Click here to switch to the map view.

The map label for this gene is pamO [H]

Identifier: 169627179

GI number: 169627179

Start: 70057

End: 71670

Strand: Reverse

Name: pamO [H]

Synonym: MAB_0074c

Alternate gene names: 169627179

Gene position: 71670-70057 (Counterclockwise)

Preceding gene: 169627184

Following gene: 169627178

Centisome position: 1.41

GC content: 63.38

Gene sequence:

>1614_bases
GTGAAAGCCCTCGTGAAGAACGTCGATGTGGTGGTGGTCGGCGCCGGTTTCGCCGGGTTGTATGCCCTGCAGCGGCTGCG
ATCGCAGGGGTTGTCGGTCGTCGTGTTCGAAGCAGGCTCGGATGTAGGCGGCACGTGGTTCTTCAACCGCTACCCAGGCG
CCCGTTGCGATGTGGAGAGCATCGACTACTCCTATTCGTTCTCCGACGAGCTGCAACAGGAGTGGGACTGGACCGAAAAG
TACGCCGGCCAAAAAGAAATTCTGCGCTACATCAACCATGTCGCCGACCGCTTCGACCTGCGCCGTGATATCCGCTGCGG
CACCCGGGTCACCTCGGCCGTCTTCGACGAAGATCAGCTGCGCTGGACGGTGCGCACCGATCGGAACGACACGGTGAGCG
CCCGATTCTGTGTGATGGCCACCGGCGCACTGTCCACCGCCAACATGCCCACCATTCCCGGCCGGGACGCGTTCACCGGC
GAGCTGTATCACACCGGACACTGGCCCGCGTCCGGCGTGGACTTCGCCGGTAAACGGGTCGGGGTGATCGGAACCGGGTC
TTCCGGCATCCAACTGGTGCCGATCGCCGCGCAGACGGCCAAGGAACTCTTCGTCTTCCAGCGCACTGCCAATTACACTG
TGCCCGCTGGCAATACCGTGATCAGCCCCGAGCGTCGCGCCGAGGTGAAGGCCAACTACGCCGAGCGGCGTCGTCAATCA
CGGGAGAGCGGCGGTGGCTCACCGCATCAGGCCTATCCCAAGAAGACGCTCGAGATCTCGGCCGCCGAACGTCGTGCGGC
GTTCGAGAGACGCTGGGAACTCGGCGGCGTGCTGTTCGGAAAGACCTTCCCGGATCAGACGACCGACATGCGCGCCAACA
ACGAGGCCCGAGCCTTCTTCGAGGAGAAGGTCCGTGCCGTCATCCATGACCCCGCCATCGCCGACATCCTGGTCCCCACC
GATCACCCCATCGGAACCAAACGGATTTGCACGGACACCAACTACTTTCAGACCTTTAACCGCGACAACGTCCATGTGGT
GGATTTACGGGCCGCGCCCATCGAGTCCATCAATAGGCGCGGCATGACCACCACCACAAAGTATTACGAACTCGATATGA
TCGTGTTCGCCACCGGATTTGACGCGATGACCGGATCGCTGAACCGGATCGATATCCGGGGCCGCGCCGGGCGGCCGCTC
AAGGACGCCTGGCAGGCGGGCCCCCGCACCTACTTGGGACTCGGCGTGGACGGGTTCCCCAATCTGTTTGTCGTCACCGG
CCCGGGCAGTCCCTCGGTGCTCGCCAACATGGTGCTGGGCGCCGAACAACATGTCGATTGGATCGGCGACCTGCTCGACT
ACATGGCAGCCCACGGCTATTCGACGGTGGAGGCGGAGCCTCAGGCCGTTGCCGACTGGGTAACCGAATGCAATGAGCGA
GCGGCCGCCACCATGTTCCCCCAAGCCAACTCGTGGTACCTCGGGGCGAATATCCCTGGTAAGCCAAGGGTTTTCATGCC
GTTCATCGGCGGTTTCGGCGTGTACGGCGCTATCTGTGCCGATGTCGCGGCCAGCGGGTACAAGGGGTTCACCCTGGCCG
GGAGCCGCGCATGA

Upstream 100 bases:

>100_bases
TCCATGGCCTTTTCCCGATCAGCGGTCGGTTGGATCCGATTGACCGGTCACCGGGAACGACTGCCCGCCGAGAACCGATG
TCGCCCTAGCGTGACCAATC

Downstream 100 bases:

>100_bases
CCCGCCTTGGCGGCCGGGTTGCCGTCGTCACCGGCGCCGGAAAGGGCATGGGACGCACGCATTGTGAGCGTCTGGCTGAG
GAGGGCTCCGACGTCATCGC

Product: putative (cyclohexanone) monooxygenase

Products: NA

Alternate protein names: PAMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MKALVKNVDVVVVGAGFAGLYALQRLRSQGLSVVVFEAGSDVGGTWFFNRYPGARCDVESIDYSYSFSDELQQEWDWTEK
YAGQKEILRYINHVADRFDLRRDIRCGTRVTSAVFDEDQLRWTVRTDRNDTVSARFCVMATGALSTANMPTIPGRDAFTG
ELYHTGHWPASGVDFAGKRVGVIGTGSSGIQLVPIAAQTAKELFVFQRTANYTVPAGNTVISPERRAEVKANYAERRRQS
RESGGGSPHQAYPKKTLEISAAERRAAFERRWELGGVLFGKTFPDQTTDMRANNEARAFFEEKVRAVIHDPAIADILVPT
DHPIGTKRICTDTNYFQTFNRDNVHVVDLRAAPIESINRRGMTTTTKYYELDMIVFATGFDAMTGSLNRIDIRGRAGRPL
KDAWQAGPRTYLGLGVDGFPNLFVVTGPGSPSVLANMVLGAEQHVDWIGDLLDYMAAHGYSTVEAEPQAVADWVTECNER
AAATMFPQANSWYLGANIPGKPRVFMPFIGGFGVYGAICADVAASGYKGFTLAGSRA

Sequences:

>Translated_537_residues
MKALVKNVDVVVVGAGFAGLYALQRLRSQGLSVVVFEAGSDVGGTWFFNRYPGARCDVESIDYSYSFSDELQQEWDWTEK
YAGQKEILRYINHVADRFDLRRDIRCGTRVTSAVFDEDQLRWTVRTDRNDTVSARFCVMATGALSTANMPTIPGRDAFTG
ELYHTGHWPASGVDFAGKRVGVIGTGSSGIQLVPIAAQTAKELFVFQRTANYTVPAGNTVISPERRAEVKANYAERRRQS
RESGGGSPHQAYPKKTLEISAAERRAAFERRWELGGVLFGKTFPDQTTDMRANNEARAFFEEKVRAVIHDPAIADILVPT
DHPIGTKRICTDTNYFQTFNRDNVHVVDLRAAPIESINRRGMTTTTKYYELDMIVFATGFDAMTGSLNRIDIRGRAGRPL
KDAWQAGPRTYLGLGVDGFPNLFVVTGPGSPSVLANMVLGAEQHVDWIGDLLDYMAAHGYSTVEAEPQAVADWVTECNER
AAATMFPQANSWYLGANIPGKPRVFMPFIGGFGVYGAICADVAASGYKGFTLAGSRA
>Mature_537_residues
MKALVKNVDVVVVGAGFAGLYALQRLRSQGLSVVVFEAGSDVGGTWFFNRYPGARCDVESIDYSYSFSDELQQEWDWTEK
YAGQKEILRYINHVADRFDLRRDIRCGTRVTSAVFDEDQLRWTVRTDRNDTVSARFCVMATGALSTANMPTIPGRDAFTG
ELYHTGHWPASGVDFAGKRVGVIGTGSSGIQLVPIAAQTAKELFVFQRTANYTVPAGNTVISPERRAEVKANYAERRRQS
RESGGGSPHQAYPKKTLEISAAERRAAFERRWELGGVLFGKTFPDQTTDMRANNEARAFFEEKVRAVIHDPAIADILVPT
DHPIGTKRICTDTNYFQTFNRDNVHVVDLRAAPIESINRRGMTTTTKYYELDMIVFATGFDAMTGSLNRIDIRGRAGRPL
KDAWQAGPRTYLGLGVDGFPNLFVVTGPGSPSVLANMVLGAEQHVDWIGDLLDYMAAHGYSTVEAEPQAVADWVTECNER
AAATMFPQANSWYLGANIPGKPRVFMPFIGGFGVYGAICADVAASGYKGFTLAGSRA

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503755, Length=209, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI50541965, Length=218, Percent_Identity=27.0642201834862, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI50541961, Length=218, Percent_Identity=27.0642201834862, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4503757, Length=218, Percent_Identity=27.5229357798165, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI221316674, Length=230, Percent_Identity=29.1304347826087, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI221316672, Length=230, Percent_Identity=29.1304347826087, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI221316678, Length=230, Percent_Identity=29.1304347826087, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17541300, Length=229, Percent_Identity=26.6375545851528, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25145785, Length=207, Percent_Identity=25.1207729468599, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193202226, Length=212, Percent_Identity=25.9433962264151, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19921694, Length=248, Percent_Identity=28.6290322580645, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19922866, Length=211, Percent_Identity=29.3838862559242, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.92 [H]

Molecular weight: Translated: 59092; Mature: 59092

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVKNVDVVVVGAGFAGLYALQRLRSQGLSVVVFEAGSDVGGTWFFNRYPGARCDVES
CCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCHHH
IDYSYSFSDELQQEWDWTEKYAGQKEILRYINHVADRFDLRRDIRCGTRVTSAVFDEDQL
CCCEECCCHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCE
RWTVRTDRNDTVSARFCVMATGALSTANMPTIPGRDAFTGELYHTGHWPASGVDFAGKRV
EEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEE
GVIGTGSSGIQLVPIAAQTAKELFVFQRTANYTVPAGNTVISPERRAEVKANYAERRRQS
EEEECCCCCEEEEEEHHHHHHHHEEEEECCCEECCCCCEEECCHHHHHHHHHHHHHHHHH
RESGGGSPHQAYPKKTLEISAAERRAAFERRWELGGVLFGKTFPDQTTDMRANNEARAFF
HHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHH
EEKVRAVIHDPAIADILVPTDHPIGTKRICTDTNYFQTFNRDNVHVVDLRAAPIESINRR
HHHHHHHHCCCCEEEEEECCCCCCCCCEEECCCHHHHHCCCCCEEEEEECCCCHHHHHCC
GMTTTTKYYELDMIVFATGFDAMTGSLNRIDIRGRAGRPLKDAWQAGPRTYLGLGVDGFP
CCEEEEEEEEEEEEEEEECCHHHCCCCEEEEECCCCCCCHHHHHHCCCCEEEEECCCCCC
NLFVVTGPGSPSVLANMVLGAEQHVDWIGDLLDYMAAHGYSTVEAEPQAVADWVTECNER
CEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
AAATMFPQANSWYLGANIPGKPRVFMPFIGGFGVYGAICADVAASGYKGFTLAGSRA
HHEEECCCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure
MKALVKNVDVVVVGAGFAGLYALQRLRSQGLSVVVFEAGSDVGGTWFFNRYPGARCDVES
CCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCHHH
IDYSYSFSDELQQEWDWTEKYAGQKEILRYINHVADRFDLRRDIRCGTRVTSAVFDEDQL
CCCEECCCHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCE
RWTVRTDRNDTVSARFCVMATGALSTANMPTIPGRDAFTGELYHTGHWPASGVDFAGKRV
EEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEE
GVIGTGSSGIQLVPIAAQTAKELFVFQRTANYTVPAGNTVISPERRAEVKANYAERRRQS
EEEECCCCCEEEEEEHHHHHHHHEEEEECCCEECCCCCEEECCHHHHHHHHHHHHHHHHH
RESGGGSPHQAYPKKTLEISAAERRAAFERRWELGGVLFGKTFPDQTTDMRANNEARAFF
HHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHH
EEKVRAVIHDPAIADILVPTDHPIGTKRICTDTNYFQTFNRDNVHVVDLRAAPIESINRR
HHHHHHHHCCCCEEEEEECCCCCCCCCEEECCCHHHHHCCCCCEEEEEECCCCHHHHHCC
GMTTTTKYYELDMIVFATGFDAMTGSLNRIDIRGRAGRPLKDAWQAGPRTYLGLGVDGFP
CCEEEEEEEEEEEEEEEECCHHHCCCCEEEEECCCCCCCHHHHHHCCCCEEEEECCCCCC
NLFVVTGPGSPSVLANMVLGAEQHVDWIGDLLDYMAAHGYSTVEAEPQAVADWVTECNER
CEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
AAATMFPQANSWYLGANIPGKPRVFMPFIGGFGVYGAICADVAASGYKGFTLAGSRA
HHEEECCCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA