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The map label for this gene is yegB [H]

Identifier: 16765459

GI number: 16765459

Start: 2221725

End: 2223137

Strand: Direct

Name: yegB [H]

Synonym: STM2129

Alternate gene names: 16765459

Gene position: 2221725-2223137 (Clockwise)

Preceding gene: 16765458

Following gene: 16765460

Centisome position: 45.74

GC content: 54.49

Gene sequence:

>1413_bases
ATGACAGAACTTCCTGACAACACCCGCTGGCAACTCTGGATTGTGGCATTCGGCTTTTTTATGCAGTCGCTGGATACCAC
CATCGTCAACACTGCGCTGCCCTCCATGGCGAAAAGCCTGGGGGAAAGCCCGCTGCATATGCACATGGTAGTGGTGTCAT
ATGTTCTTACCGTCGCCGTAATGCTCCCCGCCAGCGGCTGGCTGGCAGATAAAATCGGCGTGCGTAATATCTTCTTTGCC
GCCATTGTGCTGTTCACGCTGGGTTCGCTGTTTTGCGCCCTCTCCGGCACGCTTAATCAACTGGTATTAGCGCGGGTTTT
ACAAGGCGTAGGCGGCGCGATGATGGTGCCGGTCGGACGCCTGACGGTCATGAAAATCGTGCCGCGCGCGCAATATATGG
CGGCGATGACCTTCGTCACCCTACCGGGACAGATCGGGCCGTTACTCGGCCCCGCGCTGGGCGGGGTGCTGGTGGAATAT
GCTTCATGGCACTGGATCTTTCTGATCAATATCCCGGTGGGAATTGTCGGCGCTATGGCGACCTTTATGCTGATGCCAAA
CTACATCATAGAGACCCGGCGCTTTGATCTGCCGGGGTTCCTGCTGTTAGCTATCGGCATGGCGGTACTCACGCTGGCGC
TGGACGGTAGTAAAAGCATGGGGATTTCGCCCTGGACATTAGCCGGACTTGCTGCGGGTGGCGCGGCAGCCATTCTGCTC
TATCTCTTCCATGCCAAAAAAAACTCAGGCGCGTTATTCAGCCTGCGATTGTTCCGCACGCCCACGTTTTCACTAGGGTT
GCTGGGCAGTTTTGCCGGGCGTATCGGCAGCGGTATGCTGCCGTTTATGACGCCGGTCTTTTTGCAAATTGGTCTTGGTT
TTTCACCGTTTCATGCCGGTTTGATGATGATCCCCATGGTGCTGGGCAGCATGGGAATGAAGCGGATTGTGGTGCAGATA
GTTAACCGTTTTGGCTATCGTCGGGTTCTGGTAGCGACCACGCTCGGACTGGCATTGGTTAGCCTGTTGTTTATGTCGGT
CGCGCTGCTCGGCTGGTATTATCTCCTGCCGCTGGTACTGCTTTTGCAGGGAATGGTGAACTCGGCGCGCTTTTCTTCCA
TGAACACCTTAACGCTAAAAGACCTTCCCGATACGCTGGCCAGCAGCGGCAATAGCTTATTATCGATGATTATGCAGCTC
TCGATGAGTATCGGCGTCACTATTGCCGGGATGCTGCTGGGTATGTTTGGCCAACAGCATATCGGGATAGACAGTAGCGC
CACACATCACGTCTTTATGTACACCTGGTTATGTATGGCGGTTATTATCGCGCTACCGGCGATAATTTTTGCCCGCGTGC
CGAACGATACACAGCAAAACATGGTCATTTCACGGCGTAAAAGGAGCCTGTAA

Upstream 100 bases:

>100_bases
GCCAGCTCCTGACGCTCTATACCACGCCGGTGGTGTACCTCTTTTTCGATCGTCTGCGGCTACGTTTTTCGCGTAAAAAT
AGCAAACCGGTAGTAGAGAT

Downstream 100 bases:

>100_bases
TGAAAGTCTGGCGGCCCGGAATCACCGGCAAGCTGTTTCTGGCGATCTTCGCCACCTGCATCGTGCTGCTGATCAGTATG
CATTGGGCCGTGCGCGTCAG

Product: multidrug efflux system protein MdtE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTELPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFA
AIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVTLPGQIGPLLGPALGGVLVEY
ASWHWIFLINIPVGIVGAMATFMLMPNYIIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILL
YLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQI
VNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQL
SMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL

Sequences:

>Translated_470_residues
MTELPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFA
AIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVTLPGQIGPLLGPALGGVLVEY
ASWHWIFLINIPVGIVGAMATFMLMPNYIIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILL
YLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQI
VNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQL
SMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
>Mature_469_residues
TELPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFAA
IVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVTLPGQIGPLLGPALGGVLVEYA
SWHWIFLINIPVGIVGAMATFMLMPNYIIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILLY
LFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQIV
NRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLS
MSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI1788392, Length=469, Percent_Identity=85.9275053304904, Blast_Score=775, Evalue=0.0,
Organism=Escherichia coli, GI1790195, Length=459, Percent_Identity=45.0980392156863, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1789042, Length=401, Percent_Identity=27.6807980049875, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788710, Length=422, Percent_Identity=27.4881516587678, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI87081983, Length=425, Percent_Identity=28.4705882352941, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322958, Length=174, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319770, Length=289, Percent_Identity=26.9896193771626, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321663, Length=150, Percent_Identity=30.6666666666667, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323735, Length=164, Percent_Identity=28.0487804878049, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325455, Length=125, Percent_Identity=31.2, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50793; Mature: 50662

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
7.2 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHH
LTVMKIVPRAQYMAAMTFVTLPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAMA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
TFMLMPNYIIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILL
HHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHH
YLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG
HHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
LMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVL
HHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLLGMFGQQH
HHHHHHHHHHHCCCCEEEHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TELPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHH
LTVMKIVPRAQYMAAMTFVTLPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAMA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
TFMLMPNYIIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILL
HHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHH
YLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG
HHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
LMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVL
HHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLLGMFGQQH
HHHHHHHHHHHCCCCEEEHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA