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The map label for this gene is cadC [H]

Identifier: 16765877

GI number: 16765877

Start: 2696631

End: 2698175

Strand: Direct

Name: cadC [H]

Synonym: STM2557

Alternate gene names: 16765877

Gene position: 2696631-2698175 (Clockwise)

Preceding gene: 16765876

Following gene: 16765878

Centisome position: 55.52

GC content: 47.64

Gene sequence:

>1545_bases
ATGCAGCAACCTGTTGTACGCATTGGAGAGTGGCTGGTTACACCTTCTGTTAATCAGATCAGTCGTCAGGGACGCCAGAT
TACTCTTGAACCACGGCTGATCGATCTTCTGATGTATTTTGCGCATCACCCGGATGAAGTGTTAAGCCGGGATAACATTA
TTGATCATGTCTGGATGCGCACCATCGTGACCAACCATGTTGTCACCCAAAGCATTTCTGAACTACGCAAATCATTAAGA
GATGGCGGAGACAGCAATGCTGAATACATCGTTACCGTACCTAAACGCGGCTATAAGCTGACGGCGCCGGTTATCTGGTG
CGAAGAAAATAGCGATGAGATCGATAATTCATCAACGTCGCCGCCGCCGCCGATCGCAGCGACGAATGCAGAACCGACGG
AGGGGGTTACTGCCGCTACGCCTGTGCCGCCCGCCTCTTTGCAAACGCCGACTAAAAAGGCGAAAAAGCCGCGTATTGCC
GCTTTCTGGACGTGGGTGATGTTCCTGCTCTCGCTGGCGACGCTGGTGGTGTTTATCGTGATGTCGGTGGTAGATCATAA
TGCCGCGGTAACAAAAACGCGGTTATTACTTAACCCACGAGATATAGATGTTCGTTTTGAAGGCGGCAATTCCTGTAATA
ACTGGGTCTCGCAGGAGTCCTACGCCATCGGTCTGGGCGGCTTAATCACCGACCTGCTGAACACCTACTCGACTTTTATG
GTGCACGATAAAACCAATTACCGGGTCAATGAGCCAAGCAGCTCCGGTAAGACGTTAACCATTCAGTTTGTCAATCAGCG
CCACTATCGGGCGCAGCAGTGCTTTATGTCTGTAGTGCTCATTGATAACGCCGATGGTTCAACCATGCTGGATAAGCGTT
ATTTCGTCACCAATACTAACCAGTTGTCCATCCAGGATGATCTGTTTAATAGCCTGTCTTTCGTTTTAACACAGCCCTGG
CCTAATCGTATGCGAGAACAACTGGCCCTGTTCAGAACGCCGCAAAATACCGCACTGATGCGTTTTTATGAGGCGCGCCA
GCTTATTCTGAGCGGCGATGCGCAGGCGCTAGGTAAAGCCAGCGATATTCTGAATGGCATTATTAAGGAAACGCCTGATT
TCAACTATGCCTATGAATATAAAGTGCTGGTAGATGTATTACGGCAATCACAGCAGCCGTTTGATAAAGAACAAGTGGCC
GCACTGAACGAAGAGTTTAAAAAAATAGATCAAATTCCGGGCGTTGAGAAAACGTCTGTTTATTATAAAATCAAGACCGT
CGATCTGTTAGGCAAAGGTGATATCGATGCAGCGTATGAGGAAATCAATAAAAGCATCGAGCTTGAAATGTCGTGGTTTA
ACTATGTCCTGTTGGGGAAAGTTTACGAAATGAAAGGTGAGAATCGTCTGGCCGCTGATGCCTATCTGACCGCCTTTAAT
TTACGTCCAGGTGAAAACACTCTGTACTGGATCGAGAACGGCGTATTTCAGACATCCGTTCAGAAAATTGTCCCTTATCT
GAATAGTTTTCTGGCAGAAGATTAA

Upstream 100 bases:

>100_bases
TGCTTTTTATGCCTTTCTTTTACAAAAAAGGGGAATAAAAAAAGTCTGTGCAAATCGTGTTATTATTAACGTTTGACTTA
GCTCGTTAGGGCATCTTTTT

Downstream 100 bases:

>100_bases
ATTTAACGCTGAACCATGACAAATAAAAGCGAAAAGATATTAAATTTTTCGCTTTTATTTTGTGAAAAACATGTTGCCAA
AAATAGCTTATGTTAATTTT

Product: DNA-binding transcriptional activator CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHPDEVLSRDNIIDHVWMRTIVTNHVVTQSISELRKSLR
DGGDSNAEYIVTVPKRGYKLTAPVIWCEENSDEIDNSSTSPPPPIAATNAEPTEGVTAATPVPPASLQTPTKKAKKPRIA
AFWTWVMFLLSLATLVVFIVMSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQESYAIGLGGLITDLLNTYSTFM
VHDKTNYRVNEPSSSGKTLTIQFVNQRHYRAQQCFMSVVLIDNADGSTMLDKRYFVTNTNQLSIQDDLFNSLSFVLTQPW
PNRMREQLALFRTPQNTALMRFYEARQLILSGDAQALGKASDILNGIIKETPDFNYAYEYKVLVDVLRQSQQPFDKEQVA
ALNEEFKKIDQIPGVEKTSVYYKIKTVDLLGKGDIDAAYEEINKSIELEMSWFNYVLLGKVYEMKGENRLAADAYLTAFN
LRPGENTLYWIENGVFQTSVQKIVPYLNSFLAED

Sequences:

>Translated_514_residues
MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHPDEVLSRDNIIDHVWMRTIVTNHVVTQSISELRKSLR
DGGDSNAEYIVTVPKRGYKLTAPVIWCEENSDEIDNSSTSPPPPIAATNAEPTEGVTAATPVPPASLQTPTKKAKKPRIA
AFWTWVMFLLSLATLVVFIVMSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQESYAIGLGGLITDLLNTYSTFM
VHDKTNYRVNEPSSSGKTLTIQFVNQRHYRAQQCFMSVVLIDNADGSTMLDKRYFVTNTNQLSIQDDLFNSLSFVLTQPW
PNRMREQLALFRTPQNTALMRFYEARQLILSGDAQALGKASDILNGIIKETPDFNYAYEYKVLVDVLRQSQQPFDKEQVA
ALNEEFKKIDQIPGVEKTSVYYKIKTVDLLGKGDIDAAYEEINKSIELEMSWFNYVLLGKVYEMKGENRLAADAYLTAFN
LRPGENTLYWIENGVFQTSVQKIVPYLNSFLAED
>Mature_514_residues
MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHPDEVLSRDNIIDHVWMRTIVTNHVVTQSISELRKSLR
DGGDSNAEYIVTVPKRGYKLTAPVIWCEENSDEIDNSSTSPPPPIAATNAEPTEGVTAATPVPPASLQTPTKKAKKPRIA
AFWTWVMFLLSLATLVVFIVMSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQESYAIGLGGLITDLLNTYSTFM
VHDKTNYRVNEPSSSGKTLTIQFVNQRHYRAQQCFMSVVLIDNADGSTMLDKRYFVTNTNQLSIQDDLFNSLSFVLTQPW
PNRMREQLALFRTPQNTALMRFYEARQLILSGDAQALGKASDILNGIIKETPDFNYAYEYKVLVDVLRQSQQPFDKEQVA
ALNEEFKKIDQIPGVEKTSVYYKIKTVDLLGKGDIDAAYEEINKSIELEMSWFNYVLLGKVYEMKGENRLAADAYLTAFN
LRPGENTLYWIENGVFQTSVQKIVPYLNSFLAED

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=518, Percent_Identity=58.6872586872587, Blast_Score=594, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 58232; Mature: 58232

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHPDEVLSRDNIIDHVWMR
CCCCHHHHCCEEECCCHHHHHHCCCEEEECHHHHHHHHHHHCCCHHHHHHCCHHHHHHHH
TIVTNHVVTQSISELRKSLRDGGDSNAEYIVTVPKRGYKLTAPVIWCEENSDEIDNSSTS
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCEEEECCCCCCCCCCCCC
PPPPIAATNAEPTEGVTAATPVPPASLQTPTKKAKKPRIAAFWTWVMFLLSLATLVVFIV
CCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
MSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQESYAIGLGGLITDLLNTYSTFM
HHHHCCCCHHEEEEEEECCCCEEEEECCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHEEE
VHDKTNYRVNEPSSSGKTLTIQFVNQRHYRAQQCFMSVVLIDNADGSTMLDKRYFVTNTN
EECCCCCEECCCCCCCCEEEEEEECCHHHHHHHHHEEEEEEECCCCCCEECCEEEEECCC
QLSIQDDLFNSLSFVLTQPWPNRMREQLALFRTPQNTALMRFYEARQLILSGDAQALGKA
EEEEHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
SDILNGIIKETPDFNYAYEYKVLVDVLRQSQQPFDKEQVAALNEEFKKIDQIPGVEKTSV
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
YYKIKTVDLLGKGDIDAAYEEINKSIELEMSWFNYVLLGKVYEMKGENRLAADAYLTAFN
EEEEEEEEEECCCCHHHHHHHCCCCEEEEEHHHHEEHHHHHHHHCCCCCEEHHHEEEEEE
LRPGENTLYWIENGVFQTSVQKIVPYLNSFLAED
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHPDEVLSRDNIIDHVWMR
CCCCHHHHCCEEECCCHHHHHHCCCEEEECHHHHHHHHHHHCCCHHHHHHCCHHHHHHHH
TIVTNHVVTQSISELRKSLRDGGDSNAEYIVTVPKRGYKLTAPVIWCEENSDEIDNSSTS
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCEEEECCCCCCCCCCCCC
PPPPIAATNAEPTEGVTAATPVPPASLQTPTKKAKKPRIAAFWTWVMFLLSLATLVVFIV
CCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
MSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQESYAIGLGGLITDLLNTYSTFM
HHHHCCCCHHEEEEEEECCCCEEEEECCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHEEE
VHDKTNYRVNEPSSSGKTLTIQFVNQRHYRAQQCFMSVVLIDNADGSTMLDKRYFVTNTN
EECCCCCEECCCCCCCCEEEEEEECCHHHHHHHHHEEEEEEECCCCCCEECCEEEEECCC
QLSIQDDLFNSLSFVLTQPWPNRMREQLALFRTPQNTALMRFYEARQLILSGDAQALGKA
EEEEHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
SDILNGIIKETPDFNYAYEYKVLVDVLRQSQQPFDKEQVAALNEEFKKIDQIPGVEKTSV
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
YYKIKTVDLLGKGDIDAAYEEINKSIELEMSWFNYVLLGKVYEMKGENRLAADAYLTAFN
EEEEEEEEEECCCCHHHHHHHCCCCEEEEEHHHHEEHHHHHHHHCCCCCEEHHHEEEEEE
LRPGENTLYWIENGVFQTSVQKIVPYLNSFLAED
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]