVVGTLVLVALGLVASGIAVTTT
CCCCHHCCHHHHHHHHHHEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHH
MQRTMMNRADRELIDAANGWANRPPPPPPAFETTRHRPPSLFFIRTTDDRGRVVIMLNDR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCC
ARADPDLPFDNDVGGRPVTVRSSDGGTEWRAVSRHDALGGYTTVARDITDVRTTVRDLLW
CCCCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
LQVAIGIAVLTVLGVAGYWLVHRSLRPLAEVEATAADIAAGHLDRRVPERDPRTEVGRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LALNGMLAQIQRAVADSEKSAKAARTSEERMRRFITDASHELRTPLTTIRGYAELYRQGA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHCCC
ATDTELVLGRIEGESTRMGQLVEDLLLLARLDAHRPMEQRLVDLLVLATDAVHDAKATAP
CCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
ERDVELEVFDGPGTPEVIGDELRLRQVLGNLVSNALGHTTAAVRVRVGTEGDDAVLEVID
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHH
RGPGMTKTDAERVFERFYRADSSRTRSSGGTGLGLSIVDALTAAHGGTVTVHTAPGAGCR
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCE
FEVRLPRADMTDDDADVDEPESATPDAAASEPKIVRASRSESAQP
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]