| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is limC [H]
Identifier: 169627178
GI number: 169627178
Start: 69266
End: 70060
Strand: Reverse
Name: limC [H]
Synonym: MAB_0073c
Alternate gene names: 169627178
Gene position: 70060-69266 (Counterclockwise)
Preceding gene: 169627179
Following gene: 169627177
Centisome position: 1.38
GC content: 67.42
Gene sequence:
>795_bases ATGACCCGCCTTGGCGGCCGGGTTGCCGTCGTCACCGGCGCCGGAAAGGGCATGGGACGCACGCATTGTGAGCGTCTGGC TGAGGAGGGCTCCGACGTCATCGCCATCGACCTACCCGGATCCGACGATCTGGCGCAGACCGCCGCTGCCGTCGAGGAGC ATGGCCGGCGCTGTGTCTGGGCATTCGCCGATGTCCGTGACGCCGCGGCACTGACCGAGGCCATCGACACCGGGGTGCGG ATGCTCGGCCGGCTGGACATCGTGGTCGCCAATGCCGGGGTCTACGACGGCCTGGCTCCGTCATGCGAGCTAACCGAAGA CTCCTGGCGGCGCGCGCTGGACGTGAACCTCACCGGAGCCTGGCACACGGTCAAGGCGGGTGCCGCCCACCTTCTGGACG GCGGCTCGGTGATCATCATCAGCTCCACCAATGGGCTCAAGGGCACCGCCAACACCGCGCACTACACCGCAAGCAAGCAT GCCGTGGTGGGTTTGGCCCGCACTGCGGCCAATGAACTGGGGCCGCAGGGTATTCGGGTGAACACCGTGCATCCCGGCGC GGTGAGTACCGGAATGATCCTCAACCCGGCGGTCATCGCACGGCTGCGCCCCGATCTGGAGCACCCAACTGTCGAGGATG CCGCCGAGGCGCTGGCGGCCCGCACCCTGTTACCGGTGCCGTGGGTAGAAGCCGTCGACATCAGCAATGCGGTGGTCTTC CTGGCCTCCGACGAAGCGCGGTACATCACCGGCACCCAGCTGGTGGTCGACGCCGGACTGACACAGAAGGCATAA
Upstream 100 bases:
>100_bases TTTTCATGCCGTTCATCGGCGGTTTCGGCGTGTACGGCGCTATCTGTGCCGATGTCGCGGCCAGCGGGTACAAGGGGTTC ACCCTGGCCGGGAGCCGCGC
Downstream 100 bases:
>100_bases CGTGACGGGACGATTGACGGGCAAGGTGGCCCTGGTGACCGGCGCCGCCCGGGGCATCGGGCGCGCCCAGGCGGTGCGTT TCGCGCAGGAGGGCGCCGAC
Product: putative short chain dehydrogenase/reductase
Products: NA
Alternate protein names: (4R,6S)-carveol dehydrogenase; CDH; Carveol dehydrogenase [H]
Number of amino acids: Translated: 264; Mature: 263
Protein sequence:
>264_residues MTRLGGRVAVVTGAGKGMGRTHCERLAEEGSDVIAIDLPGSDDLAQTAAAVEEHGRRCVWAFADVRDAAALTEAIDTGVR MLGRLDIVVANAGVYDGLAPSCELTEDSWRRALDVNLTGAWHTVKAGAAHLLDGGSVIIISSTNGLKGTANTAHYTASKH AVVGLARTAANELGPQGIRVNTVHPGAVSTGMILNPAVIARLRPDLEHPTVEDAAEALAARTLLPVPWVEAVDISNAVVF LASDEARYITGTQLVVDAGLTQKA
Sequences:
>Translated_264_residues MTRLGGRVAVVTGAGKGMGRTHCERLAEEGSDVIAIDLPGSDDLAQTAAAVEEHGRRCVWAFADVRDAAALTEAIDTGVR MLGRLDIVVANAGVYDGLAPSCELTEDSWRRALDVNLTGAWHTVKAGAAHLLDGGSVIIISSTNGLKGTANTAHYTASKH AVVGLARTAANELGPQGIRVNTVHPGAVSTGMILNPAVIARLRPDLEHPTVEDAAEALAARTLLPVPWVEAVDISNAVVF LASDEARYITGTQLVVDAGLTQKA >Mature_263_residues TRLGGRVAVVTGAGKGMGRTHCERLAEEGSDVIAIDLPGSDDLAQTAAAVEEHGRRCVWAFADVRDAAALTEAIDTGVRM LGRLDIVVANAGVYDGLAPSCELTEDSWRRALDVNLTGAWHTVKAGAAHLLDGGSVIIISSTNGLKGTANTAHYTASKHA VVGLARTAANELGPQGIRVNTVHPGAVSTGMILNPAVIARLRPDLEHPTVEDAAEALAARTLLPVPWVEAVDISNAVVFL ASDEARYITGTQLVVDAGLTQKA
Specific function: Catalyzes the oxidation of carveol to carvone, with a strong stereoselectivity since it efficiently converts only the (6S)-stereoisomers, of which (-)-(4R,6S)-trans-carveol is the better substrate. Displays a broad substrate specificity with a preference
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=264, Percent_Identity=31.0606060606061, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI15277342, Length=280, Percent_Identity=33.9285714285714, Blast_Score=101, Evalue=9e-22, Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=28.7937743190661, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI4758504, Length=202, Percent_Identity=32.1782178217822, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=33, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI40254992, Length=268, Percent_Identity=32.089552238806, Blast_Score=92, Evalue=7e-19, Organism=Homo sapiens, GI4504505, Length=218, Percent_Identity=31.1926605504587, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI7705925, Length=263, Percent_Identity=30.0380228136882, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI66933014, Length=263, Percent_Identity=31.1787072243346, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=32.967032967033, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI83715985, Length=187, Percent_Identity=31.0160427807487, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=30.6878306878307, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI59889578, Length=211, Percent_Identity=31.2796208530806, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI40807363, Length=238, Percent_Identity=28.1512605042017, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI19923817, Length=267, Percent_Identity=26.2172284644195, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=26.7441860465116, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI126723750, Length=267, Percent_Identity=26.9662921348315, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI302344755, Length=108, Percent_Identity=36.1111111111111, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI210032110, Length=210, Percent_Identity=27.6190476190476, Blast_Score=69, Evalue=5e-12, Organism=Escherichia coli, GI87082100, Length=264, Percent_Identity=32.5757575757576, Blast_Score=127, Evalue=7e-31, Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=31.6602316602317, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=31.6602316602317, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=28.6259541984733, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI2367365, Length=261, Percent_Identity=30.6513409961686, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=26.9076305220884, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1787905, Length=264, Percent_Identity=28.7878787878788, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787526, Length=197, Percent_Identity=32.48730964467, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1789057, Length=263, Percent_Identity=29.277566539924, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=27.5862068965517, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1790717, Length=266, Percent_Identity=27.0676691729323, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1788891, Length=243, Percent_Identity=27.9835390946502, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI2367175, Length=258, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=2e-12, Organism=Caenorhabditis elegans, GI25147288, Length=265, Percent_Identity=30.5660377358491, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17555706, Length=263, Percent_Identity=30.7984790874525, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17568967, Length=218, Percent_Identity=31.1926605504587, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=28.4090909090909, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=30, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17531453, Length=274, Percent_Identity=28.1021897810219, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17559104, Length=274, Percent_Identity=31.7518248175182, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=26.5917602996255, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17560676, Length=268, Percent_Identity=25.7462686567164, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17544670, Length=275, Percent_Identity=25.0909090909091, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=28.3088235294118, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=31.3953488372093, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI193204405, Length=276, Percent_Identity=27.1739130434783, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17563726, Length=274, Percent_Identity=27.3722627737226, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=27.037037037037, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562908, Length=277, Percent_Identity=27.0758122743682, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=26.3940520446097, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=26.9662921348315, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI71994604, Length=264, Percent_Identity=28.030303030303, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17538182, Length=227, Percent_Identity=30.8370044052863, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=26.2886597938144, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562910, Length=275, Percent_Identity=26.1818181818182, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=26.3940520446097, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI71994600, Length=264, Percent_Identity=24.6212121212121, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560220, Length=273, Percent_Identity=26.3736263736264, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=26.7657992565056, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI193203117, Length=246, Percent_Identity=23.5772357723577, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI193203115, Length=241, Percent_Identity=24.0663900414938, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=25.6281407035176, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17564282, Length=234, Percent_Identity=27.3504273504274, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538486, Length=271, Percent_Identity=26.5682656826568, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=25.1256281407035, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=265, Percent_Identity=28.3018867924528, Blast_Score=90, Evalue=4e-19, Organism=Saccharomyces cerevisiae, GI6322861, Length=217, Percent_Identity=29.9539170506912, Blast_Score=88, Evalue=1e-18, Organism=Saccharomyces cerevisiae, GI6322226, Length=191, Percent_Identity=26.7015706806283, Blast_Score=72, Evalue=1e-13, Organism=Drosophila melanogaster, GI18859837, Length=218, Percent_Identity=34.4036697247706, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI21355319, Length=271, Percent_Identity=27.6752767527675, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI24639444, Length=264, Percent_Identity=29.9242424242424, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI17737361, Length=200, Percent_Identity=31.5, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=29.8850574712644, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24643142, Length=262, Percent_Identity=28.6259541984733, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=26.6409266409266, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI21357041, Length=265, Percent_Identity=29.0566037735849, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI281364892, Length=205, Percent_Identity=31.219512195122, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=27.4809160305344, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24640492, Length=199, Percent_Identity=26.6331658291457, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI24644337, Length=186, Percent_Identity=31.7204301075269, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24581726, Length=230, Percent_Identity=23.9130434782609, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24641388, Length=238, Percent_Identity=29.8319327731092, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 27421; Mature: 27290
Theoretical pI: Translated: 5.31; Mature: 5.31
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTRLGGRVAVVTGAGKGMGRTHCERLAEEGSDVIAIDLPGSDDLAQTAAAVEEHGRRCVW CCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEE AFADVRDAAALTEAIDTGVRMLGRLDIVVANAGVYDGLAPSCELTEDSWRRALDVNLTGA EEHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHEEEEEEECCC WHTVKAGAAHLLDGGSVIIISSTNGLKGTANTAHYTASKHAVVGLARTAANELGPQGIRV EEEHHCCCCEEECCCCEEEEECCCCCCCCCCCCEEECCCHHEEHHHHHHHHHCCCCCEEE NTVHPGAVSTGMILNPAVIARLRPDLEHPTVEDAAEALAARTLLPVPWVEAVDISNAVVF EEECCCCCCCCEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEE LASDEARYITGTQLVVDAGLTQKA EECCCCEEEECCEEEEECCCCCCC >Mature Secondary Structure TRLGGRVAVVTGAGKGMGRTHCERLAEEGSDVIAIDLPGSDDLAQTAAAVEEHGRRCVW CCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEE AFADVRDAAALTEAIDTGVRMLGRLDIVVANAGVYDGLAPSCELTEDSWRRALDVNLTGA EEHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHEEEEEEECCC WHTVKAGAAHLLDGGSVIIISSTNGLKGTANTAHYTASKHAVVGLARTAANELGPQGIRV EEEHHCCCCEEECCCCEEEEECCCCCCCCCCCCEEECCCHHEEHHHHHHHHHCCCCCEEE NTVHPGAVSTGMILNPAVIARLRPDLEHPTVEDAAEALAARTLLPVPWVEAVDISNAVVF EEECCCCCCCCEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEE LASDEARYITGTQLVVDAGLTQKA EECCCCEEEECCEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10473585 [H]