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The map label for this gene is uhpC [H]

Identifier: 16765528

GI number: 16765528

Start: 2295185

End: 2296507

Strand: Direct

Name: uhpC [H]

Synonym: STM2198

Alternate gene names: 16765528

Gene position: 2295185-2296507 (Clockwise)

Preceding gene: 16765527

Following gene: 16765532

Centisome position: 47.25

GC content: 51.02

Gene sequence:

>1323_bases
ATGAGTATAAAAACATTTATTTTCAGCCAGCCCGATAAGCCGATTGTAAAAGAGAAAAAAGAGATAGACCAGACCTATAA
AAAATTTCGTTTTGAGATTATCGCCTCGGTCTTTATCTCTTATGCCGTCTTTTATCTTACCCGTAAAAACTTCTCCGCCG
CGATGCCGGCCATGCTGACGGAAACGTCGCTGACCGCAGAAGACTTCGCCATTATGTCTTCTATTTTTTACATTCTTTAT
GGCGCGATGAAGTTTGTCGGCGGGATGCTGGTCGATAAAATTAACCCGAAAGCCATGACCGGCCCGGTGCTGATTGGCGT
GGGGATTGTAAATATTCTGTTCGGCTTTTCCGACAGCGTGGCGGCATTCTACGTGCTGTACAGTCTCAACGCGATATTAC
AGGGCACCAGCTTTCCGCCGATGGCGAAAATTATGGCCTCGTGGTTTTCGAAAAACGAACGGGGACGCTGGTGGGCTATC
GTTGAAGCGGCGCACAATATCGGCGGCAGCCTCGCGCCGCTGCTGACCAGTTTTGCTATCGCCTTTAGCGGTAGCTGGAA
AATGGGATTTTATGTTCCCGGCGCCATTTCGCTGCTGATGGGGATAGTGGCGCTATTTACCATTAAAGATCGTCCCGGTA
CGTTAGGTTTGCCCAACGTGGGGCAGTGGCGTAACGACCCGACGGAACTGGCCCAGGTCAAGGCCAGCCCGGTCAACCTG
AGCTTCTGGCAGATTTTTGTGAAATATATCCTGACCAATCCACTGGTATGGATCATTATTATCGGTGATATGTCGGTTTA
TATTGCGCGCACTATCCTTAACGACTGGCCGCAGATTTACTATTCGCAGGTTCACGGCTGGAGCCTGATAAAAGCGAACT
CGATTATTTCCTGGTTTGAGGCGGGCGGACTGGCAGGTGGGTTGCTGGCAGGCTACTTGTCTGACTTTATGTTCAAAAGT
AACCGCTGGATGACCGGATTAATCTTCGCGTTAGCGCTGTGCATATGCATCGTGCTGGTGCCGCTGGTTCAGGATACCTC
TTACACCCTCACCGCGATTCTGTTCACCATCATGGGCTTCGCCTTATACGGACCGCATATGCTTTTTGCCGTCGGCTGTC
TGGATGTGACCCATAAGGATGCGGCGGGATCGATTACCGGCTTTCGGGGATTGTTCAGCTATGTCGGCGCGGCAATGGCC
GGTGTGCCGGTAATTATGGTGAAAAATAGCTGGGCGTGGTCGGGCGTTTATATCTATGCGGTGATCGCCATTCTGCTAAC
GACTCTGTCGCTGGCGCTGCTCTCCAGGCTGCATCGGTTATAA

Upstream 100 bases:

>100_bases
AAATCCACCATCAGATTAATTATCACGGTTTCGAATTGCTTCTTTTTCTTATTGAAGATGAATTATAACGCGACTCACCT
CGCCGGAAGGGAATTTTAAA

Downstream 100 bases:

>100_bases
CATTCTGGCGACAGCGGCAAAACGCGGCTGTCGCCAGTCTCTGTCAGAAACGGTAATCCACCGCCATAAAGTAACGACGT
CCGTCTTCGGTATAACCGTA

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSIKTFIFSQPDKPIVKEKKEIDQTYKKFRFEIIASVFISYAVFYLTRKNFSAAMPAMLTETSLTAEDFAIMSSIFYILY
GAMKFVGGMLVDKINPKAMTGPVLIGVGIVNILFGFSDSVAAFYVLYSLNAILQGTSFPPMAKIMASWFSKNERGRWWAI
VEAAHNIGGSLAPLLTSFAIAFSGSWKMGFYVPGAISLLMGIVALFTIKDRPGTLGLPNVGQWRNDPTELAQVKASPVNL
SFWQIFVKYILTNPLVWIIIIGDMSVYIARTILNDWPQIYYSQVHGWSLIKANSIISWFEAGGLAGGLLAGYLSDFMFKS
NRWMTGLIFALALCICIVLVPLVQDTSYTLTAILFTIMGFALYGPHMLFAVGCLDVTHKDAAGSITGFRGLFSYVGAAMA
GVPVIMVKNSWAWSGVYIYAVIAILLTTLSLALLSRLHRL

Sequences:

>Translated_440_residues
MSIKTFIFSQPDKPIVKEKKEIDQTYKKFRFEIIASVFISYAVFYLTRKNFSAAMPAMLTETSLTAEDFAIMSSIFYILY
GAMKFVGGMLVDKINPKAMTGPVLIGVGIVNILFGFSDSVAAFYVLYSLNAILQGTSFPPMAKIMASWFSKNERGRWWAI
VEAAHNIGGSLAPLLTSFAIAFSGSWKMGFYVPGAISLLMGIVALFTIKDRPGTLGLPNVGQWRNDPTELAQVKASPVNL
SFWQIFVKYILTNPLVWIIIIGDMSVYIARTILNDWPQIYYSQVHGWSLIKANSIISWFEAGGLAGGLLAGYLSDFMFKS
NRWMTGLIFALALCICIVLVPLVQDTSYTLTAILFTIMGFALYGPHMLFAVGCLDVTHKDAAGSITGFRGLFSYVGAAMA
GVPVIMVKNSWAWSGVYIYAVIAILLTTLSLALLSRLHRL
>Mature_439_residues
SIKTFIFSQPDKPIVKEKKEIDQTYKKFRFEIIASVFISYAVFYLTRKNFSAAMPAMLTETSLTAEDFAIMSSIFYILYG
AMKFVGGMLVDKINPKAMTGPVLIGVGIVNILFGFSDSVAAFYVLYSLNAILQGTSFPPMAKIMASWFSKNERGRWWAIV
EAAHNIGGSLAPLLTSFAIAFSGSWKMGFYVPGAISLLMGIVALFTIKDRPGTLGLPNVGQWRNDPTELAQVKASPVNLS
FWQIFVKYILTNPLVWIIIIGDMSVYIARTILNDWPQIYYSQVHGWSLIKANSIISWFEAGGLAGGLLAGYLSDFMFKSN
RWMTGLIFALALCICIVLVPLVQDTSYTLTAILFTIMGFALYGPHMLFAVGCLDVTHKDAAGSITGFRGLFSYVGAAMAG
VPVIMVKNSWAWSGVYIYAVIAILLTTLSLALLSRLHRL

Specific function: UhpC is required for uhpT expression, it may act jointly with the uhpB signaling protein [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=425, Percent_Identity=30.1176470588235, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI4503847, Length=425, Percent_Identity=30.1176470588235, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI256219483, Length=425, Percent_Identity=30.1176470588235, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI256219543, Length=447, Percent_Identity=29.3064876957494, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI256219564, Length=345, Percent_Identity=30.1449275362319, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI46361976, Length=494, Percent_Identity=20.6477732793522, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI87082310, Length=426, Percent_Identity=39.906103286385, Blast_Score=343, Evalue=2e-95,
Organism=Escherichia coli, GI1788573, Length=428, Percent_Identity=32.2429906542056, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI2367259, Length=415, Percent_Identity=27.9518072289157, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789515, Length=371, Percent_Identity=27.7628032345013, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI2367379, Length=397, Percent_Identity=21.6624685138539, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17542316, Length=445, Percent_Identity=22.9213483146067, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI133901854, Length=459, Percent_Identity=21.7864923747277, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI133901856, Length=459, Percent_Identity=21.7864923747277, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI133930953, Length=462, Percent_Identity=23.5930735930736, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564202, Length=331, Percent_Identity=22.9607250755287, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=261, Percent_Identity=23.7547892720307, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24656866, Length=397, Percent_Identity=20.4030226700252, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550478, Length=397, Percent_Identity=20.4030226700252, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24656861, Length=397, Percent_Identity=20.4030226700252, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48512; Mature: 48381

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKTFIFSQPDKPIVKEKKEIDQTYKKFRFEIIASVFISYAVFYLTRKNFSAAMPAMLT
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHH
ETSLTAEDFAIMSSIFYILYGAMKFVGGMLVDKINPKAMTGPVLIGVGIVNILFGFSDSV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHH
AAFYVLYSLNAILQGTSFPPMAKIMASWFSKNERGRWWAIVEAAHNIGGSLAPLLTSFAI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHH
AFSGSWKMGFYVPGAISLLMGIVALFTIKDRPGTLGLPNVGQWRNDPTELAQVKASPVNL
HCCCCCEEEEECCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCH
SFWQIFVKYILTNPLVWIIIIGDMSVYIARTILNDWPQIYYSQVHGWSLIKANSIISWFE
HHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
AGGLAGGLLAGYLSDFMFKSNRWMTGLIFALALCICIVLVPLVQDTSYTLTAILFTIMGF
HCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ALYGPHMLFAVGCLDVTHKDAAGSITGFRGLFSYVGAAMAGVPVIMVKNSWAWSGVYIYA
HHHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
VIAILLTTLSLALLSRLHRL
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIKTFIFSQPDKPIVKEKKEIDQTYKKFRFEIIASVFISYAVFYLTRKNFSAAMPAMLT
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHH
ETSLTAEDFAIMSSIFYILYGAMKFVGGMLVDKINPKAMTGPVLIGVGIVNILFGFSDSV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHH
AAFYVLYSLNAILQGTSFPPMAKIMASWFSKNERGRWWAIVEAAHNIGGSLAPLLTSFAI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHH
AFSGSWKMGFYVPGAISLLMGIVALFTIKDRPGTLGLPNVGQWRNDPTELAQVKASPVNL
HCCCCCEEEEECCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCH
SFWQIFVKYILTNPLVWIIIIGDMSVYIARTILNDWPQIYYSQVHGWSLIKANSIISWFE
HHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
AGGLAGGLLAGYLSDFMFKSNRWMTGLIFALALCICIVLVPLVQDTSYTLTAILFTIMGF
HCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ALYGPHMLFAVGCLDVTHKDAAGSITGFRGLFSYVGAAMAGVPVIMVKNSWAWSGVYIYA
HHHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
VIAILLTTLSLALLSRLHRL
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1569007; 11677609 [H]