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The map label for this gene is sthA [H]

Identifier: 16767835

GI number: 16767835

Start: 4852095

End: 4852778

Strand: Reverse

Name: sthA [H]

Synonym: STM4594

Alternate gene names: 16767835

Gene position: 4852778-4852095 (Counterclockwise)

Preceding gene: 16767836

Following gene: 16767834

Centisome position: 99.9

GC content: 46.2

Gene sequence:

>684_bases
ATGAAACACATAAAGAAATCCGTGTTGGCCGTATTACTGACAAGCCATGTTGCCCATGCCAGCATTGTTGTTGGCGGAAC
CCGACTGGTTTTCGACGGCAATAATGATGAGTCGTCAATCAATGTAGAGAATAAAGACAGCAAAGCGAATCTTGTTCAGT
CATGGTTATCGGTTGCCGATCCCCAGGTCACAAATAAGCAGGCGTTTATTATCACCCCGCCTCTTTTTCGCCTTGATGCC
GGGCAAAAGAACAGTATTCGGGTTATTCGCTCTGGCGCCCCCCTACCTGCAGATCGGGAGTCTATGTACTGGCTCAATAT
TAAGGGTATTCCTTCTATTGATGATAATGCCTCCGCGAACCGCGTGGAAATCTCCATTAATACCCAAATAAAGCTTATAT
ATCGACCGCCAGCATTAACAAAATCAACGCCTGATAGCCAGAGCCAACAATTAAAATGGCAGACGGCAGGTGATGTTATT
ACCGTAAATAACCCCACTCCCTATTATATGAACTTTGCCAGTGTGACGCTTAACAGCCATGAAGTGAAATCAGCGACCTT
CGTTCCGCCAAAATCATCAGCGTCATTTAAATTGGGTTCTACTGCCGCCCCTCATGGCACGGTAACGTGGCGATTAATCA
GCGATTATGGGATGAGTTTAGAGCCGCATTCCGGTTCATTCTAG

Upstream 100 bases:

>100_bases
CAGGTTACGTATACCGTTTCGTATCAGTAAGGCATTCTCATCCTGATGTGGACAGGCAGGATGCCAGTCCATAGCGTAAA
ACATCTTTACAGAGTAAAAA

Downstream 100 bases:

>100_bases
CCATTAACGACTTCATTTTACTTTTACCCTTTCAGGACTTTTACTGTGCAATTCTCCAGAGTAGAGCCCCGTTCTCAATT
AGCGTTATCGTTTCTCTTTA

Product: fimbrial chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKHIKKSVLAVLLTSHVAHASIVVGGTRLVFDGNNDESSINVENKDSKANLVQSWLSVADPQVTNKQAFIITPPLFRLDA
GQKNSIRVIRSGAPLPADRESMYWLNIKGIPSIDDNASANRVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVI
TVNNPTPYYMNFASVTLNSHEVKSATFVPPKSSASFKLGSTAAPHGTVTWRLISDYGMSLEPHSGSF

Sequences:

>Translated_227_residues
MKHIKKSVLAVLLTSHVAHASIVVGGTRLVFDGNNDESSINVENKDSKANLVQSWLSVADPQVTNKQAFIITPPLFRLDA
GQKNSIRVIRSGAPLPADRESMYWLNIKGIPSIDDNASANRVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVI
TVNNPTPYYMNFASVTLNSHEVKSATFVPPKSSASFKLGSTAAPHGTVTWRLISDYGMSLEPHSGSF
>Mature_227_residues
MKHIKKSVLAVLLTSHVAHASIVVGGTRLVFDGNNDESSINVENKDSKANLVQSWLSVADPQVTNKQAFIITPPLFRLDA
GQKNSIRVIRSGAPLPADRESMYWLNIKGIPSIDDNASANRVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVI
TVNNPTPYYMNFASVTLNSHEVKSATFVPPKSSASFKLGSTAAPHGTVTWRLISDYGMSLEPHSGSF

Specific function: Required for the biogenesis of type 1 fimbriae. Binds and interact with fimH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1790771, Length=213, Percent_Identity=32.3943661971831, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1786743, Length=224, Percent_Identity=32.1428571428571, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789532, Length=219, Percent_Identity=31.0502283105023, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787171, Length=218, Percent_Identity=32.5688073394495, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786333, Length=218, Percent_Identity=31.1926605504587, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786936, Length=224, Percent_Identity=29.0178571428571, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI87081806, Length=217, Percent_Identity=30.8755760368664, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788677, Length=206, Percent_Identity=31.0679611650485, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1788428, Length=219, Percent_Identity=26.027397260274, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789609, Length=229, Percent_Identity=27.0742358078603, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082203, Length=234, Percent_Identity=25.6410256410256, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 24743; Mature: 24743

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIKKSVLAVLLTSHVAHASIVVGGTRLVFDGNNDESSINVENKDSKANLVQSWLSVAD
CCHHHHHHHHHHHHHHHCEEEEEECCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCC
PQVTNKQAFIITPPLFRLDAGQKNSIRVIRSGAPLPADRESMYWLNIKGIPSIDDNASAN
CCCCCCEEEEECCCCEEECCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCC
RVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVITVNNPTPYYMNFASVTLNSH
EEEEEECCEEEEEECCCCCCCCCCCCCHHEEEEEECCCEEEECCCCCEEEEEEEEEECCC
EVKSATFVPPKSSASFKLGSTAAPHGTVTWRLISDYGMSLEPHSGSF
CCCCEEECCCCCCCCEEECCCCCCCCCEEEEEEECCCCEECCCCCCC
>Mature Secondary Structure
MKHIKKSVLAVLLTSHVAHASIVVGGTRLVFDGNNDESSINVENKDSKANLVQSWLSVAD
CCHHHHHHHHHHHHHHHCEEEEEECCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCC
PQVTNKQAFIITPPLFRLDAGQKNSIRVIRSGAPLPADRESMYWLNIKGIPSIDDNASAN
CCCCCCEEEEECCCCEEECCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCC
RVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVITVNNPTPYYMNFASVTLNSH
EEEEEECCEEEEEECCCCCCCCCCCCCHHEEEEEECCCEEEECCCCCEEEEEEEEEECCC
EVKSATFVPPKSSASFKLGSTAAPHGTVTWRLISDYGMSLEPHSGSF
CCCCEEECCCCCCCCEEECCCCCCCCCEEEEEEECCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]