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The map label for this gene is serB [C]

Identifier: 16765527

GI number: 16765527

Start: 2294265

End: 2295152

Strand: Direct

Name: serB [C]

Synonym: STM2197

Alternate gene names: 16765527

Gene position: 2294265-2295152 (Clockwise)

Preceding gene: 16765524

Following gene: 16765528

Centisome position: 47.23

GC content: 44.59

Gene sequence:

>888_bases
ATGAGCATTATTTATTTTATTACTACACAGGATATCGATACGTTTCAGAAAAAATTACAGGAAACGTTATTTAATGCCGT
CACCATGCCGTTTCCGCTATTATTTGATAAACGTTATGCCGCGCTTATCAATACCGCTTATTTAAAGCTTACGCTGCCAG
CGGAATGTCTGACGCCTGAATTTTATCGCTATTTACGCGAACTCTCATTGCAATGGCAGTTTGATTTTTTTATTAAGCCG
CAGCCACTGCCTGCTAACGGTATTATCGCGTTTGATATGGACTCGACATTTATTGCGGAAGAAGGCGTGGATGAAATTGC
CCGCGAGCTTGGCATGTCGACGCAAATCACCGCCATTACCCAACAGGCGATGGAGGGCAAGCTTGATTTTAACGCCAGTT
TTACCCGACGTATCGGAATGTTGAAAGGCACACCGAAAGCAGTGCTGAACGCCGTATGCGATCGCATGACCCTTTCGCCA
GGCCTGTTAACTATTCTGCCAGTCATCAAGGCCAAAGGATTTAAAACCGCGATTATCTCCGGGGGACTGGATATATTCAC
CCAGCGTCTAAAAGAACGGTATCAACTGGATTATGCCTTTTCGAATACGGTTGAAATACGCGATAACGTTCTGACGGATA
ACATTACCTTGCCGATTATGAACGCCGCAAACAAAAAACAGACGCTGGTTGACCTGGCTGCCCGGTTAAATATTGCCACG
GAGAATATTATTGCCTGCGGTGATGGCGCCAACGATCTGCCGATGTTAGAACATGCTGGCACCGGTATTGCCTGGAAAGC
GAAGCCGGTTGTACGGAAAAAAATCCACCATCAGATTAATTATCACGGTTTCGAATTGCTTCTTTTTCTTATTGAAGATG
AATTATAA

Upstream 100 bases:

>100_bases
CGCTTTTTTAGCCCTTTTCTGGCTGTGATATCTGTGATAGCACGAGATTCCACGCCGCAAAAGAGCCATTATAATACCCG
TAAATTAAGGGAGTTATCAT

Downstream 100 bases:

>100_bases
CGCGACTCACCTCGCCGGAAGGGAATTTTAAAATGAGTATAAAAACATTTATTTTCAGCCAGCCCGATAAGCCGATTGTA
AAAGAGAAAAAAGAGATAGA

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSIIYFITTQDIDTFQKKLQETLFNAVTMPFPLLFDKRYAALINTAYLKLTLPAECLTPEFYRYLRELSLQWQFDFFIKP
QPLPANGIIAFDMDSTFIAEEGVDEIARELGMSTQITAITQQAMEGKLDFNASFTRRIGMLKGTPKAVLNAVCDRMTLSP
GLLTILPVIKAKGFKTAIISGGLDIFTQRLKERYQLDYAFSNTVEIRDNVLTDNITLPIMNAANKKQTLVDLAARLNIAT
ENIIACGDGANDLPMLEHAGTGIAWKAKPVVRKKIHHQINYHGFELLLFLIEDEL

Sequences:

>Translated_295_residues
MSIIYFITTQDIDTFQKKLQETLFNAVTMPFPLLFDKRYAALINTAYLKLTLPAECLTPEFYRYLRELSLQWQFDFFIKP
QPLPANGIIAFDMDSTFIAEEGVDEIARELGMSTQITAITQQAMEGKLDFNASFTRRIGMLKGTPKAVLNAVCDRMTLSP
GLLTILPVIKAKGFKTAIISGGLDIFTQRLKERYQLDYAFSNTVEIRDNVLTDNITLPIMNAANKKQTLVDLAARLNIAT
ENIIACGDGANDLPMLEHAGTGIAWKAKPVVRKKIHHQINYHGFELLLFLIEDEL
>Mature_294_residues
SIIYFITTQDIDTFQKKLQETLFNAVTMPFPLLFDKRYAALINTAYLKLTLPAECLTPEFYRYLRELSLQWQFDFFIKPQ
PLPANGIIAFDMDSTFIAEEGVDEIARELGMSTQITAITQQAMEGKLDFNASFTRRIGMLKGTPKAVLNAVCDRMTLSPG
LLTILPVIKAKGFKTAIISGGLDIFTQRLKERYQLDYAFSNTVEIRDNVLTDNITLPIMNAANKKQTLVDLAARLNIATE
NIIACGDGANDLPMLEHAGTGIAWKAKPVVRKKIHHQINYHGFELLLFLIEDEL

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=211, Percent_Identity=23.696682464455, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1790849, Length=195, Percent_Identity=39.4871794871795, Blast_Score=143, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6321647, Length=209, Percent_Identity=33.0143540669856, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24661601, Length=208, Percent_Identity=27.4038461538462, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 33245; Mature: 33114

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIIYFITTQDIDTFQKKLQETLFNAVTMPFPLLFDKRYAALINTAYLKLTLPAECLTPE
CEEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEECCHHHCCHH
FYRYLRELSLQWQFDFFIKPQPLPANGIIAFDMDSTFIAEEGVDEIARELGMSTQITAIT
HHHHHHHCCCEEEEEEEECCCCCCCCCEEEEECCCCHHHHCCHHHHHHHHCCCCHHHHHH
QQAMEGKLDFNASFTRRIGMLKGTPKAVLNAVCDRMTLSPGLLTILPVIKAKGFKTAIIS
HHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEC
GGLDIFTQRLKERYQLDYAFSNTVEIRDNVLTDNITLPIMNAANKKQTLVDLAARLNIAT
CCHHHHHHHHHHHHHHHEEECCEEEECCCEEECCEEEEEECCCCHHHHHHHHHHHHCCCC
ENIIACGDGANDLPMLEHAGTGIAWKAKPVVRKKIHHQINYHGFELLLFLIEDEL
CCEEEECCCCCCCCHHHHCCCCCEEECCHHHHHHHHHHCCCCHHHHEEEEHHCCC
>Mature Secondary Structure 
SIIYFITTQDIDTFQKKLQETLFNAVTMPFPLLFDKRYAALINTAYLKLTLPAECLTPE
EEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEECCHHHCCHH
FYRYLRELSLQWQFDFFIKPQPLPANGIIAFDMDSTFIAEEGVDEIARELGMSTQITAIT
HHHHHHHCCCEEEEEEEECCCCCCCCCEEEEECCCCHHHHCCHHHHHHHHCCCCHHHHHH
QQAMEGKLDFNASFTRRIGMLKGTPKAVLNAVCDRMTLSPGLLTILPVIKAKGFKTAIIS
HHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEC
GGLDIFTQRLKERYQLDYAFSNTVEIRDNVLTDNITLPIMNAANKKQTLVDLAARLNIAT
CCHHHHHHHHHHHHHHHEEECCEEEECCCEEECCEEEEEECCCCHHHHHHHHHHHHCCCC
ENIIACGDGANDLPMLEHAGTGIAWKAKPVVRKKIHHQINYHGFELLLFLIEDEL
CCEEEECCCCCCCCHHHHCCCCCEEECCHHHHHHHHHHCCCCHHHHEEEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]