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The map label for this gene is baeS [H]

Identifier: 16765460

GI number: 16765460

Start: 2223137

End: 2224540

Strand: Direct

Name: baeS [H]

Synonym: STM2130

Alternate gene names: 16765460

Gene position: 2223137-2224540 (Clockwise)

Preceding gene: 16765459

Following gene: 16765461

Centisome position: 45.77

GC content: 56.62

Gene sequence:

>1404_bases
ATGAAAGTCTGGCGGCCCGGAATCACCGGCAAGCTGTTTCTGGCGATCTTCGCCACCTGCATCGTGCTGCTGATCAGTAT
GCATTGGGCCGTGCGCGTCAGTTTTGAACGCGGATTTATTGACTATATCAAACACGGCAACGAGCAGCGGCTACAAATGC
TGGGCGATGCGCTGGGCGACCAGTACCAGCAACACGGCAACTGGCGTTTTTTACGCAACAACGATCGCTTCGTTTTCCAG
ATTTTGCGTTCATTTGAGCATGACAACGACCGCGATAAACCCGGCCCCGGTATGCCGCCGCACGGTTGGCGCACCCAATT
CTGGGTCGTCGATCAAAATGGCCGGGTACTGGTCGGCCCACGCGGTCCGGTGCCGCATGACGGTACTCGCCGTCCCATTC
TGGTCAATGACGTCGAAGTCGGCGCGATTATCGCCTCTCCTGTCGAGCGGCTGACGCGCAATACGGATATTAATTTTGAT
ATGCAGCAGCGGCGCGCCAGTTGGATGATCGTGGCGTTATCAACGTTGCTGGCCGCGCTGGCGACATTTTTGCTGGCGCG
TGGCCTGCTCGCCCCGGTCAAACGGTTGGTCGAAGGTACGCACAGACTGGCGGCGGGGGATTTTACCACGCGCGTGACTC
CAACCAGCGCTGATGAGCTGGGAAAACTGGCGCAGGACTTTAACCAGCTTGCCAGCACGCTGGAAAAAAACCAGCAGATG
CGCCGCGACTTTATGGCGGATATTTCCCACGAACTGCGCACGCCGCTGGCGGTATTGCGCGGCGAACTTGAAGCCATTCA
GGATGGCGTTCGCCAGTTCACGCCAGAATCGGTTACCTCGCTACAGGCGGAAGTCGGTACGCTTACCAAACTGGTTGACG
ACCTGCATCAGCTGTCGTTGTCTGACGAGGGCGCGCTGGCTTACCAAAAAACGACCGTCGATCTTGTTCCCCTGTTGGAA
GTCGCTGGCGGCGCGTTCAGAGAGCGCTTTACCAGCCGGGGGCTAACGCTACATTACGCGTTGCCGGATAGTATGACCGT
CTTCGGCGACCCGGATCGCCTGATGCAACTGTTTAATAATCTACTGGAAAACAGTCTGCGCTACACCGACAGCGGCGGCG
GCCTGCATATTTCCGCCGAACAACGCGACAAATCATTATTCCTGACCTTTGCCGATTCTGCACCGGGCGTCAGCGATGAA
CAGTTACAAAAGCTTTTTGACCGTTTTTACCGCACGGAAGTGTCCCGTAACCGCGCCAGCGGCGGTTCTGGACTGGGGCT
GGCAATATGCGTCAATATTGTACACGCGCATAACGGTCATCTTCACGCCGCTCATTCGCCTTTTGGCGGGGTTAGCATTA
CAGTAGAGTTACCGCTGGATCGCGATTTACAGAGAGAAGTATGA

Upstream 100 bases:

>100_bases
GTATGGCGGTTATTATCGCGCTACCGGCGATAATTTTTGCCCGCGTGCCGAACGATACACAGCAAAACATGGTCATTTCA
CGGCGTAAAAGGAGCCTGTA

Downstream 100 bases:

>100_bases
CTGAATTACCCATTGATGAAAACACGCCGCGCATTTTGATTGTTGAAGATGAACCCAAGCTGGGACAGCTGCTTATTGAC
TACTTACGCGCGGCGAGTTA

Product: signal transduction histidine-protein kinase BaeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKVWRPGITGKLFLAIFATCIVLLISMHWAVRVSFERGFIDYIKHGNEQRLQMLGDALGDQYQQHGNWRFLRNNDRFVFQ
ILRSFEHDNDRDKPGPGMPPHGWRTQFWVVDQNGRVLVGPRGPVPHDGTRRPILVNDVEVGAIIASPVERLTRNTDINFD
MQQRRASWMIVALSTLLAALATFLLARGLLAPVKRLVEGTHRLAAGDFTTRVTPTSADELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRQFTPESVTSLQAEVGTLTKLVDDLHQLSLSDEGALAYQKTTVDLVPLLE
VAGGAFRERFTSRGLTLHYALPDSMTVFGDPDRLMQLFNNLLENSLRYTDSGGGLHISAEQRDKSLFLTFADSAPGVSDE
QLQKLFDRFYRTEVSRNRASGGSGLGLAICVNIVHAHNGHLHAAHSPFGGVSITVELPLDRDLQREV

Sequences:

>Translated_467_residues
MKVWRPGITGKLFLAIFATCIVLLISMHWAVRVSFERGFIDYIKHGNEQRLQMLGDALGDQYQQHGNWRFLRNNDRFVFQ
ILRSFEHDNDRDKPGPGMPPHGWRTQFWVVDQNGRVLVGPRGPVPHDGTRRPILVNDVEVGAIIASPVERLTRNTDINFD
MQQRRASWMIVALSTLLAALATFLLARGLLAPVKRLVEGTHRLAAGDFTTRVTPTSADELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRQFTPESVTSLQAEVGTLTKLVDDLHQLSLSDEGALAYQKTTVDLVPLLE
VAGGAFRERFTSRGLTLHYALPDSMTVFGDPDRLMQLFNNLLENSLRYTDSGGGLHISAEQRDKSLFLTFADSAPGVSDE
QLQKLFDRFYRTEVSRNRASGGSGLGLAICVNIVHAHNGHLHAAHSPFGGVSITVELPLDRDLQREV
>Mature_467_residues
MKVWRPGITGKLFLAIFATCIVLLISMHWAVRVSFERGFIDYIKHGNEQRLQMLGDALGDQYQQHGNWRFLRNNDRFVFQ
ILRSFEHDNDRDKPGPGMPPHGWRTQFWVVDQNGRVLVGPRGPVPHDGTRRPILVNDVEVGAIIASPVERLTRNTDINFD
MQQRRASWMIVALSTLLAALATFLLARGLLAPVKRLVEGTHRLAAGDFTTRVTPTSADELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRQFTPESVTSLQAEVGTLTKLVDDLHQLSLSDEGALAYQKTTVDLVPLLE
VAGGAFRERFTSRGLTLHYALPDSMTVFGDPDRLMQLFNNLLENSLRYTDSGGGLHISAEQRDKSLFLTFADSAPGVSDE
QLQKLFDRFYRTEVSRNRASGGSGLGLAICVNIVHAHNGHLHAAHSPFGGVSITVELPLDRDLQREV

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=467, Percent_Identity=88.6509635974304, Blast_Score=828, Evalue=0.0,
Organism=Escherichia coli, GI1786783, Length=293, Percent_Identity=29.0102389078498, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=28.3088235294118, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=27.6679841897233, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786912, Length=276, Percent_Identity=29.3478260869565, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=28.0487804878049, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790861, Length=306, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787374, Length=297, Percent_Identity=24.5791245791246, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87082128, Length=293, Percent_Identity=25.2559726962457, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=27.0491803278689, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081816, Length=254, Percent_Identity=29.5275590551181, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787894, Length=305, Percent_Identity=27.2131147540984, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788279, Length=305, Percent_Identity=25.2459016393443, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=27.6223776223776, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790551, Length=301, Percent_Identity=28.9036544850498, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=332, Percent_Identity=23.7951807228916, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=269, Percent_Identity=24.907063197026, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789403, Length=290, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52176; Mature: 52176

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVWRPGITGKLFLAIFATCIVLLISMHWAVRVSFERGFIDYIKHGNEQRLQMLGDALGD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHCCCHHHHHHHHHHHHH
QYQQHGNWRFLRNNDRFVFQILRSFEHDNDRDKPGPGMPPHGWRTQFWVVDQNGRVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECC
RGPVPHDGTRRPILVNDVEVGAIIASPVERLTRNTDINFDMQQRRASWMIVALSTLLAAL
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFLLARGLLAPVKRLVEGTHRLAAGDFTTRVTPTSADELGKLAQDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRQFTPESVTSLQAEVGTLTKLVDDLHQLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKTTVDLVPLLEVAGGAFRERFTSRGLTLHYALPDSMTVFGDPDRLMQLFNN
CCCCCEEEECCHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCEEECCHHHHHHHHHH
LLENSLRYTDSGGGLHISAEQRDKSLFLTFADSAPGVSDEQLQKLFDRFYRTEVSRNRAS
HHHHCCEEECCCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
GGSGLGLAICVNIVHAHNGHLHAAHSPFGGVSITVELPLDRDLQREV
CCCCCHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCCCHHCCC
>Mature Secondary Structure
MKVWRPGITGKLFLAIFATCIVLLISMHWAVRVSFERGFIDYIKHGNEQRLQMLGDALGD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHCCCHHHHHHHHHHHHH
QYQQHGNWRFLRNNDRFVFQILRSFEHDNDRDKPGPGMPPHGWRTQFWVVDQNGRVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECC
RGPVPHDGTRRPILVNDVEVGAIIASPVERLTRNTDINFDMQQRRASWMIVALSTLLAAL
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFLLARGLLAPVKRLVEGTHRLAAGDFTTRVTPTSADELGKLAQDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRQFTPESVTSLQAEVGTLTKLVDDLHQLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKTTVDLVPLLEVAGGAFRERFTSRGLTLHYALPDSMTVFGDPDRLMQLFNN
CCCCCEEEECCHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCEEECCHHHHHHHHHH
LLENSLRYTDSGGGLHISAEQRDKSLFLTFADSAPGVSDEQLQKLFDRFYRTEVSRNRAS
HHHHCCEEECCCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
GGSGLGLAICVNIVHAHNGHLHAAHSPFGGVSITVELPLDRDLQREV
CCCCCHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]