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The map label for this gene is hsaC [H]

Identifier: 169627181

GI number: 169627181

Start: 72983

End: 73882

Strand: Direct

Name: hsaC [H]

Synonym: MAB_0076

Alternate gene names: 169627181

Gene position: 72983-73882 (Clockwise)

Preceding gene: 169627180

Following gene: 169627182

Centisome position: 1.44

GC content: 66.89

Gene sequence:

>900_bases
ATGTTGACGAGCTTGGGATACCTGACCGTTGCGACCCGGGACATGGACCGCTGGAGACATTTCGCGCTGCGTGTGCTGGG
TTTCGCCGAAGGCAGCGGGCCCGATCCCGACGCCCTGTATCTGCGGATGGACGAGCGTGCCGCGCGCGTCGTGGTGGTGC
CGGGCGAGACGGATCAGGTCATCACCGTGGGCTGGGAGGTGCGAGACGGCGCGGCGTTGCGTGCGGTCGTGCGGGCCTTG
GAGGCAGCCGACATCGGCGTCGAGCGGTTGTCGCCGGAGGAGGCCGACAGCCGCCGGGCCGAGGAGGTGGTGGCTTTCAC
CGACCCCGCTGGTACCCCCGTGGAGGTGTTCCACGGACCGGTGCTGGACCATAGCCCGGTGGTGACGCCGTACGGGGCGC
GATTCGTGACGGGTGCCCAGGGGCTCGGACACGTGGTGCTGCCGGTCACCGACCCGGAGGGCGCCTTCACCTTCTATACC
GAGGTGCTCGGGTTCCGGCCGCGGGGCGCCTTTCGGATTCCCGCGCCGCCGGAATTCGGTCCTATGCGGGTGCGCTTCCT
GGGCATCAACGAACGTCATCACAGTCTCGCGCTGTGCCCCGCGCCGCATGGTGGCGCACCCGGGCTGGTGCATGTGATGG
TGGAGGTGGACAGCCTCGATGCCGTCGGGCAGGCGCTCGACCGCGTGCTCAAGGACGATTACTCGTTGTCGTCCACACTG
GGCCGGCACACCAACGACAAGATGGTGTCCTTTTATGTACGGGCACCAGGCGGATGGGATATCGAGTTCGGGACCGACGG
CATGCGCGTCGACGAAACGTGTTACACCGCAGAAGAAATCACCGCAGACAGTTATTGGGGACACGACTGGTCCGGTAGCC
AGCCGCTGGCCGCGATGTAA

Upstream 100 bases:

>100_bases
GTTTGGCACACGCGATTCACGTGCCCAGCACGGTGTTCCACGCGTCGGCACTGAGCTCGTTGGGTATCGAGCCGCAGGGC
CCGCTGAGGTCGATGATCTG

Downstream 100 bases:

>100_bases
TCCTCCCCCCCGTTCGGCCGAGCAGACGCTTGGTGCACGCGAAGTCCAGGCGCGTGTGCACCAGGCGTCTGTTCGCGTTT
ATCGGGAGTTGTGTCGGAGG

Product: putative 2,3-dihydroxybiphenyl 1,2-dioxygenase or glyoxalase/bleomycin resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MLTSLGYLTVATRDMDRWRHFALRVLGFAEGSGPDPDALYLRMDERAARVVVVPGETDQVITVGWEVRDGAALRAVVRAL
EAADIGVERLSPEEADSRRAEEVVAFTDPAGTPVEVFHGPVLDHSPVVTPYGARFVTGAQGLGHVVLPVTDPEGAFTFYT
EVLGFRPRGAFRIPAPPEFGPMRVRFLGINERHHSLALCPAPHGGAPGLVHVMVEVDSLDAVGQALDRVLKDDYSLSSTL
GRHTNDKMVSFYVRAPGGWDIEFGTDGMRVDETCYTAEEITADSYWGHDWSGSQPLAAM

Sequences:

>Translated_299_residues
MLTSLGYLTVATRDMDRWRHFALRVLGFAEGSGPDPDALYLRMDERAARVVVVPGETDQVITVGWEVRDGAALRAVVRAL
EAADIGVERLSPEEADSRRAEEVVAFTDPAGTPVEVFHGPVLDHSPVVTPYGARFVTGAQGLGHVVLPVTDPEGAFTFYT
EVLGFRPRGAFRIPAPPEFGPMRVRFLGINERHHSLALCPAPHGGAPGLVHVMVEVDSLDAVGQALDRVLKDDYSLSSTL
GRHTNDKMVSFYVRAPGGWDIEFGTDGMRVDETCYTAEEITADSYWGHDWSGSQPLAAM
>Mature_299_residues
MLTSLGYLTVATRDMDRWRHFALRVLGFAEGSGPDPDALYLRMDERAARVVVVPGETDQVITVGWEVRDGAALRAVVRAL
EAADIGVERLSPEEADSRRAEEVVAFTDPAGTPVEVFHGPVLDHSPVVTPYGARFVTGAQGLGHVVLPVTDPEGAFTFYT
EVLGFRPRGAFRIPAPPEFGPMRVRFLGINERHHSLALCPAPHGGAPGLVHVMVEVDSLDAVGQALDRVLKDDYSLSSTL
GRHTNDKMVSFYVRAPGGWDIEFGTDGMRVDETCYTAEEITADSYWGHDWSGSQPLAAM

Specific function: Catalyzes the meta-cleavage of 3,4-dihydroxy-9,10- seconandrost-1,3,5(10)-triene-9,17-dione (3,4-DHSA) to produce 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4- oic acid (4,9-DSHA). Also involved in biphenyl and polychlorinated biphenyls

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR000486 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 32529; Mature: 32529

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00082 EXTRADIOL_DIOXYGENAS ; PS00934 GLYOXALASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSLGYLTVATRDMDRWRHFALRVLGFAEGSGPDPDALYLRMDERAARVVVVPGETDQV
CCCCCEEEEEEECCHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCE
ITVGWEVRDGAALRAVVRALEAADIGVERLSPEEADSRRAEEVVAFTDPAGTPVEVFHGP
EEEEEEECCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHEEEEEECCCCCCHHEEECC
VLDHSPVVTPYGARFVTGAQGLGHVVLPVTDPEGAFTFYTEVLGFRPRGAFRIPAPPEFG
CCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCEECCCCCCCC
PMRVRFLGINERHHSLALCPAPHGGAPGLVHVMVEVDSLDAVGQALDRVLKDDYSLSSTL
CEEEEEEEECCCCCEEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCHHHHH
GRHTNDKMVSFYVRAPGGWDIEFGTDGMRVDETCYTAEEITADSYWGHDWSGSQPLAAM
CCCCCCCEEEEEEECCCCEEEEECCCCCEECHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTSLGYLTVATRDMDRWRHFALRVLGFAEGSGPDPDALYLRMDERAARVVVVPGETDQV
CCCCCEEEEEEECCHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCE
ITVGWEVRDGAALRAVVRALEAADIGVERLSPEEADSRRAEEVVAFTDPAGTPVEVFHGP
EEEEEEECCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHEEEEEECCCCCCHHEEECC
VLDHSPVVTPYGARFVTGAQGLGHVVLPVTDPEGAFTFYTEVLGFRPRGAFRIPAPPEFG
CCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCEECCCCCCCC
PMRVRFLGINERHHSLALCPAPHGGAPGLVHVMVEVDSLDAVGQALDRVLKDDYSLSSTL
CEEEEEEEECCCCCEEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCHHHHH
GRHTNDKMVSFYVRAPGGWDIEFGTDGMRVDETCYTAEEITADSYWGHDWSGSQPLAAM
CCCCCCCEEEEEEECCCCEEEEECCCCCEECHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA