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The map label for this gene is kdgR [H]

Identifier: 169627182

GI number: 169627182

Start: 74058

End: 74909

Strand: Direct

Name: kdgR [H]

Synonym: MAB_0077

Alternate gene names: 169627182

Gene position: 74058-74909 (Clockwise)

Preceding gene: 169627181

Following gene: 169627183

Centisome position: 1.46

GC content: 68.54

Gene sequence:

>852_bases
ATGACCATCACCGCCGATTCGGCCACCCCCAGCGCCGTCATCGATCGGGTATCGCTGCTGCTTGACGCCTTTGATGGCCC
CGGTCGGCTCACGCTGGCGCAGTTGGTGCGCCGGACCGGACTCCCCCGCTCGTCTGTGCACCGGATGCTGGAACGGCTGG
TGCAGCTGCGCTGGTTACGGCGTGACGGCCGTGACTATGAGCTGGGCACGCGGCTGGTGGAGCTTGGCTCGCTGGCAGTG
CACCAGGACAGGTTGCACGCCGCGGCGCTGCCGATGCTGCACGAGCTGCATCGCGCCACCGGGCTCGTCGTGCATCTGTC
CATCCTGGACGGCGCCGACGTCGTCTATCTGGAGAAGATCGGCGCCGGGATCGGTGCCGCCGTGGCCACTCGCATCGGTG
GCCGCCAGCCGGCGCACTGTACGGCCTCCGGCAAGGCAATCCTGGCGTATCGTGCCCAGATCCTGGACGGCTGCACCGCG
CTGGCCCGTAAGACCCGCTACTCGATCGGTTCGGCGGCCCAGTTGCGGCCGGAGTTGGACAAGGTGCGTGGGCATGGTGT
GGCCTTCGACCGTGAGGAGCTGCAGCAGGGCATCGGCTGCGTGGCGGCTCCGATCGGAAGCATCGGCGATGCCGTGGCCG
CCGTGTCGGTGTGTGGCCCGATGACGCGGATGACCTTCGACCAGCGCCTGGCGGCCCCGGTGCGGATGACGGCGATGGGA
ATCTGGCGCAATGTGGAGAACGGTCCGAGCCGAGTGGCCCCGACCTTGCAGCCGATTCGCCCACTGCGTTGCGGTCCCGC
CGCCTCCTCAACTGGACGCGAGATGAACTCGCCCGCATTGCAGTACGCGTGA

Upstream 100 bases:

>100_bases
CGTTTATCGGGAGTTGTGTCGGAGGACACACCCATGATACAAACAGCTATATGACTAATAGTCATATGTGACCGAGACCC
CAACGCCGTGGGAGGGCACC

Downstream 100 bases:

>100_bases
CCCTCGATCCTCAGCTGGCCGCCCTGCTACCGGCGCTCAATGCGGGCTTTCCGCGCGTCGAGAAGATGACGGGTGCACAG
GCGCGGGCCGCAATCCGTGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTITADSATPSAVIDRVSLLLDAFDGPGRLTLAQLVRRTGLPRSSVHRMLERLVQLRWLRRDGRDYELGTRLVELGSLAV
HQDRLHAAALPMLHELHRATGLVVHLSILDGADVVYLEKIGAGIGAAVATRIGGRQPAHCTASGKAILAYRAQILDGCTA
LARKTRYSIGSAAQLRPELDKVRGHGVAFDREELQQGIGCVAAPIGSIGDAVAAVSVCGPMTRMTFDQRLAAPVRMTAMG
IWRNVENGPSRVAPTLQPIRPLRCGPAASSTGREMNSPALQYA

Sequences:

>Translated_283_residues
MTITADSATPSAVIDRVSLLLDAFDGPGRLTLAQLVRRTGLPRSSVHRMLERLVQLRWLRRDGRDYELGTRLVELGSLAV
HQDRLHAAALPMLHELHRATGLVVHLSILDGADVVYLEKIGAGIGAAVATRIGGRQPAHCTASGKAILAYRAQILDGCTA
LARKTRYSIGSAAQLRPELDKVRGHGVAFDREELQQGIGCVAAPIGSIGDAVAAVSVCGPMTRMTFDQRLAAPVRMTAMG
IWRNVENGPSRVAPTLQPIRPLRCGPAASSTGREMNSPALQYA
>Mature_282_residues
TITADSATPSAVIDRVSLLLDAFDGPGRLTLAQLVRRTGLPRSSVHRMLERLVQLRWLRRDGRDYELGTRLVELGSLAVH
QDRLHAAALPMLHELHRATGLVVHLSILDGADVVYLEKIGAGIGAAVATRIGGRQPAHCTASGKAILAYRAQILDGCTAL
ARKTRYSIGSAAQLRPELDKVRGHGVAFDREELQQGIGCVAAPIGSIGDAVAAVSVCGPMTRMTFDQRLAAPVRMTAMGI
WRNVENGPSRVAPTLQPIRPLRCGPAASSTGREMNSPALQYA

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=225, Percent_Identity=32.8888888888889, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786468, Length=226, Percent_Identity=32.3008849557522, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082359, Length=214, Percent_Identity=28.5046728971963, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788581, Length=209, Percent_Identity=29.6650717703349, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790752, Length=200, Percent_Identity=29, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789999, Length=230, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1786715, Length=197, Percent_Identity=26.9035532994924, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30273; Mature: 30141

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITADSATPSAVIDRVSLLLDAFDGPGRLTLAQLVRRTGLPRSSVHRMLERLVQLRWLR
CEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RDGRDYELGTRLVELGSLAVHQDRLHAAALPMLHELHRATGLVVHLSILDGADVVYLEKI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEHHHH
GAGIGAAVATRIGGRQPAHCTASGKAILAYRAQILDGCTALARKTRYSIGSAAQLRPELD
CCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHH
KVRGHGVAFDREELQQGIGCVAAPIGSIGDAVAAVSVCGPMTRMTFDQRLAAPVRMTAMG
HHCCCCCEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHH
IWRNVENGPSRVAPTLQPIRPLRCGPAASSTGREMNSPALQYA
HHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TITADSATPSAVIDRVSLLLDAFDGPGRLTLAQLVRRTGLPRSSVHRMLERLVQLRWLR
EEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RDGRDYELGTRLVELGSLAVHQDRLHAAALPMLHELHRATGLVVHLSILDGADVVYLEKI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEHHHH
GAGIGAAVATRIGGRQPAHCTASGKAILAYRAQILDGCTALARKTRYSIGSAAQLRPELD
CCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHH
KVRGHGVAFDREELQQGIGCVAAPIGSIGDAVAAVSVCGPMTRMTFDQRLAAPVRMTAMG
HHCCCCCEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHH
IWRNVENGPSRVAPTLQPIRPLRCGPAASSTGREMNSPALQYA
HHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]