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The map label for this gene is glpD [H]

Identifier: 16766813

GI number: 16766813

Start: 3688731

End: 3690239

Strand: Direct

Name: glpD [H]

Synonym: STM3526

Alternate gene names: 16766813

Gene position: 3688731-3690239 (Clockwise)

Preceding gene: 16766809

Following gene: 16766817

Centisome position: 75.94

GC content: 55.86

Gene sequence:

>1509_bases
ATGGAAACCAAAGATCTGATCGTGATAGGCGGGGGCATTAACGGTGCAGGCATCGCGGCTGATGCCGCCGGGCGCGGTTT
GTCCGTACTCATGCTGGAAGCGCAGGATTTGGCCTGCGCAACCTCTTCCGCCAGTTCGAAACTTATCCACGGCGGCTTAC
GCTACCTTGAGCACTACGAGTTCCGTCTGGTCAGCGAAGCGCTGGCAGAACGTGAAGTGCTGTTGAAAATGGCGCCGCAC
ATCGCCTTCCCGATGCGTTTTCGTCTGCCGCACCGCCCGCATTTACGTCCGGCCTGGATGATCCGTATCGGTCTGTTTAT
GTACGATCACCTCGGCAAACGTACCAGTTTACCCGGTTCCACCGGTGTGCGGTTTGGCGCAGATTCGGTGCTCAAACCGG
AAATCGTGCGCGGATTCGAATATTCCGACTGCTGGGTAGACGATGCGCGTCTGGTGCTGGCTAACGCACAGATGGTGGTG
CGTAAAGGCGGCGAAGTCCTTACCCGTACTCGCGCAACCGCCGCTCGTCGGGAAAATGGCCTGTGGATTGTCGAAGCGGA
AGATATCGACACCGGTAAAAAATATGTCTGGCAGGCGCGCGGACTGGTTAACGCCACCGGACCGTGGGTCAAACAGTTCT
TCGACGAAGGGATGCACCTGCCGTCGCCATATGGCATCCGCCTGATCAAAGGCAGCCATATCGTCGTGCCGCGCGTCCAT
AATCAGAAGCAGGCGTATATTCTGCAAAACGAAGATAAGCGTATCGTCTTTGTCATTCCGTGGATGGAAGAGTTTTCGAT
CATTGGCACGACCGATGTCGAATATAAAGGCGATCCGAAAGCGGTAAAAATTGAAGAGAGCGAAATTAATTACCTGTTGA
AGGTTTATAACGCGCACTTCCAGAAACAACTGGGGCGCGATGACATCGTCTGGACGTACTCCGGCGTCCGTCCGCTGTGC
GATGATGAGTCCGACTCACCGCAGGCGATCACTCGCGATTATACCCTTGATATTCATGATGAAAACGGCAAAGCGCCGCT
GCTTTCCGTGTTTGGCGGTAAGCTCACGACCTACCGTAAGCTGGCTGAACACGCGATGGAAAAACTGGCGTCTTATTATC
CAGGCATCGGGCCGGCATGGACCAAAACGTGCGTACTGCCCGGCGGCGACATCGACGGCAGCCGCGAAGATTACGCGGCG
AAGCTGCGTCGTCGTTATCCGTTCCTGACGGAATCGCTGGCGCGCCACTATTCGCGCACTTACGGCAGCAACACGGAGTG
GATTCTCGGCGAAGCCACGTCGCTGCTTGATTTAGGCGAAGATTTCGGTCATGAGTTTTACGAGGCGGAACTCAAGTACC
TGGTGGATCACGAATGGGTGCGCCGTACTGAAGACGCTATCTGGCGTCGCACCAAAGAAGGCATGTGGCTGACCGCCGAA
CAGCAGTCCCGCATCACCCAGTGGCTGGCGGCGTATGTTGAGAAACACCAACTTTCAATGGCGTCGTAA

Upstream 100 bases:

>100_bases
ACTCTAAAATGTTTTTTCGATGTTACCAATAGCGCGTTTCTTTGCTATTATGTTCGATAACGAACATTTTTGAACTTTAA
CGAAAGTGCAAGAGGGCAGC

Downstream 100 bases:

>100_bases
TAAAATCCGGGGCGGTTTATACCGCCCTTTTCGCCACATACCGCATTCACTCGCCGGGTTTTGTACAGCCGGGCATATGA
TTAGTGATACGGTAGCGATC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPH
IAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGVRFGADSVLKPEIVRGFEYSDCWVDDARLVLANAQMVV
RKGGEVLTRTRATAARRENGLWIVEAEDIDTGKKYVWQARGLVNATGPWVKQFFDEGMHLPSPYGIRLIKGSHIVVPRVH
NQKQAYILQNEDKRIVFVIPWMEEFSIIGTTDVEYKGDPKAVKIEESEINYLLKVYNAHFQKQLGRDDIVWTYSGVRPLC
DDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRKLAEHAMEKLASYYPGIGPAWTKTCVLPGGDIDGSREDYAA
KLRRRYPFLTESLARHYSRTYGSNTEWILGEATSLLDLGEDFGHEFYEAELKYLVDHEWVRRTEDAIWRRTKEGMWLTAE
QQSRITQWLAAYVEKHQLSMAS

Sequences:

>Translated_502_residues
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPH
IAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGVRFGADSVLKPEIVRGFEYSDCWVDDARLVLANAQMVV
RKGGEVLTRTRATAARRENGLWIVEAEDIDTGKKYVWQARGLVNATGPWVKQFFDEGMHLPSPYGIRLIKGSHIVVPRVH
NQKQAYILQNEDKRIVFVIPWMEEFSIIGTTDVEYKGDPKAVKIEESEINYLLKVYNAHFQKQLGRDDIVWTYSGVRPLC
DDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRKLAEHAMEKLASYYPGIGPAWTKTCVLPGGDIDGSREDYAA
KLRRRYPFLTESLARHYSRTYGSNTEWILGEATSLLDLGEDFGHEFYEAELKYLVDHEWVRRTEDAIWRRTKEGMWLTAE
QQSRITQWLAAYVEKHQLSMAS
>Mature_502_residues
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPH
IAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGVRFGADSVLKPEIVRGFEYSDCWVDDARLVLANAQMVV
RKGGEVLTRTRATAARRENGLWIVEAEDIDTGKKYVWQARGLVNATGPWVKQFFDEGMHLPSPYGIRLIKGSHIVVPRVH
NQKQAYILQNEDKRIVFVIPWMEEFSIIGTTDVEYKGDPKAVKIEESEINYLLKVYNAHFQKQLGRDDIVWTYSGVRPLC
DDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRKLAEHAMEKLASYYPGIGPAWTKTCVLPGGDIDGSREDYAA
KLRRRYPFLTESLARHYSRTYGSNTEWILGEATSLLDLGEDFGHEFYEAELKYLVDHEWVRRTEDAIWRRTKEGMWLTAE
QQSRITQWLAAYVEKHQLSMAS

Specific function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor [H]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=508, Percent_Identity=31.2992125984252, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI285002231, Length=508, Percent_Identity=31.2992125984252, Blast_Score=173, Evalue=3e-43,
Organism=Escherichia coli, GI2367226, Length=502, Percent_Identity=90.4382470119522, Blast_Score=906, Evalue=0.0,
Organism=Escherichia coli, GI1788574, Length=470, Percent_Identity=25.7446808510638, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115534726, Length=514, Percent_Identity=30.5447470817121, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17509253, Length=522, Percent_Identity=28.544061302682, Blast_Score=155, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6322036, Length=532, Percent_Identity=27.2556390977444, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI161077125, Length=510, Percent_Identity=29.6078431372549, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24653942, Length=510, Percent_Identity=29.6078431372549, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24653944, Length=510, Percent_Identity=29.6078431372549, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI20130025, Length=510, Percent_Identity=29.6078431372549, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24586295, Length=498, Percent_Identity=27.5100401606426, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI19921278, Length=502, Percent_Identity=24.5019920318725, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56926; Mature: 56926

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYE
CCCCCEEEECCCCCCCCEECCCCCCCEEEEEEECCHHHEECCCCCHHHHHHHHHHHHHHH
FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGS
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
TGVRFGADSVLKPEIVRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATAARRENG
CCCCCCCCCCCCHHHHCCCCCCCCEECCCEEEEECCHHHHHCCCHHHHHHHHHHHHCCCC
LWIVEAEDIDTGKKYVWQARGLVNATGPWVKQFFDEGMHLPSPYGIRLIKGSHIVVPRVH
EEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCC
NQKQAYILQNEDKRIVFVIPWMEEFSIIGTTDVEYKGDPKAVKIEESEINYLLKVYNAHF
CCCEEEEEECCCCEEEEEECCHHHCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
QKQLGRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRK
HHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHCCCCHHHHHH
LAEHAMEKLASYYPGIGPAWTKTCVLPGGDIDGSREDYAAKLRRRYPFLTESLARHYSRT
HHHHHHHHHHHHCCCCCCCHHCEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
YGSNTEWILGEATSLLDLGEDFGHEFYEAELKYLVDHEWVRRTEDAIWRRTKEGMWLTAE
CCCCCCEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEH
QQSRITQWLAAYVEKHQLSMAS
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYE
CCCCCEEEECCCCCCCCEECCCCCCCEEEEEEECCHHHEECCCCCHHHHHHHHHHHHHHH
FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGS
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
TGVRFGADSVLKPEIVRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATAARRENG
CCCCCCCCCCCCHHHHCCCCCCCCEECCCEEEEECCHHHHHCCCHHHHHHHHHHHHCCCC
LWIVEAEDIDTGKKYVWQARGLVNATGPWVKQFFDEGMHLPSPYGIRLIKGSHIVVPRVH
EEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCC
NQKQAYILQNEDKRIVFVIPWMEEFSIIGTTDVEYKGDPKAVKIEESEINYLLKVYNAHF
CCCEEEEEECCCCEEEEEECCHHHCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
QKQLGRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRK
HHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHCCCCHHHHHH
LAEHAMEKLASYYPGIGPAWTKTCVLPGGDIDGSREDYAAKLRRRYPFLTESLARHYSRT
HHHHHHHHHHHHCCCCCCCHHCEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
YGSNTEWILGEATSLLDLGEDFGHEFYEAELKYLVDHEWVRRTEDAIWRRTKEGMWLTAE
CCCCCCEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEH
QQSRITQWLAAYVEKHQLSMAS
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987111; 9278503; 3045087; 3045764 [H]