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The map label for this gene is fbpC [H]

Identifier: 169627280

GI number: 169627280

Start: 171674

End: 172648

Strand: Direct

Name: fbpC [H]

Synonym: MAB_0175

Alternate gene names: 169627280

Gene position: 171674-172648 (Clockwise)

Preceding gene: 169627279

Following gene: 169627281

Centisome position: 3.39

GC content: 63.69

Gene sequence:

>975_bases
ATGAGCGTGCGCGTGAAAGCCCGCCGCGTGCTGTCGGCCCTGTTAGCGGCGTTTGTGATGCCCGTGTCGATGGCTGCGGC
CATGACGATCAACCCCGCCACCGCGCATGCCTTCTCGCGCGAGGGGCTCCCGGTCGAGTACCTGGATGTCTATTCCAATT
CGATGGGTCGCAACATTCGCGTCGAATTCCAGGGCGGCGGGCCCAAGGCCGTCTATTTGCTGGACGGGCTGCGTGCCCAG
GACGACTTCAACGGCTGGGATATCAACACCGCGGCGTTCGAATGGTTCTACCAATCGGGAATTTCGGTCGTCATGCCCGT
GGGTGGACAGTCGAGCTTCTACACCGACTGGTATTCGCCGTCGGCGCTCAACAAGCAGCCCTACACGTACAAGTGGGAAA
CATTCCTCACGCAGGAACTGCCCGCCTACCTCGCCACCAATAAGCAGATATCGGCCACCGGTAACGGCGTCGTCGGGCTG
TCGATGAGTGGCGGTGCCGCGCTGATCCTGGCCGCGTTCCACCCGGCGCAGTTCCGGTTCGCCGGTTCGCTTTCCGGCTT
CCTCAACCCGTCGACCATCTTCATGACCAACGCGATCCGGGTCGCCATGCTCGATGCGGGCAGCTACAGCGTGGACAACA
TGTGGGGGCCGCCGTGGGATCCGGCATGGCGCCGCAACGACCCCACCGTGCAGGCGCAGGCGCTGGTCGCGGCCGGCACT
CGCCTCTATATCTATTGCGCGCCAGGTGGTTCGACGCCGATCGATGACAACACCGATGCCGGTGTGGCCCTGAGCGCCAG
CAGTCTGGAGTCGCTGGCGGTGGCCGGTAACAAGGCATTCCAGCAGGCGTACACCGCCGCGGGCGGAAGGAACGCCAACT
TTGTCTTCCCCGCGTCCGGGAACCACTCCTGGCCGTATTGGGGACAGCAACTGCAGGCCCTCAAGGGTGATCTGATTGCC
ACGCTTAACGGCTAA

Upstream 100 bases:

>100_bases
GAAGACGACGTTGTCGGACACTTCAGGCGCAACGTTGCGTGACAGAAGTGCCCAGTGTGACTCCTGTGAATTCCTCTATA
TGAAACGGATGGACCCCCAG

Downstream 100 bases:

>100_bases
GATCCCGGGGCACCTTGGGAAGGTCCGCAGGCGCACGTAGTGGGAAATCGATTGAGACAGATGGGAAAACGAAGTAAATG
AAGCTCTTTTCGAAGATGCG

Product: antigen 85-C precursor

Products: NA

Alternate protein names: Antigen 85 complex C; 85C; Ag85C; Fibronectin-binding protein C; Mycolyl transferase 85C [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSVRVKARRVLSALLAAFVMPVSMAAAMTINPATAHAFSREGLPVEYLDVYSNSMGRNIRVEFQGGGPKAVYLLDGLRAQ
DDFNGWDINTAAFEWFYQSGISVVMPVGGQSSFYTDWYSPSALNKQPYTYKWETFLTQELPAYLATNKQISATGNGVVGL
SMSGGAALILAAFHPAQFRFAGSLSGFLNPSTIFMTNAIRVAMLDAGSYSVDNMWGPPWDPAWRRNDPTVQAQALVAAGT
RLYIYCAPGGSTPIDDNTDAGVALSASSLESLAVAGNKAFQQAYTAAGGRNANFVFPASGNHSWPYWGQQLQALKGDLIA
TLNG

Sequences:

>Translated_324_residues
MSVRVKARRVLSALLAAFVMPVSMAAAMTINPATAHAFSREGLPVEYLDVYSNSMGRNIRVEFQGGGPKAVYLLDGLRAQ
DDFNGWDINTAAFEWFYQSGISVVMPVGGQSSFYTDWYSPSALNKQPYTYKWETFLTQELPAYLATNKQISATGNGVVGL
SMSGGAALILAAFHPAQFRFAGSLSGFLNPSTIFMTNAIRVAMLDAGSYSVDNMWGPPWDPAWRRNDPTVQAQALVAAGT
RLYIYCAPGGSTPIDDNTDAGVALSASSLESLAVAGNKAFQQAYTAAGGRNANFVFPASGNHSWPYWGQQLQALKGDLIA
TLNG
>Mature_323_residues
SVRVKARRVLSALLAAFVMPVSMAAAMTINPATAHAFSREGLPVEYLDVYSNSMGRNIRVEFQGGGPKAVYLLDGLRAQD
DFNGWDINTAAFEWFYQSGISVVMPVGGQSSFYTDWYSPSALNKQPYTYKWETFLTQELPAYLATNKQISATGNGVVGLS
MSGGAALILAAFHPAQFRFAGSLSGFLNPSTIFMTNAIRVAMLDAGSYSVDNMWGPPWDPAWRRNDPTVQAQALVAAGTR
LYIYCAPGGSTPIDDNTDAGVALSASSLESLAVAGNKAFQQAYTAAGGRNANFVFPASGNHSWPYWGQQLQALKGDLIAT
LNG

Specific function: Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintain

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial A85 antigen family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 34759; Mature: 34628

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRVKARRVLSALLAAFVMPVSMAAAMTINPATAHAFSREGLPVEYLDVYSNSMGRNIR
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHCCCCCCCHHHHHHHCCCCCEEE
VEFQGGGPKAVYLLDGLRAQDDFNGWDINTAAFEWFYQSGISVVMPVGGQSSFYTDWYSP
EEEECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEECCCCC
SALNKQPYTYKWETFLTQELPAYLATNKQISATGNGVVGLSMSGGAALILAAFHPAQFRF
CCCCCCCCEEEHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCEEEEEEEECCCCEEE
AGSLSGFLNPSTIFMTNAIRVAMLDAGSYSVDNMWGPPWDPAWRRNDPTVQAQALVAAGT
ECCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
RLYIYCAPGGSTPIDDNTDAGVALSASSLESLAVAGNKAFQQAYTAAGGRNANFVFPASG
EEEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCC
NHSWPYWGQQLQALKGDLIATLNG
CCCCCHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure 
SVRVKARRVLSALLAAFVMPVSMAAAMTINPATAHAFSREGLPVEYLDVYSNSMGRNIR
CCCHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHCCCCCCCHHHHHHHCCCCCEEE
VEFQGGGPKAVYLLDGLRAQDDFNGWDINTAAFEWFYQSGISVVMPVGGQSSFYTDWYSP
EEEECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEECCCCC
SALNKQPYTYKWETFLTQELPAYLATNKQISATGNGVVGLSMSGGAALILAAFHPAQFRF
CCCCCCCCEEEHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCEEEEEEEECCCCEEE
AGSLSGFLNPSTIFMTNAIRVAMLDAGSYSVDNMWGPPWDPAWRRNDPTVQAQALVAAGT
ECCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
RLYIYCAPGGSTPIDDNTDAGVALSASSLESLAVAGNKAFQQAYTAAGGRNANFVFPASG
EEEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCC
NHSWPYWGQQLQALKGDLIATLNG
CCCCCHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]