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The map label for this gene is baeR [H]

Identifier: 16765461

GI number: 16765461

Start: 2224537

End: 2225259

Strand: Direct

Name: baeR [H]

Synonym: STM2131

Alternate gene names: 16765461

Gene position: 2224537-2225259 (Clockwise)

Preceding gene: 16765460

Following gene: 16765462

Centisome position: 45.8

GC content: 53.8

Gene sequence:

>723_bases
ATGACTGAATTACCCATTGATGAAAACACGCCGCGCATTTTGATTGTTGAAGATGAACCCAAGCTGGGACAGCTGCTTAT
TGACTACTTACGCGCGGCGAGTTACGCCCCCACGCTCATCAATCATGGCGACAAGGTACTGCCGTATGTGCGTCAAACGC
CGCCGGATCTGATCCTGCTGGATCTGATGCTGCCGGGTACCGATGGTCTGACGCTATGCCGGGAGATTCGCCGTTTTTCC
GACATCCCCATTGTGATGGTCACGGCCAAAATCGAAGAGATCGACCGGCTGCTTGGGCTGGAAATCGGCGCCGATGATTA
TATCTGTAAGCCTTACAGCCCGCGCGAAGTCGTGGCCCGCGTGAAAACCATTTTGCGCCGCTGTAAACCGCAGCGCGAAC
TCCAGCAGCAGGATGCCGAAAGCCCGTTAATGATTGATGAAAGCCGCTTTCAGGCCTCCTGGTGTGGTAAAGCGCTGGAT
TTAACCCCCGCTGAATTCCGTCTGCTAAAAACCTTATCGCTTGAACCGGGTAAAGTTTTTTCCCGCGAGCAGTTGTTAAA
CCACCTCTACGACGACTACCGTGTGGTGACCGACCGTACCATCGACAGCCATATTAAAAACCTGCGCCGTAAACTGGAAT
CGCTGGATGCCGAACAGTCATTTATACGCGCGGTCTACGGGGTGGGATATCGCTGGGAAGCGGATGCGTGTCGCCTGGTA
TAA

Upstream 100 bases:

>100_bases
TACACGCGCATAACGGTCATCTTCACGCCGCTCATTCGCCTTTTGGCGGGGTTAGCATTACAGTAGAGTTACCGCTGGAT
CGCGATTTACAGAGAGAAGT

Downstream 100 bases:

>100_bases
TGATTATTGGCATAACAATAACAAGGTCGTAAGACGATATTTTCCGCCAACGCTATTCTGGCGGAATTAACACACTGCCC
TCTTTCCTTTGGCCGAGCGG

Product: DNA-binding transcriptional regulator BaeR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLINHGDKVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFS
DIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLMIDESRFQASWCGKALD
LTPAEFRLLKTLSLEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRLV

Sequences:

>Translated_240_residues
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLINHGDKVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFS
DIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLMIDESRFQASWCGKALD
LTPAEFRLLKTLSLEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRLV
>Mature_239_residues
TELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLINHGDKVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSD
IPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLMIDESRFQASWCGKALDL
TPAEFRLLKTLSLEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRLV

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=96.6666666666667, Blast_Score=469, Evalue=1e-134,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=41.7777777777778, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=40.1785714285714, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=36.5957446808511, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=36, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.1351351351351, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.6223175965665, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=32.1888412017167, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.5291479820628, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=32.2727272727273, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=32.7510917030568, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=32.2869955156951, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=29.5964125560538, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27594; Mature: 27463

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLINHGDKVLPYVRQTPPDLILL
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRELQQQDAESPLMIDESRFQASWCGKALDLTPAEFRLLKTLSLEPGKVF
HHHHHHHCCCHHHHHHHCCCCCEEECHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHH
SREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRLV
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCCCCCC
>Mature Secondary Structure 
TELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLINHGDKVLPYVRQTPPDLILL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRELQQQDAESPLMIDESRFQASWCGKALDLTPAEFRLLKTLSLEPGKVF
HHHHHHHCCCHHHHHHHCCCCCEEECHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHH
SREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRLV
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]