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The map label for this gene is atoC [H]

Identifier: 167625343

GI number: 167625343

Start: 4179608

End: 4181059

Strand: Reverse

Name: atoC [H]

Synonym: Shal_3432

Alternate gene names: 167625343

Gene position: 4181059-4179608 (Counterclockwise)

Preceding gene: 167625344

Following gene: 167625342

Centisome position: 79.99

GC content: 49.52

Gene sequence:

>1452_bases
ATGGATACAGTCCTAATTGTCGACGATAATCAAGCCGTGTGTAATGCACTGGCTTTAATGTTAGAGCTTAACGGTTATCA
AACGCTCACCTGTTTATCCCCTGATGTGGCCCTTGAGTTAGTGCTACTGCACGATGTGGCGCTGGTGCTGCAAGATATGA
ACTTTAGCCAAGATACGACCTCGGGCGGTGAGGGGGTAACGCTATTTTATGCCCTGCGCCAACTGCAGCCACAACTGCCA
ATAATCTTGCTAACCGCCTGGACTCAATTGGAAGTGGCGGTAGAGCTGGTGAAGGAGGGCGGAGCCGATTACATGGGTAA
ACCTTGGGATGATGCCAAGTTACTCAACAGCATCAGCAATTTGATTTCACTGCATCGTCTGTCTAAGGAAAATGCTCAGC
TGAGCCGAGTTGAAAGCCAGCGTATGGTGGCCATAAAAGATGCCGACCTTTGTGGAATGGTGTTTAACAGTGGCGCGATG
CAGCGCTGTGTCGACTTGGCCCTGCAGATTGCTCGCTCCGATGTATCGGTACTGATCACCGGCCCTAATGGTGCGGGCAA
AGATAAGCTTGCCGACATCATTCATGCTAACTCTCCTTTAAAGCATAAGCCGTTTATTAAGGTCAACATTGGCGCCTTGC
CGATGGATCTTTTAGAAGCGGAGCTTTTTGGCGCTGAGGCGGGGGCATTTACCGGAGCCACCAAGGCACGTATCGGACGA
TTCGAAGCGGCCGACGGTGGCACACTGTTTTTAGATGAGATAGGTAATCTGCCATTGTCTGGCCAAGTTAAGTTGCTCAG
GGTGCTGCAAACCGGAGAGTTTGAACGTTTAGGCAGCCACCAGACACGTAAGGTCAAGGTGCGGGTGATTAGTGCCACTA
ACGCGAATTTAGCCGAAGAGATCCAAACCGGGCGTTTTCGTGAAGACCTGTTTTACCGACTCAATGTGATTGAGCTAGCC
TTGCCGACCTTAAATGATCGCGTAGATGATATTCAGCCTTTGGTTGAGCACTTTATTGGTGCAGGCTTCTCCCTTAATCA
CCAAGCCTTGCAAGTGTTGCTGGCGCATCATTGGCCCGGTAATGTGCGTGAGCTGGAAAATGCCTGTAAGCGGGCGGTTA
TCTTGGCGCAAAGCAGCGTATTAAGCGTCGATGATTTTGGCTTAGTGCAGGGCCAAGTTAGCCTTGAGGCTAAGTCTTGC
ATAAGTGAAGTGGTGTGGCCTGCAAATAGTCAGGCAAAGATAAAGGTTGCGTCAGTTGACTCATCTGCTCAGTCTTCTAT
AGCGTCAAGGCCTGCAGGGAAAGAGACGCTTGAGAAATATACTGATGAAAAATCTGATATTCAAGCGGCATTAGATAGCC
ACAACGGCGTGATCGCAAGAGTCGCTAAATCTTTAGGCTTAAGCAGGCAGGCCTTGTATCGGCGCATGGATAAGTATGGG
ATTGATAAATAG

Upstream 100 bases:

>100_bases
ATATCTAAATGAAAGCCAAATGTGAGCAGAGCTTTAACTCTGTTTGGCTTTGAGTTAGTTTTATAATTAGTCAACTAACA
TAATAAATACTAAAGAGTTT

Downstream 100 bases:

>100_bases
CTTTATTTCAAGCTTTCTCTTTAACTTTCGGCAAGAGTGCCCCTATGAGCCAGATTAGTCATATTTCATTAAGAGTCAAA
CTGATCGCTAGCTGCGTATC

Product: Fis family two component sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MDTVLIVDDNQAVCNALALMLELNGYQTLTCLSPDVALELVLLHDVALVLQDMNFSQDTTSGGEGVTLFYALRQLQPQLP
IILLTAWTQLEVAVELVKEGGADYMGKPWDDAKLLNSISNLISLHRLSKENAQLSRVESQRMVAIKDADLCGMVFNSGAM
QRCVDLALQIARSDVSVLITGPNGAGKDKLADIIHANSPLKHKPFIKVNIGALPMDLLEAELFGAEAGAFTGATKARIGR
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHQTRKVKVRVISATNANLAEEIQTGRFREDLFYRLNVIELA
LPTLNDRVDDIQPLVEHFIGAGFSLNHQALQVLLAHHWPGNVRELENACKRAVILAQSSVLSVDDFGLVQGQVSLEAKSC
ISEVVWPANSQAKIKVASVDSSAQSSIASRPAGKETLEKYTDEKSDIQAALDSHNGVIARVAKSLGLSRQALYRRMDKYG
IDK

Sequences:

>Translated_483_residues
MDTVLIVDDNQAVCNALALMLELNGYQTLTCLSPDVALELVLLHDVALVLQDMNFSQDTTSGGEGVTLFYALRQLQPQLP
IILLTAWTQLEVAVELVKEGGADYMGKPWDDAKLLNSISNLISLHRLSKENAQLSRVESQRMVAIKDADLCGMVFNSGAM
QRCVDLALQIARSDVSVLITGPNGAGKDKLADIIHANSPLKHKPFIKVNIGALPMDLLEAELFGAEAGAFTGATKARIGR
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHQTRKVKVRVISATNANLAEEIQTGRFREDLFYRLNVIELA
LPTLNDRVDDIQPLVEHFIGAGFSLNHQALQVLLAHHWPGNVRELENACKRAVILAQSSVLSVDDFGLVQGQVSLEAKSC
ISEVVWPANSQAKIKVASVDSSAQSSIASRPAGKETLEKYTDEKSDIQAALDSHNGVIARVAKSLGLSRQALYRRMDKYG
IDK
>Mature_483_residues
MDTVLIVDDNQAVCNALALMLELNGYQTLTCLSPDVALELVLLHDVALVLQDMNFSQDTTSGGEGVTLFYALRQLQPQLP
IILLTAWTQLEVAVELVKEGGADYMGKPWDDAKLLNSISNLISLHRLSKENAQLSRVESQRMVAIKDADLCGMVFNSGAM
QRCVDLALQIARSDVSVLITGPNGAGKDKLADIIHANSPLKHKPFIKVNIGALPMDLLEAELFGAEAGAFTGATKARIGR
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHQTRKVKVRVISATNANLAEEIQTGRFREDLFYRLNVIELA
LPTLNDRVDDIQPLVEHFIGAGFSLNHQALQVLLAHHWPGNVRELENACKRAVILAQSSVLSVDDFGLVQGQVSLEAKSC
ISEVVWPANSQAKIKVASVDSSAQSSIASRPAGKETLEKYTDEKSDIQAALDSHNGVIARVAKSLGLSRQALYRRMDKYG
IDK

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=494, Percent_Identity=38.0566801619433, Blast_Score=288, Evalue=6e-79,
Organism=Escherichia coli, GI1790299, Length=492, Percent_Identity=35.3658536585366, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1790437, Length=396, Percent_Identity=39.6464646464646, Blast_Score=261, Evalue=5e-71,
Organism=Escherichia coli, GI1788905, Length=387, Percent_Identity=38.5012919896641, Blast_Score=241, Evalue=9e-65,
Organism=Escherichia coli, GI87082117, Length=368, Percent_Identity=40.4891304347826, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1789087, Length=348, Percent_Identity=39.367816091954, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1786524, Length=247, Percent_Identity=48.1781376518219, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789233, Length=331, Percent_Identity=38.6706948640483, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI87082152, Length=351, Percent_Identity=37.8917378917379, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI87081872, Length=228, Percent_Identity=44.2982456140351, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1787583, Length=395, Percent_Identity=32.4050632911392, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1789828, Length=275, Percent_Identity=32.3636363636364, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081858, Length=329, Percent_Identity=29.1793313069909, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52542; Mature: 52542

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTVLIVDDNQAVCNALALMLELNGYQTLTCLSPDVALELVLLHDVALVLQDMNFSQDTT
CCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCC
SGGEGVTLFYALRQLQPQLPIILLTAWTQLEVAVELVKEGGADYMGKPWDDAKLLNSISN
CCCCCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LISLHRLSKENAQLSRVESQRMVAIKDADLCGMVFNSGAMQRCVDLALQIARSDVSVLIT
HHHHHHHHHCCHHHHHHHHCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEE
GPNGAGKDKLADIIHANSPLKHKPFIKVNIGALPMDLLEAELFGAEAGAFTGATKARIGR
CCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHCCC
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHQTRKVKVRVISATNANLAEE
EECCCCCEEEHHHHCCCCCCCCHHHHHHHHCCCHHHHCCCCCEEEEEEEEEECCCCHHHH
IQTGRFREDLFYRLNVIELALPTLNDRVDDIQPLVEHFIGAGFSLNHQALQVLLAHHWPG
HHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
NVRELENACKRAVILAQSSVLSVDDFGLVQGQVSLEAKSCISEVVWPANSQAKIKVASVD
CHHHHHHHHHHHEEEECCCEEECCCCCEEECEEEHHHHHHHHHHCCCCCCCCEEEEEECC
SSAQSSIASRPAGKETLEKYTDEKSDIQAALDSHNGVIARVAKSLGLSRQALYRRMDKYG
CHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHC
IDK
CCC
>Mature Secondary Structure
MDTVLIVDDNQAVCNALALMLELNGYQTLTCLSPDVALELVLLHDVALVLQDMNFSQDTT
CCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCC
SGGEGVTLFYALRQLQPQLPIILLTAWTQLEVAVELVKEGGADYMGKPWDDAKLLNSISN
CCCCCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LISLHRLSKENAQLSRVESQRMVAIKDADLCGMVFNSGAMQRCVDLALQIARSDVSVLIT
HHHHHHHHHCCHHHHHHHHCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEE
GPNGAGKDKLADIIHANSPLKHKPFIKVNIGALPMDLLEAELFGAEAGAFTGATKARIGR
CCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHCCC
FEAADGGTLFLDEIGNLPLSGQVKLLRVLQTGEFERLGSHQTRKVKVRVISATNANLAEE
EECCCCCEEEHHHHCCCCCCCCHHHHHHHHCCCHHHHCCCCCEEEEEEEEEECCCCHHHH
IQTGRFREDLFYRLNVIELALPTLNDRVDDIQPLVEHFIGAGFSLNHQALQVLLAHHWPG
HHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
NVRELENACKRAVILAQSSVLSVDDFGLVQGQVSLEAKSCISEVVWPANSQAKIKVASVD
CHHHHHHHHHHHEEEECCCEEECCCCCEEECEEEHHHHHHHHHHCCCCCCCCEEEEEECC
SSAQSSIASRPAGKETLEKYTDEKSDIQAALDSHNGVIARVAKSLGLSRQALYRRMDKYG
CHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHC
IDK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]